KEGG   ENZYME: 2.8.2.20
Entry
EC 2.8.2.20                 Enzyme                                 
Name
protein-tyrosine sulfotransferase;
tyrosylprotein sulfotransferase;
3'-phosphoadenylyl-sulfate:protein-tyrosine O-sulfotransferase
Class
Transferases;
Transferring sulfur-containing groups;
Sulfotransferases
Sysname
3'-phosphoadenylyl-sulfate:protein-tyrosine O-sulfonotransferase
Reaction(IUBMB)
3'-phosphoadenylyl sulfate + protein tyrosine = adenosine 3',5'-bisphosphate + protein tyrosine-O-sulfate [RN:R02586]
Reaction(KEGG)
R02586
Substrate
3'-phosphoadenylyl sulfate [CPD:C00053];
protein tyrosine [CPD:C00585]
Product
adenosine 3',5'-bisphosphate [CPD:C00054];
protein tyrosine-O-sulfate [CPD:C03721]
Comment
The tyrosine residues of some specific proteins of rat pheochromocytoma cells act as acceptors.
History
EC 2.8.2.20 created 1986
Orthology
K01021  protein-tyrosine sulfotransferase
K22218  protein-tyrosine sulfotransferase
Genes
HSA8459(TPST2) 8460(TPST1)
PTR458726(TPST2) 472398(TPST1)
PPS100981666(TPST2) 100995854(TPST1)
GGO101139944(TPST2) 101146881(TPST1)
PON100454434(TPST1) 100457197(TPST2)
NLE100602727(TPST1) 100606069(TPST2)
MCC696626(TPST1) 715338(TPST2)
MCF101865653(TPST2) 102139730(TPST1)
CSAB103223095(TPST2) 103246579(TPST1)
CATY105575658(TPST2) 105593310(TPST1)
PANU101008780(TPST2) 103882784(TPST1)
TGE112620250(TPST1) 112633326(TPST2)
RRO104671939(TPST2) 104676249(TPST1)
RBB108515847(TPST2) 108543856(TPST1)
TFN117072921(TPST1) 117096118(TPST2)
PTEH111525391(TPST2) 111530459 113219650
CJC100402781(TPST2) 100415662(TPST1)
SBQ101027659(TPST1) 101048210 101053684(TPST2)
CSYR103253854(TPST2) 103255227(TPST1)
MMUR105869391 105870881(TPST2) 105871005(TPST1)
OGA100941875(TPST2) 100952314(TPST1)
MMU22021(Tpst1) 22022(Tpst2)
MCAL110294264(Tpst2) 110294371(Tpst1)
MPAH110312807(Tpst1) 110339075(Tpst2)
RNO288617(Tpst1) 288719(Tpst2)
MCOC116068172(Tpst2) 116068493(Tpst1)
MUN110554333(Tpst2) 110560928(Tpst1)
CGE100757649(Tpst1) 100771893(Tpst2)
PLEU114684313(Tpst2) 114693664 114693665(Tpst1)
NGI103738944(Tpst1) 103746732(Tpst2)
HGL101711599(Tpst1) 101717396(Tpst2)
CPOC100721220(Tpst1) 100721372(Tpst2)
CCAN109688825(Tpst1) 109693032(Tpst2)
DORD105984354(Tpst2) 105998472(Tpst1)
DSP122097925(Tpst2) 122114824(Tpst1)
OCU100338693(TPST2) 100345464(TPST1)
OPI101519485(TPST1) 101534977(TPST2)
TUP102478726(TPST2) 102479475(TPST1)
CFA486332(TPST2) 489788(TPST1)
VVP112923148(TPST2) 112934121(TPST1)
VLG121475617(TPST2) 121488080(TPST1)
AML100474327(TPST1) 100476408(TPST2)
UMR103659261(TPST2) 103670182(TPST1)
UAH113244992(TPST2) 113267749(TPST1)
UAR123784707(TPST1) 123788129(TPST2)
ELK111145570 111160038
LLV125082128 125091079
MPUF101671762(TPST1) 101672200(TPST2)
