Transferases;
Transferring sulfur-containing groups;
Sulfurtransferases

thiocarboxylated molybdopterin synthase:cyclic pyranopterin phosphate sulfurtransferase

cyclic pyranopterin phosphate + 2 [molybdopterin-synthase sulfur-carrier protein]-Gly-NH-CH2-C(O)SH + H2O = molybdopterin + 2 molybdopterin-synthase sulfur-carrier protein [RN:R09395]

R09395

cyclic pyranopterin phosphate [CPD:C18239];
[molybdopterin-synthase sulfur-carrier protein]-Gly-NH-CH2-C(O)SH [CPD:C15814];
H2O [CPD:C00001]

Catalyses the synthesis of molybdopterin from cyclic pyranopterin monophosphate. Two sulfur atoms are transferred to cyclic pyranopterin monophosphate in order to form the characteristic ene-dithiol group found in the molybdenum cofactor. Molybdopterin synthase consists of two large subunits forming a central dimer and two small subunits (molybdopterin-synthase sulfur-carrier proteins) that are thiocarboxylated at the C-terminus by EC 2.8.1.11, molybdopterin synthase sulfurtransferase. The reaction occurs in prokaryotes and eukaryotes.

EC 2.8.1.12 created 2011