| Entry |
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| Name |
feruloyl esterase;
ferulic acid esterase;
hydroxycinnamoyl esterase;
hemicellulase accessory enzyme;
FAE-III;
cinnamoyl ester hydrolase;
FAEA;
cinnAE;
FAE-I;
FAE-II
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| Class |
Hydrolases;
Acting on ester bonds;
Carboxylic-ester hydrolases
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| Sysname |
4-hydroxy-3-methoxycinnamoyl-sugar hydrolase
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| Reaction(IUBMB) |
feruloyl-polysaccharide + H2O = ferulate + polysaccharide [RN: R07292]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
Catalyses the hydrolysis of the 4-hydroxy-3-methoxycinnamoyl (feruloyl) group from an esterified sugar, which is usually arabinose in "natural" substrates. p-Nitrophenol acetate and methyl ferulate are poorer substrates. All microbial ferulate esterases are secreted into the culture medium. They are sometimes called hemicellulase accessory enzymes, since they help xylanases and pectinases to break down plant cell wall hemicellulose.
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| History |
EC 3.1.1.73 created 2000
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| Orthology |
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| Genes |
» show all
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| Reference |
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| Authors |
Faulds CB, Williamson G. |
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| Title |
The purification and characterization of 4-hydroxy-3-methoxycinnamic (ferulic) acid esterase from Streptomyces olivochromogenes. |
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| Journal |
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| Reference |
2 |
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| Authors |
Faulds, C.B. and Williamson, G. |
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| Title |
Purification and characterisation of a ferulic acid esterase (FAE-III) from Aspergillus niger. Specificity for the phenolic moiety and binding to microcrystalline cellulose. |
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| Journal |
Microbiology 140:779-787 (1994) |
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| Reference |
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| Authors |
Kroon PA, Faulds CB, Williamson G. |
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| Title |
Purification and characterization of a novel esterase induced by growth of Aspergillus niger on sugar-beet pulp. |
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| Journal |
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| Sequence |
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| Reference |
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| Authors |
de Vries RP, Michelsen B, Poulsen CH, Kroon PA, van den Heuvel RH, Faulds CB, Williamson G, van den Hombergh JP, Visser J |
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| Title |
The faeA genes from Aspergillus niger and Aspergillus tubingensis encode ferulic acid esterases involved in degradation of complex cell wall polysaccharides. |
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| Journal |
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| Sequence |
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| Reference |
5 |
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| Authors |
Castanares, A., Mccrae, S.I. and Wood, T.M. |
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| Title |
Purification and properties of a feruloyl/p-coumaroyl esterase from the fungus Penicillium pinophilum. |
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| Journal |
Enzyme Microbiol Technol 14:875-884 (1992) |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 3.1.1.73 |
| ExPASy - ENZYME nomenclature database: | 3.1.1.73 |
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