ORO101364016(TPST1) 101384192(TPST2)
EJU114214378(TPST1) 114225155(TPST2)
ZCA113912731(TPST2) 113933535(TPST1)
MLX117999530(TPST1) 118018611(TPST2)
FCA101091155(TPST2) 101101278(TPST1)
PYU121017782(TPST1) 121022692(TPST2)
PBG122470440(TPST2) 122471381(TPST1)
PTG102958179(TPST2) 102963176(TPST1)
PPAD109250651(TPST1) 109253523(TPST2)
AJU106972860(TPST1) 106978227(TPST2)
HHV120227674(TPST2) 120235692(TPST1)
BTA513004(TPST1) 540183(TPST2)
BOM102276807(TPST1) 102284382(TPST2)
BIU109571371(TPST2) 109578736(TPST1)
BBUB102410119(TPST1) 102411373(TPST2)
CHX102182899(TPST2) 102187284(TPST1)
OAS101104858(TPST2) 101110019(TPST1)
ODA120871217(TPST2) 120877994(TPST1)
CCAD122421726(TPST2) 122433167(TPST1)
SSC100154448(TPST2) 100517581(TPST1)
CFR102503921(TPST2) 102509002(TPST1) 102516104
CBAI105066105(TPST2) 105082752(TPST1)
CDK105089699(TPST1) 105099484(TPST2)
VPC102535278(TPST2) 102536794(TPST1)
BACU103003690(TPST2) 103015335(TPST1)
LVE103074713(TPST2) 103089525(TPST1)
OOR101269603(TPST2) 101272677(TPST1)
DLE111162835(TPST2) 111182081(TPST1)
PCAD102979764(TPST1) 102983870(TPST2)
PSIU116739766(TPST1) 116764893(TPST2)
ECB100059398(TPST2) 100061873(TPST1)
EPZ103550028(TPST2) 103558028(TPST1)
EAI106831852(TPST1) 106841699(TPST2)
MYB102249043(TPST2) 102258440(TPST1) 102259926
MYD102762909(TPST2) 102771855(TPST1)
MMYO118656725(TPST1) 118678194(TPST2)
MLF102426691(TPST1) 102442612(TPST2)
MNA107533860(TPST2) 107543686(TPST1)
PKL118703115(TPST1) 118725747(TPST2)
HAI109377435(TPST1) 109394122(TPST2)
DRO112310325(TPST2) 112314987(TPST1)
SHON118984009(TPST1) 118991241(TPST2)
AJM119042024(TPST1) 119055136(TPST2)
PDIC114506066(TPST1) 114509983(TPST2)
PHAS123806469(TPST1) 123822180(TPST2)
MMF118639791(TPST2) 118642675(TPST1)
RFQ117017723(TPST2) 117025184(TPST1)
PALE102880813(TPST2) 102882492(TPST1)
PGIG120591509(TPST1) 120601932(TPST2)
PVP105296728(TPST1) 105301815(TPST2)
RAY107502452(TPST2) 107507434(TPST1)
MJV108384510(TPST2) 108410360(TPST1)
TOD119241481(TPST1) 119244796(TPST2)
SARA101549217(TPST2) 101554505(TPST1)
LAV100665727(TPST2) 100670456(TPST1)
TMU101345808 101356161
DNM101430955(TPST2) 101432775(TPST1)
MDO100009937(TPST1) 100011282(TPST2)
GAS123232425(TPST2) 123247472(TPST1)
SHR100915171(TPST1) 116420851(TPST2)
PCW110215219(TPST2) 110222144(TPST1)
OAA100075156(TPST2) 100081244(TPST1)
GGA416910(TPST2) 417546(TPST1)
PCOC116228108(TPST1) 116228523(TPST2)
MGP100542914(TPST2) 104909262(TPST1)
CJO107321410(TPST2) 107322498(TPST1)
NMEL110406230(TPST2) 110407851(TPST1)
APLA101791667(TPST1)
ACYG106031072(TPST2) 106041454(TPST1)
AFUL116496100(TPST2) 116497228(TPST1)
TGU100224714(TPST2) 100231926(TPST1)
LSR110478207(TPST2) 110482050(TPST1)
SCAN103818113(TPST2) 103820097(TPST1)
