KEGG   ENZYME: 3.1.2.20
Entry
EC 3.1.2.20                 Enzyme                                 
Name
acyl-CoA hydrolase;
acyl coenzyme A thioesterase;
acyl-CoA thioesterase;
acyl coenzyme A hydrolase;
thioesterase B;
thioesterase II;
acyl-CoA thioesterase
Class
Hydrolases;
Acting on ester bonds;
Thioester hydrolases
Sysname
acyl-CoA hydrolase
Reaction(IUBMB)
acyl-CoA + H2O = CoA + a carboxylate [RN:R00383]
Reaction(KEGG)
R00383
Substrate
acyl-CoA [CPD:C00040];
H2O [CPD:C00001]
Product
CoA [CPD:C00010];
carboxylate [CPD:C00060]
Comment
Broad specificity for medium- to long-chain acyl-CoA. Insensitive to NAD+ (cf. EC 3.1.2.19 ADP-dependent medium-chain-acyl-CoA hydrolase)
History
EC 3.1.2.20 created 1992
Orthology
K01073  acyl-CoA hydrolase
Genes
AFUSEYZ66_02545
BMABMA0492
BMVBMASAVP1_A2516
BMLBMA10229_A0890
BMNBMA10247_0258
BPSBPSL2470
BPMBURPS1710b_2941
BPLBURPS1106A_2888
BPDBURPS668_2827
BPRGBP346_A3008
BSAVWS86_06005
BGLbglu_1g09210
BPHBphy_0794
BANBA_2053
BARGBAA_2053
BATBAS1906
BAHBAMEG_2537
BAIBAA_2120
BAXH9401_1948
BANTA16_20890
BANRA16R_21160
BANSBAPAT_1962
BANHHYU01_10275
BANVDJ46_857
BCEBC2038
BCABCE_2122
BCZBCE33L1859
BCRBCAH187_A2154
BCBBCB4264_A2043
BCUBCAH820_2086
BCGBCG9842_B3266
BCQBCQ_2038
BCXBCA_2125
BALBACI_c20150
BNCBCN_1968
BCFbcf_10065
BCERBCK_24375
BCEFBcrFT9_01662
BCYBcer98_1542
BTKBT9727_1869
BTLBALH_1815
BTBBMB171_C1822
BTTHD73_2216
BTHRYBT1520_11045
BTHIBTK_11190
BTCCT43_CH1994
BTFYBT020_10650
BTMMC28_1263
BTGBTB_c21080
BTIBTG_09750
BTNBTF1_07585
BTHTH175_ch2021
BTHUYBT1518_11330
BTWBF38_3265
BTHYAQ980_19915
BWEBcerKBAB4_1903
BWWbwei_2973(ykhA)
BMYOBG05_3939
BTYBtoyo_4609
BMYCDJ92_4605
BBYCY96_09280
BWDCT694_11120
BTROFJR70_09380
BMOBMLA2C4_10390
BNTGSN03_09975
BPACLMD38_16350
GAJMY490_08015 MY490_13980
ACITHPK19_01810 HPK19_08940
TTHTT_C1452
DINSelin_1205
 » show all
Reference
1  [PMID:2570608]
  Authors
Alexson SE, Svensson LT, Nedergaard J.
  Title
NADH-sensitive propionyl-CoA hydrolase in brown-adipose-tissue mitochondria of the rat.
  Journal
Biochim Biophys Acta 1005:13-9 (1989)
DOI:10.1016/0005-2760(89)90025-8
Other DBs
ExplorEnz - The Enzyme Database: 3.1.2.20
IUBMB Enzyme Nomenclature: 3.1.2.20
ExPASy - ENZYME nomenclature database: 3.1.2.20
BRENDA, the Enzyme Database: 3.1.2.20
CAS: 37270-64-7

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