| Entry |
|
|---|
| Name |
thiosulfate---dithiol sulfurtransferase;
thiosulfate reductase;
TSR
|
|---|
| Class |
Transferases;
Transferring sulfur-containing groups;
Sulfurtransferases
|
|---|
| Sysname |
thiosulfate:dithioerythritol sulfurtransferase
|
|---|
| Reaction(IUBMB) |
thiosulfate + dithioerythritol = sulfite + 4,5-cis-dihydroxy-1,2-dithiacyclohexane (i.e. oxidized dithioerythritol) + sulfide [RN: R05072]
|
|---|
| Reaction(KEGG) |
|
|---|
| Substrate |
|
|---|
| Product |
sulfite [CPD: C00094];
4,5-cis-dihydroxy-1,2-dithiacyclohexane [CPD: C06484];
sulfide [CPD: C00283]
|
|---|
| Comment |
The enzyme from Chlorella shows very little activity towards monothiols such as glutathione and cysteine (cf. EC 2.8.1.3 thiosulfate---thiolsulfurtransferase). The enzyme probably transfers the sulfur atom onto one thiol group to form -S-S-, and sulfide is spontaneously expelled from this by reaction with the other thiol group. May be identical with EC 2.8.1.1 thiosulfate sulfurtransferase.
|
|---|
| History |
EC 2.8.1.5 created 1989, modified 1999
|
|---|
| Pathway |
| ec01120 | Microbial metabolism in diverse environments |
|
|---|
| Reference |
|
|---|
| Authors |
Schmidt A, Erdle I, Gamon B |
|---|
| Title |
Isolation and characterization of thiosulfate reductases from the green alga Chlorella fusca. |
|---|
| Journal |
|
|---|
| Other DBs |
| ExplorEnz - The Enzyme Database: | 2.8.1.5 |
| ExPASy - ENZYME nomenclature database: | 2.8.1.5 |
| BRENDA, the Enzyme Database: | 2.8.1.5 |
|
|---|
