KEGG   ENZYME: 2.7.7.81
Entry
EC 2.7.7.81                 Enzyme                                 

Name
pseudaminic acid cytidylyltransferase;
PseF
Class
Transferases;
Transferring phosphorus-containing groups;
Nucleotidyltransferases
Sysname
CTP:5,7-diacetamido-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-nonulosonic acid cytidylyltransferase
Reaction(IUBMB)
CTP + 5,7-diacetamido-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-2-nonulopyranosonic acid = diphosphate + CMP-5,7-diacetamido-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-2-nonulopyranosonic acid [RN:R09843]
Reaction(KEGG)
R09843
Substrate
CTP [CPD:C00063];
5,7-diacetamido-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-2-nonulopyranosonic acid
Product
diphosphate [CPD:C00013];
CMP-5,7-diacetamido-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-2-nonulopyranosonic acid
Comment
Mg2+ is required for activity.
History
EC 2.7.7.81 created 2012
Pathway
ec00520  Amino sugar and nucleotide sugar metabolism
ec00541  O-Antigen nucleotide sugar biosynthesis
ec01100  Metabolic pathways
Orthology
K15899  pseudaminic acid cytidylyltransferase
Genes
ENC: ECL_03362
KPSE: IP581_14585(pseF)
SGOE: A8O29_008110(pseF)
PSHI: SAMEA2665130_0847(neuA)
EBF: D782_1587
PEC: W5S_3018
PRQ: CYG50_16680(pseF)
VEU: IXK98_09390(pseF)
VBR: A6E01_00900
VSC: VSVS12_00347(neuA)
VCC: FAZ90_14245(pseF)
VAQ: FIV01_00115(neuA2)
VZI: G5S32_14065(pseF)
PPR: PBPRA2709(HH0900)
GHO: AL542_04205(pseF) AL542_05060(pseF)
SALY: E8E00_03885(pseF) E8E00_04310(pseF)
SKS: FCN78_08995(pseF)
SCOT: HBA18_09405(pseF)
PFL: PFL_1623(pseF)
PPRO: PPC_1677(pseF)
PFO: Pfl01_1521(neuA2)
PMAN: OU5_5135
PPUU: PputUW4_03893(pseF)
PSEM: TO66_08065
PSOS: POS17_1652(pseF)
PSIL: PMA3_08475
PKE: DLD99_08360(pseF)
POJ: PtoMrB4_36540(rkpN)
PGY: AWU82_00575(pseF)
PATA: JWU58_20035(pseF)
PZE: HU754_009155(pseF)
PMOE: HV782_008625(pseF)
PSEP: C4K39_1701
PVW: HU752_009065(pseF)
PXA: KSS93_10575(pseF)
PTZ: HU718_008845(pseF)
PHV: HU739_010000(pseF)
MHC: MARHY2544(rkpN)
ABX: ABK1_0088
ADV: DJ533_18130(pseF)
SDN: Sden_1288
SBJ: CF168_14340(pseF)
SMAI: EXU30_16035(pseF)
SPOL: FH971_05630(pseF)
SBK: SHEWBE_3620(pseF)
SAES: HBH39_05125(pseF)
SLIT: JQC75_11620(pseF)
IAB: K5X84_03430(pseF)
CPS: CPS_2094
COV: EKO29_16600(pseF)
CBER: B5D82_01870(pseF)
PAT: Patl_3078
PDJ: D0907_14885(pseF)
PAGA: PAGA_a1090(neuA)
AMAL: I607_05015
AMAE: I876_05310
AMAO: I634_05335
AMAD: I636_05255
AMAI: I635_05225
AMAG: I533_04915
AMAC: MASE_04805
AAUS: EP12_05105
ALR: DS731_06375(pseF)
