KEGG   ENZYME: 3.1.2.21
Entry
EC 3.1.2.21                 Enzyme                                 

Name
dodecanoyl-[acyl-carrier-protein] hydrolase;
lauryl-acyl-carrier-protein hydrolase;
dodecanoyl-acyl-carrier-protein hydrolase;
dodecyl-acyl-carrier protein hydrolase;
dodecanoyl-[acyl-carrier protein] hydrolase;
dodecanoyl-[acyl-carrier-protein] hydrolase
Class
Hydrolases;
Acting on ester bonds;
Thioester hydrolases
Sysname
dodecanoyl-[acyl-carrier protein] hydrolase
Reaction(IUBMB)
a dodecanoyl-[acyl-carrier protein] + H2O = an [acyl-carrier protein] + dodecanoate [RN:R04014]
Reaction(KEGG)
R04014;
(other) R08157 R08158 R12329
Substrate
dodecanoyl-[acyl-carrier protein] [CPD:C05223];
H2O [CPD:C00001]
Product
[acyl-carrier protein] [CPD:C00229];
dodecanoate [CPD:C02679]
Comment
Acts on the acyl-carrier-protein thioester of C12 and, with a much lower activity, C14 fatty acids. The derivative of oleic acid is hydrolysed very slowly (cf. EC 3.1.2.14, oleoyl-[acyl-carrier-protein] hydrolase).
History
EC 3.1.2.21 created 1999
Pathway
ec00061  Fatty acid biosynthesis
ec01100  Metabolic pathways
Orthology
K01071  medium-chain acyl-[acyl-carrier-protein] hydrolase
K10781  fatty acyl-ACP thioesterase B
Genes
HSA: 55301(OLAH)
PTR: 450320(OLAH)
PPS: 100969629(OLAH)
PON: 100441345(OLAH)
NLE: 100601676(OLAH)
MCC: 697753
MCF: 102142933(OLAH)
CSAB: 103237931(OLAH)
RRO: 104664475(OLAH)
RBB: 108530852(OLAH)
CJC: 100402846(OLAH)
SBQ: 101043966(OLAH)
MMU: 99035(Olah)
MCAL: 110290252(Olah)
MPAH: 110334162(Olah)
RNO: 64669(Olah)
CGE: 100755723(Olah)
NGI: 103735189(Olah)
HGL: 101699165(Olah)
OCU: 100349940
TUP: 102488474(OLAH)
BTA: 617347(OLAH)
BOM: 102273387(OLAH)
BIU: 109567605(OLAH)
BBUB: 102413725(OLAH)
CHX: 102180055(OLAH)
OAS: 101116669(OLAH)
SSC: 100627446(OLAH)
CFR: 102522778(OLAH)
BACU: 103001653(OLAH)
PCAD: 102991368(OLAH)
ECB: 100068833(OLAH)
EPZ: 103556832(OLAH)
EAI: 106840468(OLAH)
MYB: 102239550(OLAH)
MYD: 102759672(OLAH)
MNA: 107534813(OLAH)
HAI: 109393805(OLAH)
DRO: 112320938(OLAH)
RAY: 107504822(OLAH)
LAV: 100675942(OLAH)
TMU: 101361105
MDO: 100027206(OLAH)
SHR: 100914322(OLAH)
PCW: 110209026(OLAH)
OAA: 100077700(OLAH)
GGA: 420532(OLAH)
MGP: 100547884(OLAH)
CJO: 107309023(OLAH)
NMEL: 110393652(OLAH)
APLA: 101793583(OLAH)
ACYG: 106039692(OLAH)
TGU: 100224799(OLAH)
LSR: 110482463(OLAH)
SCAN: 103813106(OLAH)
GFR: 102031766(OLAH)
FAB: 101815966(OLAH)
PHI: 102106226(OLAH)
PMAJ: 107198685(OLAH)
CCAE: 111924181(OLAH)
CCW: 104689201(OLAH)
ETL: 114065102(OLAH)
FPG: 101922325(OLAH)
FCH: 102058635(OLAH)
CLV: 102084717(OLAH)
EGZ: 104128444(OLAH)
NNI: 104022905(OLAH)
