KEGG   ENZYME: 3.1.1.96Help
Entry
EC 3.1.1.96                 Enzyme                                 

Name
D-aminoacyl-tRNA deacylase;
Dtd2;
D-Tyr-tRNA(Tyr) deacylase;
D-Tyr-tRNATyr deacylase;
D-tyrosyl-tRNATyr aminoacylhydrolase;
dtdA (gene name)
Class
Hydrolases;
Acting on ester bonds;
Carboxylic-ester hydrolases
BRITE hierarchy
Sysname
D-aminoacyl-tRNA aminoacylhydrolase
Reaction(IUBMB)
a D-aminoacyl-tRNA + H2O = a D-amino acid + tRNA
Substrate
D-aminoacyl-tRNA;
H2O [CPD:C00001]
Product
D-amino acid [CPD:C00405];
tRNA [CPD:C00066]
Comment
The enzyme from Escherichia coli can cleave D-tyrosyl-tRNATyr, D-aspartyl-tRNAAsp and D-tryptophanyl-tRNATrp [1]. Whereas the enzyme from the archaeon Pyrococcus abyssi is a zinc protein, the enzyme from Escherichia coli does not carry any zinc [2].
History
EC 3.1.1.96 created 2014
Orthology
K09716  D-aminoacyl-tRNA deacylase
Genes
ATH: AT2G03800(GEK1)
ALY: ARALYDRAFT_322675 ARALYDRAFT_673756
CRB: 17885303
CSAT: 104710293 104779701 104790138
EUS: EUTSA_v10004640mg
BRP: 103875384
BNA: 106349382 106357766 106389301 106401553 111213388
BOE: 106301423 106324760
THJ: 104805212
CPAP: 110823080 110824276
CIT: 102624797
TCC: 18610176
GMX: 100808796
VRA: 106767281
VAR: 108324367
CCAJ: 109795748
CAM: 101489474
ADU: 107477251
AIP: 107629760
LJA: Lj0g3v0050309.1(Lj0g3v0050309.1) Lj0g3v0203889.1(Lj0g3v0203889.1) Lj0g3v0203889.2(Lj0g3v0203889.2) Lj4g3v1108050.1(Lj4g3v1108050.1) Lj4g3v1108080.1(Lj4g3v1108080.1)
FVE: 101299573
PPER: 18793887
PMUM: 103342018
PAVI: 110765583
ZJU: 107404713
CSV: 101218229
CMO: 103488450
MCHA: 111005213
CMAX: 111496050
CPEP: 111799184
RCU: 8264581
JCU: 105650605
POP: 7475625
JRE: 109014399
VVI: 100245778
CANN: 107855405
BVG: 104896133
SOE: 110806177
DOSA: Os08t0339200-01(Os08g0339200) Os09t0248000-01(Os09g0248000)
BDI: 100844903
ATS: 109745272(LOC109745272) 109762799(LOC109762799)
SBI: 8082261
ZMA: 100193788(AY104775)
SITA: 101767884
MUS: 103993711
DCT: 110100651
AOF: 109841892
ATR: 18433919
MJA: MJ_0166
MMP: MMP0990
MMD: GYY_05775
MAE: Maeo_0733
MVO: Mvol_0838
MAC: MA_2046
MBAR: MSBR2_0154
MBAK: MSBR3_1059
MMA: MM_3190
MMAC: MSMAC_2842
METM: MSMTP_1847
MTHE: MSTHC_0037
MTHR: MSTHT_0683
MHOR: MSHOH_1791
MBU: Mbur_1941
MMET: MCMEM_0165
MMH: Mmah_0177
MPY: Mpsy_1494
MTP: Mthe_0095
MCJ: MCON_0150
MHI: Mhar_1253
MHU: Mhun_0661
MLA: Mlab_1586
MPI: Mpet_2132
MBN: Mboo_2266
MPL: Mpal_0158
MKA: MK0939
AFU: AF_0625
FPL: Ferp_0278
GAC: GACE_0122
GAH: GAH_00260
HAL: VNG_0378C
HSL: OE_1560R(dtdA)
HHB: Hhub_1622(dtdA)
HALH: HTSR_1395
HHSR: HSR6_1467
HMA: rrnAC0704
HHI: HAH_1353
NPH: NP_0808A(dtdA)
NMO: Nmlp_1136(dtdA)
HUT: Huta_2476
HTI: HTIA_2252
HMU: Hmuk_2934
HWA: HQ_1244A(dtdA)
HWC: Hqrw_1272(dtdA)
HVO: HVO_0716(dtdA)
HME: HFX_0675
