KEGG   ENZYME: 2.7.8.44Help
Entry
EC 2.7.8.44                 Enzyme                                 

Name
teichoic acid glycerol-phosphate primase;
Tag primase;
CDP-glycerol:glycerophosphate glycerophosphotransferase;
tagB (gene name);
tarB (gene name)
Class
Transferases;
Transferring phosphorus-containing groups;
Transferases for other substituted phosphate groups
BRITE hierarchy
Sysname
CDP-glycerol:N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol glycerophosphotransferase
Reaction(IUBMB)
CDP-glycerol + N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol = CDP + 4-O-[(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol [RN:R11558]
Reaction(KEGG)
Substrate
CDP-glycerol [CPD:C00513];
N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol [CPD:C04881]
Product
CDP [CPD:C00112];
4-O-[(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol [CPD:C21464]
Comment
Involved in the biosynthesis of teichoic acid linkage units in bacterial cell walls. This enzyme adds the first glycerol unit to the disaccharide linker of the teichoic acid.
History
EC 2.7.8.44 created 2016
Orthology
K21285  teichoic acid glycerol-phosphate primase
Genes
CAMP: CFT03427_1565
CFP: CR44_07935 CR44_07945
SDO: SD1155_05970
BSU: BSU35760(tagB)
BSR: I33_3705
BSL: A7A1_1144
BSH: BSU6051_35760(tagB)
BSY: I653_17440
BSUT: BSUB_03809(tagB)
BSUL: BSUA_03809(tagB)
BSUS: Q433_19590
BSS: BSUW23_17560(tarB)
BST: GYO_3932(tarB)
BSO: BSNT_10220(tagB)
BSQ: B657_35760(tagB)
BSX: C663_3467(tarB)
BLI: BL02433(tagB)
BLD: BLi03820(tagB)
BLH: BaLi_c38320(tagB)
BAQ: BACAU_3319(tagB)
BYA: BANAU_3478(tagB)
BAMP: B938_16890
BAML: BAM5036_3213(tagB)
BAMA: RBAU_3429(tagB)
BAMN: BASU_3207(tagB)
BAMB: BAPNAU_3486(tagB)
BAMT: AJ82_18570
BAMY: V529_35570(tagB)
BMP: NG74_03465(tagB)
BAO: BAMF_3415(tagB)
BAZ: BAMTA208_18095(tagB)
BQL: LL3_03710(tagB)
BXH: BAXH7_03699(tagB)
BQY: MUS_3917(tagB)
BAMI: KSO_002625
BAMC: U471_34160
BAMF: U722_17635
BMYO: BG05_726
BMYC: DJ92_2373
BPU: BPUM_3232
BPUM: BW16_17250
BPUS: UP12_16740
BAG: Bcoa_0457
BJS: MY9_3629
BACW: QR42_16245
BACP: SB24_12250
BACB: OY17_00125
BACY: QF06_16285
BACL: BS34A_38890(tagB)
BALM: BsLM_3592
BGY: BGLY_4217
GEA: GARCT_03218(tagB)
AXL: AXY_20290(tagB)
VPN: A21D_00863(tagB)
SAU: SA0595(tagB)
SAV: SAV0639(tagB)
SAW: SAHV_0636(tagB)
SAM: MW0601(tagB)
SAS: SAS0605
SAR: SAR0649(tagB)
SAC: SACOL0696(tagB)
SAX: USA300HOU_0659(tagB3)
SAA: SAUSA300_0626(tagB)
SAE: NWMN_0609(tagB)
SAD: SAAV_0602(tagB)
SUE: SAOV_0674
SUJ: SAA6159_00594(tagB)
SUK: SAA6008_00656(tagB)
SUC: ECTR2_591
SUZ: MS7_0690
SUX: SAEMRSA15_05650(tagB)
SUW: SATW20_07140(tagB)
SUG: SAPIG0718
SUF: SARLGA251_05730(tagB)
