KEGG   ENZYME: 3.1.1.110
Entry
EC 3.1.1.110                Enzyme                                 
Name
xylono-1,5-lactonase;
xylC (gene name);
D-xylono-1,5-lactone lactonase
Class
Hydrolases;
Acting on ester bonds;
Carboxylic-ester hydrolases
Sysname
D-xylono-1,5-lactone lactonohydrolase
Reaction(IUBMB)
D-xylono-1,5-lactone + H2O = D-xylonate [RN:R02427]
Reaction(KEGG)
R02427
Substrate
D-xylono-1,5-lactone [CPD:C02266];
H2O [CPD:C00001]
Product
D-xylonate [CPD:C00502]
Comment
The enzyme, found in bacteria, participates in the degradation of D-xylose. cf. EC 3.1.1.68, xylono-1,4-lactonase.
History
EC 3.1.1.110 created 2019
Pathway
ec00040  Pentose and glucuronate interconversions
ec01100  Metabolic pathways
Orthology
K14274  xylono-1,5-lactonase
Genes
SAVIJYB87_15485
PDJD0907_16170
ALRDS731_20350
APELCA267_011000
SALKFBQ74_03155
LALAT746_16735
SAGAM5M_11590
MTHDA3224_13600
MAGAMag101_00660
CSACsal_0453 Csal_1727
HCAMI4484_06145
HSXHNO51_05810
HSVHNO53_06500
HTXEKK97_06850
RPIRpic_4078
RPFRpic12D_4190
RMNTK49_20875
CBWRR42_s1947
CCUPBKK81_23070
CUPBKK80_33215
CUUBKK79_24105
BSAVWS86_09455
BGLbglu_1g22110
BGUKS03_3045
BGPBGL_1c15160
BPLAbpln_1g14880
BXEBxe_C1362
BXBDR64_8448
BGEBC1002_6311
PSPWBJG93_31540
PACPFAZ97_29030
RSBRS694_18450
RHYRD110_12070
RHGEXZ61_19560
AAVAave_2259
AAAAcav_2881
ACKC380_10510
ACIOEAG14_03845
VAPVapar_1040
VPEVarpa_1109
VPDVAPA_1c10930
VBOCKY39_05160
VAMC4F17_13990
HPSEHPF_09080(araB2)
STHMIS481_17800
PBHAAW51_0546
HHTF506_05380
HEEhmeg3_16530
MTIMDIR46_22465
MASYDPH57_11380 DPH57_12555
MANCIV454_19205
MFYHH212_20325
MASZC9I28_09445 C9I28_10615
MALIEYF70_20030 EYF70_21150
MUMFCL38_27880 FCL38_29050
MFLAGO485_23500 GO485_24790
MPLIE1742_23110 E1742_24295
DUGHH213_05140 HH213_29255
RGUA4W93_11075
MXAMXAN_3250
MYMA176_003701
MFULILAB_24030
MMASMYMAC_003208
MRDMrad2831_1323
MORMOC_1680
MPHYMCBMB27_00978
METXA3862_24210
MMESMMSR116_17520
BBARRHAL1_00794
MCGGL4_0247
CCRCC_0820
CCSCCNA_00863(xylC)
CAKCaul_4002
CSECseg_3555
CHQAQ619_03675
CFHC1707_01240
CAUFCSW63_19055
CAULKCG34_25080
PZUPHZ_c2467(gnl)
BSBBresu_2946
BRGA4249_02075
BRLBZG35_07250
BVCCEP68_01690
BMEDGYM46_01945
BPONIFE19_15295
BGOEIFJ75_11095
BVITJIP62_01270
BALBM8231_01130
AEXAstex_1077 Astex_1910
TSVDSM104635_01758(araB_1) DSM104635_03103(araB_2)
NPPPP1Y_Mpl1116
NREBES08_06910 BES08_15260 BES08_20250
NOVTQ38_020680 TQ38_022630
NOTC7W88_19795
NORFA702_20275
NDRHT578_14240 HT578_16920
SALSala_0747
SPHQBWQ93_10700
SPHMG432_06495 G432_09685 G432_12865
STAXMC45_10355
SPHITS85_11215
SSANNX02_17665
SNJA7E77_09050