HLA: Hlac_0902
HTU: Htur_1372
NMG: Nmag_2781(dtdA)
NAT: NJ7G_4078
SALI: L593_04250
TAC: Ta0022
TVO: TVG0076358(TVG0076358)
PTO: PTO0612
FAI: FAD_1715
CDIV: CPM_0013
MEAR: Mpt1_c09240(dtdA)
MARC: AR505_0250
PHO: PH0006(PH0006)
PAB: PAB2349
PFU: PF1982
PFI: PFC_08670
PYN: PNA2_0807
PYS: Py04_0065
TKO: TK1422
TON: TON_0175
TGA: TGAM_0482
TSI: TSIB_0378
THE: GQS_03725
THA: TAM4_723
THM: CL1_0396
TLT: OCC_02169
THS: TES1_0279
TNU: BD01_0049
TEU: TEU_05730
PPAC: PAP_02225
ABI: Aboo_0227
ACJ: ACAM_0933
SMR: Smar_0445
IHO: Igni_1152
IIS: EYM_01385
DKA: DKAM_0853
TAG: Tagg_0722
IAG: Igag_1544
HBU: Hbut_0781
SSO: SSO2234
SOL: Ssol_0054
SSOA: SULA_0051
SSOL: SULB_0052
SSOF: SULC_0051
STO: STK_21210(dtdA)
SAI: Saci_0042
SID: M164_0052
SII: LD85_0052
SIH: SiH_0052
SIR: SiRe_0051
SIC: SiL_0051
MSE: Msed_0774
MCN: Mcup_1228
AHO: Ahos_2306
PAI: PAE2331
PIS: Pisl_0640
PCL: Pcal_1672
PAS: Pars_1544
PYR: P186_0583
POG: Pogu_0670
TNE: Tneu_1476
CMA: Cmaq_0773
TUZ: TUZN_0423
TTN: TTX_0836
VDI: Vdis_1960
VMO: VMUT_0373
ASC: ASAC_1030
NMR: Nmar_0387
NID: NPIRD3C_1980(dtdA)
NIN: NADRNF5_1791(dtdA)
NCT: NMSP_1337(dtdA)
NEV: NTE_01385
NCV: NCAV_1549
NBV: T478_1128
NDV: NDEV_0335(dtdA)
KCR: Kcr_0050
BARC: AOA65_2181(dtdA)
BARB: AOA66_0697(dtdA)
LOKI: Lokiarch_53870(dtdA)
 » show all
Taxonomy
Reference
1  [PMID:10918062]
  Authors
Soutourina J, Plateau P, Blanquet S
  Title
Metabolism of D-aminoacyl-tRNAs in Escherichia coli and Saccharomyces cerevisiae  cells.
  Journal
J Biol Chem 275:32535-42 (2000)
DOI:10.1074/jbc.M005166200
  Sequence
[eco:b3887] [sce:YDL219W]
Reference
2  [PMID:11568181]
  Authors
Ferri-Fioni ML, Schmitt E, Soutourina J, Plateau P, Mechulam Y, Blanquet S
  Title
Structure of crystalline D-Tyr-tRNA(Tyr) deacylase. A representative of a new class of tRNA-dependent hydrolases.
  Journal
J Biol Chem 276:47285-90 (2001)
DOI:10.1074/jbc.M106550200
  Sequence
[eco:b3887]
Reference
3  [PMID:16844682]
  Authors
Ferri-Fioni ML, Fromant M, Bouin AP, Aubard C, Lazennec C, Plateau P, Blanquet S
  Title
Identification in archaea of a novel D-Tyr-tRNATyr deacylase.
  Journal
J Biol Chem 281:27575-85 (2006)
DOI:10.1074/jbc.M605860200
  Sequence
[sso:SSO2234] [pab:PAB2349] [afu:AF_0625]
Reference
4  [PMID:17251192]
  Authors
Wydau S, Ferri-Fioni ML, Blanquet S, Plateau P
  Title
GEK1, a gene product of Arabidopsis thaliana involved in ethanol tolerance, is a  D-aminoacyl-tRNA deacylase.
  Journal
Nucleic Acids Res 35:930-8 (2007)
DOI:10.1093/nar/gkl1145
  Sequence
[ath:AT2G03800]
Other DBs
ExplorEnz - The Enzyme Database: 3.1.1.96
IUBMB Enzyme Nomenclature: 3.1.1.96
ExPASy - ENZYME nomenclature database: 3.1.1.96
BRENDA, the Enzyme Database: 3.1.1.96

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