SAUA: SAAG_01062
SAUE: RSAU_000595(tagB)
SAUS: SA40_0580(tagB)
SAUU: SA957_0595(tagB)
SAUG: SA268_0593(tagB)
SAUZ: SAZ172_0651(tagB)
SAUF: X998_0687
SAB: SAB0589(tagB)
SUY: SA2981_0615(tagB)
SAUB: C248_0721(tagB)
SAUM: BN843_6410
SAUC: CA347_653
SAUR: SABB_06074
SAUI: AZ30_03350
SAUD: CH52_02565
SAMS: NI36_03200
SEP: SE0413
SER: SERP0298
SEPP: SEB_00334
SEPS: DP17_1717
SHA: SH2257(tagB)
SHH: ShL2_02107(tagB)
SSP: SSP2080
SCA: SCA_0288(tagB)
SLN: SLUG_21590(tagB)
SDT: SPSE_2110(tagB)
SPAS: STP1_1725
SXO: SXYL_02210(tagB)
SHU: SHYC_10505(tagB)
SCAP: AYP1020_0008(tagB)
SSCH: LH95_10100
SSCZ: RN70_10835
SAGQ: EP23_11665
MCL: MCCL_0653
LMO: lmo1088(tagB)
LMN: LM5578_1171(tagB)
LMY: LM5923_1125(tagB)
LMOC: LMOSLCC5850_1094(tagB)
LMOE: BN418_1306
LMOB: BN419_1303
LMOD: LMON_1098(tagB)
LMOW: AX10_14020
LMOM: IJ09_04845
LMOG: BN389_11170(tagB)
LMP: MUO_05690
LMOL: LMOL312_1084(tagB)
LMOX: AX24_02840
LMQ: LMM7_1114(tagB)
LML: lmo4a_1092(tagB)
LMS: LMLG_2571
LMW: LMOSLCC2755_1086(tagB)
LMX: LMOSLCC2372_1102(tagB)
LMZ: LMOSLCC2482_1132(tagB)
LMON: LMOSLCC2376_1055(tagB)
LMOS: LMOSLCC7179_1069(tagB)
LMOO: LMOSLCC2378_1101(tagB)
LMOY: LMOSLCC2479_1102(tagB)
LMOT: LMOSLCC2540_1085(tagB)
LMOA: LMOATCC19117_1106(tagB)
LMOK: CQ02_05650
LIN: lin1075
LWE: lwe1065(tagB)
LSG: lse_0978(tagB)
LIV: LIV_1031
LGZ: NCTC10812_01809(tagF_5)
EAN: Eab7_0568
KZO: NCTC404_00414(tagF_2)
LPT: zj316_1958(tagB3)
LPS: LPST_C1593(tagB3)
LPZ: Lp16_1545
LBH: Lbuc_1007
LBN: LBUCD034_1141(tagB)
LSN: LSA_07850
PPEN: T256_05475
PCE: PECL_957
ECAS: ECBG_01909
 » show all
Taxonomy
Reference
1  [PMID:16150696]
  Authors
Bhavsar AP, Truant R, Brown ED
  Title
The TagB protein in Bacillus subtilis 168 is an intracellular peripheral membrane protein that can incorporate glycerol phosphate onto a membrane-bound acceptor in vitro.
  Journal
J Biol Chem 280:36691-700 (2005)
DOI:10.1074/jbc.M507154200
Reference
2  [PMID:17163636]
  Authors
Ginsberg C, Zhang YH, Yuan Y, Walker S
  Title
In vitro reconstitution of two essential steps in wall teichoic acid biosynthesis.
  Journal
ACS Chem Biol 1:25-8 (2006)
DOI:10.1021/cb0500041
Reference
3  [PMID:18215769]
  Authors
Brown S, Zhang YH, Walker S
  Title
A revised pathway proposed for Staphylococcus aureus wall teichoic acid biosynthesis based on in vitro reconstitution of the intracellular steps.
  Journal
Chem Biol 15:12-21 (2008)
DOI:10.1016/j.chembiol.2007.11.011
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.7.8.44
IUBMB Enzyme Nomenclature: 2.7.8.44
ExPASy - ENZYME nomenclature database: 2.7.8.44
BRENDA, the Enzyme Database: 2.7.8.44

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