KEGG   ENZYME: 2.8.2.37
Entry
EC 2.8.2.37                 Enzyme                                 
Name
trehalose 2-sulfotransferase;
Stf0 sulfotransferase;
3'-phosphoadenylyl-sulfate:alpha,alpha-trehalose 2-sulfotransferase
Class
Transferases;
Transferring sulfur-containing groups;
Sulfotransferases
Sysname
3'-phosphoadenylyl-sulfate:alpha,alpha-trehalose 2-sulfonotransferase
Reaction(IUBMB)
3'-phosphoadenylyl sulfate + alpha,alpha-trehalose = adenosine 3',5'-bisphosphate + 2-O-sulfo-alpha,alpha-trehalose [RN:R10971]
Reaction(KEGG)
R10971
Substrate
3'-phosphoadenylyl sulfate [CPD:C00053];
alpha,alpha-trehalose [CPD:C01083]
Product
adenosine 3',5'-bisphosphate [CPD:C00054];
2-O-sulfo-alpha,alpha-trehalose [CPD:C20985]
Comment
The sulfation of trehalose in the bacterium Mycobacterium tuberculosis is required for the biosynthesis of sulfolipid-1.
History
EC 2.8.2.37 created 2014
Orthology
K21014  trehalose 2-sulfotransferase
Genes
LEZGLE_2492
LEMLEN_2518
PSAPST_1401
SBLSbal_1699
SBSSbal117_1812
SBBSbal175_2640
PAGAPAGA_a2042
PCARPC2016_1536
AMGAMEC673_07475
ALRDS731_04820
ALEAV939_17530
ALZAV940_17230
APELCA267_005060
SALMD0Y50_03620
SALKFBQ74_13645
MPSYCEK71_13120 CEK71_14265
HCAMI4484_09085
HSXHNO51_08795
HSVHNO53_12130
REVHUE57_01120 HUE57_01125
BCEDDM42_947
BTEIWS51_14685
BFNOI25_820
JALBZG29_04290
IDCLRM40_02130
NITNAL212_0593
NURATY38_02950
MBACBN1209_1170
GEBGM18_0971
GSUBKP001_21515
MLOmll3788
MLNA9174_06825
MCIMesci_1366 Mesci_1869
MOPMesop_1388 Mesop_6620
MAMMesau_01404
MAMOA6B35_00680
MESWA9K65_007020 A9K65_009765
MESPC1M53_24955
MHUAMCHK_5143
MJREB229_07015
MERDEB233_06935 EB233_24795 EB233_31880
PHTBLM14_22300
RBSRHODOSMS8_00998(stf0)
SMESMc01744
SMKSinme_2280
SMQSinmeB_2124
SMXSM11_chr0957
SMIBN406_02129
SMEGC770_GR4Chr2358
SMELSM2011_c01744
SMERDU99_12855
AVIAvi_3258
KAIK32_31720
MNOMnod_7038
DEQXM25_13065
YTIFNA67_16790
MMEDMame_00018
NOHG5V57_22275
LAPACP90_01825 ACP90_23520
LABRCHH27_20440
LABPFJ695_23935
LABTFIU93_01275 FIU93_07450
LAGGB0E33_06980 B0E33_13340
SIWGH266_21045
SILSPO3420
JANJann_2787
REDroselon_00619
YPACCEW88_23565
SUAMBOO69_08760
SULZC1J03_19535
SMEDJNX03_04910
TOMBWR18_16245 BWR18_21205
RIDRIdsm_04035 RIdsm_04606
THAACFI11_06985
PAMIJCM7686_1672 JCM7686_pAMI4p230
PCONB0A89_05610
PARUCYR75_12500 CYR75_12505
PARSDRW48_09740
PMAUCP157_03559
RSUNHU_03816
DAAAKL17_2081
RBGBG454_18145
BOOE2K80_01535
LITFPZ52_07065 FPZ52_16980 FPZ52_18290
PPRUFDP22_03420 FDP22_10620 FDP22_23270
PAMOBAR1_07600
POZI0K15_05295
FAPGR316_08645
MMRMmar10_2509
SPAPH3Z74_01835
SHUMSTHU_13100 STHU_17430 STHU_20770
STELSTAQ_10650 STAQ_18640 STAQ_36380 STAQ_36490
RRURru_A1625
RRFF11_08385
DEXHWD60_10125
PDUPDUR_14345
PALBEJC50_00250
PBKBack11_46270 Back11_56650
PRZGZH47_02235
PLYCGXP70_16895
PCELHUB94_16800
COHNKCTCHS21_28750
MTURv0295c
MTVRVBD_0295c
MTCMT0308
MRAMRA_0304
MTFTBFG_10302
MTBTBMG_00300
MTKTBSG_00304
MTZTBXG_000301
MTGMRGA327_01895
MTIMRGA423_01900
MTECCDC5079_0274
MTURCFBS_0313
MTLCCDC5180_0273
MTOMTCTRI2_0302
MTDUDA_0295c
MTNERDMAN_0329
MTJJ112_01610
MTUBMT7199_0302
MTUCJ113_02165
MTUEJ114_01615
MTXM943_01550
MTUHI917_02110
MTULTBHG_00294
MTUTHKBT1_0313
MTUUHKBT2_0313
MTQHKBS1_0313
MBOBQ2027_MB0303C
MBBBCG_0335c
MBTJTY_0305
MBMBCGMEX_0305c
MBKK60_003170
MBXBCGT_0065
MAFMAF_02970
