KEGG   ENZYME: 2.8.2.21
Entry
EC 2.8.2.21                 Enzyme                                 
Name
keratan sulfotransferase;
3'-phosphoadenylyl keratan sulfotransferase;
keratan sulfate sulfotransferase;
3'-phosphoadenylylsulfate:keratan sulfotransferase;
3'-phosphoadenylyl-sulfate:keratan 6'-sulfotransferase
Class
Transferases;
Transferring sulfur-containing groups;
Sulfotransferases
Sysname
3'-phosphoadenylyl-sulfate:keratan 6'-sulfonotransferase
Reaction(IUBMB)
3'-phosphoadenylyl sulfate + keratan = adenosine 3',5'-bisphosphate + keratan 6'-sulfate [RN:R03553]
Reaction(KEGG)
R03553
Substrate
3'-phosphoadenylyl sulfate [CPD:C00053];
keratan [CPD:C00573]
Product
adenosine 3',5'-bisphosphate [CPD:C00054];
keratan 6'-sulfate [CPD:C00573]
Comment
Sulfation takes place at the 6-position of galactosyl and N-acetylglucosaminyl residues in keratan, a proteoglycan. Not identical with EC 2.8.2.5 (chondroitin 4-sulfotransferase), EC 2.8.2.6 (choline sulfotransferase) or EC 2.8.2.17 (chondroitin 6-sulfotransferase).
History
EC 2.8.2.21 created 1989
Pathway
ec00533  Glycosaminoglycan biosynthesis - keratan sulfate
Orthology
K01022  keratan sulfate 6-sulfotransferase 1
Genes
HSA8534(CHST1)
PTR466500(CHST1)
PPS100979080(CHST1)
GGO101136055(CHST1)
PON100936783(CHST1)
NLE100607513(CHST1)
MCC715176(CHST1)
MCF102121159(CHST1)
CSAB103236789(CHST1)
CATY105592782(CHST1)
PANU101013876(CHST1)
TGE112606397(CHST1)
RRO104668375(CHST1)
RBB108519267(CHST1)
TFN117080202(CHST1)
PTEH111544925(CHST1)
CJC100403467(CHST1)
SBQ101041677(CHST1)
MMUR105875940 105885344(CHST1)
OGA100952546(CHST1)
MMU76969(Chst1)
MCAL110290078(Chst1)
MPAH110318543(Chst1)
RNO295934(Chst1)
MCOC116090507(Chst1)
MUN110549877(Chst1)
CGE100774066(Chst1)
PLEU114699717(Chst1)
NGI103751543(Chst1)
HGL101709273(Chst1)
CPOC100722965(Chst1)
CCAN109692002(Chst1) 109696439
DORD105996045(Chst1)
DSP122105019(Chst1)
OCU100348291(CHST1)
OPI101534226(CHST1)
TUP102494285(CHST1)
CFA483642(CHST1)
VVP112924106(CHST1)
VLG121471790(CHST1)
AML100472620(CHST1)
UMR103672398(CHST1)
UAH113265001(CHST1)
UAR123799588(CHST1)
ELK111149624
LLV125079027
MPUF101693600(CHST1)
ORO101363802(CHST1)
EJU114215397(CHST1)
ZCA113913961(CHST1)
MLX118015796(CHST1)
FCA101085495(CHST1)
PYU121043492(CHST1)
PBG122483741(CHST1)
PTG102972740(CHST1)
PPAD109279239(CHST1)
AJU106978039(CHST1)
HHV120228395(CHST1)
BTA506932(CHST1)
BOM102269216(CHST1)
BIU109569674(CHST1)
BBUB102400240(CHST1)
CHX102182814(CHST1)
OAS101112159(CHST1)
ODA120876920(CHST1)
CCAD122449734(CHST1)
SSC100519885(CHST1)
CFR102507446(CHST1)
CBAI105076480(CHST1)
CDK105106847(CHST1)
VPC102540752(CHST1)
BACU103002842(CHST1)
LVE103089266(CHST1)
OOR101282618(CHST1)
DLE111183998(CHST1)
PCAD102993471(CHST1)
PSIU116757375(CHST1)
EPZ103554341(CHST1)
EAI106843980(CHST1)
MYB102242164(CHST1)
MYD102766961(CHST1)
MMYO118665100(CHST1)
MLF102417931(CHST1)
MNA107530332(CHST1)
PKL118713128(CHST1)
HAI109390240(CHST1)
DRO112303461(CHST1)
SHON119002969(CHST1)
AJM119064452(CHST1)
PDIC114500478(CHST1)
PHAS123810189(CHST1)
MMF118628779(CHST1)
RFQ117030314(CHST1)
PALE102892829(CHST1)
PGIG120606502(CHST1)
PVP105290003(CHST1)
RAY107511876(CHST1)
MJV108384923(CHST1)
TOD119255329(CHST1)
SARA101541294(CHST1)
LAV100654881(CHST1)
TMU101342127
DNM101446465(CHST1)
MDO100011264(CHST1)
GAS123251456(CHST1)
SHR116419728(CHST1)
PCW110224045(CHST1)
OAA100074919(CHST1)
GGA428866(CHST1)
PCOC116229183(CHST1)
MGP100550392(CHST1)
CJO107314790(CHST1)
NMEL110401825(CHST1)
APLA101796672(CHST1)
ACYG106043347(CHST1)
AFUL116489883(CHST1)
TGU100218131(CHST1)
LSR110472086(CHST1)
SCAN103826672(CHST1)
PMOA120500433(CHST1)
