KEGG ENZYME: 2.8.3.20

ENZYME: 2.8.3.20

Entry

EC 2.8.3.20                 Enzyme

Name

succinyl-CoA---D-citramalate CoA-transferase;
Sct

Class

Transferases;
Transferring sulfur-containing groups;
CoA-transferases

Sysname

succinyl-CoA:(R)-citramalate CoA-transferase

Reaction(IUBMB)

(1) succinyl-CoA + (R)-citramalate = succinate + (R)-citramalyl-CoA [RN:R10640];
(2) succinyl-CoA + (R)-malate = succinate + (R)-malyl-CoA [RN:R10641]

Reaction(KEGG)

R10640 R10641

Substrate

succinyl-CoA [CPD:C00091];
(R)-citramalate [CPD:C02612];
(R)-malate [CPD:C00497]

Product

succinate [CPD:C00042];
(R)-citramalyl-CoA [CPD:C20746];
(R)-malyl-CoA [CPD:C20747]

Comment

The enzyme, purified from the bacterium Clostridium tetanomorphum, can also accept itaconate as acceptor, with lower efficiency.

History

EC 2.8.3.20 created 2014

Orthology

K18313

succinyl-CoA---D-citramalate CoA-transferase

Genes

MIND:

mvi_23440

AUB:	LXB15_15075

TMD:	KUV46_03885

PMAU:

CP157_00736(smtA)

SMUC:

JL100_031925

SROE:

JL101_032040

CFIR:

NAF01_12460

VIK:	KFZ58_15125

SCIA:

HUG15_13375 HUG15_20970

RMF:	D5E69_19650

ADAU:

NZD86_00465

CMIC:

caldi_00880

AACX:

DEACI_3327

ETM:	CE91St48_09760

NIE:	KV110_07875

NHU:	H0264_26070

NYA:	LTV02_12155

RGO:	KYT97_04195

SSOI:

I1A49_43075

YIA:	LO772_09555

NCX:	Nocox_12490(bbsF2)

DVC:	Dvina_12720

DAUR:

Daura_34785

DMAT:

Dmats_12285

RXY:

Rxyl_1698

RRS:	RoseRS_0050

RCA:

Rcas_3495

CAU:

Caur_2266

CHL:	Chy400_2439

CAG:

Cagg_3093

STI:

Sthe_0006

» show all

Reference

1 [PMID:16952935]

Authors

Friedmann S, Alber BE, Fuchs G

Title

Properties of succinyl-coenzyme A:D-citramalate coenzyme A transferase and its role in the autotrophic 3-hydroxypropionate cycle of Chloroflexus aurantiacus.

Journal

J Bacteriol 188:6460-8 (2006)
DOI:10.1128/JB.00659-06

Sequence

[cau:Caur_2266]

Other DBs

ExplorEnz - The Enzyme Database:

2.8.3.20

IUBMB Enzyme Nomenclature:

2.8.3.20

ExPASy - ENZYME nomenclature database:

2.8.3.20

BRENDA, the Enzyme Database:

2.8.3.20

All links

Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (3)   
   KEGG REACTION (2)   
   KEGG RCLASS (1)   
Gene (33)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (32)   
Protein sequence (39)   
   UniProt (38)   
   SWISS-PROT (1)   
DNA sequence (29)   
   GenBank (15)   
   EMBL (14)   
Protein domain (3)   
   InterPro (3)   
All databases (113)   

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