PMOA120507751(TPST1) 120509594(TPST2)
OTC121338828(TPST2) 121345846(TPST1)
PRUF121361803(TPST1) 121364797(TPST2)
GFR102037542(TPST2) 102039260(TPST1)
FAB101808873(TPST1) 101812318(TPST2)
PHI102103318(TPST1) 102109477(TPST2)
PMAJ107211790(TPST2) 107212880(TPST1)
CCAE111936467(TPST2) 111946200(TPST1)
CCW104688646(TPST2) 104691080(TPST1)
ETL114060443(TPST1) 114066058(TPST2)
ZAB102061047(TPST2) 102074689(TPST1)
FPG101912194(TPST2) 101919555(TPST1)
FCH102054159(TPST1) 102058320(TPST2)
CLV102086711(TPST1) 102091967(TPST2)
EGZ104122582(TPST2) 104131922(TPST1)
NNI104015775(TPST2) 104016058(TPST1)
ACUN113486295(TPST2) 113487202(TPST1)
TALA104368898(TPST1) 104369285(TPST2)
PADL103924831(TPST1) 103925645(TPST2)
ACHC115345763(TPST2) 115347140(TPST1)
AAM106492551(TPST2) 106495363(TPST1)
AROW112960736(TPST1) 112963354(TPST2)
NPD112945191(TPST2) 112945404(TPST1)
DNE112986383(TPST1) 112989033(TPST2)
ASN102381170(TPST1) 102385474(TPST2)
AMJ102560068(TPST2) 102566332(TPST1)
CPOO109312593(TPST2) 109317064(TPST1)
GGN109290628(TPST2) 109293435(TPST1)
PSS102453626(TPST1) 102460081(TPST2)
CMY102932566(TPST1) 102946687(TPST2)
CPIC101949330(TPST2) 101952533(TPST1)
TST117867349(TPST1) 117888045(TPST2)
CABI116818713(TPST2) 116821336(TPST1)
MRV120386136(TPST2) 120387289(TPST1)
PVT110083448(TPST2) 110084505(TPST1)
SUND121916813(TPST1)
PBI103047966(TPST2) 103063767(TPST1)
PMUR107287086(TPST1) 107287309(TPST2)
TSR106543820(TPST1) 106550348(TPST2)
PGUT117667531(TPST1) 117672308(TPST2)
VKO123028627(TPST2) 123036716(TPST1)
PMUA114585137(TPST1) 114586495(TPST2)
ZVI118076369(TPST2) 118097135(TPST1)
GJA107112497(TPST1) 107118892(TPST2)
XLA108707091(tpst2.S) 108709642 444016(tpst1.L) 495291(tpst2.L)
XTR549785(tpst2) 595028(tpst1)
NPR108787293(TPST1) 108793978(TPST2)
RTEM120926644(TPST1) 120937706(TPST2)
BBUF120988823(TPST2) 120995525(TPST1)
BGAR122924369(TPST2) 122931613(TPST1)
DRE30677(tpst1) 393171(tpst1l)
SRX107710537 107729121(tpst1) 107741684 107758592
SANH107657564 107658629 107662793 107667440 107673841 107689990
SGH107570812 107586256(tpst1) 107589027 107590047
CCAR109045232 109090399 109090403 109103347 109103739
CAUA113038429 113054632 113058407 113064013 113110325 113115134
IPU100304582(tpst2) 108277496(tpst1) 108279036(tpst1l)
PHYP113532796 113541455 113544707
SMEO124393680(tpst2) 124394706(tpst1) 124398176(tpst1l)
AMEX103025893 103028768 103042095(tpst1)
EEE113569685 113573838(tpst1) 113584016
TRU101064708(tpst1) 101073940
TNGGSTEN00026860G001 GSTEN00029956G001
LCO104928580
NCC104950625(tpst1) 104964488
CGOB115017946 115018494(tpst1)
ELY117260011(tpst1) 117261240
PLEP121943000(tpst1) 121952220(tpst1l)
SLUC116036958 116040333(tpst1)
ECRA117942113(tpst1) 117955385