ACUN: 113477405(OLAH)
PADL: 103922402(OLAH)
AAM: 106483605(OLAH)
ASN: 102386110(OLAH)
AMJ: 102557880(OLAH)
PSS: 102454966(OLAH)
CMY: 102930778(OLAH)
CPIC: 101937274(OLAH)
XLA: 108718823(olah.L)
XTR: 407865(olah)
NPR: 108795592(OLAH)
DRE: 568096(olah)
CCAR: 109111875
IPU: 100528864(olah)
PHYP: 113534943(olah)
AMEX: 103035172(olah)
EEE: 113578374(olah)
TRU: 101061874(olah)
LCO: 104928057(olah)
MZE: 101474377(olah)
ONL: 100691905(olah)
OLA: 101160493(olah)
XMA: 102216960(olah)
XCO: 114155297(olah)
PRET: 103473026(olah)
CVG: 107098937(olah)
NFU: 107394887(olah)
KMR: 108228836(olah)
ALIM: 106530105(olah)
AOCE: 111586624(olah)
CSEM: 103393954(olah)
POV: 109643703(olah)
LCF: 108899375(olah)
SDU: 111230514(olah)
SLAL: 111661082(olah)
HCQ: 109513606(olah)
BPEC: 110168928(olah)
MALB: 109958738(olah)
SASA: 100196232(olah)
OTW: 112264938(olah)
SALP: 111956208(olah)
ELS: 105009858(olah)
SFM: 108933393(olah)
PKI: 111834098(olah)
LCM: 102354603(OLAH)
CMK: 103181559(olah)
RTP: 109926026(olah)
SPU: 582714
PCAN: 112565315
CRG: 105339010
MYI: 110445787
NVE: 5513765
EPA: 110234691
PDAM: 113679240
SPIS: 111321809
ATH: AT1G08510(FATB)
ALY: 9325763
CRB: 17897852
CPAP: 110823017
CIT: 102577983(FATB) 102623135
LJA: Lj0g3v0119999.1(Lj0g3v0119999.1) Lj1g3v1498440.1(Lj1g3v1498440.1)
JCU: 105634942(FAT-L2) 105634943(FAT-L3) 105639285
NNU: 104592290
DOSA: Os02t0644700-01(Os02g0644700) Os06t0143400-01(Os06g0143400) Os06t0596300-01(Os06g0596300) Os11t0659500-01(Os11g0659500)
ATS: 109747972(LOC109747972) 109761208(LOC109761208)
ZMA: 100281497 100283590(cl525_1a) 100284647(si496011d04) 100284999 103638097
APRO: F751_4546
SMIN: v1.2.038836.t1(symbB.v1.2.038836.t1)
VTA: B0225
PSEM: TO66_00670
CJA: CJA_3196
HCH: HCH_07001
BPM: BURPS1710b_A0895(barC)
BPSE: BDL_5212(lgrE)
BPSM: BBQ_4320(lgrE)
BPSU: BBN_5275(lgrE)
BPSD: BBX_4378(lgrE)
BPK: BBK_4542(lgrE)
BPSH: DR55_5927(lgrE)
BPSA: BBU_4202(lgrE)
BPSO: X996_5724(lgrE)
BUT: X994_5287(lgrE)
BTQ: BTQ_3859(lgrE)
BTJ: BTJ_4891(lgrE)
BTZ: BTL_5685(lgrE)
BTD: BTI_5181(lgrE)
BTV: BTHA_4525(lgrE)
BTHE: BTN_5347(lgrE)
BTHM: BTRA_5621(lgrE)
BTHA: DR62_5485
BTHL: BG87_5692(lgrE)
BOK: DM82_6084(lgrE)
BOC: BG90_4581(lgrE)
BGU: KS03_2775
BUL: BW21_4717(lgrE)
AMAR: AMRN_2099
ACAA: ACAN_2137
AMOL: AMOL_2063
ARC: ABLL_1418
DEU: DBW_2549
DDE: Dde_1605
DBA: Dbac_2031
DOL: Dole_2590
DAL: Dalk_2643
DALK: DSCA_36210
ADE: Adeh_4078
CCX: COCOR_05110(lgrE1)
SCL: sce0356
RPC: RPC_1862
XAU: Xaut_1005
MET: M446_0169
BBAT: Bdt_2438
BBAC: EP01_08650
BYA: BANAU_3418(bacT)
BAMA: RBAU_3373
BAMB: BAPNAU_3426(nrsG)
BAMT: AJ82_15575
BMP: NG74_03403(lgrE)
BQY: MUS_3854(lgrE)
BAMC: U471_28670
