KEGG ENZYME: 2.7.8.28

ENZYME: 2.7.8.28

Entry

EC 2.7.8.28                 Enzyme

Name

2-phospho-L-lactate transferase;
cofD (gene name);
fbiA (gene name);
LPPG:Fo 2-phospho-L-lactate transferase;
LPPG:7,8-didemethyl-8-hydroxy-5-deazariboflavin 2-phospho-L-lactate transferase;
lactyl-2-diphospho-(5')guanosine:Fo 2-phospho-L-lactate transferase

Class

Transferases;
Transferring phosphorus-containing groups;
Transferases for other substituted phosphate groups

Sysname

(2S)-lactyl-2-diphospho-5'-guanosine:7,8-didemethyl-8-hydroxy-5-deazariboflavin 2-phospho-L-lactate transferase

Reaction(IUBMB)

(1) (2S)-lactyl-2-diphospho-5'-guanosine + 7,8-didemethyl-8-hydroxy-5-deazariboflavin = GMP + factor 420-0 [RN:R09398];
(2) enolpyruvoyl-2-diphospho-5'-guanosine + 7,8-didemethyl-8-hydroxy-5-deazariboflavin = GMP + dehydro factor 420-0 [RN:R12648];
(3) 3-[(R)-glyceryl]-diphospho-5'-guanosine + 7,8-didemethyl-8-hydroxy-5-deazariboflavin = GMP + 3PG-factor 420-0 [RN:R12649]

Reaction(KEGG)

R09398 R12648 R12649

Substrate

(2S)-lactyl-2-diphospho-5'-guanosine [CPD:C19155];
7,8-didemethyl-8-hydroxy-5-deazariboflavin [CPD:C19154];
enolpyruvoyl-2-diphospho-5'-guanosine [CPD:C22297];
3-[(R)-glyceryl]-diphospho-5'-guanosine [CPD:C22298]

Product

GMP [CPD:C00144];
factor 420-0 [CPD:C19153];
dehydro factor 420-0 [CPD:C22277];
3PG-factor 420-0 [CPD:C22299]

Comment

This enzyme is involved in the biosynthesis of factor 420, a redox-active cofactor, in methanogenic archaea and certain bacteria. The specific reaction catalysed in vivo is determined by the availability of substrate, which in turn is determined by the enzyme present in the organism - EC 2.7.7.68, 2-phospho-L-lactate guanylyltransferase, EC 2.7.7.105, phosphoenolpyruvate guanylyltransferase, or EC 2.7.7.106, 3-phospho-D-glycerate guanylyltransferase.

History

EC 2.7.8.28 created 2010, modified 2020

Pathway

ec00680

Methane metabolism

ec01100

Metabolic pathways

ec01120

Microbial metabolism in diverse environments

Orthology

K11212

LPPG:FO 2-phospho-L-lactate transferase

Genes

VAQ:	FIV01_04145(cofD)

PPHA:

BVH74_17765

CPS:	CPS_4047(cofD)

ALT:	ambt_18400

AAL:	EP13_00570

ASP:	AOR13_3370

ASQ:	AVL57_01935

AAW:	AVL56_00745

ALE:	AV939_00750

ALZ:	AV940_00750

SNAN:

I6N98_10725

ZAL:	AZF00_12045

OSG:	BST96_15200

MAGA:

Mag101_11135

HJA:	BST95_09650

HALC:

EY643_13160

KIM:	G3T16_02860

MPC:	Mar181_0280

MPRI:

MP3633_0354(cofD)

MFOI:

JSY38_07520

MRHI:

KDW99_18325

MARS:

A8C75_03575

MRZ:	KDW95_12770

SDF:	ACG33_05470

BPY:	Bphyt_4253

PSPW:

BJG93_33620(cofD)

BRH:	RBRH_02552

PUD:	G9Q38_02360

DOE:	DENOEST_3711(cofD)

EBA:

p2A344

AZD:	CDA09_09445

THU:	AC731_008655

TAK:	Tharo_0192

MESP:

C1M53_21075

SMEG:

C770_GR4pC0059

SMER:

DU99_18230

ARUI:

G6M88_23520

KAI:

K32_16290

BIC:	LMTR13_24640

BRK:	CWS35_20190

BQB:	J4P68_0009790(cofD)

RPB:

RPB_4407

OCA:	OCAR_5005(cofD)

OCG:	OCA5_c29530(cofD)

SNO:

Snov_4232

STAR:

G3545_06900

LNE:	FZC33_07440

APRA:

G3A50_17780

MOG:	MMB17_16630(cofD)

HMC:	HYPMC_3549

METG:

HT051_05400 HT051_12620

NTD:	EGO55_02480

CAEN:

K5X80_05810(cofD)

RBM:

TEF_10860

PSF:

PSE_2791

CAUL:

KCG34_11235

PZU:

PHZ_c2538

LMD:	METH_04445

LAQU:

R2C4_00570

LCAE:

K3721_20515(cofD)

PDE:

Pden_1116

RMB:	K529_001415

THAS:

C6Y53_09635

NPN:	JI59_17705

NRE:	BES08_02710 BES08_26375

NOV:	TQ38_007745

SPHO:

C3E99_13155

SPHU:

SPPYR_1433(cofD)

SWI:

Swit_0414

SPHD:

HY78_26025

RDI:	CMV14_13680

SPHM:

G432_18315

SPKC:

KC8_00655

SBIN:

SBA_ch2_1010

SNAP:

PQ455_18150(cofD)

SCH:	Sphch_2203

SYB:	TZ53_04410

SBD:	ATN00_13425

SPMI:

K663_16405

SPHB:

EP837_01487(cofD)

SPHT:

K426_20935

SHYD:

CJD35_15475

SYA:	A6768_05855

SCLO:

SCLO_1006400

SUFL:

FIL70_15530

SBAR:

H5V43_13880

SPPH:

KFK14_07110

BLAS:

BSY18_2468(cofD)

SPHJ:

BSL82_04910 BSL82_08905

CMAN:

A9D14_14815

KHA:	IFJ82_10835

PAUU:

E8A73_035580(cofD)

HOH:

Hoch_0060

MTU:	Rv3261(fbiA)

MTV:

RVBD_3261

MTC:

MT3359

MRA:	MRA_3302(fbiA)

MTF:	TBFG_13290

MTB:	TBMG_03309

MTK:	TBSG_03332

MTZ:	TBXG_003289

MTI:	MRGA423_20435

MTE:	CCDC5079_3009

MTUR:

CFBS_3450(fbiA)

MTL:	CCDC5180_2972

MTO:	MTCTRI2_3328(fbiA)

MTD:	UDA_3261(fbiA)

MTN:	ERDMAN_3575(fbiA)

MTJ:	J112_17520

MTUB:

MT7199_3303

MTUE:

J114_17480

MTX:	M943_16845

MTUL:

TBHG_03197

MTUT:

HKBT1_3437(fbiA)

MTUU:

HKBT2_3444(fbiA)

MTQ:	HKBS1_3447(fbiA)

MBO:	BQ2027_MB3289(fbiA)

MBB:	BCG_3290(fbiA)

MBT:	JTY_3286(fbiA)

MBM:	BCGMEX_3288(cofD)

MBK:	K60_033900

MBX:

BCGT_3128

MAF:	MAF_32720(fbiA)

MMIC:

RN08_3596

MCE:	MCAN_32801(fbiA)

MCQ:	BN44_70046(cofD)

MCV:	BN43_60271(cofD)

MCX:	BN42_41312(cofD)

MCZ:	BN45_60291(cofD)

MLE:

ML0759

MLB:

MLBr00759

MPA:

MAP_3374

MAO:

MAP4_0408

MAVI:

RC58_01950

MAVU:

RE97_01960

MAV:	MAV_4224(cofD)

MIT:

OCO_40830

MIA:

OCU_40740

MID:

MIP_06148

MYO:

OEM_41090

MCHI:

AN480_21440

MIR:

OCQ_42100

MMAL:

CKJ54_19475

MLP:

MLM_3383

MMAN:

MMAN_28870(cofD)

MSA:	Mycsm_01371

MUL:	MUL_2606(fbiA)

MMI:	MMAR_1281(fbiA)

MMAE:

MMARE11_12470(fbiA)

MLI:	MULP_01442(fbiA)

MPSE:

MPSD_14590(cofD)

MSHO:

MSHO_60290(cofD)

MMC:

Mmcs_1324

MKM:

Mkms_1341

MJL:

Mjls_1360

MMM:

W7S_20385

MKN:	MKAN_21200

MYV:	G155_09335

MYE:	AB431_07860

MHAD:

B586_17490

MDX:	BTO20_26030

MSHG:

MSG_01181(cofD)

MFJ:	MFLOJ_22070(cofD)

MSTO:

MSTO_25780(cofD)

MSIM:

MSIM_13080(cofD)

MSAK:

MSAS_48340(cofD)

MKU:	I2456_06475

MLW:	MJO58_06220(cofD)

MGRO:

FZ046_13190

MXE:	MYXE_37090(cofD)

MNV:	MNVI_28180(cofD)

MPAG:

C0J29_07135

MNM:	MNVM_30590(cofD)

MGOR:

H0P51_06360 H0P51_22655

MCOO:

MCOO_44640(cofD)

MBAI:

MB901379_01172

MSEO:

MSEO_51130(cofD)

MHEK:

JMUB5695_03654(cofD)

MGAU:

MGALJ_57760(cofD)

MLJ:	MLAC_04500(cofD)

MBRD:

MBRA_03610(cofD)

MSHJ:

MSHI_24900(cofD)

MMAM:

K3U93_05775(cofD)

MSPG:

F6B93_05485

MOT:	LTS72_18965(cofD)

MLM:	MLPF_1195(cofD)

MPAA:

MKK62_18620(cofD)

MMEH:

M5I08_09060(cofD)

MSM:	MSMEG_1830(cofD)

MSG:	MSMEI_1787(cofD)

MSB:	LJ00_09125

MSN:	LI99_09125

MSH:	LI98_09125

MVA:

Mvan_1733

MGI:

Mflv_4730

MSP:	Mspyr1_40640

MCB:	Mycch_1342

MNE:	D174_08425

MYN:	MyAD_08280

MFT:	XA26_18670

MPHL:

MPHLCCUG_01627(cofD)

