KEGG   ENZYME: 3.1.1.94Help
Entry
EC 3.1.1.94                 Enzyme                                 

Name
versiconal hemiacetal acetate esterase;
VHA esterase
Class
Hydrolases;
Acting on ester bonds;
Carboxylic-ester hydrolases
BRITE hierarchy
Sysname
versiconal-hemiacetal-acetate O-acetylhydrolase
Reaction(IUBMB)
(1) versiconal hemiacetal acetate + H2O = versiconal + acetate [RN:R10401];
(2) versiconol acetate + H2O = versiconol + acetate [RN:R10398]
Reaction(KEGG)
Substrate
versiconal hemiacetal acetate [CPD:C20505];
H2O [CPD:C00001];
versiconol acetate [CPD:C20506]
Product
versiconal [CPD:C20507];
acetate [CPD:C00033];
versiconol [CPD:C20508]
Comment
Isolated from the mold Aspergillus parasiticus. Involved in a metabolic grid that leads to aflatoxin biosynthesis.
History
EC 3.1.1.94 created 2013
Pathway
ec00254  Aflatoxin biosynthesis
ec01100  Metabolic pathways
ec01130  Biosynthesis of antibiotics
Orthology
K17648  versiconal hemiacetal acetate esterase
Genes
PAN: PODANSg8561
MTM: MYCTH_54712
FGR: FGSG_09112
FVR: FVEG_03630 FVEG_07643
FOX: FOXG_04573 FOXG_05758
NHE: NECHADRAFT_44040
MAJ: MAA_10075
SSL: SS1G_01703
BFU: BCIN_02g03480
MBE: MBM_02254
ANG: ANI_1_1088094(An11g08610)
PTE: PTT_13757
 » show all
Taxonomy
Reference
1  [PMID:8776851]
  Authors
Kusumoto K, Hsieh DP
  Title
Purification and characterization of the esterases involved in aflatoxin biosynthesis in Aspergillus parasiticus.
  Journal
Can J Microbiol 42:804-10 (1996)
Reference
2  [PMID:15184162]
  Authors
Chang PK, Yabe K, Yu J
  Title
The Aspergillus parasiticus estA-encoded esterase converts versiconal hemiacetal  acetate to versiconal and versiconol acetate to versiconol in aflatoxin biosynthesis.
  Journal
Appl Environ Microbiol 70:3593-9 (2004)
DOI:10.1128/AEM.70.6.3593-3599.2004
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 3.1.1.94
IUBMB Enzyme Nomenclature: 3.1.1.94
ExPASy - ENZYME nomenclature database: 3.1.1.94
BRENDA, the Enzyme Database: 3.1.1.94

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