KEGG   ENZYME: 2.7.8.24
Entry
EC 2.7.8.24                 Enzyme                                 
Name
phosphatidylcholine synthase;
CDP-diglyceride-choline O-phosphatidyltransferase
Class
Transferases;
Transferring phosphorus-containing groups;
Transferases for other substituted phosphate groups
Sysname
CDP-diacylglycerol:choline O-phosphatidyltransferase
Reaction(IUBMB)
CDP-diacylglycerol + choline = CMP + phosphatidylcholine [RN:R05794]
Reaction(KEGG)
R05794
Substrate
CDP-diacylglycerol [CPD:C00269];
choline [CPD:C00114]
Product
CMP [CPD:C00055];
phosphatidylcholine [CPD:C00157]
Comment
Requires divalent cations, with Mn2+ being more effective than Mg2+.
History
EC 2.7.8.24 created 2001
Pathway
ec00564  Glycerophospholipid metabolism
ec01110  Biosynthesis of secondary metabolites
Orthology
K01004  phosphatidylcholine synthase
Genes
PPAVLOZ86_18715
PAEPA3857(pcs)
PAEVN297_3983
PAEIN296_3983
PAUPA14_14110(pcs)
PAPPSPA7_1254
PAGPLES_11171(pcs)
PAFPAM18_1081(pcs)
PNCNCGM2_5046(pcs)
PAEBNCGM1900_1117(pcs)
PDKPADK2_05030
PSGG655_05410
PRPM062_20395
PAEPPA1S_05535
PAERPA1R_gp1751
PAEMU769_05570
PAELT223_05485
PAESSCV20265_1140
PAEUBN889_04288(pcs)
PAEGAI22_28080
PAECM802_3981
PAEOM801_3849
PMYPmen_3554
PMKMDS_3820
PREPCA10_15410
PPSEBN5_1012(pcs)
PFUWKF707C_16390
PCQPcP3B5_50360(pcs)
PMUIG4G71_09155
PFVPsefu_1073
PORAPT59_03915
PSTPSPTO_1000
PSBPsyr_0866
PSYRN018_21340
PSPPSPPH_0901
PSAVPSA3335_07925
PAMGBKM19_006885
PCIPCH70_08470
PAVLBKM03_05890
PVDCFBP1590__4443(pcs)
PCABJGS08_04620
PCOFPOR16_19815
PTREI9H09_04210
PSYIMME58_04155
PFLPFL_4055(pcs)
PPRCPFLCHA0_c41140(pcs)
PPROPPC_4154
PFNHZ99_01915
PFOPfl01_2093(pcs)
PFSPFLU_2780
PFCPflA506_2915(pcs)
PPZH045_07365
PFBVO64_0110
PMANOU5_5911
PTVAA957_01355
PVRPverR02_13995
PAZOAYR47_21240
POIBOP93_13765
PRXHRH33_12705
PFWPF1751_v1c24430(pcs)
PFFPFLUOLIPICF724510
PFXA7318_10630
PLULFOB45_12660
PPUUPputUW4_02019
PDRH681_19180
PSKU771_14740
PKCPKB_0999
PCHEY04_11160
PCZPCL1606_37570
PCPJM49_18795
PRHLT40_09830
PSESPSCI_0942
PSEMTO66_11955
PSOSPOS17_4149
PKRAYO71_18925
PFKPFAS1_00260
PANRA7J50_2660
PPSLBJP27_18350
PSETTHL1_1610
PSILPMA3_17310
PYMAK972_2511
PKEDLD99_11100
PALLUYA_18350