MVQ:	MYVA_1477(cofD)

MLL:	B1R94_21305

MRH:	MycrhN_0422

MTHN:

4412656_01187(cofD)

MHAS:

MHAS_00504(cofD)

MDU:	MDUV_28070(cofD)

MCHT:

MCHIJ_50200(cofD)

MDR:	MDOR_09070(cofD)

MAUU:

NCTC10437_01440

MMAG:

MMAD_14830(cofD)

MMOR:

MMOR_51210(cofD)

MFX:	MFAL_19170(cofD)

MAIC:

MAIC_13040(cofD)

MIJ:	MINS_15980(cofD)

MALV:

MALV_19530(cofD)

MTY:	MTOK_35140(cofD)

MPSC:

MPSYJ_49680(cofD)

MARZ:

MARA_24290(cofD)

MGAD:

MGAD_25250(cofD)

MHEV:

MHEL_36240(cofD)

MSAR:

MSAR_04240(cofD)

MANY:

MANY_52690(cofD)

MAUB:

MAUB_17090(cofD)

MPOF:

MPOR_20180(cofD)

MPHU:

MPHO_54240(cofD)

MMUC:

C1S78_020460

MMAT:

MMAGJ_47590(cofD)

MBOK:

MBOE_56000(cofD)

MFG:	K6L26_23195(cofD)

MSEI:

MSEDJ_27370(cofD)

MFLV:

NCTC10271_03863

MCEE:

MCEL_20340(cofD)

MBRM:

L2Z93_003006(cofD)

MMON:

EWR22_07040

MGO:	AFA91_29760

MHOL:

K3U96_19385(cofD)

MSEN:

K3U95_20440(cofD)

MPAE:

K0O64_07425(cofD)

MRF:	MJO55_07470(cofD)

MDF:	K0O62_07965(cofD)

MCRO:

MI149_08405(cofD)

MKR:	MKOR_20210(cofD)

MPAK:

MIU77_13975(cofD)

MAB:

MAB_3607

MMV:	MYCMA_05825

MABB:

MASS_3614

MABL:

MMASJCM_3604

MCHE:

BB28_18450

MIZ:	BAB75_20515

MSTE:

MSTE_03739(cofD)

MSAO:

MYCSP_16595

MSAL:

DSM43276_03405(cofD)

MJD:	JDM601_3010(fbiA)

MTER:

4434518_02997(fbiA)

MMIN:

MMIN_07410(cofD)

MHIB:

MHIB_24540(cofD)

MHER:

K3U94_17035(cofD)

MVM:	MJO54_17055(cofD)

ASD:	AS9A_3810(fbiA)

NFA:

NFA_46210

NFR:	ERS450000_05307

NBR:	O3I_035160

NNO:	NONO_c63250(cofD)

NSL:	BOX37_24640

NSR:	NS506_02072(cofD)

NTP:	CRH09_32620

NOZ:	DMB37_13820

NOD:	FOH10_03600

NAH:	F5544_37075

NAD:	NCTC11293_05925

NWL:	NWFMUON74_13460(cofD)

NIE:	KV110_34195(cofD)

NTC:	KHQ06_12815

NHU:	H0264_12270

NYA:	LTV02_20670(cofD)

NGP:	LTT66_19770(cofD)

RHA:	RHA1_ro06312

RER:	RER_21530(fbiA)

REY:

O5Y_10285

REB:	XU06_10510

RQI:	C1M55_10950

ROP:	ROP_63740(fbiA)

ROA:	Pd630_LPD02976

RPY:	Y013_07655

RBY:	CEJ39_18575

RHB:

NY08_1683

RAV:	AAT18_17230

RFA:	A3L23_00047(cofD)

RHS:	A3Q41_03366(cofD)

RHW:	BFN03_04465

RRZ:	CS378_06785

RHU:	A3Q40_02034(cofD)

RHQ:	IM25_21970

RHOD:

AOT96_21130

RRT:	4535765_03351(fbiA)

RCR:	NCTC10994_03906

RTM:	G4H71_17765

RKO:	JWS14_25815 JWS14_34325

RGO:	KYT97_07795(cofD)

ROZ:	CBI38_19200

RPSK:

JWS13_09595

RGOR:

NMQ04_14465(cofD)

REQ:

REQ_33510

GBR:

Gbro_3302

GPO:	GPOL_c30980(cofD)

GOR:

KTR9_3342

GOQ:	ACH46_06015

GTA:	BCM27_16970

GOC:	CXX93_08505

GIT:	C6V83_14655

GRU:	GCWB2_17190(cofD)

GOM:	D7316_05387(cofD)

GAV:	C5O27_11010

GOD:	GKZ92_16070

GAM:	GII34_16025

GPD:	GII33_15465

GJI:	H1R19_16010

GOI:	LK459_17880(cofD)

GHN:	MVF96_16435(cofD)

GAMI:

IHQ52_19975(cofD)

GMG:	NWF22_01500(cofD)

TPR:

Tpau_1183

TSM:	ASU32_06665

TPUL:

TPB0596_34390(cofD)

SRT:

Srot_2670

DTM:	BJL86_1020

DIT:	C3V38_10630

DIZ:	CT688_04540

DPC:	A6048_04615

DLU:	A6035_04850

DKN:	NHB83_04370

SCO:	SCO3036(SCE34.17)

