| Entry |
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| Name |
molybdopterin adenylyltransferase;
MogA;
Cnx1 (ambiguous)
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| Class |
Transferases;
Transferring phosphorus-containing groups;
Nucleotidyltransferases
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| Sysname |
ATP:molybdopterin adenylyltransferase
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| Reaction(IUBMB) |
ATP + molybdopterin = diphosphate + adenylyl-molybdopterin [RN: R09726]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
diphosphate [CPD: C00013];
adenylyl-molybdopterin [CPD: C19848]
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| Comment |
Catalyses the activation of molybdopterin for molybdenum insertion. In eukaryotes, this reaction is catalysed by the C-terminal domain of a fusion protein that also includes molybdopterin molybdotransferase (EC 2.10.1.1). The reaction requires a divalent cation such as Mg2+ or Mn2+.
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| History |
EC 2.7.7.75 created 2011
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| Pathway |
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| Orthology |
| K03638 | molybdopterin adenylyltransferase |
| K03831 | molybdopterin adenylyltransferase |
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| Genes |
» show all
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| Reference |
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| Authors |
Nichols JD, Rajagopalan KV |
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| Title |
In vitro molybdenum ligation to molybdopterin using purified components. |
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| Journal |
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| Sequence |
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| Reference |
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| Authors |
Kuper J, Palmer T, Mendel RR, Schwarz G |
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| Title |
Mutations in the molybdenum cofactor biosynthetic protein Cnx1G from Arabidopsis thaliana define functions for molybdopterin binding, molybdenum insertion, and molybdenum cofactor stabilization. |
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| Journal |
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| Sequence |
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| Reference |
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| Authors |
Llamas A, Mendel RR, Schwarz G |
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| Title |
Synthesis of adenylated molybdopterin: an essential step for molybdenum insertion. |
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| Journal |
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| Sequence |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 2.7.7.75 |
| ExPASy - ENZYME nomenclature database: | 2.7.7.75 |
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