APEL: CA267_014200(pseF)
GNI: GNIT_2391(neuA)
GPS: C427_3691
CATE: C2869_15775(pseF)
SALM: D0Y50_04695(pseF)
SMAA: IT774_12395(pseF)
MVS: MVIS_3752(neuA)
MYA: MORIYA_3703(pseF)
MMAA: FR932_21315(pseF)
FPZ: LA55_1644
FNA: OOM_1615
FAD: CDH04_02725(pseF)
FMI: F0R74_04820(pseF)
PSAL: PSLF89_937
RHH: E0Z06_10250(pseF)
TVR: TVD_05110
GHL: GM160_03640(pseF)
HAM: HALO0900
HTT: HZS52_09350(pseF)
HCAM: I4484_11785(pseF)
PAUR: FGL86_11220(pseF) FGL86_13920(pseF)
MPRI: MP3633_0774(neuA)
MARD: IBG28_15620(pseF)
MFOI: JSY38_13755(pseF)
OAI: OLEAN_C14040(neuA)
OME: OLMES_3137(pseF)
ASA: ASA_0150(neuA)
ASR: WL1483_1130(pseF)
ADH: CK627_03145(pseF)
AALL: I6G90_07880(pseF)
KGE: TQ33_1403
THIN: CRN91_03205(pseF)
CDIZ: CEDIAZO_00255(neuA)
KKI: KKKWG1_1882(pseF)
KOA: H3L93_02575(pseF)
ECOR: SAMEA4412678_0511(neuA)
AFF: H3L97_09925(pseF)
CSTE: H3L98_05385(pseF)
CRZ: D1345_18315(pseF)
PHS: C2L64_17825(pseF)
PTER: C2L65_15655(pseF)
PEW: KZJ38_01885(pseF)
CARI: FNU76_22525(pseF)
BTRM: SAMEA390648700508(neuA)
CTES: O987_16660
MASZ: C9I28_00215(pseF)
MASY: DPH57_21455(pseF)
MALI: EYF70_30285(pseF)
DSU: Dsui_0081
NIV: JY500_12345(pseF)
ATW: C0099_02445(pseF)
TCL: Tchl_0901
AZQ: G3580_04540(pseF)
HPY: HP_0326
HPG: HPG27_307(neuA-1)
HPL: HPB8_1238(neuA3)
HPO: HMPREF4655_20568(pseF)
HPQ: hp2017_03341(neuA1)
HPW: hp2018_03361(neuA1)
HEF: HPF16_0333(neuA)
HPF: HPF30_0970(neuA)
HEQ: HPF32_0979(neuA)
HEX: HPF57_0378(neuA)
HPZ: HPKB_0333
HPX: HMPREF0462_0383(pseF)
HPYS: HPSA20_0361(pseF)
HEY: MWE_0406
HPYR: K747_10300
HPYI: K750_03215
HPYU: K751_05820
HPYM: K749_04025
HEB: U063_0667
HEZ: U064_0669
HHE: HH_0900(neuA)
HAC: Hac_0995(neuA_fragment_1)
HMS: HMU11730(neuA2)
HFE: HFELIS_15240(neuA2)
HCE: HCW_06090
HCM: HCD_02160
HCP: HCN_1778(neuA)
HCB: HCBAA847_2061(neuA)
HAD: CDV25_00840(pseF)
HCL: NCTC13205_00366(neuA)
HWI: A0Z60_00235(pseF)
WSU: WS2106
SULR: B649_00705
CJE: Cj1311(pseF)
CJB: BN148_1311(pseF)
CJJ: CJJ81176_1328(neuA)
CJU: C8J_1244(neuA2)
CJI: CJSA_1249(pseF)
CJM: CJM1_1283(neuA)
CJS: CJS3_1411
CJEJ: N564_01329
CJEU: N565_01368
CJEN: N755_01364
CJEI: N135_01400
CJER: H730_07495
CJV: MTVDSCj20_1306(pseF)
CJY: QZ67_01446(legF_1)
CJQ: UC78_1260(legF_1)
CJR: CJE1506(neuA)
CFT: CFF04554_1560(pseF)
CFV: CFVI03293_1576(pseF)
CFX: CFV97608_1682(pseF)
CFZ: CSG_16850
CAMP: CFT03427_1508(pseF)
CCV: CCV52592_0562(pseF)
CLA: CLA_1319(pseF)
CLR: UPTC16701_1290(pseF)
CLM: UPTC16712_1312(pseF)
CLQ: UPTC4110_1296(pseF)
CLN: UPTC3659_1532(pseF)
CLL: CONCH_1271(pseF)
CCQ: N149_1274(pseF)
CCF: YSQ_02290
CCY: YSS_07125
CCOI: YSU_02305