SALB:

XNR_1923

SMA:	SAVERM_5040(cofD)

SGR:

SGR_4501

SGB:

WQO_13015

SCB:	SCAB_55061(cofD)

SSX:	SACTE_2502

SVL:	Strvi_8422

SHY:

SHJG_4503

SHO:	SHJGH_4266

SRC:	M271_29480

SMAL:

SMALA_3141

SSOI:

I1A49_19500

SFA:

Sfla_3871

SBH:

SBI_04465

SVE:

SVEN_2778

SDV:	BN159_5256(cofD)

SALS:

SLNWT_2576

STRP:

F750_2861

SFI:

SFUL_2632

SCI:	B446_15765

SLV:	SLIV_22515(cofD)

SGU:	SGLAU_13800(cofD)

SVT:	SVTN_14810

STRE:

GZL_05425

SCW:	TU94_13260

SLD:

T261_5068

SLC:	SL103_04170

SXI:	SXIM_18230

STRM:

M444_14300

STRC:

AA958_11400

SAMB:

SAM23877_3078(cofD)

SPRI:

SPRI_4521

SCZ:	ABE83_22880

SCX:	AS200_27270

SRW:	TUE45_04629(cofD)

STRF:

ASR50_20140

SLE:	sle_42450(sle_42450)

SRN:	A4G23_02039(cofD)

SPAV:

Spa2297_13145

STRT:

A8713_12280

SCLF:

BB341_17715

SGS:	AVL59_42920

STSI:

A4E84_15950

SKY:	D0C37_11380

SALW:

CP975_13850

SGM:	GCM10017557_50180(cofD)

SCAD:

DN051_23470

SPHW:

NFX46_36010(cofD)

SLS:	SLINC_3442

SNR:	SNOUR_25330(cofD)

SALU:

DC74_3465

SALL:

SAZ_18450

SPLU:

LK06_011880

STRD:

NI25_23610

SNW:	BBN63_21605

SAUO:

BV401_19195

SSIA:

A7J05_21725

SVU:	B1H20_12295

SPUN:

BFF78_25300

SGV:	B1H19_16740

SLAU:

SLA_2759

SALF:

SMD44_03376(cofD)

SALJ:

SMD11_4189(cofD)

SLX:	SLAV_22860(cofD)

STRO:

STRMOE7_15720

SFK:

KY5_3201

SNZ:	DC008_13670

SGE:	DWG14_05054(cofD)

SRJ:

SRO_4453

SLK:	SLUN_15500

SDX:	C4B68_24090

SGD:	ELQ87_23320

SQZ:	FQU76_11440

SCYA:

EJ357_18275

SAST:

CD934_20165

SNQ:	CP978_14100

STIR:

DDW44_10215

SKA:	CP970_26370

SGZ:	C0216_27100

SVN:	CP980_20520

SNK:	CP967_21065

SHAW:

CEB94_16540

SRK:	FGW37_12635

SFIC:

EIZ62_20210

SGAL:

CP966_14460

SSPO:

DDQ41_08705

SVR:	CP971_20720

SPAD:

DVK44_11195

SFY:	GFH48_24390

SAQU:

EJC51_20730

SGF:	HEP81_04780

SCAV:

CVT27_11710

SSEO:

D0Z67_11255

SBY:	H7H31_22370

SRIM:

CP984_24930

SSUB:

CP968_20300

SPHV:

F9278_18575

SCIN:

CP977_13485

SFUG:

CNQ36_13860

SPAC:

B1H29_22325

STSU:

B7R87_11090

SCHA:

CP983_26050

SGX:	H4W23_16030

SCOE:

CP976_17675

SBAT:

G4Z16_21470

SSPB:

CP982_17985

SNF:	JYK04_03613(cofD)

SPLA:

CP981_15390

SBRO:

GQF42_18830

STUI:

GCM10017668_27340(cofD)

SATA:

C5746_16550

SCHF:

IPT68_14685

SHUN:

DWB77_04647(cofD)

SHAR:

HUT13_11495

SCYG:

S1361_16335(cofD)

SFEU:

IM697_05855

SLIA:

HA039_21545

SDW:	K7C20_14505(cofD)

SVD:	CP969_16335

SCAL:

I6J39_12565

SAUH:

SU9_012970

SFB:	CP974_11280

SMOB:

J7W19_12335

SPRA:

CP972_14535

SPEU:

CGZ69_13685

SROI:

IAG44_24885

SXN:	IAG42_21215

SGJ:	IAG43_12130

SHK:	J2N69_14065(cofD)

SANU:

K7396_22170(cofD)

SDD:	D9753_21325

SACT:

DMT42_15900

SMAO:

CAG99_17350

SGOB:

test1122_08555(cofD)

SINE:

KI385_18460(cofD)

SLF:	JEQ17_28340

SDEC:

L3078_18485(cofD)

SAOV:

G3H79_22490

SDUR:

M4V62_25485(cofD)

SYAN:

NRK68_13430(cofD)

SRUG:

F0345_18625

SAKB:

K1J60_26680(cofD)

STAA:

LDH80_24410(cofD)

SNIG:

HEK616_03470(cofD)

SVIO:

HWN34_10305

SCT:	SCAT_2043(cofD)

SCY:	SCATT_20250

KSK:	KSE_29430(fbiA)

KAB:	B7C62_12010

KAU:	B6264_15385

KIT:	CFP65_2739

KIS:	HUT16_12690

STRI:

C7M71_010635

YIA:	LO772_21670(cofD)

STRH:

GXP74_06015

ABRY:

NYE86_05090(cofD)

LXL:	KDY119_01330(cofD)

PSIC:

J4E96_05905

MTS:

MTES_1873

MCW:	A8L33_02355

MIH:	BJP65_10325

MLV:	CVS47_03060(cofD)

MWA:	E4K62_17135(cofD)

MPRT:

ET475_03960(cofD)

MSED:

E3O41_07825(cofD)

MSF:	IT882_16035(cofD)

MCAW:

F6J84_13730(cofD)

MLZ:	F6J85_16155(cofD)

MBIN:

LXM64_14510(cofD)

MTEC:

OAU46_00540(cofD)

RTX:	TI83_05460

RTC:	APU90_01015

RTN:	A6122_1538

RRY:	C1O28_07045

RIA:	C7V51_05515

RFS:	C1I64_04310

RTE:	GSU10_08575

AGY:	ATC03_18350

AGM:	DCE93_13635

AGF:	ET445_04955

AMAU:

DSM26151_27910(fbiA)

ASOI:

MTP13_06345(cofD)

CART:

PA27867_3302

CPHY:

B5808_11950

HUM:	DVJ78_09000

HUW:	FPZ11_07335

GRY:	D7I44_06895

LARI:

KI794_01700(cofD)

MANT:

BHD05_14670

HEA:	HL652_10800

HEH:	L3i23_06180(cofD)

GLN:	F1C58_11305

CHRE:

IE160_09575(cofD)

AGX:	AGREI_1001(fbiA)

SUBT:

KPL76_08075

SUBA:

LQ955_10135(cofD)

HOM:	OF852_06365(cofD)

DAY:	FV141_09350

DERM:

H7F30_07875

LMOI:

VV02_10695

YIM:	J5M86_04320

ALX:	LVQ62_16225(cofD)

XCE:

Xcel_3009

XYL:	ET495_10985

XYA:	ET471_03440

IVA:	Isova_2671

IDO:	I598_2998(cofD)

CET:	B8281_07125

CCEU:

CBR64_04235

CPRT:

FIC82_005740

SKE:	Sked_24050

CFI:

Celf_1450

CGA:	Celgi_2151

CEJ:	GC089_11365

CELH:

GXP71_04070

CIRA:

LFM56_11085(cofD)

CELC:

K5O09_06690(cofD)

CFEN:

KG102_06220

OEK:	FFI11_000580

ICA:	Intca_2520

ARS:	ADJ73_09015

JTE:	ASJ30_11180 ASJ30_13400

JLI:	EXU32_03175

JME:	EEW87_003975

JAY:	H7A72_11415

TEH:	GKE56_00815

PEI:	H9L10_02750

SERJ:

SGUI_1033

SERW:

FY030_04075

ORN:	DV701_06625

ORZ:	FNH13_13675

BRI:	FDF13_08045

AUS:	IPK37_14460(cofD)

GYU:	FE374_01130

MPH:	MLP_39300(cofD)

MIK:	FOE78_07435

MICG:

GJV80_00180

NCA:

Noca_1410

NDK:	I601_0152(cofD)

NOY:	EXE57_06555

NOI:	FCL41_12290

NOO:	FE634_07295

NDP:	E2C04_12860

NBE:	Back2_26820(cofD)

NANO:

G5V58_15765

NMES:

H9L09_04150

NARO:

CFH99_18250

NPI:	G7071_09230

NAQU:

ENKNEFLB_03314(cofD)

NRO:	K8W59_12195(cofD)

NOQ:	LN652_18835(cofD)

NCQ:	K6T13_04835(cofD)

NPC:	KUV85_01620(cofD)

NPS:	KRR39_14595(cofD)

PSIM:

KR76_19800

AEZ:	C3E78_12880

AEB:	C6I20_11375

AEF:	GEV26_02940 GEV26_12935

MUZ:	H4N58_15560

NBT:	KLP28_10510

KFL:

Kfla_1587

KQI:	F1D05_27420

TFU:

Tfu_2517

THAO:

NI17_015395

TALX:

FOF52_12865

NDA:

Ndas_3767

NAL:	B005_0945(cofD)

NGV:	CDO52_24245

NEX:	NE857_28260(cofD)

NEC:	KGD82_04620

STRR:

EKD16_04585(cofD)

SNAH:

OUQ99_05240(cofD)

SAIU:

J4H86_12275

TCU:

Tcur_4072

ACTW:

F7P10_11795

AGRA:

AGRA3207_002958

SRO:

Sros_1380

NOA:	BKM31_38770

NOW:	GBF35_06600

NCX:	Nocox_05955(cofD)

NGN:	LCN96_06645(cofD)

TBI:

Tbis_0749

FRA:	Francci3_0742

FRE:	Franean1_5868

FRI:	FraEuI1c_6071

FAL:

FRAAL1260

FSY:	FsymDg_1077

ACE:

Acel_0455

NML:

Namu_4175

NAK:	EH165_10585

GOB:

Gobs_4304

BSD:	BLASA_4121(cofD)

BLAP:

MVA48_20180(cofD)

MMAR:

MODMU_4702(cofD)

KRA:

Krad_3851

SEN:

SACE_6466

SACG:

FDZ84_07205

SVI:	Svir_06240

SACC:

EYD13_03500(cofD)

AMD:	AMED_1023(cofD)

AMN:

RAM_05205

AMM:	AMES_1019(cofD)

AMZ:	B737_1020(cofD)

AOI:	AORI_1010(cofD)

AJA:	AJAP_34530(cofD)

AMQ:	AMETH_0932(cofD)

AMYC:

CU254_03585

AMYB:

BKN51_39155

AAB:	A4R43_35500

AMYY:

YIM_42555(cofD)

AORI:

SD37_36140

AACD:

LWP59_04475(cofD)

APRT:

MUY14_31680(cofD)

AROO:

NQK81_17830(cofD)

ATHM:

L1857_07280(cofD)

PDX:	Psed_1331 Psed_5208

PSEA:

WY02_11520

PSEE:

FRP1_02690

PSEH:

XF36_02095

PSEQ:

AD006_10305

PECQ:

AD017_18135

PHH:	AFB00_16165

PAUT:

Pdca_56450(cofD)

PBRO:

HOP40_13550

PPEL:

H6H00_13215

APRE:

CNX65_31165

AMI:

Amir_6333

SESP:

BN6_76240

SSYI:

EKG83_42415

KAL:

KALB_7913

KPHY:

AOZ06_48150

LED:	BBK82_19185

AHM:	TL08_23380

ACTI:

UA75_27200

ACAD:

UA74_26610

AHG:	AHOG_24530(cofD)

ACTA:

C1701_14680

ALO:

CRK59728

PMAD:

BAY61_03995

SACE:

GIY23_18805

ACTU:

Actkin_05519

STP:	Strop_0944

SAQ:

Sare_0886

MAU:	Micau_0952

MIL:

ML5_1200

MICB:

MicB006_0998

MTUA:

CSH63_19730

MICH:

FJK98_05050

MTEM:

GCE86_30270

MCAB:

HXZ27_05700

MSAG:

GCM10017556_35210(cofD)

VMA:	VAB18032_09465

MCRA:

ID554_08065

VER:	HUT12_05625

MENO:

Jiend_19040(cofD)

ASE:	ACPL_1048(fbiA)

AMS:

AMIS_8540

ACTN:

L083_1151(fbiA)

AFS:

AFR_05650

ACTS:

ACWT_0930

AIH:	Aiant_52210(cofD)

ACTR:

Asp14428_35950(cofD)

PLK:	CIK06_05190

PLAB:

C6361_20385

PLAT:

C6W10_23375

PFLA:

Pflav_062080(cofD)

PSUU:

Psuf_024020(cofD)

ATL:	Athai_49510(cofD)

ASER:

Asera_25010(cofD)

PRY:	Prubr_13810(cofD)

CATI:

CS0771_04610(cofD)

DFU:	Dfulv_43310(cofD)

DROS:

Drose_33160

DAUR:

Daura_46965

NHY:	JQS43_20530

CCAZ:

COUCH_33980(cofD)

CAI:

Caci_7611

AEY:	CDG81_04210

EKE:	EK0264_15480

JTL:	M6D93_14715(cofD)

ABAI:

IMCC26256_111646

RXY:

Rxyl_0958

RRD:	RradSPS_0868

RMAR:

GBA65_08890

BSOL:

FSW04_11720

CWO:

Cwoe_4149

PARN:

NBH00_07370(cofD)

SBAE:

DSM104329_01287(fbiA_1) DSM104329_01863(fbiA_2)

TALU:

JDY09_03405(cofD)

AFO:

Afer_0741

AYM:	YM304_28610(fbiA)

ATQ:	GH723_12310

AQZ:	KSP35_00880(cofD)

IAM:	HC251_16060

IMA:	PO878_14425(cofD)

ERZ:	ER308_14060

EUZ:	DVS28_a4425

RRS:	RoseRS_1138

RCA:

Rcas_3979

CAU:

Caur_0204

CHL:	Chy400_0218

CAG:

Cagg_0665

ATM:

ANT_14430

ABAT:

CFX1CAM_1027(cofD)

PSUB:

Pelsub_P1766

LEK:	hrd7_26920

CAP:	CLDAP_12760(cofD)

PBF:	CFX0092_A2821(cofD)

KBS:	EPA93_18910

TBH:	Tbon_06685

THUG:

KNN16_07965

TTR:

Tter_1864

PMET:

G4Y79_17600

TRO:	trd_A0801(cofD)

STI:

Sthe_2613

MJA:

MJ_1256

MFE:	Mefer_0031

MVU:	Metvu_0809

MFS:	MFS40622_0677

MIF:	Metin_0575

MJH:	JH146_0469

MESG:

MLAUSG7_1279(cofD)

MESA:

MLASG1_0497(cofD)

MIG:	Metig_1491

MMP:	MMP0404(cofD)