OTC121331748(CHST1)
PRUF121349497(CHST1)
GFR102031769(CHST1)
FAB101821527(CHST1)
PHI102102314(CHST1)
PMAJ107206472(CHST1)
CCAE111930194(CHST1)
CCW104698272(CHST1)
ETL114059265(CHST1)
ZAB102063054(CHST1)
FPG101914171(CHST1)
FCH102059692(CHST1)
CLV102090832(CHST1)
EGZ104134086(CHST1)
NNI104020366(CHST1)
ACUN113480763(CHST1)
TALA104360893(CHST1)
PADL103912826(CHST1)
ACHC115338349(CHST1)
AAM106498277(CHST1)
AROW112966097(CHST1)
NPD112942523(CHST1)
DNE112987590(CHST1)
ASN102377269(CHST1)
AMJ102576487(CHST1)
CPOO109321104(CHST1)
GGN109298923(CHST1)
PSS102450260(CHST1)
CMY102947896(CHST1)
CPIC101951161(CHST1)
TST117876952(CHST1)
CABI116821724(CHST1)
MRV120405420(CHST1)
ACS100556876(chst1)
PVT110082498(CHST1)
SUND121920023(CHST1)
PBI103058223(CHST1)
PMUR107295531(CHST1)
TSR106544186(CHST1)
PGUT117665501(CHST1)
VKO123026937(CHST1)
PMUA114596166(CHST1)
ZVI118087533(CHST1)
GJA107113395(CHST1)
XLA108710801 108713774(chst1.L) 108715239(chst1.S)
XTR100485856 100492654(chst1)
NPR108785449(CHST1) 108788171
RTEM120917115(CHST1) 120932665
BBUF120980512(CHST1) 121003942
BGAR122921052(CHST1) 122926092
DRE100002270(si:ch73-62b13.1) 445124(chst1)
SRX107707501 107714082 107740436 107749314
SANH107654120 107654173 107664683 107672215 107674940
SGH107553958 107572125 107583921 107589170
CCAR109050588 109066084 109067715 109069229 109069501 109109507 109111289
CAUA113061263 113066808 113096594 113096598 113118777
IPU108264188 108264694(si:ch73-62b13.1) 108269117(chst1) 124626686 124626797 124627181
PHYP113526458 113534694 113546558
SMEO124385628(chst1) 124395435
AMEX103023582 103042358 103042895
EEE113570891 113581797 113592085
TRU101070681(chst1) 101077034
TNGGSTEN00013178G001 GSTEN00015905G001 GSTEN00018215G001
LCO104925835(chst1) 104935271 104939683
NCC104951776 104967808(chst1)
CGOB115010312 115028701(chst1)
ELY117253452(si:ch73-62b13.1) 117260555(chst1) 117261828
PLEP121945261 121950583(si:ch73-62b13.1) 121950588
SLUC116038680(si:ch73-62b13.1) 116040950(chst1)
ECRA117946945(chst1) 117948640(si:ch73-62b13.1)
PFLV114558994(chst1) 114560566
GAT120808808(chst1) 120809706 120812789
PPUG119196586(si:ch73-62b13.1) 119198696(chst1)
MSAM119890801 119893050(chst1) 119894315(si:ch73-62b13.1)
CUD121512019 121515419(chst1) 121515624(si:ch73-62b13.1)
MZE101467859 101471982(chst1) 101472749
ONL100698759 100705607 100711854(chst1)
OAU116312574(si:ch73-62b13.1) 116329480(chst1) 116331012
OLA101159731(chst1) 101165141 105354170
OML112141243 112152082(si:ch73-62b13.1) 112161296(chst1)
XMA102227014 102236602(chst1)
XCO114137610 114143731(chst1)
XHE116718969(chst1) 116734440 116734445
PRET103462734(chst1) 103466195
PFOR103144398 103153589(chst1)
PLAI106953112(chst1) 106962157
PMEI106926180 106927368(chst1)
GAF122819890(chst1) 122835856(si:ch73-62b13.1)
CVG107082445 107094056(chst1)
CTUL119796331(chst1) 119796847(si:ch73-62b13.1)
GMU124861327(si:ch73-62b13.1) 124867157(chst1)
NFU107381806(chst1) 107389055
KMR108234746(chst1) 108237443(si:ch73-62b13.1)
ALIM106519099(chst1) 106523208
NWH119415597(si:ch73-62b13.1) 119430248(chst1)
AOCE111563369 111574910(chst1) 111583800
CSEM103378793(chst1) 103379596 103398782
POV109624249 109637187(chst1) 109638942
SSEN122771976(chst1) 122775490 122775528(si:ch73-62b13.1)
HHIP117759261(chst1) 117763374 117763584(si:ch73-62b13.1)
LCF108875404 108879800 108887792 108902229
SDU111219181 111224401(chst1) 111228655
SLAL111647705 111654318(chst1) 111661784
XGL120792747(si:ch73-62b13.1) 120793411 120794366
HCQ109525715(chst1) 109530398
BPEC110165884 110174495 110174496(chst1)
MALB109961860 109965056(chst1)
SASA100380468(chst1) 106561444 106561610 106573154 106573294 106593337
