KEGG   ENZYME: 2.8.2.24Help
Entry
EC 2.8.2.24                 Enzyme                                 

Name
aromatic desulfoglucosinolate sulfotransferase;
desulfoglucosinolate sulfotransferase (ambiguous);
PAPS-desulfoglucosinolate sulfotransferase (ambiguous);
3'-phosphoadenosine-5'-phosphosulfate:desulfoglucosinolate sulfotransferase (ambiguous)
Class
Transferases;
Transferring sulfur-containing groups;
Sulfotransferases
BRITE hierarchy
Sysname
3'-phosphoadenylyl-sulfate:aromatic desulfoglucosinolate sulfotransferase
Reaction(IUBMB)
(1) 3'-phosphoadenylyl sulfate + desulfoglucotropeolin = adenosine 3',5'-bisphosphate + glucotropeolin [RN:R03214];
(2) 3'-phosphoadenylyl sulfate + indolylmethyl-desulfoglucosinolate = adenosine 3',5'-bisphosphate + glucobrassicin [RN:R08167]
Reaction(KEGG)
Substrate
3'-phosphoadenylyl sulfate [CPD:C00053];
desulfoglucotropeolin [CPD:C01069];
indolylmethyl-desulfoglucosinolate [CPD:C16517]
Product
adenosine 3',5'-bisphosphate [CPD:C00054];
glucotropeolin [CPD:C02153];
glucobrassicin [CPD:C05837]
Comment
This enzyme, characterized from cruciferous plants, catalyses the last step in the biosynthesis of tryptophan- and phenylalanine-derived glucosinolates. cf. EC 2.8.2.38, aliphatic desulfoglucosinolate sulfotransferase.
History
EC 2.8.2.24 created 1992, modified 2017
Pathway
ec00380  Tryptophan metabolism
ec00966  Glucosinolate biosynthesis
ec01110  Biosynthesis of secondary metabolites
Orthology
K11821  aromatic desulfoglucosinolate sulfotransferase
Genes
RSS: 109442413
ATH: AT1G74100(SOT16)
ALY: ARALYDRAFT_895283
CRB: 17894300
CSAT: 104704865 104713044
EUS: EUTSA_v10018795mg
BRP: 103831884(ST5a-2) 103852881(ST5a)
BNA: 106354325 106354366 106381227 106381367 106415773 111199316
BOE: 106296616 106327830
Taxonomy
Reference
1  [PMID:2524977]
  Authors
Jain JC, Reed DW, GrootWassink JW, Underhill EW.
  Title
A radioassay of enzymes catalyzing the glucosylation and sulfation steps of glucosinolate biosynthesis in Brassica species.
  Journal
Anal Biochem 178:137-40 (1989)
DOI:10.1016/0003-2697(89)90369-2
Reference
2  [PMID:16367753]
  Authors
Klein M, Reichelt M, Gershenzon J, Papenbrock J.
  Title
The three desulfoglucosinolate sulfotransferase proteins in Arabidopsis have different substrate specificities and are differentially expressed.
  Journal
FEBS J 273:122-36 (2006)
DOI:10.1111/j.1742-4658.2005.05048.x
  Sequence
[ath:AT1G74100]
Reference
3  [PMID:19077143]
  Authors
Klein M, Papenbrock J
  Title
Kinetics and substrate specificities of desulfo-glucosinolate sulfotransferases in Arabidopsis thaliana.
  Journal
Physiol Plant 135:140-9 (2009)
DOI:10.1111/j.1399-3054.2008.01182.x
  Sequence
[ath:AT1G74100]
Other DBs
ExplorEnz - The Enzyme Database: 2.8.2.24
IUBMB Enzyme Nomenclature: 2.8.2.24
ExPASy - ENZYME nomenclature database: 2.8.2.24
BRENDA, the Enzyme Database: 2.8.2.24
CAS: 121479-85-4

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