KEGG   ENZYME: 2.8.3.23Help
Entry
EC 2.8.3.23                 Enzyme                                 

Name
caffeate CoA-transferase;
CarA
Class
Transferases;
Transferring sulfur-containing groups;
CoA-transferases
BRITE hierarchy
Sysname
3-(3,4-dihydroxyphenyl)propanoyl-CoA:(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate CoA-transferase
Reaction(IUBMB)
3-(3,4-dihydroxyphenyl)propanoyl-CoA + (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate = 3-(3,4-dihydroxyphenyl)propanoate + (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl-CoA [RN:R11206]
Reaction(KEGG)
Substrate
3-(3,4-dihydroxyphenyl)propanoyl-CoA [CPD:C21175];
(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate [CPD:C01197]
Product
3-(3,4-dihydroxyphenyl)propanoate [CPD:C10447];
(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl-CoA [CPD:C00323]
Comment
The enzyme, isolated from the bacterium Acetobacterium woodii, catalyses an energy-saving CoA loop for caffeate activation. In addition to caffeate, the enzyme can utilize 4-coumarate or ferulate as CoA acceptor.
History
EC 2.8.3.23 created 2015
Reference
1  [PMID:23315745]
  Authors
Hess V, Gonzalez JM, Parthasarathy A, Buckel W, Muller V
  Title
Caffeate respiration in the acetogenic bacterium Acetobacterium woodii: a coenzyme A loop saves energy for caffeate activation.
  Journal
Appl Environ Microbiol 79:1942-7 (2013)
DOI:10.1128/AEM.03604-12
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.8.3.23
IUBMB Enzyme Nomenclature: 2.8.3.23
ExPASy - ENZYME nomenclature database: 2.8.3.23
BRENDA, the Enzyme Database: 2.8.3.23

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