PFLV114553299 114567409(tpst1)
GAT120821795(tpst1l) 120823037(tpst1)
PPUG119215601 119215620(tpst1)
MSAM119882600(tpst1) 119895220
CUD121518474(tpst1l) 121525375(tpst1)
MZE101477589 101482118(tpst1)
ONL100690740 100691291
OAU116311457(tpst1) 116319680
OLA101156109 101161430
OML112136383(tpst1) 112139054 112142950(tpst1l)
XMA102219783(tpst1) 102228781
XCO114152942(tpst1) 114162086
XHE116708112 116728987(tpst1)
PRET103474349(tpst1) 103475655
PFOR103139105(tpst1) 103147309
PLAI106938797 106939909
PMEI106907012(tpst1) 106909433
GAF122832180(tpst1) 122844556(tpst1l)
CVG107084156(tpst1) 107091218
CTUL119792694(tpst1l) 119796176(tpst1)
GMU124876166 124884271(tpst1)
NFU107380745(tpst1) 107386765
KMR108238895 108248066(tpst1)
ALIM106524045 106525429(tpst1) 106534974
NWH119410473(tpst1) 119420508
AOCE111580882(tpst1) 111581225
CSEM103377640 103395453(tpst1)
POV109630399(tpst1)
SSEN122773388(tpst1) 122780111(tpst1l)
HHIP117772547(tpst1) 117774440(tpst1l)
LCF108893491 108900367
SDU111217243(tpst1) 111226285
SLAL111647454(tpst1) 111665478
XGL120791714(tpst1) 120802948(tpst1l)
HCQ109532038(tpst1)
BPEC110155918(tpst1) 110168239
MALB109957371(tpst1) 109960022
SASA106568446 106581522 106602840(tpst1) 106613355
OTW112216710(tpst1l) 112220228(tpst2) 112238923 112238986
OMY110490092(tpst1l) 110503266 110508082 110523402(tpst2)
OGO123992489 123994787(tpst1l) 124005041 124049125(tpst2)
ONE115106804(tpst1) 115121479 115123698 115125128
SALP111950558(tpst1) 111960886 112074598 112076175
SNH120025882(tpst2) 120028346 120039095(tpst1) 120057423(tpst1l)
ELS105008596(tpst1) 105015225 105015511
SFM108930048 108932415(tpst1) 114910718
PKI111851485 111861090(tpst1)
AANG118209495(tpst1) 118212949(tpst2) 118234826
LOC102685418(tpst1) 102689636(tpst2)
PSPA121300390 121307766 121308652
ARUT117426848 117428357 117429079 117430164
LCM102364059(TPST2) 102364758(TPST1)
CMK103180643 103189950
RTP109914976(tpst2) 109937108(tpst1)
BFO118426073
BBEL109468844
CIN100181744
SCLV120325689 120325690 120329477 120329630 120330323 120331980 120335891 120335893 120335894 120335896 120335898
SPU115926705 579762
APLC110977000 110984859
SKO100373767 100373916
DMEDmel_CG32632(Tpst)
DER6551022
DSE6618427
DSIDsimw501_GD17135(Dsim_GD17135)
DYADyak_GE17090
DAN6505233
DSR110184163
DPODpse_GA26942
DPE6598186
DMN108159421
DWI6644536
DGR6565434
DMODmoj_GI14854
DAZ108619521
DNV108657163
DHE111597420
DVI6631783
CCAT101454887
BOD106616091
MDE101893374
SCAC106087975
LCQ111678110
AGAAgaP_AGAP000900
ACOZ120957544
AARA120905826
AAG5572543
AALB109409456 109415320
CQUCpipJ_CPIJ014255 CpipJ_CPIJ017505
CPII120430982
CNS116340282
AME552278
ACER107998179
ALAB122712227
BIM100745484
BBIF117205932
BVK117235448
BVAN117153948
BTER100648160