PUMHGP31_12785
POJPtoMrB4_44120(pcs)
PGGFX982_04095
PGYAWU82_18360
PLALFXN65_06915
PSEJHNQ25_07130
PEZHWQ56_12965
PKHJLK41_19520
PTYJWV26_04580
PMAOPMYSY11_0174(pcs)
PATAJWU58_11340
PZEHU754_018545
PMOEHV782_011780
PSEPC4K39_5991
PTRTHU722_0013750
PSAMHU731_002810
PTZHU718_011940
PSHHHU773_012480
PHVHU739_007100
PASGKSS96_13945
PAZEKSS91_11065
PWZJ7655_16150
PTWTUM18999_48370(pcs)
PIEHU724_017320
PGFJ0G10_12425
PCAVD3880_05765
EMODM558_14680
ALGAQULUS_01700(pcsA)
ASIPAQUSIP_01590(pcsA)
LPNlpg1584
LPHLPV_1721(lidK)
LPOLPO_1604(lidK)
LPULPE509_01613
LPMLP6_1562
LPFlpl1441(lidK)
LPPlpp1542(lidK)
LPCLPC_1009(lidK)
LPAlpa_02301(lidK)
LPElp12_1522
LLOLLO_1806(lidK)
LFALFA_1639(pcsA)
LHALHA_1557
LOKLoa_01524
LCDclem_07125(pcsA)
LSHCAB17_13105
LLG44548918_01204(lidK)
LIBE4T55_14535
LGTE4T54_01380
LJRNCTC11533_01512(lidK)
LCJNCTC11976_02146(lidK)
LWASAMEA4504053_1812(lidK)
LSSNCTC12082_00387(lidK)
LADLNCTC12735_01014(lidK)
LANTTUM19329_18540(pcsA)
LLYJ2N86_07740
TMCLMI_1459
FTUFTT_1563(pcs)
FTQRO31_1837
FTFFTF1563(pcs)
FTWFTW_0364
FTRNE061598_08770
FTTFTV_1491(pcs)
FTGFTU_1576(pcs)
FTLFTL_0545
FTHFTH_0547(pcs)
FTAFTA_0578
FTSF92_02975
FTIFTS_0547(pcs)
FTOX557_02925
FTCDA46_140
FTVCH67_856
FTZCH68_589
FTMFTM_0336(pcs)
FTNFTN_1471(pcs)
FTXAW25_530
FTDAS84_1029
FTYCH70_459
FCFFNFX1_1508
FCNFN3523_1538
FHIFSC454_07595
FPHFphi_1204
FPTBZ13_801
FPIBF30_1451
FPMLA56_987
FPXKU46_108
FPZLA55_1706
FPJLA02_822
FRTF7308_0800
FNAOOM_0755
FNLM973_08560
FRFLO80_08275
FPERACH24_00625
FHACDV26_09355
FRXF7310_02590
FRMBBG19_0314
FRCKX01_793
FADCDH04_08365
FMIF0R74_06290
FOOCGC45_01575
FNNFSC774_04900
FSRKQR59_07670
FGUSD28_06950
AFRIE3E15_01490
AIIE4K63_06290
HCSFF32_03645
HAKKO116_00712
HAMHALO0732
HHHCLM76_07880
HAGBB497_05855
HALKCUU95_08515
HVNEI420_17660
HOLHORIV_61550(pcs)
HSRHSBAA_59160
HMDCTT34_16225
HAXIHAALTHF_15960n(pcs)
HTTHZS52_08450
HPIZGYM47_15610
HPROLMS44_19810
ZPLZBT109_1182
HAAA5892_14255
CHROCXB49_03520
PLGNCTC10937_03620(pcs)
DRTDret_1145
MLOmll0506
MLNA9174_22970
MCIMesci_3870
MOPMesop_4491
MAMMesau_04128
MAMOA6B35_19205
MESWA9K65_020480
MESMEJ066_23650
MESPC1M53_27805
MHUAMCHK_2231
MJREB229_22995
MERDEB233_19870
MESRFGU64_03255
MESOBSQ44_14015