BAMF: U722_01270
BWW: bwei_3108
BACP: SB24_12550
BACB: OY17_19480
BEO: BEH_10690
PSYO: PB01_17140
BBE: BBR47_28880(lgrE)
PPY: PPE_02177
PPM: PPSC2_11385(pteH)
PPO: PPM_2180(pteH)
PPOL: X809_11765
PPQ: PPSQR21_022610(grsT)
PPOY: RE92_00970
PSAB: PSAB_02995
LLK: LLKF_1167(ylfFG)
LLT: CVCAS_1113(ylfFG)
LLS: lilo_1043
LLM: llmg_1415
LLC: LACR_1253
LLR: llh_6315
LLW: kw2_1088
LLJ: LG36_1240(ylfFG)
LGR: LCGT_0882
LGV: LCGL_0903
SPY: SPy_1042
SPYA: A20_0807(ylfFG)
SPS: SPs1179
SPF: SpyM50993
STG: MGAS15252_0793(fatA)
STX: MGAS1882_0789(fatA)
SPYH: L897_03990
SPN: SP_1408
SPD: SPD_1239
SPR: spr1265
SPW: SPCG_1396
SJJ: SPJ_1307
SPX: SPG_1349
SNT: SPT_0866
SND: MYY_0882
SPNN: T308_03990
SPV: SPH_1539
SPP: SPP_1427
SNP: SPAP_1439
SAG: SAG0891
SAN: gbs0908
SAK: SAK_1014
SGC: A964_0896
SAGM: BSA_9790
SAGI: MSA_10390
SAGR: SAIL_10350
SAGP: V193_04240
SAGC: DN94_04240
SAGE: EN72_05190
SAGG: EN73_04895
SAGN: W903_0982
SMU: SMU_1417c
SMUA: SMUFR_1230
STC: str1235
STL: stu1235
STE: STER_1215
STN: STND_1187
STW: Y1U_C1152
STHE: T303_07115
SSA: SSA_1076
SSI: SSU1263
SUP: YYK_06055
SSUY: YB51_6435
SSUT: TL13_1251
SSUI: T15_1458
SGO: SGO_1328
SEZ: Sez_1208
SEQ: SZO_07520
SEQU: Q426_03070
SEU: SEQ_1394
SUB: SUB1087
SDS: SDEG_1235
SDA: GGS_1119
SDC: SDSE_1211
SGT: SGGB_1446
SMB: smi_0721
SOR: SOR_0721
STK: STP_0942
STB: SGPB_1351
SCF: Spaf_1242
STJ: SALIVA_0834(fat)
SMN: SMA_1450
SIF: Sinf_1259
SIB: SIR_0879
SIU: SII_0896
SANG: SAIN_0781
SANC: SANR_0885
SANS: DK43_06180
SCG: SCI_1032
SCON: SCRE_0973
SCOS: SCR2_0973
SIK: K710_0795
SLU: KE3_1341
STRN: SNAG_0682
LPL: lp_0708
LPJ: JDM1_0584(fat)
LPS: LPST_C0539(fat)
LPZ: Lp16_0558
LJO: LJ_0432
LJH: LJP_0412
LAC: LBA0386
LAD: LA14_0382
LAF: SD55_0383
LSA: LCA_0345
LSL: LSL_1220
LSI: HN6_01008
LSJ: LSJ_1200c
LDB: Ldb1626
LBU: LBUL_1506
LDL: LBU_1387
LBR: LVIS_0609
LCA: LSEI_2254
LCS: LCBD_2433
LCE: LC2W_2415
LPAP: LBPC_2185
LCB: LCABL_24360(fat)
LGA: LGAS_0377
LRE: Lreu_0335
LRF: LAR_0324
LRT: LRI_1603
LHE: lhv_0409
LHL: LBHH_0363
LHV: lhe_1698
LHH: LBH_0330
LHD: HUO_02930
LFE: LAF_0292
LFR: LC40_0208
LFF: LBFF_0311
LRH: LGG_02257(fat)
LRG: LRHM_2169
LRL: LC705_02244(fat)
LRA: LRHK_2253
LAM: LA2_02005
LBH: Lbuc_1367
LKE: WANG_0083
LRM: LRC_05930
LSN: LSA_04860
LAE: LBAT_0447
LPW: LpgJCM5343_03770(fatA)
PPE: PEPE_1476
PPEN: T256_07290
PCE: PECL_504(fat)
EFA: EF0365
EFL: EF62_0698
EFS: EFS1_0250
EFQ: DR75_2357
EFU: HMPREF0351_12195(fat)
EFM: M7W_2204
EHR: EHR_07655
ECAS: ECBG_00012
EMU: EMQU_0686(fat)
EDU: LIU_11930
ESG: EsVE80_05970(fat)
MPS: MPTP_1782
MPX: MPD5_0284
THL: TEH_09530
OOE: OEOE_1403
LME: LEUM_0283
LMM: MI1_01165