BPYO122577919
CCAL108626261
OBB114871342
MGEN117227681
NMEA116432163
CGIG122398279
SOC105207782
MPHA105838794
AEC105145889
ACEP105625213 105625214
PBAR105432715
VEM105562805
HST105189261
DQU106752046
CFO105248709
FEX115242870
LHU105673267
PGC109857848
OBO105280402
PCF106785477
PFUC122513987
VPS122633689
NVI100123184
CSOL105368981
TPRE106657406
MDL103568660
CGLO123265550
FAS105263065
DAM107044553
AGIF122857310
CCIN107267746
TCA656373
DPA109545455
SOY115886759
ATD109601122 109606355
CSET123314451
AGB108904589
LDC111502938
APLN108736474
PPYR116181702
OTU111426862
BMOR101739802
BMAN114242103
MSEX115448064
DPLKGM_204752
BANY112052597
PMAC106713855
PXU106128533
PRAP110995677
ZCE119834962
HAW110379498
TNL113504681
OFU114355904 114355906
PXY105394176
API100160328
DNX107167197
AGS114123843
RMD113557797
BTAB109040730
CLEC106664801
HHAL106677518
NLU111053632
PHUPhum_PHUM217150
FOC113202476
ZNE110828048 110839462
CSEC111862894
FCD110851292
DPXDAPPUDRAFT_209116
DMK116919483
PVM113819337
PJA122248906
HAME121869573
PCLA123747512 123764736 123769834
PTRU123501745
HAZT108678397
EAF111701321 111703772 111709398 111715501
ISCIscW_ISCW009297
DSV119445832
RSAN119390246
RMP119173004
VDE111245971 111252777
VJA111259832 111265361
TUT107367096
DPTE113789240
DFR124492158
CSCU111617876
PTEP107437210
SDM118180466 118205701
CELCELE_F42G9.8(tpst-2) CELE_Y111B2A.15(tpst-1)
CBRCBG_03560(Cbr-tpst-1) CBG_15241(Cbr-tpst-2)
BMYBM_BM7290(Bm7290)
LOALOAG_03971
NAINECAME_00889 NECAME_11981
TSPTsp_01013
HROHELRODRAFT_77670
LGILOTGIDRAFT_119963 LOTGIDRAFT_139716 LOTGIDRAFT_190158
PCAN112562177
BGT106054309
GAE121368337
HRF124118489
HRJ124280833
CRG105335603 105339772
MYI110442488 110460930
PMAX117332885 117337526
MMER123534251 123534400
OBI106875251
OSN115212942
LAK106153755 106154534
SMMSmp_129700 Smp_145910 Smp_145920 Smp_147690
SHXMS3_0015744 MS3_0016944
OVIT265_12023 T265_12582 T265_12970 T265_13923 T265_14688 T265_15531 T265_15751
EGLEGR_02151
NVE5510513
EPA110254891
ATEN116307155
AMIL114964813
PDAM113683479
SPIS111327861
DGT114530970
AQU100631816
ATHAT1G08030(TPST)
ALY9328491
CRB17898466
CSAT104739385 104754980 104766142
EUSEUTSA_v10007441mg
BRP103836408 103871547
BNA106346365 106346366 106359394 106362274 106411735 106433216
BOE106309887 106343721
RSZ108819645 108821320 108834427 108862166
THJ104800598 104826371
CPAP110826114
CIT102622908
CICCICLE_v10028288mg
PVY116142391 116143625
MINC123208305 123226404
TCC18590889
GRA105788953
GHI107962061 107963886
GAB108483818
DZI111285672
EGR104432883
GMX100810026
GSJ114377605
PVUPHAVU_011G080300g
VRA106754522
VAR108338836
VUN114170721
CCAJ109799316
APRC113858624
MTRMTR_4g058890
CAM101493115
LJALj0g3v0141259.1(Lj0g3v0141259.1) Lj0g3v0141259.3(Lj0g3v0141259.3)
