KEGG ENZYME: 2.8.2.4

ENZYME: 2.8.2.4

Entry

EC 2.8.2.4                  Enzyme

Name

estrone sulfotransferase;
3'-phosphoadenylyl sulfate-estrone 3-sulfotransferase;
estrogen sulfotransferase;
estrogen sulphotransferase;
oestrogen sulphotransferase;
3'-phosphoadenylylsulfate:oestrone sulfotransferase;
3'-phosphoadenylyl-sulfate:estrone 3-sulfotransferase

Class

Transferases;
Transferring sulfur-containing groups;
Sulfotransferases

Sysname

3'-phosphoadenylyl-sulfate:estrone 3-sulfonotransferase

Reaction(IUBMB)

3'-phosphoadenylyl sulfate + estrone = adenosine 3',5'-bisphosphate + estrone 3-sulfate [RN:R02350]

Reaction(KEGG)

R02350

Substrate

3'-phosphoadenylyl sulfate [CPD:C00053];
estrone [CPD:C00468]

Product

adenosine 3',5'-bisphosphate [CPD:C00054];
estrone 3-sulfate [CPD:C02538]

History

EC 2.8.2.4 created 1965

Pathway

ec00140

Steroid hormone biosynthesis

ec01100

Metabolic pathways

Orthology

K01016

estrone sulfotransferase

Genes

HSA:	6783(SULT1E1)

PTR:	461284(SULT1E1)

PPS:	100972770(SULT1E1)

GGO:	101142110(SULT1E1)

PON:	100452192(SULT1E1)

NLE:	100600592(SULT1E1)

MCC:	708519(SULT1E1)

MCF:	102121142(SULT1E1)

MTHB:

126955143

CSAB:

103235726(SULT1E1)

CATY:

105596185(SULT1E1)

PANU:

101016288(SULT1E1)

TGE:	112624802(SULT1E1)

RRO:	104668687(SULT1E1)

RBB:	108521528(SULT1E1)

TFN:	117085531(SULT1E1)

PTEH:

111531123(SULT1E1)

CJC:	100409935(SULT1E1)

SBQ:	101033698(SULT1E1)

CSYR:

103272020

MMUR:

105883074(SULT1E1)

LCAT:

123624112

OGA:

100952573

MMU:	20860(Sult1e1)

MCAL:

110295280

MPAH:

110330635

RNO:	360268(Sult1e1)

MCOC:

116070590(Sult1e1)

MAUA:

101841791

PLEU:

114689639

MORG:

121460957

MFOT:

126506202

AAMP:

119827159

NGI:

103731093

HGL:	101715367(Sult1e1)

CPOC:

100135625(Sult1e1)

CCAN:

109681454

DORD:

105988511

DSP:

122106707

OCU:	100358708(SULT1E1)

OPI:	101525144(SULT1E1)

TUP:	102468843(SULT1E1)

CFA:

482182

CLUD:

112652199

VVP:

112923635

VLG:

121473601

AML:

100469041

UMR:

103656321

UAH:

113262557

UAR:

123786770

ELK:

111149178

LLV:

125093788

MPUF:

101691277(SULT1E1)

FCA:	101086305(SULT1E1)

PYU:	121034757(SULT1E1)

PBG:	122478832(SULT1E1)

LRUF:

124520995

PTG:	102969965(SULT1E1)

PPAD:

109278135(SULT1E1)

AJU:	106977022(SULT1E1)

HHV:

120244962

BTA:	280934(SULT1E1)

BOM:	102280512(SULT1E1)

BIU:

109560543

BBUB:

102397039(SULT1E1)

CHX:

102169846

OAS:

101120331

ODA:

120862209

CCAD:

122428210

SSC:	397052(SULT1E1)

CFR:	102520382(SULT1E1)

CBAI:

105080414(SULT1E1)

CDK:

105090956

VPC:

102525888

BACU:

103010557(SULT1E1)

LVE:	103078062(SULT1E1)

OOR:	101274097(SULT1E1)

DLE:	111168133(SULT1E1)

PCAD:

102983751(SULT1E1)

PSIU:

116753846(SULT1E1)

ECB:	100034106(SULT1E1) 102148009

EPZ:	103540583 103565618(SULT1E1)

EAI:	106838823 106838824

MYB:	102247493(SULT1E1)

MYD:	102756613(SULT1E1)

MMYO:

118652749

MLF:	102440853(SULT1E1)

MNA:

107541934

PKL:

118705644

HAI:

109377024

DRO:	112320054(SULT1E1)

SHON:

118982862(SULT1E1)

AJM:

119047536

PDIC:

114492564

PHAS:

123831255

MMF:

118625197

RFQ:

117021956

PALE:

102897942

PGIG:

120588161

PVP:

105292452

RAY:	107499314(SULT1E1)

TOD:

119261101

SARA:

101558028

LAV:

100662296

TMU:	101342023 101351259

DNM:

101433001

OAA:	100081825(SULT1E1)

MGP:

100549463

ETL:

114062186

PADL:

103923454

XLA:	734332(sult1e1.L)

XTR:	733517(sult1e1)

NPR:

108785251

RTEM:

120917358

BBUF:

120980292

BGAR:

122920160

TNG:	GSTEN00033256G001

MALB:

109951122

RTP:

109912250

BBEL:

109463690

SPU:	100892539 115929599

APLC:

110978853 110983885 110983905 110985238

SKO:	100368200 100371187 100375253 102807042 102809687

DER:

6552414

DSI:	Dsimw501_GD18598(Dsim_GD18598)