MESMeso_1695
HOEIMCC20628_02062
AAKAA2016_3694
AMIHCO731_03463(pcs)
PHTBLM14_08950
PHYLHB779_14255
NIYFQ775_19585
NKIKW403_17575
PLAPlav_1484
PMOBHG718_15045
RBSRHODOSMS8_02799(pcs)
SMESMc00247(pcs)
SMKSinme_1576
SMQSinmeB_1418
SMXSM11_chr1736(pcs)
SMIBN406_01424(pcs)
SMEGC770_GR4Chr1713
SMELSM2011_c00247(pcs)
SMERDU99_09125
SMDSmed_1420
RHINGR_c14490(pcs)
SFHSFHH103_01344(pcs)
SFDUSDA257_c36660(pcs)
SIXBSY16_1211(pcs)
SAMESAMCFNEI73_Ch1722(pcs)
SINOSS05631_c14470
EADOV14_2758(pcs)
EAHFA04_06765
ESJSJ05684_c14450
EAKEKH55_1363
EMXFKV68_09390
ATUAtu1793(pcs)
ARAArad_2343(pcs)
ATAAWN88_13900
AGRAGROH133_06819(pcs)
ATFAch5_17200(pcs)
AVIAvi_2165(pcs)
AGCBSY240_566(pcs)
AROB0909_04050
AGTEYD00_07040
ALFCFBP5473_08455
ARUIG6M88_02260
AVQHRR99_09325
RETRHE_CH02079(pcs)
RECRHECIAT_CH0002129(pcs)
RELREMIM1_CH02087(pcs)
REPIE4803_CH02091(pcs)
REIIE4771_CH02179(pcs)
RLERL2370(pcs)
RLTRleg2_1714
RLGRleg_1898
RLBRLEG3_20045
RLURLEG12_19890
RTRRTCIAT899_CH08795(pcs)
RIRBN877_I1759(pcs)
RPUSCFBP5875_07570
RHLLPU83_2441(pcs)
RGARGR602_CH01873(pcs)
RHNAMJ98_CH02131(pcs)
RPHAAMC79_CH02203(pcs)
RHXAMK02_CH02141(pcs)
RHVBA939_03645
RHKKim5_CH02191(pcs)
REZAMJ99_CH02209(pcs)
RJGCCGE525_10065
RHRCKA34_12240
RGRFZ934_06285
RADCO657_08595
ROYG3A56_01130
RIIFFM53_001770
RHIDFFM81_010965
RBQJ2J99_10940(pcs)
RLNJ0663_19800(pcs)
RBANJ2J98_10420(pcs)
RRGJ3P73_12080(pcs)
RLSHB780_15555
RROSD4A92_17550
NGLRG1141_CH17460
NGGRG540_CH17860
NEOCYG48_06975
NENNCHU2750_18870(pcs)
RHTNT26_1825(pcs)
RFVRFYW14_01884
LASCLIBASIA_03680
LAAWSI_03545
LATCGUJ_03680
LSOCKC_04930
LCCB488_05590
LARlam_551(pssA)
LAUG293_00760
SHZshn_09545
SZOK8M09_07845(pcs)
SOJK6301_06955(pcs)
ABAWD5400_11460
PDESFE840_013305
KAIK32_21860
BMEBMEII0695
BMELDK63_2546(pcs)
BMIBMEA_B0545
BMZBM28_B0544
BMGBM590_B0544
BMWBMNI_II0538
BMEEDK62_2861(pcs)
BMFBAB2_0668
BMBBruAb2_0652(pcs)
BMCBAbS19_II06250
BAABAA13334_II01275
BABODK55_2636(pcs)
BABRDO74_3054(pcs)
BABTDK49_2601(pcs)
BABBDK48_3161(pcs)
BABUDK53_2641(pcs)
BABSDK51_2123(pcs)
BABCDO78_2416(pcs)
BMSBRA0572(pcs)
BSIBS1330_II0567(pcs)
BSFBSS2_II0544(pcs)
BSUIBSSP1_II0527
BSUPBSPT1_II0525
BSUVBSPT2_II0528
BSUCBSSP2_II0534
BMTBSUIS_B0568