MMICRN08_0337
MCEMCAN_03041
MCQBN44_10339
MCVBN43_10334
MCXBN42_20021
MCZBN45_10328
MPAMAP_2118
MAOMAP4_1705
MAVIRC58_08520
MAVURE97_08520
MAVMAV_2058
MITOCO_20370
MIAOCU_20470
MIDMIP_02867
MYOOEM_18200
MCHIAN480_10395
MIROCQ_19040
MMALCKJ54_08850
MMANMMAN_20190 MMAN_35870(stf0)
MSAMycsm_00285
MMCMmcs_0389
MKMMkms_0398
MJLMjls_0377
MMIMMAR_4255
MMAEMMARE11_40680
MMMW7S_09550
MLIMULP_04434
MKNMKAN_07210
MYVG155_03115
MYEAB431_02465
MGOAFA91_02415
MHADB586_00830
MDXBTO20_32985
MSHGMSG_03818
MFJMFLOJ_48450
MSTOMSTO_52360
MSIMMSIM_38380
MSAKMSAS_21000
MKUI2456_20070
MGROFZ046_08530
MXEMYXE_45730(stf0)
MNVMNVI_20490
MPAGC0J29_23360
MGORH0P51_21545
MCOOMCOO_19370 MCOO_36480(stf0)
MBAIMB901379_03720
MSEOMSEO_21420
MPSEMPSD_43910
MHEKJMUB5695_04415(stf0)
MGAUMGALJ_48150
MLJMLAC_08090
MBRDMBRA_11800(stf0)
MSHJMSHI_03930
MDFK0O62_02935
MMAMK3U93_18295
MSENK3U95_03100
MPAEK0O64_02080
MSPGF6B93_02165
MOTLTS72_04005
MSMMSMEG_0630
MSGMSMEI_0614
MSBLJ00_03130
MSNLI99_03130
MSHLI98_03130
MNED174_03860
MYNMyAD_03775
MFTXA26_05680
MPHLMPHLCCUG_04751
MVQMYVA_0396
MLLB1R94_02520
MRHMycrhN_1406
MHASMHAS_04639(stf0)
MCHTMCHIJ_31410(stf0)
MAUUNCTC10437_00387
MMAGMMAD_06530
MMORMMOR_00150 MMOR_00160 MMOR_61250
MAICMAIC_52030(stf0)
MTYMTOK_09500(stf0)
MPSCMPSYJ_05460
MARZMARA_34140
MGADMGAD_46920
MHEVMHEL_17650(stf0)
MSARMSAR_19950(stf0)
MANYMANY_44550
MAUBMAUB_37740(stf0)
MPHUMPHO_32720(stf0)
MMUCC1S78_001710
MMATMMAGJ_14750
MBOKMBOE_17610
MFGK6L26_28680
MSEIMSEDJ_17360
MFLVNCTC10271_04720
MABMAB_1546c
MMVMYCMA_10710
MABBMASS_1642
MABLMMASJCM_1566
MCHEBB28_08395
MIZBAB75_08380
MSTEMSTE_01538
MSAOMYCSP_06935
MSALDSM43276_01403
RHARHA1_ro01265
RERRER_01280
REYO5Y_00645
REBXU06_00660
RQIC1M55_00670
ROPROP_09850
ROAPd630_LPD05366
RHODAOT96_11230
RTMG4H71_08705
RKOJWS14_06545
GBRGbro_1563
GPOGPOL_c14170
GORKTR9_1484
GTABCM27_08230
GRUGCWB2_07780
GOMD7316_03681(stf0)
GAMGII34_06840
GPDGII33_06300
GJIH1R19_07610
GOILK459_03005
SPINKV203_06105
TPRTpau_3332
TSMASU32_04780
SDXC4B68_38970
SRKFGW37_03665
CFLCfla_3588
MIKFOE78_06760 FOE78_18310
MICGGJV80_11070
AFSAFR_20265
PLKCIK06_25695
PSUUPsuf_048710
NHYJQS43_16225
RXYRxyl_2350
AYMYM304_42100
EUZDVS28_a0141
CHONNIES4102_26330
CYLAA637_08080
HAOPCC7418_2773
PLPPle7327_1126
SCSSta7437_2176
STANSTA3757_24270
KBSEPA93_34475
DPDDeipe_2186
TRATrad_0294
SOAG3M56_000720 G3M56_002420
GAUGAU_2069
RHOZGXP67_29085
 » show all
Reference
1  [PMID:15258569]
  Authors
Mougous JD, Petzold CJ, Senaratne RH, Lee DH, Akey DL, Lin FL, Munchel SE, Pratt MR, Riley LW, Leary JA, Berger JM, Bertozzi CR
  Title
Identification, function and structure of the mycobacterial sulfotransferase that initiates sulfolipid-1 biosynthesis.
  Journal
Nat Struct Mol Biol 11:721-9 (2004)
DOI:10.1038/nsmb802
  Sequence
Reference
2  [PMID:15866533]
  Authors
Pi N, Hoang MB, Gao H, Mougous JD, Bertozzi CR, Leary JA
  Title
Kinetic measurements and mechanism determination of Stf0 sulfotransferase using mass spectrometry.
  Journal
Anal Biochem 341:94-104 (2005)
DOI:10.1016/j.ab.2005.02.004
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.8.2.37
IUBMB Enzyme Nomenclature: 2.8.2.37
ExPASy - ENZYME nomenclature database: 2.8.2.37
BRENDA, the Enzyme Database: 2.8.2.37

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