DYA:	Dyak_GE25933

DSR:

110186868

DPO:

4800360

DPE:

6595289

DMN:

108155290

DWI:	111518713 6649898

DMO:	Dmoj_GI22042

DAZ:

108621387

DNV:

108659227

DHE:

111594805

DVI:

6631266

MDE:	101888261 101892316 101893174 101895641

LCQ:	111677254 111689434 111689438

AGA:	AgaP_AGAP004498 AgaP_AGAP012647 AgaP_AGAP012648 AgaP_AGAP012696

ACOZ:

120950879 120959728

AAG:	5565034 5567887

AALB:

109400398

CQU:	CpipJ_CPIJ012993

CPII:

120427894

AME:	411376 412996

BIM:	100746578 100747712

BTER:

100642559 100646485

CCAL:

108627339 113465059

OBB:

114875086

SOC:

105200244

MPHA:

105832269 105839454

AEC:

105149482

ACEP:

105626709

PBAR:

105432926

HST:

105181786

CFO:

105253437

LHU:

105675308

OBO:

105278997

PCF:

106784263

MDL:

103570656

TCA:	103312936 655384

DPA:

109533704

NVL:	108566639 108566640 108566641 108566643

BMOR:

101741032 101742708 733034(St1)

BMAN:

114245386 114247339

DPL:	KGM_206769

ZCE:

119837791

HAW:

110373586

TNL:	113491743 113495356 113507786

PXY:

105389741

API:

100164639

DNX:

107173744

AGS:

114128149

RMD:

113549801

BTAB:

109035036 109038979 109038980 109038981 109039126

CLEC:

106661186 106662801 106670929 106672175

PHU:	Phum_PHUM307230

ZNE:	110838561 110841328

FCD:

110848377

DPX:	DAPPUDRAFT_201267 DAPPUDRAFT_237515 DAPPUDRAFT_301363 DAPPUDRAFT_302543 DAPPUDRAFT_310616 DAPPUDRAFT_313752 DAPPUDRAFT_55135 DAPPUDRAFT_93396

DMK:

116926766

PVM:	113802181 113808176 113814200

PJA:

122262653

PCHN:

125027324 125027612 125029139 125036600

HAME:

121878455

PCLA:

123747866 123760313

PTRU:

123500104

LSM:

121120852

PPOI:

119094028 119094323

ISC:	IscW_ISCW000674 IscW_ISCW007336 IscW_ISCW011823 IscW_ISCW013239 IscW_ISCW013748

DSV:

119464063

RMP:

119164368

CSCU:

111622620 111628361

PTEP:

107445123 107445125 107446038 107446039 107455386 107457257 122268226 122268532

SDM:	118180464 118191492 118195024

HRO:	HELRODRAFT_65652

LGI:	LOTGIDRAFT_226173

HRF:	124125485 124125487 124150218

HRJ:	124261046 124263128 124263168 124282188 124282334 124282335 124282342 124282354 124282361 124291516

CRG:	105326134 105336593 105343440 117683169

MYI:	110452573 110452579 110465272

PMAX:

117332922 117335806

MMER:

123531886 123534060

OBI:	106868267 106879495 106884083 106884084

OSN:	115209727 115209760 115209814 115209838 115209856 115209910 115232577

LAK:	106151325 106161652

OVI:	T265_06991

EPA:

110244997

ADF:	107328966 107355123 107355132 107357481

AMIL:

114950307 114963216 114964770 114966151 114966154 114966166 114975156

DGT:	114528127 114529086 114529087 114529088

OBR:

102720016

ATS:

109773486

MBR:	MONBRDRAFT_22879

FCY:	FRACYDRAFT_181614(CHST1)

AAF:	AURANDRAFT_64972

GTT:	GUITHDRAFT_58356

MAH:	MEALZ_0057

BON:	A361_11840

SYL:	AWQ21_10265

HHG:	XM38_025170

GLP:	Glo7428_1256

MPK:

VL20_763

CAN:	Cyan10605_1079

RIV:	Riv7116_0477

MMH:

Mmah_0085

» show all

Reference

1 [PMID:4965224]

Authors

Adams JB, Poulos A.

Title

Enzymic synthesis of steroid sulphates. 3. Isolation and properties of estrogen sulphotransferase of bovine adrenal glands.

Journal

Biochim Biophys Acta 146:493-508 (1967)
DOI:10.1016/0005-2744(67)90233-1

Reference

2 [PMID:903358]

Authors

Rozhin J, Huo A, Zemlicka J, Brooks SC.

Title

Studies on bovine adrenal estrogen sulfotransferase. Inhibition and possible involvement of adenine-estrogen stacking.

Journal

J Biol Chem 252:7214-20 (1977)

Reference

3 [PMID:4473218]

Authors

Adams JB, Ellyard RK, Low J.

Title

Enzymic synthesis of steroid sulphates. IX. Physical and chemical properties of purified oestrogen sulphotransferase from bovine adrenal glands, the nature of its isoenzymic forms and a proposed model to explain its wave-like kinetics.

Journal

Biochim Biophys Acta 370:160-88 (1974)
DOI:10.1016/0005-2744(74)90042-4

Other DBs

ExplorEnz - The Enzyme Database:

2.8.2.4

IUBMB Enzyme Nomenclature:

2.8.2.4

ExPASy - ENZYME nomenclature database:

2.8.2.4

BRENDA, the Enzyme Database:

2.8.2.4

CAS:

9026-06-6

DBGET integrated database retrieval system