CCOF: VC76_06595(legF_1)
CCOO: ATE51_00942(legF_3)
CAJ: CIG1485E_1498(pseF)
CIS: CINS_1272(pseF)
CVO: CVOL_1304(pseF)
CPEL: CPEL_1425(pseF)
CAMR: CAQ16704_1322(pseF)
CSM: CSUB8521_1499(pseF)
CSF: CSUB8523_1595(pseF)
CHYO: CHH_1588(pseF)
CHV: CHELV3228_1547(pseF)
CSPF: CSF_1618(pseF)
CPIN: CPIN18020_0092(pseF)
CCUN: CCUN_0621(pseF)
CLX: CLAN_1235(pseF)
CAVI: CAV_1211(pseF)
CHW: A2J15_000515(pseF)
CAMZ: CVIC12175_0330(pseF)
CAMY: CSUIS_1322(pseF)
COJ: CORN_1393(pseF)
CUX: CUP3940_0288(pseF)
CRX: CRECT_0233(pseF)
CARM: CARM_1347(pseF)
CMUC: CMCT_0213(pseF)
CSHO: CSHOW_1833(pseF)
CINF: CINF_0741(pseF)
CNV: CNZW441b_1309(pseF)
SDL: Sdel_2210
SMUL: SMUL_3174(pseF)
SHAL: SHALO_2909
SULJ: SJPD1_2794
SULT: FA592_06770(pseF)
ABT: ABED_2055
ABL: A7H1H_2191(pseF)
ASK: EI285_09210(pseF)
ACRE: ACRYA_0125(pseF)
ALAN: ALANTH_2131(pseF)
APOC: APORC_1984(pseF)
AFC: AFAEC_0083(pseF)
ATHR: ATH_1862(pseF)
AAQI: AAQM_2374(pseF)
ASUI: ASUIS_2469(pseF)
AANA: AANAER_2796(pseF)
AVP: AVENP_2943(pseF)
ADZ: ADFLV_2833(pseF)
HYO: NNO_0334
NAM: NAMH_1607
NAP: C3L23_08300(pseF)
CMED: FE773_01440(pseF)
CPAF: C6V80_08990(pseF)
GEB: GM18_0746
GBN: GEOBRER4_36330(rkpN)
GER: KP004_16005(pseF)
DCB: C3Y92_09205(pseF) C3Y92_20345(pseF)
DSF: UWK_02416
SMI: BN406_06054(rkpN)
RHI: NGR_b09470(rkpN)
SFH: SFHH103_06317(rkpN)
SIX: BSY16_5648(pseF)
RGR: FZ934_17375(pseF)
ABAW: D5400_05885(pseF)
SPHT: K426_25885
ADO: A6F68_00418(neuA)
ERK: CD351_06875(pseF)
ERF: FIU90_06525(neuA)
BMX: BMS_0363(neuA)
PARH: I5S86_21265(pseF)
NARO: CFH99_19665(pseF)
ABAM: B1s21122_06190(pseF)
EYY: EGYY_09070(NeuA)
THEC: FFX45_00695(pseF)
ROL: CA51_18030(neuA)
LMAY: DPV73_15930(pseF)
BHF: C3V43_13555(pseF)
PARC: CI960_11580(pseF)
TFO: BFO_0116
COY: HF329_23625(pseF)
PGS: CPT03_16785(pseF)
EST: DN752_19910(pseF)
SPIR: CWM47_05770(pseF)
SPIK: EXU85_25850(pseF)
SPIB: G8759_29015(pseF)
STAE: HNV11_17745(pseF)
RUP: DTQ70_19105(pseF)
FAE: FAES_1129(Psb3)
FIN: KQS_04790
FLU: CHH17_13960(pseF)
MOX: DAMO_1788
 » show all
Reference
1  [PMID:16751642]
  Authors
Schoenhofen IC, McNally DJ, Brisson JR, Logan SM
  Title
Elucidation of the CMP-pseudaminic acid pathway in Helicobacter pylori: synthesis from UDP-N-acetylglucosamine by a single enzymatic reaction.
  Journal
Glycobiology 16:8C-14C (2006)
DOI:10.1093/glycob/cwl010
  Sequence
[hpy:HP_0326]
Other DBs
ExplorEnz - The Enzyme Database: 2.7.7.81
IUBMB Enzyme Nomenclature: 2.7.7.81
ExPASy - ENZYME nomenclature database: 2.7.7.81
BRENDA, the Enzyme Database: 2.7.7.81

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