KEGG   ENZYME: 2.8.1.5
Entry
EC 2.8.1.5                  Enzyme                                 
Name
thiosulfate---dithiol sulfurtransferase;
thiosulfate reductase;
TSR
Class
Transferases;
Transferring sulfur-containing groups;
Sulfurtransferases
Sysname
thiosulfate:dithioerythritol sulfurtransferase
Reaction(IUBMB)
thiosulfate + dithioerythritol = sulfite + 4,5-cis-dihydroxy-1,2-dithiacyclohexane (i.e. oxidized dithioerythritol) + sulfide [RN:R05072]
Reaction(KEGG)
R05072
Substrate
thiosulfate [CPD:C00320];
dithioerythritol [CPD:C00950]
Product
sulfite [CPD:C00094];
4,5-cis-dihydroxy-1,2-dithiacyclohexane [CPD:C06484];
sulfide [CPD:C00283]
Comment
The enzyme from Chlorella shows very little activity towards monothiols such as glutathione and cysteine (cf. EC 2.8.1.3 thiosulfate---thiolsulfurtransferase). The enzyme probably transfers the sulfur atom onto one thiol group to form -S-S-, and sulfide is spontaneously expelled from this by reaction with the other thiol group. May be identical with EC 2.8.1.1 thiosulfate sulfurtransferase.
History
EC 2.8.1.5 created 1989, modified 1999
Reference
1  [PMID:24253096]
  Authors
Schmidt A, Erdle I, Gamon B
  Title
Isolation and characterization of thiosulfate reductases from the green alga Chlorella fusca.
  Journal
Planta 162:243-9 (1984)
DOI:10.1007/BF00397446
Other DBs
ExplorEnz - The Enzyme Database: 2.8.1.5
IUBMB Enzyme Nomenclature: 2.8.1.5
ExPASy - ENZYME nomenclature database: 2.8.1.5
BRENDA, the Enzyme Database: 2.8.1.5
CAS: 9059-49-8

  All links  
Protein sequence (12)   
   UniProt (12)   
DNA sequence (16)   
   GenBank (8)   
   EMBL (8)   
All databases (28)   

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