LMK: LMES_0227
LCI: LCK_01510(fat)
LKI: LKI_06955
WKO: WKK_04350
WCE: WS08_1104
WCT: WS74_1172
CML: BN424_499(fat)
CARC: NY10_1348
CAE: SMB_G3632
CAY: CEA_G3598
CPR: CPR_2637
CTC: CTC_00119
CBA: CLB_3707
CBH: CLC_3613
CBY: CLM_4119
CBL: CLK_3098
CBK: CLL_A3574
CBB: CLD_0860
CBI: CLJ_B3953
CBN: CbC4_0039
CBT: CLH_3368
CBF: CLI_3859
CBM: CBF_3808
CBEI: LF65_05752
CPAS: Clopa_4832
CSQ: CSCA_4158
CTYK: CTK_C30150
AOE: Clos_0894
CTH: Cthe_3072
CSD: Clst_0940
ESR: ES1_26570
ESU: EUS_25740
CCEL: CCDG5_2079
RCH: RUM_05690
RUM: CK1_30460
FPR: FP2_08050
FPA: FPR_28760
BPB: bpr_I2609
BFI: CIY_02570
BHU: bhn_I2472
RIX: RO1_16200
RIM: ROI_30310
COO: CCU_05150
CCT: CC1_16030
ROB: CK5_35000
CPY: Cphy_0251
CSO: CLS_14890
BPRL: CL2_10690
EHL: EHLA_0683
RTO: RTO_14210
ERT: EUR_03270
ERA: ERE_22810
SALQ: SYNTR_1492
DHD: Dhaf_3168
DAE: Dtox_2679
ELM: ELI_0646
OVA: OBV_13720
BPRS: CK3_19730
CHY: CHY_0816
FMA: FMG_1119
APR: Apre_0268
PFT: JBW_04659
MANA: MAMMFC1_02823(lgrE)
STED: SPTER_12040(lgrE)
ACL: ACL_0794
STRE: GZL_02938
SLE: sle_09380(sle_09380)
AMYY: YIM_17690(lgrE2)
SNA: Snas_3604
APV: Apar_0635
OLS: Olsu_0808
HHG: XM38_019620(lgrE)
AMR: AM1_A0220
CYT: cce_1421
CTHE: Chro_3667
OTE: Oter_0985
AMU: Amuc_1725
RUL: UC8_43450(lgrE)
TPED: TPE_1742
BRM: Bmur_2369
BPW: WESB_1170
BIP: Bint_2070
EPO: Epro_1221
TLI: Tlie_1783
SBR: SY1_19710
FSC: FSU_2108
BVU: BVU_2557
BXY: BXY_12270
PDI: BDI_2070
TFO: BFO_0454
PSAC: PSM36_1268
PRU: PRU_1075
AFD: Alfi_2758
ASH: AL1_28690
BACC: BRDCF_p758
MBAS: ALGA_3233
SRU: SRU_0057
SRM: SRM_00055
SLI: Slin_6353
FAE: FAES_1603(fat)
FLM: MY04_0712
FJO: Fjoh_3454
FIN: KQS_05575(3.1.2.14)
COC: Coch_0202
MPW: MPR_2035
CHZ: CHSO_1940
CPRV: CYPRO_2938
NDE: NIDE2157
NJA: NSJP_3903(lgrE)
 » show all
Reference
1  [PMID:1989513]
  Authors
Pollard MR, Anderson L, Fan C, Hawkins DJ, Davies HM.
  Title
A specific acyl-ACP thioesterase implicated in medium-chain fatty acid production in immature cotyledons of Umbellularia californica.
  Journal
Arch Biochem Biophys 284:306-12 (1991)
DOI:10.1016/0003-9861(91)90300-8
Reference
2  [PMID:1898097]
  Authors
Davies HM, Anderson L, Fan C, Hawkins DJ.
  Title
Developmental induction, purification, and further characterization of 12:0-ACP thioesterase from immature cotyledons of Umbellularia californica.
  Journal
Arch Biochem Biophys 290:37-45 (1991)
DOI:10.1016/0003-9861(91)90588-A
Other DBs
ExplorEnz - The Enzyme Database: 3.1.2.21
IUBMB Enzyme Nomenclature: 3.1.2.21
ExPASy - ENZYME nomenclature database: 3.1.2.21
BRENDA, the Enzyme Database: 3.1.2.21
CAS: 137903-37-8

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