MMQ:	MmarC5_1234

MMX:	MmarC6_0506

MMZ:	MmarC7_1402

MMD:

GYY_02090

MMAK:

MMKA1_04230(cofD)

MMAO:

MMOS7_04190(cofD)

MMAD:

MMJJ_06330(cofD)

MAE:

Maeo_0819

MVN:	Mevan_1392

MVO:

Mvol_1651

MOK:	Metok_0351

METF:

CFE53_04155

MTH:

MTH_1018

MMG:	MTBMA_c14000(cofD)

MWO:	MWSIV6_1404(cofD)

MTEE:

MTTB_04060

METC:

MTCT_0926

METE:

tca_00979(cofD)

METZ:

METMT2_1044

METK:

FVF72_06520

MTHM:

FZP57_06710

METJ:

FZP68_03950

MST:	Msp_1403(cofD)

METB:

AW729_08505

MRU:	mru_1844(cofD)

MSI:

Msm_0974

MEB:	Abm4_1487(cofD)

MMIL:

sm9_1937(cofD)

MEYE:

TL18_09140

MOL:

YLM1_1301

MARO:

MarbSA_16660

METV:

K4897_06605(cofD)

MEL:	Metbo_2436

MEW:	MSWAN_0206

METH:

MBMB1_0200(cofD)

MFC:	BRM9_2100(cofD)

MFI:	DSM1535_1581(cofD)

MCUB:

MCBB_0215(cofD)

MSUB:

BK009_10795

METN:

BK008_06435

METT:

CIT01_02830

METO:

CIT02_06015

MEME:

HYG87_04415

MFV:

Mfer_0319

MKA:

MK1489

AFU:

AF_0917

AFG:	AFULGI_00010030

APO:	Arcpr_1471

AVE:	Arcve_0317

AST:	Asulf_01226

FPL:

Ferp_0960

GAC:

GACE_1169

GAH:

GAH_01892

MBA:	Mbar_A1631

MBY:	MSBRM_0533

MBW:	MSBRW_3100

MBAR:

MSBR2_1845

MBAK:

MSBR3_1916

MAC:

MA_0714

MMA:

MM_1874

MMAZ:

MmTuc01_1948

MMJ:	MSMAS_2813

MMAC:

MSMAC_1625

MVC:	MSVAZ_2561

MEK:	MSKOL_2569

MLS:	MSLAZ_0397

METM:

MSMTP_2712

MEF:	MSWH1_0464

MEQ:	MSWHS_0475

MSJ:	MSSAC_0660

MSZ:	MSSIH_0603

MSW:	MSSIT_0634

MTHR:

MSTHT_1404

MTHE:

MSTHC_1885

MHOR:

MSHOH_3512

MFZ:	AOB57_005975

MBU:

Mbur_1411

MMET:

MCMEM_1896

MELO:

J7W08_08440

MMH:

Mmah_1721

MHAZ:

BHR79_05100

MEV:	Metev_0504

MZH:	Mzhil_1840

MPY:

Mpsy_2105

MZI:	HWN40_11685

MHZ:	Metho_2233

MTP:

Mthe_1438

MCJ:	MCON_1062(cofD)

MHI:

Mhar_0950

MHU:

Mhun_2444

MRTJ:

KHC33_16865

MLA:

Mlab_0152

MEM:	Memar_2144 Memar_2145

MBG:	BN140_1350(cofD1) BN140_1351(cofD2)

MEMA:

MMAB1_1720(cofD) MMAB1_1721

MCHK:

MchiMG62_24560 MchiMG62_24570

MSUM:

OH143_05005 OH143_05010(cofD)

MPI:	Mpet_1887 Mpet_1889

MEND:

L6E24_01005(cofD)

MAQE:

RJ40_06725

MOU:	OU421_09600(cofD)

MBN:

Mboo_0117

MFO:	Metfor_0245

MPL:

Mpal_2578

MPD:	MCP_1915(cofD)

MEZ:	Mtc_1637(cofD)

RCI:	RRC453(cofD)

HAL:

VNG_1429C

HSL:	OE_3057F(cofD)

HDL:	HALDL1_12565

HHB:	Hhub_2871(cofD)

HAGS:

JT689_07140

HABO:

JRZ79_05575(cofD)

HNO:	LT974_11120(cofD)

HLU:	LT972_03675(cofD)

HANR:

LJ422_05825(cofD)

HJE:	HacjB3_07015

HALH:

HTSR_0535

HHSR:

HSR6_0519

HSU:	HLASF_1691

HSF:	HLASA_1678

SALR:

FQU85_12630

HALR:

EFA46_000610

HAAD:

MW046_04935(cofD)

HALX:

M0R89_00415(cofD)

HAXZ:

M0R88_00425(cofD)

SALI:

L593_00185

SAIM:

K0C01_03595(cofD)

HARA:

AArcS_1459(cofD)

HMA:

rrnAC0051

HHI:

HAH_0810

HHN:	HISP_04195

HAB:	SG26_11910

HTA:	BVU17_03985

HALJ:

G9465_13585

HSIN:

KDQ40_09460

NPH:	NP_2028A(cofD)

NMO:	Nmlp_3454(cofD)

NHO:	HWV23_03700

NSAL:

HWV07_19045

HUT:

Huta_0762

HTI:

HTIA_0655

HALA:

Hrd1104_04245

HMU:

Hmuk_2581

HALZ:

E5139_00175

HALL:

LC1Hm_1922(cofD)

HAZP:

GBQ70_00175

HALI:

BV210_16050

HSN:	DV733_11815

HDS:	HSR122_1780(cofD)

HRR:	HZS55_20720

HPEL:

HZS54_24170

HLT:	I7X12_15205

HARC:

HARCEL1_06895

HDO:	MUK72_11245(cofD)

SSAI:

N0B31_08175(cofD)

HWA:	HQ_3012A(cofD)

HWC:	Hqrw_3528(cofD)

HVO:	HVO_2479(cofD)

HME:

HFX_2485

HGI:	ABY42_12390

HALE:

G3A49_15620

HLS:	KU306_00535(cofD)

HLN:	SVXHx_2123(cofd)

HBO:	Hbor_11120

HAQ:	DU484_13470

HAJ:	DU500_13495

HAER:

DU502_10730

HRA:	EI982_01655

HLM:	DV707_05055

HALM:

FCF25_04540

HLA:

Hlac_2334

HALP:

DOS48_11785

HALB:

EKH57_13340

HEZZ:

EO776_12975

HALQ:

Hrr1229_009040

HSS:	J7656_03315

HSAI:

HPS36_08660

HAZZ:

KI388_11530

SRUB:

C2R22_11755

HAE:	halTADL_0704

HALN:

B4589_005915

HALG:

HUG10_03145

HALU:

HUG12_13710

HMP:	K6T50_01380(cofD)

HRE:	K6T36_01180(cofD)

HRM:	K6T25_00130(cofD)

HACB:

Hbl1158_08300(cofD)

HDF:	AArcSl_0948(cofD)

HAH:	Halar_1768

HTU:

Htur_1894

HSAL:

JMJ58_19920

HAKZ:

J0X25_16190(cofD)

NMG:	Nmag_0613(cofD)

HXA:	Halxa_2708

NAT:

NJ7G_0764

NPE:	Natpe_2234

NVR:	FEJ81_10100

NPL:	FGF80_01720

NAY:	HYG81_00920(cofD)

HALY:

HYG82_02660

HJT:	DVR14_19220 DVR14_23350

HLO:	J0X27_01635

NGE:	Natgr_0322

HRU:	Halru_1715

HALV:

NGM15_03890(cofD)

NOU:	Natoc_3578

HLR:	HALLA_12590

HLC:	CHINAEXTREME12800

NAJ:	B1756_01600

NAG:	AArcMg_2242

NAN:	AArc1_1444

NBG:	DV706_14510

NAS:	GCU68_14710

HDA:	BB347_05240

SAWL:

NGM29_11995(cofD)

MELU:

MTLP_06820

MEAM:

MU439_06170(cofD)

NMR:

Nmar_0626

NIR:	NSED_03225

NKR:	NKOR_03205

NID:	NPIRD3C_1641

NIN:	NADRNF5_1524(cofD)

NIW:	Nisw_01780

NCL:	C5F47_05945

NOX:	C5F49_05785

NUE:	C5F50_04635

NIP:	NsoK4_05235

NZT:	NZOSNM25_001369

NCT:	NMSP_1058(cofD)

NIC:	DSQ20_03325

CSY:	CENSYa_1217

NGA:	Ngar_c13870(cofD)

NVN:	NVIE_001510(cofD)

NEV:

NTE_01463

TAA:	NMY3_01423(cofD)

NFN:	NFRAN_2318(cofD)

NCV:

NCAV_1164

CSU:	CSUB_C1237

NBV:	T478_0979(cofD)

TAH:	SU86_003065

NIU:	DSQ19_03545

NDV:	NDEV_0695(cofD)

CCAI:

NAS2_0477

LOKI:

Lokiarch_23950(cofD_1) Lokiarch_46980(cofD_2)

» show all

Reference

1 [PMID:11888293]

Authors

Graupner M, Xu H, White RH

Title

Characterization of the 2-phospho-L-lactate transferase enzyme involved in coenzyme F(420) biosynthesis in Methanococcus jannaschii.

Journal

Biochemistry 41:3754-61 (2002)
DOI:10.1021/bi011937v

Sequence

[mja:MJ_1256]

Reference

2 [PMID:18252724]

Authors

Forouhar F, Abashidze M, Xu H, Grochowski LL, Seetharaman J, Hussain M, Kuzin A, Chen Y, Zhou W, Xiao R, Acton TB, Montelione GT, Galinier A, White RH, Tong L

Title

Molecular insights into the biosynthesis of the F420 coenzyme.

Journal

J Biol Chem 283:11832-40 (2008)
DOI:10.1074/jbc.M710352200

Sequence

[mma:MM_1874]

Reference

3 [PMID:31469543]

Authors

Braga D, Last D, Hasan M, Guo H, Leichnitz D, Uzum Z, Richter I, Schalk F, Beemelmanns C, Hertweck C, Lackner G

Title

Metabolic Pathway Rerouting in Paraburkholderia rhizoxinica Evolved Long-Overlooked Derivatives of Coenzyme F420.