SMYBJP26_04940
SPANAWL63_01160
SKRBRX40_02255
SPLMBXU08_08395
SPLKAV944_00250
SPHCCVN68_09050
SPHFDM480_08655
SPAUDRN02_015795
SDHH9L15_10750
SPAPH3Z74_12340
SPIIG7077_03990
SSING7078_02950
SSAUH8M03_07325
SARIH5J25_14765
SSUAFPZ54_11745 FPZ54_13715
SBINSBA_ch1_01320 SBA_ch1_21010(xylC)
SAERNEF64_10885
SMORLHA26_13735
SQONMP03_08205
SJPSJA_C1-12860
SINBSIDU_07860
SYBTZ53_20795 TZ53_22170
SPMIK663_01025
SPHBEP837_02111(araB)
SPHRBSY17_1048 BSY17_2829
SPHTK426_04615
SHYDCJD35_07435
SYAA6768_03420 A6768_17790
SPYGYGS_C1P2072 YGS_C2P1109
SUFLFIL70_09980 FIL70_11325
SBARH5V43_07695 H5V43_09805 H5V43_16805
SAMISAMIE_1004010
BLASBSY18_1344
BFWB5J99_16095
SPZRG5C33_10770
SPHSETR14_15940
SANDH3309_08365
POQKZX46_04590 KZX46_07845
PMEAKTC28_03315 KTC28_06930
AAYWYH_02214(araB)
ADOA6F68_00103(araB_1)
CMANA9D14_07170
QCINCF85_07990
ERFFIU90_14250(araB)
POTE2E27_07760
GOXGOX1793
GOHB932_0278
GOYGLS_c19130
GALA0U94_03065
GTIFXF46_09130
GSPIGS75_10355
GFAMKW11_08995
GDIGDI2179
GDJGdia_0398
GXYGLX_25580
GXLH845_501
KNAB0W47_12885
KEUS101446_02891
KSCCD178_00518(araB)
KREGWK63_03420
AACEA0U92_01990
ABGAsbog_01907
KBAA0U89_03250
NCHA0U93_10730
NTND5366_05805
NEHE3E11_07060
SSAME3D00_07980
SWFE3E12_06380
BOBGN304_03130
BOMBGT348_02685
LCKHN018_08005
KHAIFJ82_12705
PARZDTQ13_07390
AZLAZL_e03640
ALIAZOLI_p50378
ABSAZOBR_p440161
ABQABAZ39_31210 ABAZ39_31600
ABFAMK58_27055 AMK58_27390
ATIAL072_30995
AHUA6A40_14235
AZTTSH58p_18660 TSH58p_21365
AZMDM194_26430
AZZDEW08_21995
AOZHUE56_23210
NAOY958_17430
NCBC0V82_25355
ACUAtc_2721
ACZAcaty_c2569
MVTI6J10_08025
NANOG5V58_18995
 » show all
Reference
1  [PMID:22709678]
  Authors
Toivari M, Nygard Y, Kumpula EP, Vehkomaki ML, Bencina M, Valkonen M, Maaheimo H, Andberg M, Koivula A, Ruohonen L, Penttila M, Wiebe MG
  Title
Metabolic engineering of Saccharomyces cerevisiae for bioconversion of D-xylose to D-xylonate.
  Journal
Metab Eng 14:427-36 (2012)
DOI:10.1016/j.ymben.2012.03.002
  Sequence
[ccr:CC_0820]
Reference
2  [PMID:25073011]
  Authors
Nygard Y, Maaheimo H, Mojzita D, Toivari M, Wiebe M, Resnekov O, Gustavo Pesce C, Ruohonen L, Penttila M
  Title
Single cell and in vivo analyses elucidate the effect of xylC lactonase during production of D-xylonate in Saccharomyces cerevisiae.
  Journal
Metab Eng 25:238-47 (2014)
DOI:10.1016/j.ymben.2014.07.005
Other DBs
ExplorEnz - The Enzyme Database: 3.1.1.110
IUBMB Enzyme Nomenclature: 3.1.1.110
ExPASy - ENZYME nomenclature database: 3.1.1.110
BRENDA, the Enzyme Database: 3.1.1.110

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