ADU107462067 107463583
AIP107613661 107613791
AHF112707002 112708143 112771896 112772014
LANG109325532 109355316
FVE101295888
RCN112167239
PPER18772752
PMUM103343350
PAVI110772506
PDUL117631514
MDM103422861 103423021
PXB103956756
ZJU107411365
MNT21391434
CSV101207379 116404616 116406420
CMO103500982
BHJ120082650
MCHA111020531
CMAX111468614 111469311
CMOS111444254 111464808
CPEP111783422 111798198
RCU8266268
JCU105628080
HBR110645003
MESC110613871
POP7463302
PEU105139597
PALZ118034744
JRE108990118 109008600
QSU112016923
QLO115983371
TWL120001253 120012346
VVI100255229
VRI117916151
SLY101261094
SPEN107005098
SOT102585997
CANN107848027
NTA107788779 107831476
NSY104242491
NTO104113366
NAU109220863
INI109162305 109173450
ITR116004072 116024155 116024432 116025977
SIND105170288 105170727
OEU111369911 111372802 111385609 111393501
EGT105949181
SSPL121741157 121743610
HAN110868383 110875454
ECAD122581276 122604013
LSV111886059 111899889
CCAV112519442 112523853
DCR108219831 108224250
CSIN114274529
BVG104903227
SOE110776614
CQI110711830 110737283
NNU104594871
MING122057849
TSS122652822 122656749
PSOM113298608 113307674 113310125 113320273
NCOL116265277 116265677 116267497 116267498 116267692
OSA9267276
DOSAOs06t0158200-01(Os06g0158200)
OBR102703043
BDI100828854
ATS109765635
TDC119329705 119336851
TAES123149713 123156765 123165493
SBI8071351 8071352
ZMA100192103 100280275
SITA101764318
SVS117852056
PVIR120670151 120702681
PHAI112889625
PDA103718253
EGU105055663
MUS103981066 103992423
DCT110102995
PEQ110024958
AOF109823173
ATR18995795
SMOSELMODRAFT_412798 SELMODRAFT_445790
PPP112293313
CRECHLRE_01g022600v5
VCNVOLCADRAFT_121526
MNGMNEG_11528
CSLCOCSUDRAFT_83578
CVRCHLNCDRAFT_56881
APROF751_2022
OLUOSTLU_17201
OTAOT_ostta11g00010
BPGBathy18g01560
MPPMICPUCDRAFT_41621
AMALI607_16685
AMAEI876_17000
AMAOI634_16930
MBUREQU24_11955
MPSYCEK71_01135
MMOBF6R98_19665
NWRE3U44_08290
TEETel_13505 Tel_13520
KKOKkor_0922
KSDKS2013_1453
ACOMCEW83_08230
PCAYFRD00_13430
GSPIGS75_08085
ALIAZOLI_p60202
AZMDM194_27250
AOZHUE56_00050
PBRPB2503_06802
PPMPPSC2_05995(tysT)
PPOPPM_1133(tysT)
PPOYRE92_05890
MARMAE_15710
MPKVL20_4656
CWACwatDRAFT_3967
FMRFuma_03297
SDYNMal52_02190
TTZFHG85_12920
FUVJR347_16565
 » show all
Reference
1  [PMID:6577005]
  Authors
Lee RW, Huttner WB.
  Title
Tyrosine-O-sulfated proteins of PC12 pheochromocytoma cells and their sulfation by a tyrosylprotein sulfotransferase.
  Journal
J Biol Chem 258:11326-34 (1983)
Other DBs
ExplorEnz - The Enzyme Database: 2.8.2.20
IUBMB Enzyme Nomenclature: 2.8.2.20
ExPASy - ENZYME nomenclature database: 2.8.2.20
BRENDA, the Enzyme Database: 2.8.2.20
CAS: 87588-33-8

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