Entry |
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Name |
acyl-CoA hydrolase;
acyl coenzyme A thioesterase;
acyl-CoA thioesterase;
acyl coenzyme A hydrolase;
thioesterase B;
thioesterase II;
acyl-CoA thioesterase
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Class |
Hydrolases;
Acting on ester bonds;
Thioester hydrolases
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Sysname |
acyl-CoA hydrolase
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Reaction(IUBMB) |
acyl-CoA + H2O = CoA + a carboxylate [RN: R00383]
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Reaction(KEGG) |
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Substrate |
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Product |
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Comment |
Broad specificity for medium- to long-chain acyl-CoA. Insensitive to NAD+ (cf. EC 3.1.2.19 ADP-dependent medium-chain-acyl-CoA hydrolase)
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History |
EC 3.1.2.20 created 1992
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Orthology |
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Genes |
GAJ: | MY490_08015 MY490_13980 |
ACIT: | HPK19_01810 HPK19_08940 |
» show all
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Reference |
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Authors |
Alexson SE, Svensson LT, Nedergaard J. |
Title |
NADH-sensitive propionyl-CoA hydrolase in brown-adipose-tissue mitochondria of the rat. |
Journal |
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Other DBs |
ExplorEnz - The Enzyme Database: | 3.1.2.20 |
ExPASy - ENZYME nomenclature database: | 3.1.2.20 |
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