BSZDK67_2566(pcs)
BSVBSVBI22_B0566(pcs)
BSWIY71_00740 IY71_13930
BSGIY72_13465
BOVBOV_A0538
BCSBCAN_B0572
BSKBCA52141_II0369
BOLBCOUA_II0572(pcs)
BCARDK60_2283(pcs)
BCASDA85_13225
BMRBMI_II566(pcs)
BPPBPI_II624(pcs)
BPVDK65_3058(pcs)
BCETV910_200681
BCEEV568_200779
BVLBF3285c2_0104(pcs)
BRUBFS01_13545
BRJBKD03_04145
OINIAR37_18100
BIOBR141012304_20493(pcs)
OANOant_3634
OAHDR92_2849(pcs)
OPSA8A54_13250
OCHCES85_3969(pcs)
OCRHGK82_20660
OCLGTN27_17210
PSCQKHQ08_08785
BJAbll4585(pcs)
BJUBJ6T_50980
BJPRN69_24855
BRABRADO3781
BBTBBta_4148
BRSS23_35260(pcs)
AOLS58_38290
BRCBCCGELA001_19630
BRADBF49_6912
BICLMTR13_19940
BROBRAD285_3591
BRKCWS35_24365
BOTCIT37_30965
BRQCIT40_15695
BGQX265_19725
BGZXH91_17660
BSYMCIT39_14820
BBETF8237_32420
BARHWN72_26105
BVZBRAD3257_4433(pcs)
BELBE61_57330(pcs)
BDGLPJ38_24990
BSEPHAP48_0038210
BQBJ4P68_0039265
RPARPA2672
RPBRPB_2842
RPCRPC_2618
RPDRPD_2630
RPERPE_2798
RPTRpal_2947
RPXRpdx1_2835
NWINwi_1506
NHANham_2046
OCAOCAR_6201
OCGOCA5_c18300
OCOOCA4_c18300
VGOGJW-30_1_03178(pcs)
TRBHB776_07345
BVVBHK69_22835
BOIBLM15_04025
BHEBH08530(pcsA)
BHNPRJBM_00839(pcsA)
BHSBM1374165_00938(pcsA)
BQUBQ06040(pcsA)
BQRRM11_0578
BBKBARBAKC583_0817(pcs)
BTRBT_1173
BTXBM1374166_01107(pcsA)
BGRBgr_10750(pcsA)
BCDBARCL_0765(pcsA)
BAUSBAnh1_06510(pcs)
BVNBVwin_07600(pcs)
BANCPU02_0969
BAPIBBC0122_010220
BARTBJB15x_006150
BARABA1379B_005510
BARWBWD162_007220
BARRBra60_006330
BAROB11Cv2_006330
BARJBJB63x_006090
BEZNCTC12898_00727(pcs)
BARND1092_04200
BKYD1093_06670
BALSHWV54_00540
BTAYLAJ60_01290
SNOSnov_1703
STARG3545_03125
LNEFZC33_34330
ANCGBB76_03975
APRAG3A50_20525
APOLK9D25_16025
RHJHZY79_12790
RVARvan_1366
RHZRHPLAN_35870
BVRBVIR_1798
BLAGBLTE_09730(pcs)
MSCBN69_0578
MROSEHO51_08950
PLEOOHA_1_00779(pcs)
HDIHDIA_2460(pcs)
MEYTM49_16295
MAADAZF01_09880
MMEDMame_03140(pcs)
MLUTJET14_09690
AUAM673_10980
AALAIGS74_13410
AALMLUX29_15260
AUZSa4125_21180(pcs)
AUBLXB15_08765
BRND1F64_11615
THDBHV28_08120(pcs)
PSINCAK95_23520
TSOIZ6_16930
PSFPSE_3186(pcs)
PPHRAPZ00_18845
LAPACP90_14715
LABRCHH27_05785
LABPFJ695_18250
LABTFIU93_20410(pcs)
LAGGB0E33_26545
SIWGH266_00885
PHRC6569_07710
PSTGE8M01_31665
ACUTMRB58_01460
SILSPO3131(pcs)
