KEGG   ENZYME: 2.7.8.40Help
Entry
EC 2.7.8.40                 Enzyme                                 

Name
UDP-N-acetylgalactosamine-undecaprenyl-phosphate N-acetylgalactosaminephosphotransferase;
WecP;
UDP-GalNAc:polyprenol-P GalNAc-1-P transferase;
UDP-GalNAc:undecaprenyl-phosphate GalNAc-1-phosphate transferase
Class
Transferases;
Transferring phosphorus-containing groups;
Transferases for other substituted phosphate groups
BRITE hierarchy
Sysname
UDP-N-acetyl-alpha-D-galactosamine:ditrans,octacis-undecaprenyl phosphate N-acetyl-D-galactosaminephosphotransferase
Reaction(IUBMB)
UDP-N-acetyl-alpha-D-galactosamine + ditrans,octacis-undecaprenyl phosphate = UMP + N-acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol [RN:R10465]
Reaction(KEGG)
Substrate
UDP-N-acetyl-alpha-D-galactosamine [CPD:C00203];
ditrans,octacis-undecaprenyl phosphate [CPD:C17556]
Product
UMP [CPD:C00105];
N-acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol [CPD:C20620]
Comment
The enzyme catalyses a step in the assembly of the repeating-unit of the O-antigen of the Gram-negative bacterium Aeromonas hydrophila AH-3. The enzyme shows no activity with UDP-N-acetyl-alpha-D-glucosamine (cf. EC 2.7.8.33, UDP-N-acetylglucosamine-undecaprenyl-phosphate N-acetylglucosaminephosphotransferase).
History
EC 2.7.8.40 created 2013
Orthology
K21303  UDP-GalNAc:undecaprenyl-phosphate GalNAc-1-phosphate transferase
Genes
MHT: D648_4350
MHQ: D650_23800
MHX: MHH_c09800
MHAE: F382_10030
MHAO: J451_10250
MHAL: N220_02125
MHAQ: WC39_11720
MHAY: VK67_11725
MVR: X781_19930
ASI: ASU2_00220
PALI: A3K91_0310
CSA: Csal_1711
HBE: BEI_1695(rfbP)
ABO: ABO_0943
ADI: B5T_01760
ACAV: VI35_13815
KKI: KKKWG1_2149(wecA)
ECOR: SAMEA4412678_0503(wcaJ)
AMIM: MIM_c06830
AFQ: AFA_16565
PHL: KKY_3136
RBM: TEF_03940
HBA: Hbal_2645
SGI: SGRAN_2366(wecA)
SWI: Swit_4813
SPHI: TS85_15175
SPHD: HY78_00615
SSY: SLG_21500
SPHT: K426_25985
BLAS: BSY18_3054
PORL: BG023_1167
LPIL: LIP_2243
DGO: DGo_CA0113(wcaJ)
LIL: LA_1647(wcaJ)
LIE: LIF_A1333(wcaJ)
LIC: LIC_12137
LIS: LIL_12271(wcaJ3)
LBJ: LBJ_1167
LBL: LBL_1221
 » show all
Taxonomy
Reference
1  [PMID:21335454]
  Authors
Merino S, Jimenez N, Molero R, Bouamama L, Regue M, Tomas JM
  Title
A UDP-HexNAc:polyprenol-P GalNAc-1-P transferase (WecP) representing a new subgroup of the enzyme family.
  Journal
J Bacteriol 193:1943-52 (2011)
DOI:10.1128/JB.01441-10
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.7.8.40
IUBMB Enzyme Nomenclature: 2.7.8.40
ExPASy - ENZYME nomenclature database: 2.7.8.40
BRENDA, the Enzyme Database: 2.7.8.40

DBGET integrated database retrieval system