KEGG   ENZYME: 2.7.8.38
Entry
EC 2.7.8.38                 Enzyme                                 
Name
archaetidylserine synthase
Class
Transferases;
Transferring phosphorus-containing groups;
Transferases for other substituted phosphate groups
Sysname
CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol:L-serine 2,3-bis-(O-geranylgeranyl)-sn-glycerol phosphotransferase
Reaction(IUBMB)
(1) CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol + L-serine = CMP + 2,3-bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine [RN:R10255];
(2) CDP-2,3-bis-(O-phytanyl)-sn-glycerol + L-serine = CMP + 2,3-bis-(O-phytanyl)-sn-glycero-1-phospho-L-serine [RN:R10441]
Reaction(KEGG)
R10255 R10441
Substrate
CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol [CPD:C18059];
L-serine [CPD:C00065];
CDP-2,3-bis-(O-phytanyl)-sn-glycerol [CPD:C20627]
Product
CMP [CPD:C00055];
2,3-bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine [CPD:C20466];
2,3-bis-(O-phytanyl)-sn-glycero-1-phospho-L-serine [CPD:C20628]
Comment
Requires Mn2+. Isolated from the archaeon Methanothermobacter thermautotrophicus.
History
EC 2.7.8.38 created 2013, modified 2013
Pathway
ec00564  Glycerophospholipid metabolism
ec01110  Biosynthesis of secondary metabolites
Orthology
K19665  archaetidylserine synthase
Genes
EPSL0Y14_09115
MJAMJ_1212
MFEMefer_0273
MVUMetvu_1372
MFSMFS40622_0843
MIFMetin_0469
MJHJH146_0624
MESGMLAUSG7_0063(pssA)
MESAMLASG1_1245(pssA)
MIGMetig_0758
MMPMMP1171(pssA)
MMQMmarC5_0416
MMXMmarC6_1500
MMZMmarC7_0419
MMDGYY_06700
MMAKMMKA1_13490(pssA)
MMAOMMOS7_12790(pssA)
MMADMMJJ_16740
MAEMaeo_1058
MVNMevan_0491
MVOMvol_0960
MOKMetok_1327
METFCFE53_05690(pssA)
MTHMTH_1027
MMGMTBMA_c14090(pssA)
MWOMWSIV6_1413
MTEEMTTB_03960
METCMTCT_0935
METEtca_00988
METZMETMT2_1053
METKFVF72_06475(pssA)
MTHMFZP57_06755(pssA)
METJFZP68_03905(pssA)
MSTMsp_1394
METBAW729_08535
MRUmru_1834(pssA)
MSIMsm_0982
MEBAbm4_1497
MMILsm9_1037(pssA)
MEYETL18_09180
MOLYLM1_1292
MAROMarbSA_17000
METVK4897_06565
MELMetbo_2427
MEWMSWAN_0215
METHMBMB1_0210
MFCBRM9_2090(pssA)
MFIDSM1535_1591
MCUBMCBB_0224
MSUBBK009_10845
METNBK008_06485
METTCIT01_02880(pssA)
METOCIT02_05970(pssA)
MEMEHYG87_04370
MKAMK0161(pssA)
AFUAF_2044
AFGAFULGI_00023120
APOArcpr_0869
AVEArcve_0399
ASTAsulf_01999
FPLFerp_1409
GACGACE_0950
GAHGAH_01927
MBAMbar_A0874
MBYMSBRM_0121
MBWMSBRW_0124
MBARMSBR2_2259
MBAKMSBR3_2310
MACMA_0116(pss)
MMAMM_1403
MMAZMmTuc01_1461
MMJMSMAS_3260
MMACMSMAC_3281
MVCMSVAZ_3392
MEKMSKOL_3352
MLSMSLAZ_3173
METMMSMTP_1929 MSMTP_3154
MEFMSWH1_3106
MEQMSWHS_3315
MSJMSSAC_0094
MSZMSSIH_0084
MSWMSSIT_0085