SITTM1040_2382
RUAD1823_09850
RUTFIU92_03430(pcs)
JANJann_1029
RDERD1_2077(pcs)
RPONG3256_04780
PGAPGA1_c05740(pcs)
PGLPGA2_c05300(pcs)
PGDGal_02932
PHPPhaeoP97_02782(pcs)
PPICPhaeoP14_00496(pcs)
PHQD1820_15980
OATOAN307_c08730
OAROA238_c32160
OTMOSB_06900(pcs)
OCTFTO60_12255
LMDMETH_13975
LEJETW24_14815
LAQUR2C4_04130
LEVETW23_04385
REDroselon_01929
CMARIMCC12053_2730
MALGMALG_02844
YPACCEW88_02900
YANAYJ57_09940
TPROGa0080559_TMP1448
PABYGa0080574_TMP2982
SUAMBOO69_02495
SULZC1J03_06315
SULIC1J05_15530
SULDB5M07_05870
SPOTG6548_04775
SMEDJNX03_08830
SINLDSM14862_02287(pcs_1)
SPSESULPSESMR1_02217(pcs)
TOMBWR18_10810
RMMROSMUCSMR3_00993(pcs)
ROKRAK1035_3861
RIDRIdsm_00235(pcs)
ROMEI983_13940
ROHFIU89_04135(pcs1)
AHTANTHELSMS3_01509(pcs)
SAGUCDO87_07435
THAACFI11_17440
OCDFHY55_07430
MARUFIU81_13645(pcs)
ROTFIV09_03790(pcs)
RMHLVO79_01955
MALUKU6B_50650
TGLHFZ77_17145
HATRC74_02730
PALXGQA70_01955
LSALKBK07_13165
RSPRSP_0565
RSHRsph17029_2217
RSQRsph17025_0497
RSKRSKD131_1903
CAZTLV780_02180
RCPRCAP_rcc03206(pcs)
RHPLPB142_13500
RBLB6K69_06440
PDEPden_0811
PAMIJCM7686_3158
PYEA6J80_07780
PCONB0A89_03865
PZHCX676_08185
PAROCUV01_14485
PARUCYR75_08490
PAMNJCM7685_2671
PARSDRW48_01230
PARREOJ32_05240
PAAKFIU66_12300
PKDF8A10_08795
PPANESD82_17825
PLIAE4191_13355
PSANHGN31_05640
PMAUCP157_02518(pcs)
PTPRCA23_c09120(pcs)
RMBK529_011380
DAAAKL17_0319
DONBSK21_08795
THWBMG03_18165
TECAKL02_018525
LVSLOKVESSMR4R_00456(pcs)
RBGBG454_14275
GEHHYN69_03210
GFUKM031_05910
TAWEI545_06035
SALOEF888_01915
SEDIEBB79_04150
HMLHmaOT1_03015
BOOE2K80_10045
PSEBEOK75_05085
PPRUFDP22_04590
PAEDG5B38_15020
MONG8E03_14830
PAMOBAR1_11610
PSHQF3W81_10430
PALWPSAL_001170(pcs)
PPAFI8N54_12770
PGVSL003B_2244
CACTHZ995_02825
RBZB9057_04560
THASC6Y53_15605
HDHG5B40_10700
CMAGCBW24_14575
FAPGR316_10665
GCEKYE46_15355
NSMJO391_03460
ACROK3J57_01790
SECHB18_02330
SLUTH9L13_11105
SPIIG7077_02015
SPHSETR14_18840
AZLAZL_005000(pcs)
ALIAZOLI_0352
ABSAZOBR_70166
ABQABAZ39_09840
ABFAMK58_04820
ATIAL072_01895
AHUA6A40_01425
AZTTSH58p_07475
AZMDM194_01090
AZZDEW08_09660
AOZHUE56_21270
SKTIGS68_19625
SMUCJL100_006520
SROEJL101_006390
RCERC1_1051(pcs)
COADR71_943
CLWCLAC_11720