OTW112219135 112219152 112232081 112241710 112253390
OMY110497842 110499877 110513834 110522853 110524544 118964962
OGO123992876 123993140 123997493 124001488 124021784
ONE115108966 115108993 115132716 115134711
SALP111952822 111952950 111961183 111962752
SNH120039875 120039876 120053501 120053532 120065924 120066187
ELS105013579 105018170 105018272
SFM108935930 108940844(chst1) 108942484
PKI111838707 111841584(chst1)
AANG118214751 118226882
LOC102688946(chst1) 102698485
PSPA121294449 121317797 121319087 121330202
ARUT117414677(si:ch73-62b13.1) 117419372 117432365 117434655
LCM102346083 102366374(CHST1)
CMK103175104(chst1) 103179901(si:ch73-62b13.1)
RTP109914878 109928543(chst1)
BFO118403711 118406106 118411215 118425790
BBEL109461915 109461918 109461919 109463393 109467185 109468950 109472099 109474311 109475096 109476797 109482821 109486052 109486213
CIN100179226 100185440 100185779 100186569 113475152
SCLV120336142 120336596 120338205 120342796 120342834 120343329 120346943 120347902
SPU100889433 100891836 100891876 105440812 115919258 115929052 579709 579726 581661 586919
APLC110988559 110988984
SKO100369364 100369810 100370159 100370459 100370508 100371056 100371406 100372859 100374899 100378047 100378605 102801856 102801868 102802384 102803307 102804296 102804943 102805897 102805926 102805927 102806029 102806041 102806646 102806828 102807901 102808479 102809528 102809916
AGAAgaP_AGAP009809
ACOZ120956914
CPII120418945
PVM113821846
PJA122244645 122250163 122253044 122259534 122263103 122263327 122266089
HAME121863003 121864037 121866849 121873681
PCLA123754373
PTRU123513441
HAZT108675220 108681624
EAF111715026
ISCIscW_ISCW015777 IscW_ISCW016341
VJA111272755
TUT107369571
DPTE113790282 113792871
DFR124491605
PTEP107439934
LGILOTGIDRAFT_156733 LOTGIDRAFT_166330 LOTGIDRAFT_231254
PCAN112558282
BGT106072004
GAE121380425 121385069 121385420
HRF124116118 124126497 124130656 124136826 124136827 124139054 124149090 124151161
HRJ124256631 124267454 124273329 124280169
CRG105319013 105327266 105335542 105335808 105337601 105338154 105339107 105342433 105346868 117681315 117692728
MYI110446936 110449140 110450533 110456049 110459038 110459039 110461726
PMAX117318121 117322669 117330170 117330498 117330893 117331067 117331149 117332315 117335754 117340542 117341352 117341653 117341654 117341812
MMER123523228 123526586 123529919 123530135 123530401 123530801 123534229 123534601 123537928 123543334 123543351 123543863 123544995 123549021 123552223 123552878 123555249 123559816 123560886 123562801 123563562 123565635 123565761 123566039 123566217 123566380
OSN115221016
LAK106153296 106153297 106173748 106179833 106180902 106181961 112041415
NVE5506879 5513039 5516795 5518785
EPA110239985 110242708 110248851 110252770 110254152
ATEN116295018 116302925 116303806 116303822 116306891
ADF107331137 107334053 107347784
AMIL114960125 114976959
PDAM113665157 113673800 113674423 113675211 113676207 113677237 113682223 113682955
SPIS111322134 111323062 111323131 111327312 111330124 111331612 111336724 111336731
DGT114518378
XEN124452598
HMG100213095 105845892
GAIIMCC3135_07610
 » show all
Reference
1  [PMID:6592165]
  Authors
Ruter ER, Kresse H.
  Title
Partial purification and characterization of 3'-phosphoadenylylsulfate:keratan sulfate sulfotransferases.
  Journal
J Biol Chem 259:11771-6 (1984)
Other DBs
ExplorEnz - The Enzyme Database: 2.8.2.21
IUBMB Enzyme Nomenclature: 2.8.2.21
ExPASy - ENZYME nomenclature database: 2.8.2.21
BRENDA, the Enzyme Database: 2.8.2.21
CAS: 62168-79-0

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