KEGG   ENZYME: 2.8.3.17Help
Entry
EC 2.8.3.17                 Enzyme                                 

Name
cinnamoyl-CoA:phenyllactate CoA-transferase;
FldA
Class
Transferases;
Transferring sulfur-containing groups;
CoA-transferases
BRITE hierarchy
Sysname
(E)-cinnamoyl-CoA:(R)-phenyllactate CoA-transferase
Reaction(IUBMB)
(E)-cinnamoyl-CoA + (R)-phenyllactate = (E)-cinnamate + (R)-phenyllactyl-CoA [RN:R07796]
Reaction(KEGG)
Substrate
(E)-cinnamoyl-CoA [CPD:C16256];
(R)-phenyllactate [CPD:C05607]
Product
(E)-cinnamate [CPD:C00423];
(R)-phenyllactyl-CoA [CPD:C16257]
Comment
3-Phenylproprionate is a better CoA acceptor than (R)-phenyllactate in vitro. The enzyme from Clostridium sporogenes is specific for derivatives of 3-phenylpropionate and 4-phenylbutyrate.
History
EC 2.8.3.17 created 2003
Pathway
ec00960  Tropane, piperidine and pyridine alkaloid biosynthesis
Orthology
K13607  cinnamoyl-CoA:phenyllactate CoA-transferase
Genes
CBO: CBO3292(fldA)
CBA: CLB_3348(fldA)
CBH: CLC_3234(fldA)
CBY: CLM_3725(fldA)
CBL: CLK_2708(fldA)
CBB: CLD_1231(fldA)
CBI: CLJ_B3572(fldA)
CBF: CLI_3462(fldA)
CBM: CBF_3444(fldA)
CBJ: H04402_03377
CLD: CLSPO_c34120(fldA)
 » show all
Taxonomy
Reference
1  [PMID:10849007]
  Authors
Dickert S, Pierik AJ, Linder D, Buckel W.
  Title
The involvement of coenzyme A esters in the dehydration of (R)-phenyllactate to (E)-cinnamate by Clostridium sporogenes.
  Journal
Eur J Biochem 267:3874-84 (2000)
DOI:10.1046/j.1432-1327.2000.01427.x
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.8.3.17
IUBMB Enzyme Nomenclature: 2.8.3.17
ExPASy - ENZYME nomenclature database: 2.8.3.17
BRENDA, the Enzyme Database: 2.8.3.17
CAS: 289682-21-9

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