KEGG   ENZYME: 3.1.1.8Help
Entry
EC 3.1.1.8                  Enzyme                                 

Name
cholinesterase;
pseudocholinesterase;
butyrylcholine esterase;
non-specific cholinesterase;
choline esterase II (unspecific);
benzoylcholinesterase;
choline esterase;
butyrylcholinesterase;
propionylcholinesterase;
BtChoEase
Class
Hydrolases;
Acting on ester bonds;
Carboxylic-ester hydrolases
BRITE hierarchy
Sysname
acylcholine acylhydrolase
Reaction(IUBMB)
an acylcholine + H2O = choline + a carboxylate [RN:R01029]
Reaction(KEGG)
Substrate
acylcholine [CPD:C01777];
H2O [CPD:C00001]
Product
choline [CPD:C00114];
carboxylate [CPD:C00060]
Comment
Acts on a variety of choline esters and a few other compounds.
History
EC 3.1.1.8 created 1961
Orthology
K01050  cholinesterase
Genes
HSA: 590(BCHE)
PTR: 460830(BCHE)
PPS: 100972372(BCHE)
GGO: 101135975(BCHE)
PON: 100174585(BCHE)
NLE: 100586324(BCHE)
MCC: 700484(BCHE)
MCF: 102130167(BCHE)
CSAB: 103221309(BCHE)
RRO: 104655785(BCHE)
RBB: 108541031(BCHE)
CJC: 100409326(BCHE)
SBQ: 101029649(BCHE)
MMU: 12038(Bche)
RNO: 65036(Bche)
CGE: 100767789(Bche)
NGI: 103728609(Bche)
HGL: 101712877(Bche)
CCAN: 109679490(Bche)
OCU: 100338759(BCHE)
TUP: 102496968(BCHE)
CFA: 488143(BCHE)
AML: 100464904(BCHE)
UMR: 103664429(BCHE)
ORO: 101382195(BCHE)
FCA: 493960(BCHE)
PTG: 102952605(BCHE)
AJU: 106987452(BCHE)
BTA: 534616(BCHE)
BOM: 102267863(BCHE)
BIU: 109558593(BCHE)
PHD: 102328336(BCHE)
CHX: 102187168(BCHE)
OAS: 101102112(BCHE)
SSC: 100624138(BCHE)
CFR: 102523324(BCHE)
CDK: 105085977(BCHE)
BACU: 103011235(BCHE)
LVE: 103076485(BCHE)
OOR: 101285649(BCHE)
ECB: 100033901(BCHE)
EPZ: 103552042(BCHE)
EAI: 106842409(BCHE)
MYB: 102257140(BCHE)
MYD: 102753302(BCHE)
HAI: 109373265(BCHE)
RSS: 109449566(BCHE)
PALE: 102883546(BCHE)
LAV: 100666102(BCHE)
TMU: 101353513
MDO: 100618084(BCHE)
SHR: 100930262(BCHE)
OAA: 100074368(BCHE)
GGA: 395358(BCHE)
MGP: 100538485(BCHE)
CJO: 107318341(BCHE)
APLA: 101790679(BCHE)
ACYG: 106031959(BCHE)
TGU: 100229708(BCHE)
GFR: 102044616(BCHE)
FAB: 101808546(BCHE)
PHI: 102106247(BCHE)
PMAJ: 107209012(BCHE)
CCW: 104688062(BCHE)
FPG: 101918906(BCHE)
FCH: 102056322(BCHE)
CLV: 102095857(BCHE)
EGZ: 104133796(BCHE)
AAM: 106499612(BCHE)
ASN: 102386904(BCHE)
AMJ: 102575868(BCHE)
PSS: 102451430(BCHE)
CMY: 102946073(BCHE)
CPIC: 101939015(BCHE) 103307497
XTR: 100135377(bche) 100494295 100495889(bche)
NPR: 108798271 108802121(BCHE)
SRX: 107735268
SANH: 107660675
SGH: 107600247
AMEX: 103037776
NCC: 104958666
MZE: 101487581
OLA: 100529181(bche) 101169010
PRET: 103474418(bche)
NFU: 107396314
LCF: 108886340
HCQ: 109525520
BPEC: 110174478
SASA: 106613213
SFM: 108924671(bche) 108936474
CMK: 103176352(bche) 103179126
MDE: 101900490
FCD: 110844150
CEL: CELE_Y48B6A.8(ace-3)
CBR: CBG02828(Cbr-ace-3)
BMY: Bm1_46735
SHX: MS3_05322
ADF: 107337265
AQU: 100634023
SMIN: v1.2.027506.t1(symbB.v1.2.027506.t1)
PSF: PSE_1258
 » show all
Taxonomy
Reference
1
  Authors
Augustinsson, K.-B.
  Title
Cholinesterases. A study in comparative enzymology.
  Journal
Acta Physiol Scand 15, Suppl. 2 (1948)
Reference
2  [PMID:13638253]
  Authors
AUGUSTINSSON KB, OLSSON B.
  Title
Esterases in the milk and blood plasma of swine. I. Substrate specificity and electrophoresis studies.
  Journal
Biochem J 71:477-84 (1959)
Reference
3  [PMID:13032058]
  Authors
KOELLE GB.
  Title
Cholinesterases of the tissues and sera of rabbits.
  Journal
Biochem J 53:217-26 (1953)
Reference
4  [PMID:14885021]
  Authors
NACHMANSOHN D, WILSON IB.
  Title
The enzymic hydrolysis and synthesis of acetylcholine.
  Journal
Adv Enzymol Relat Subj Biochem 12:259-339 (1951)
Reference
5
  Authors
Sawyer, C.H.
  Title
Hydrolysis of choline esters by liver.
  Journal
Science 101:385-386 (1945)
Reference
6  [PMID:16747753]
  Authors
Strelitz F.
  Title
Studies on cholinesterase: 4. Purification of pseudo-cholinesterase from horse serum.
  Journal
Biochem J 38:86-8 (1944)
Other DBs
ExplorEnz - The Enzyme Database: 3.1.1.8
IUBMB Enzyme Nomenclature: 3.1.1.8
ExPASy - ENZYME nomenclature database: 3.1.1.8
BRENDA, the Enzyme Database: 3.1.1.8
CAS: 9001-08-5

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