KEGG ENZYME: 2.8.2.4

ENZYME: 2.8.2.4

Entry

EC 2.8.2.4 Enzyme

Name

estrone sulfotransferase;
3'-phosphoadenylyl sulfate-estrone 3-sulfotransferase;
estrogen sulfotransferase;
estrogen sulphotransferase;
oestrogen sulphotransferase;
3'-phosphoadenylylsulfate:oestrone sulfotransferase;
3'-phosphoadenylyl-sulfate:estrone 3-sulfotransferase

Class

Transferases;
Transferring sulfur-containing groups;
Sulfotransferases

Sysname

3'-phosphoadenylyl-sulfate:estrone 3-sulfonotransferase

Reaction(IUBMB)

3'-phosphoadenylyl sulfate + estrone = adenosine 3',5'-bisphosphate + estrone 3-sulfate [RN:R02350]

Reaction(KEGG)

R02350

Substrate

3'-phosphoadenylyl sulfate [CPD:C00053];
estrone [CPD:C00468]

Product

adenosine 3',5'-bisphosphate [CPD:C00054];
estrone 3-sulfate [CPD:C02538]

History

EC 2.8.2.4 created 1965

Pathway

ec00140

Steroid hormone biosynthesis

Orthology

K01016

estrone sulfotransferase

Genes

HSA:	6783(SULT1E1)

PTR:	461284(SULT1E1)

PPS:	100972770(SULT1E1)

GGO:	101142110(SULT1E1)

PON:	100452192(SULT1E1)

NLE:	100600592(SULT1E1)

MCC:	708519(SULT1E1)

MCF:	102121142(SULT1E1)

CSAB:

103235726(SULT1E1)

RRO:	104668687(SULT1E1)

RBB:	108521528(SULT1E1)

CJC:	100409935(SULT1E1)

SBQ:	101033698(SULT1E1)

MMU:	20860(Sult1e1)

MCAL:

110295280

MPAH:

110330635

RNO:	360268(Sult1e1)

NGI:

103731093

HGL:	101715367(Sult1e1)

CCAN:

109681454

OCU:	100358708(SULT1E1)

TUP:	102468843(SULT1E1)

CFA:

VVP:

AML:

UMR:

UAH:

ELK:

FCA:	101086305(SULT1E1)

PTG:	102969965(SULT1E1)

PPAD:

109278135(SULT1E1)

AJU:	106977022(SULT1E1)

BTA:	280934(SULT1E1)

BOM:	102280512(SULT1E1)

BIU:

109560543

BBUB:

102397039(SULT1E1)

CHX:	102169846(SULT1E1)

OAS:

101120331

SSC:	397052(SULT1E1)

CFR:	102520382(SULT1E1)

CDK:

105090956

BACU:

103010557(SULT1E1)

LVE:	103078062(SULT1E1)

OOR:	101274097(SULT1E1)

DLE:	111168133(SULT1E1)

PCAD:

102983751(SULT1E1)

ECB:	100034106(SULT1E1) 102148009

EPZ:	103540583 103565618(SULT1E1)

EAI:	106838823 106838824

MYB:	102247493(SULT1E1)

MYD:	102756613(SULT1E1)

MNA:

107541934

HAI:

109377024

DRO:	112320054(SULT1E1)

PALE:

102897942

RAY:	107499314(SULT1E1)

LAV:

100662296

TMU:	101342023 101351259

OAA:	100081825(SULT1E1)

MGP:

100549463

ETL:

114062186

PADL:

103923454

XLA:	734332(sult1e1.L)

XTR:	733517(sult1e1)

NPR:

108785251

TNG:	GSTEN00033256G001

MALB:

109951122

RTP:

109912250

SPU:	100892539 115929599

APLC:

110978853 110983885 110983905 110985238

SKO:	100368200 100371187 100375253 102807042 102809687

DER:

6552414

DSI:	Dsimw501_GD18598(Dsim_GD18598)

DYA:	Dyak_GE25933

DSR:

110186868

DPO:	Dpse_GA14114

DPE:

6595289

DMN:

108155290

DWI:	111518713 6649898

DGR:	Dgri_GH19934

DMO:	Dmoj_GI22042

DAZ:

DNV:

DHE:

DVI:

MDE:	101888261 101892316 101893174 101895641

LCQ:	111677254 111689434 111689438

AGA:	AgaP_AGAP004498 AgaP_AGAP012647 AgaP_AGAP012648 AgaP_AGAP012696

AAG:	5565034 5567887

AALB:

109400398

CQU:	CpipJ_CPIJ012993

AME:	411376 412996

BIM:	100746578 100747712

BTER:

CCAL:

OBB:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

HST:

CFO:

LHU:

OBO:

PCF:

MDL:

TCA:	103312936 655384

DPA:

109533704

NVL:	108566639 108566640 108566641 108566643

BMOR:

101741032 101742708 692551(Sult) 733034(St1)

BMAN:

114245386 114245422 114247339

DPL:	KGM_206769 KGM_210845

PRAP:

110996910 110997266 111000199 111001531 111001535

HAW:	110372049 110372608 110373586

TNL:	113491743 113494895 113495356 113507786

PXY:

API:

DNX:

AGS:

RMD:

BTAB:

109035036 109038979 109038980 109038981 109039126

CLEC:

106661186 106662801 106670929 106672175

PHU:	Phum_PHUM307230

ZNE:	110838561 110841328

FCD:

110848377

DPX:	DAPPUDRAFT_201267 DAPPUDRAFT_237515 DAPPUDRAFT_301363 DAPPUDRAFT_302543 DAPPUDRAFT_310616 DAPPUDRAFT_313752 DAPPUDRAFT_55135 DAPPUDRAFT_93396

PVM:	113802181 113808176 113814200

ISC:	IscW_ISCW000674 IscW_ISCW007336 IscW_ISCW011823 IscW_ISCW013239 IscW_ISCW013748

CSCU:

111622620 111628361

PTEP:

107445123 107445124 107445125 107446038 107446039 107450320 107455386 107457257

HRO:	HELRODRAFT_65652

LGI:	LOTGIDRAFT_226173

CRG:	105326134 105336204 105343440 105347750 105348911

MYI:	110452573 110452579 110465272

OBI:	106868267 106879495 106884083 106884084

LAK:	106151325 106161652

OVI:	T265_06991

EPA:

110244997

ADF:	107328966 107355123 107355132 107357481

AMIL:

114950307 114963216 114964770 114966151 114966154 114966166 114975156

DGT:	114528127 114529086 114529087 114529088

OBR:

102720016

ATS:

109773486

MBR:	MONBRDRAFT_22879

FCY:	FRACYDRAFT_181614(CHST1)

AAF:	AURANDRAFT_64972

GTT:	GUITHDRAFT_58356

MAH:	MEALZ_0057

BON:	A361_11840

SYL:	AWQ21_10265

HHG:	XM38_025170

GLP:	Glo7428_1256

MPK:

VL20_763

CAN:	Cyan10605_1079

RIV:	Riv7116_0477

MMH:

Mmah_0085

» show all

Reference

1 [PMID:4965224]

Authors

Adams JB, Poulos A.

Title

Enzymic synthesis of steroid sulphates. 3. Isolation and properties of estrogen sulphotransferase of bovine adrenal glands.

Journal

Biochim Biophys Acta 146:493-508 (1967)
DOI:10.1016/0005-2744(67)90233-1

Reference

2 [PMID:903358]

Authors

Rozhin J, Huo A, Zemlicka J, Brooks SC.

Title

Studies on bovine adrenal estrogen sulfotransferase. Inhibition and possible involvement of adenine-estrogen stacking.

Journal

J Biol Chem 252:7214-20 (1977)

Reference

3 [PMID:4473218]

Authors

Adams JB, Ellyard RK, Low J.

Title

Enzymic synthesis of steroid sulphates. IX. Physical and chemical properties of purified oestrogen sulphotransferase from bovine adrenal glands, the nature of its isoenzymic forms and a proposed model to explain its wave-like kinetics.

Journal

Biochim Biophys Acta 370:160-88 (1974)
DOI:10.1016/0005-2744(74)90042-4

Other DBs

ExplorEnz - The Enzyme Database:

2.8.2.4

IUBMB Enzyme Nomenclature:

2.8.2.4

ExPASy - ENZYME nomenclature database:

2.8.2.4

BRENDA, the Enzyme Database:

2.8.2.4

CAS:

9026-06-6

DBGET integrated database retrieval system