KEGG   ENZYME: 2.7.8.11Help
Entry
EC 2.7.8.11                 Enzyme                                 

Name
CDP-diacylglycerol---inositol 3-phosphatidyltransferase;
CDP-diglyceride-inositol phosphatidyltransferase;
phosphatidylinositol synthase;
CDP-diacylglycerol-inositol phosphatidyltransferase;
CDP-diglyceride:inositol transferase;
cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:myo-inositol 3-phosphatidyltransferase;
CDP-DG:inositol transferase;
cytidine diphosphodiglyceride-inositol phosphatidyltransferase;
CDP-diacylglycerol:myo-inositol-3-phosphatidyltransferase;
CDP-diglyceride-inositol transferase;
cytidine diphosphoglyceride-inositol phosphatidyltransferase;
cytidine diphosphoglyceride-inositol transferase
Class
Transferases;
Transferring phosphorus-containing groups;
Transferases for other substituted phosphate groups
BRITE hierarchy
Sysname
CDP-diacylglycerol:myo-inositol 3-phosphatidyltransferase
Reaction(IUBMB)
CDP-diacylglycerol + myo-inositol = CMP + 1-phosphatidyl-1D-myo-inositol [RN:R01802]
Reaction(KEGG)
Substrate
CDP-diacylglycerol [CPD:C00269];
myo-inositol [CPD:C00137]
Product
CMP [CPD:C00055];
1-phosphatidyl-1D-myo-inositol [CPD:C01194]
History
EC 2.7.8.11 created 1972, modified 1976
Pathway
ec00562  Inositol phosphate metabolism
ec00564  Glycerophospholipid metabolism
ec01100  Metabolic pathways
Orthology
K00999  CDP-diacylglycerol--inositol 3-phosphatidyltransferase
Genes
HSA: 10423(CDIPT)
PTR: 454028(CDIPT)
PPS: 100974496(CDIPT)
GGO: 101152971(CDIPT)
PON: 100443337(CDIPT)
NLE: 100601495(CDIPT)
MCC: 707141(CDIPT)
MCF: 102125964(CDIPT)
CSAB: 103230727(CDIPT)
RRO: 104681381(CDIPT)
RBB: 108535384(CDIPT)
CJC: 100398398(CDIPT)
SBQ: 101029360(CDIPT)
MMU: 52858(Cdipt)
RNO: 192260(Cdipt)
CGE: 100750801(Cdipt)
NGI: 103726369(Cdipt)
HGL: 101714318(Cdipt)
CCAN: 109682578(Cdipt)
OCU: 100341003(CDIPT)
TUP: 102477688(CDIPT)
CFA: 489940(CDIPT)
AML: 100475176(CDIPT)
UMR: 103657844(CDIPT)
ORO: 101364778(CDIPT)
FCA: 101097119(CDIPT)
PTG: 102959250(CDIPT)
AJU: 106967534(CDIPT)
BTA: 515135(CDIPT)
BOM: 102286337(CDIPT)
BIU: 109578730(CDIPT)
PHD: 102319578(CDIPT)
CHX: 100861029(CDIPT)
OAS: 101119178(CDIPT)
SSC: 100312963(CDIPT)
CFR: 102522807(CDIPT)
CDK: 105102752(CDIPT)
BACU: 103010812(CDIPT) 103020340
LVE: 103083783 103091638(CDIPT)
OOR: 101274420(CDIPT)
ECB: 100065899(CDIPT)
EPZ: 103547198(CDIPT)
EAI: 106845616(CDIPT)
MYB: 102238844(CDIPT)
MYD: 102758294(CDIPT)
HAI: 109385991(CDIPT)
RSS: 109459862(CDIPT)
PALE: 102896359(CDIPT)
LAV: 100657287(CDIPT)
TMU: 101346778
MDO: 100012283(CDIPT)
SHR: 100915310(CDIPT)
OAA: 100087110(CDIPT)
CJO: 107307611(CDIPT)
PHI: 102106909(CDIPT)
AMJ: 102564407(CDIPT)
PSS: 102461027(CDIPT)
CPIC: 101938540(CDIPT)
ACS: 100565327(cdipt)
PVT: 110081835(CDIPT)
PBI: 103062530(CDIPT)
GJA: 107117423(CDIPT)
XLA: 414725 443837(cdipt.L)
XTR: 779827(cdipt)
NPR: 108789162(CDIPT)
DRE: 404620(cdipt)
CCAR: 109110357(cdipt)
IPU: 100528412(cdipt) 108278459(cdipt)
AMEX: 103029119(cdipt) 103039493
TRU: 101063128(cdipt)
LCO: 104938641(cdipt)
NCC: 104963085(cdipt)
MZE: 101482332(cdipt)
OLA: 101167290(cdipt)
XMA: 102230947(cdipt)
PRET: 103469485(cdipt)
NFU: 107380732 107394984(cdipt)
CSEM: 103377748 103393460(cdipt)
LCF: 108877955(cdipt)
HCQ: 109513796(cdipt)
BPEC: 110164200 110169275(cdipt)
SASA: 106600754(cdipt)
ELS: 105008260(cdipt) 105012953
SFM: 108941678(cdipt)
LCM: 102354732 102356375(CDIPT)
CMK: 103180647(cdipt)
SPU: 593468
SKO: 100372918
DME: Dmel_CG9245(Pis)
DSI: Dsimw501_GD15785(Dsim_GD15785)