CAMCI6I65_06925
CPOYGP475_04085
YIMJ5M86_14620
SERWFY030_06860
BLUTEW640_09835
NANOG5V58_17195
NAQUENKNEFLB_02178(pcsA)
NOQLN652_16635
KFLKfla_2262
KQIF1D05_31210
GOBGobs_4045
BSDBLASA_3825
MMARMODMU_2418
AHEArch_0709
ARCAHC352_03385
APHOJTE88_03540
TPYOX956_00955
TPECHLG82_09025
AMYADJ76_08725
SOOFBF35_09375
STUCG5S47_07160
ACQAM609_01165
AOSAXE84_03120
ACTOC3V41_11495
ANEATCC27039_18730(pcs)
AIRNCTC12972_01643(pcs)
ASLANCTC11923_00295(pcs)
AVCNCTC10951_01790(pcs)
AWEJG540_01475
AREPID810_10710
ACTMHCQ94_03590
AVUBK816_03835
PSUFA1sIA56_00895
RXYRxyl_0272
RRDRradSPS_0133
RUBGBA63_00640
RMARGBA65_00790
TRATrad_0527
RBARB4506
RULUC8_52170(pcs)
RMLFF011L_37910(pcs)
RLCK227x_14550(pcs)
PLHVT85_04340(pcs)
GOGC1280_04865
LRSPX52LOC_08089
IPAIsop_1798
SACISinac_5705
PBORBSF38_02387(pcs)
AGVOJF2_26750(pcs)
BBUBB_0249
BBZBbuZS7_0254
BBNBbuN40_0249
BBJBbuJD1_0249
BBURL144_01225
BGABG0251
BGBKK9_0253
BGNBgCN_0252
BGSX921_03060
BGCBLA33_03055
BAFBAPKO_0258
BAFZBafPKo_0250
BAFHBafHLJ01_0269
BAFTP612_01245
BAFEBAFK78_244
BBSBbiDN127_0247
BVTP613_01270
BCHIOY14_01225
BMAYA7X70_01235
BTUBT0249
BHRBH0249
BHIL283_01220
BDUBDU_250
BREBRE_249
BCWQ7M_252
BMOI871_01325
BMIYRJ61_01205
BPAKX966_01245
BANEN187_01185
BTURDB313_01280
BMATDB723_01220
BCOIbcCo53_000246
BPURbpuSUM_000247
ABACLuPra_05619(pcs)
SRUSRU_0340
SRMSRM_00419(pssA)
MOXDAMO_0834
 » show all
Reference
1  [PMID:10391951]
  Authors
de Rudder KE, Sohlenkamp C, Geiger O.
  Title
Plant-exuded choline is used for rhizobial membrane lipid biosynthesis by phosphatidylcholine synthase.
  Journal
J Biol Chem 274:20011-6 (1999)
DOI:10.1074/jbc.274.28.20011
  Sequence
[sme:SMc00247]
Reference
2  [PMID:10858449]
  Authors
Sohlenkamp C, de Rudder KE, Rohrs V, Lopez-Lara IM, Geiger O
  Title
Cloning and characterization of the gene for phosphatidylcholine synthase.
  Journal
J Biol Chem 275:18919-25 (2000)
DOI:10.1074/jbc.M000844200
  Sequence
[sme:SMc00247]
Other DBs
ExplorEnz - The Enzyme Database: 2.7.8.24
IUBMB Enzyme Nomenclature: 2.7.8.24
ExPASy - ENZYME nomenclature database: 2.7.8.24
BRENDA, the Enzyme Database: 2.7.8.24
CAS: 243666-86-6

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