MTHRMSTHT_1900
MTHEMSTHC_1383
MHORMSHOH_4008
MFZAOB57_008805
MBUMbur_0786 Mbur_2198
MMETMCMEM_0374
MELOJ7W08_03755 J7W08_12000
MMHMmah_0393
MHAZBHR79_01540
MEVMetev_1119
MZHMzhil_1683
MPYMpsy_2327
MZIHWN40_10705
MHZMetho_0453
MTPMthe_1331
MCJMCON_0461(pssA)
MHIMhar_2192
HALVNG_0784G(pssA)
HSLOE_2155R(pgsA3)
HDLHALDL1_08325
HHBHhub_1848(pgsA1)
HAGSJT689_04500
HABOJRZ79_03005
HNOLT974_04195
HLULT972_08415
HANRLJ422_03225
HJEHacjB3_10815
HALHHTSR_1242(pssA)
HHSRHSR6_1314(pssA)
HSUHLASF_1159(pssA)
HSFHLASA_1147(pssA)
SALRFQU85_10535
HALREFA46_008265
HARAAArcS_2035(pssA)
HAADMW046_10585
HALXM0R89_13810
HMArrnAC0788(pssA)
HHIHAH_1434(pssA)
HHNHISP_07325
HABSG26_15170
HTABVU17_06970
HALJG9465_12530
HSINKDQ40_06320
NPHNP_3230A(assA)
NMONmlp_1867(pgsA3)
NHOHWV23_04800
NSALHWV07_04835
HUTHuta_0720
HTIHTIA_0627
HALAHrd1104_09390
HMUHmuk_2392
HALZE5139_15090
HALLLC1Hm_1749(pssA)
HAZPGBQ70_15110
HALIBV210_02670
HSNDV733_01725
HDSHSR122_1044(pssA)
HRRHZS55_15510
HPELHZS54_18560
HLTI7X12_20080
HDOMUK72_09135
HWAHQ_2356A(assA)
HWCHqrw_2603(assA)
HVOHVO_1143(assA)
HMEHFX_1155(pssA)
HGIABY42_05580
HALEG3A49_08935
HBOHbor_20980
HAQDU484_14580
HAJDU500_14610
HAERDU502_12740
HRAEI982_05010
HLMDV707_10315
HALMFCF25_12415
HLAHlac_0607
HALPDOS48_02905
HALBEKH57_08310
HEZZEO776_04185
HALQHrr1229_003130
HSSJ7656_12675
HSAIHPS36_03020
HAZZKI388_01670
SRUBC2R22_07300
HAEhalTADL_3140
HALNB4589_002185
HALGHUG10_02765
HALUHUG12_13975
HMPK6T50_00685
HREK6T36_00905
HRMK6T25_00325
HACBHbl1158_08105
HDFAArcSl_2371(pssA)
HAHHalar_1044
HTUHtur_1508
HDABB347_03740
HSALJMJ58_01155
HLOJ0X27_12315
HAKZJ0X25_14405
NMGNmag_2425(assA)
HXAHalxa_2866
NATNJ7G_3135
NPENatpe_2768
NVRFEJ81_12770
NPLFGF80_12520
NAYHYG81_16135
HALYHYG82_00155
HJTDVR14_03780
NGENatgr_0924
HRUHalru_0823
NOUNatoc_0839
SALIL593_13620
SAIMK0C01_00080
HLRHALLA_09750
HLCCHINAEXTREME16935
NAJB1756_01745
NAGAArcMg_1128
NANAArc1_2494
NBGDV706_12735
NASGCU68_13485
SAWLNGM29_16905
PDLPyrde_1316
FFOFFONT_0336
LOKILokiarch_19230 Lokiarch_20140
PSYTDSAG12_02960
 » show all
Reference
1  [PMID:12562787]
  Authors
Morii H, Koga Y
  Title
CDP-2,3-Di-O-geranylgeranyl-sn-glycerol:L-serine O-archaetidyltransferase (archaetidylserine synthase) in the methanogenic archaeon Methanothermobacter thermautotrophicus.
  Journal
J Bacteriol 185:1181-9 (2003)
DOI:10.1128/JB.185.4.1181-1189.2003
  Sequence
[mth:MTH_1027]
Other DBs
ExplorEnz - The Enzyme Database: 2.7.8.38
IUBMB Enzyme Nomenclature: 2.7.8.38
ExPASy - ENZYME nomenclature database: 2.7.8.38
BRENDA, the Enzyme Database: 2.7.8.38

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