MDE: 101900170
AAG: 5563812
AME: 411408
BIM: 100744347
BTER: 100648730
SOC: 105199026
AEC: 105147787
ACEP: 105625261
PBAR: 105424261
HST: 105183387
CFO: 105254309
LHU: 105673542
PGC: 109857455
NVI: 103317958
TCA: 655531
DPA: 109541257
NVL: 108569377
BMOR: 101744653
PMAC: 106711092
PRAP: 110991425
PXY: 105386874
API: 100165692
DNX: 107166834
ZNE: 110836583
TUT: 107367578
CEL: CELE_Y46G5A.5(pisy-1)
CBR: CBG08048(Cbr-pisy-1)
BMY: Bm1_49000
OBI: 106868977
SHX: MS3_04539
HMG: 105844917
AQU: 100636019
ATH: AT1G68000(PIS1) AT4G38570(PIS2)
THJ: 104824762
CPAP: 110816444
TCC: 18607542
GRA: 105785923
EGR: 104418949
VRA: 106755555
VAR: 108339010
CCAJ: 109798755
CAM: 101509970
LJA: Lj3g3v3410080.1(Lj3g3v3410080.1)
PPER: 18771371
PMUM: 103341277
PAVI: 110756833
ZJU: 107427341
CSV: 101219739
CMO: 103497336
MCHA: 111015459
RCU: 8270671
JCU: 105641794
HBR: 110663631
POP: 18102164
VVI: 100255504
SLY: 101255609
SPEN: 107027011
SOT: 102577577
CANN: 107852074
NSY: 104238528
NTO: 104091779
SIND: 105173030
SOE: 110797146
NNU: 104610234
OSA: 4328140
DOSA: Os02t0123600-01(Os02g0123600) Os06t0492000-01(Os06g0492000)
OBR: 102714804
ATS: 109762313(LOC109762313)
ZMA: 100136826 542548(PIS)
MUS: 104000419
DCT: 110114996
CRE: CHLREDRAFT_186369(PIS1)
MNG: MNEG_2701
APRO: F751_0445
SCE: YPR113W(PIS1)
ERC: Ecym_1247
KMX: KLMA_50434(PIS1)
NCS: NCAS_0A11560(NCAS0A11560)
NDI: NDAI_0A04730(NDAI0A04730)
TPF: TPHA_0D02940(TPHA0D02940) TPHA_0D03985(TPHA0D03985)
TBL: TBLA_0F01660(TBLA0F01660)
TDL: TDEL_0F03180(TDEL0F03180)
KAF: KAFR_0A05490(KAFR0A05490)
PIC: PICST_28132(PIS1)
CAL: CAALFM_C405210WA(CaO19.6860)
CAUR: QG37_01448
NCR: NCU09192
NTE: NEUTE1DRAFT90572(NEUTE1DRAFT_90572)
MGR: MGG_08368
MAW: MAC_07243
MAJ: MAA_08850
CMT: CCM_05258
BFU: BCIN_05g01110(Bcpis1)
MBE: MBM_07668
ANI: AN0913.2
ANG: ANI_1_1918014(An01g14140)
TVE: TRV_02075
PTE: PTT_07462
SPO: SPAC1D4.08(pis1)
CNE: CNH00510
CNB: CNBL0490
ABP: AGABI1DRAFT111328(AGABI1DRAFT_111328)
ABV: AGABI2DRAFT190550(AGABI2DRAFT_190550)
MGL: MGL_2253
DFA: DFA_00129
EHI: EHI_069630(194.t00007)
PYO: PY17X_1415800(PY06949)
PCB: PCHAS_141590(PC106162.00.0)
TAN: TA15380
TPV: TP02_0830
BBO: BBOV_II005250(18.m06434)
CPV: cgd8_560
SMIN: v1.2.011363.t1(symbB.v1.2.011363.t1)
MJL: Mjls_2283
NCA: Noca_2380
CHON: NIES4102_21210(pgsA_1)
AAS: Aasi_1236
 » show all
Taxonomy
Reference
1  [PMID:41587]
  Authors
Bleasdale JE, Wallis P, MacDonald PC, Johnston JM.
  Title
Characterization of the forward and reverse reactions catalyzed by CDP-diacylglycerol:inositol transferase in rabbit lung tissue.
  Journal
Biochim Biophys Acta 575:135-47 (1979)
DOI:10.1016/0005-2760(79)90139-5
Reference
2  [PMID:4293959]
  Authors
Prottey C, Hawthorne JN.
  Title
The biosynthesis of phosphatidic acid and phosphatidylinositol in mammalian pancreas.
  Journal
Biochem J 105:379-92 (1967)
Reference
3  [PMID:4295616]
  Authors
Salway JG, Harwood JL, Kai M, White GL, Haworne JN.
  Title
Enzymes of phosphoinositide metabolism during rat brain development.
  Journal
J Neurochem 15:221-6 (1968)
DOI:10.1111/j.1471-4159.1968.tb06200.x
Reference
4  [PMID:18462]
  Authors
Takenawa T, Egawa K.
  Title
CDP-diglyceride:inositol transferase from rat liver. Purification and properties.
  Journal
J Biol Chem 252:5419-23 (1977)
Other DBs
ExplorEnz - The Enzyme Database: 2.7.8.11
IUBMB Enzyme Nomenclature: 2.7.8.11
ExPASy - ENZYME nomenclature database: 2.7.8.11
BRENDA, the Enzyme Database: 2.7.8.11
CAS: 9027-01-4

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