KEGG   ENZYME: 3.1.2.23
Entry
EC 3.1.2.23                 Enzyme                                 
Name
4-hydroxybenzoyl-CoA thioesterase
Class
Hydrolases;
Acting on ester bonds;
Thioester hydrolases
Sysname
4-hydroxybenzoyl-CoA hydrolase
Reaction(IUBMB)
4-hydroxybenzoyl-CoA + H2O = 4-hydroxybenzoate + CoA [RN:R01301]
Reaction(KEGG)
R01301
Substrate
4-hydroxybenzoyl-CoA [CPD:C02949];
H2O [CPD:C00001]
Product
4-hydroxybenzoate [CPD:C00156];
CoA [CPD:C00010]
Comment
This enzyme is part of the bacterial 2,4-dichlorobenzoate degradation pathway.
History
EC 3.1.2.23 created 1999
Pathway
ec00130  Ubiquinone and other terpenoid-quinone biosynthesis
ec00362  Benzoate degradation
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
ec01120  Microbial metabolism in diverse environments
Orthology
K01075  4-hydroxybenzoyl-CoA thioesterase
Genes
KLWDA718_25975
EBTEBL_c27880
XDOXDD1_0581
XHOA9255_13145
XBUHGO23_11085
PRGRB151_004970
PALACO695_02400
PHEINCTC12003_00493
PRQCYG50_13610
PRJNCTC6933_00561
LABLA76x_0569
LAQGLA29479_2644
LMBC9I47_0598
PAEPA0968
PAEVN297_1002(ybgC)
PAEIN296_1002(ybgC)
PAUPA14_51770(ybgC)
PAPPSPA7_4540(ybgC)
PAGPLES_43461
PAFPAM18_4069
PNCNCGM2_1775(ybgC)
PAEBNCGM1900_1747(ybgC)
PDKPADK2_20850
PSGG655_20505
PRPM062_04760
PAEPPA1S_21570
PAERPA1R_gp4495
PAEMU769_20940
PAELT223_22205
PAESSCV20265_4552
PAEUBN889_01022
PAEGAI22_12370
PAECM802_998(ybgC)
PAEOM801_1002(ybgC)
PMYPmen_1273
PMKMDS_1307
PREPCA10_44240
PPSEBN5_3084
PFUWKF707C_43800
PALCA0T30_16225
PCQPcP3B5_17220(ybgC_1)
PMUIG4G71_10285(ybgC)
PPUPP_1218
PPFPput_1247
PPGPputGB1_4200
PPWPputW619_3997
PPTPPS_3999
PPBPPUBIRD1_1255
PPIYSA_07517
PPXT1E_5727
PPUHB479_20300
PPUTL483_25335
PPUNPP4_11570(ybgC)
PPUDDW66_4438
PFVPsefu_1530
PMONX969_19555
PMOTX970_19190
PMOSO165_001105 O165_011230
PPJRK21_00480
PORAPT59_14510
PMOLCLJ08_19160(ybgC)
PSTPSPTO_3976
PSBPsyr_1411
PSYRN018_18605
PSPPSPPH_3771
PSAVPSA3335_07100
PAMGBKM19_010095(ybgC)
PCIPCH70_13190
PAVLBKM03_08970(ybgC)
PVDCFBP1590__3976
PCABJGS08_07995(ybgC)
PCOFPOR16_17160(ybgC)
PFLPFL_4762(ybgC)
PPRCPFLCHA0_c47420(ybgC)
PPROPPC_4770(ybgC)
PFEPSF113_4614
PFNHZ99_07205 HZ99_10605
PFOPfl01_4406
PFSPFLU_4912
PFCPflA506_4221(ybgC)
PPZH045_15440
PFBVO64_1765
PMANOU5_4878
PTVAA957_20290
PCGAXG94_09170
PVRPverR02_24895
PAZOAYR47_00485
POIBOP93_20580
PRXHRH33_21445(ybgC)
PFWPF1751_v1c44060(ybgC)
PFFPFLUOLIPICF714110
PFXA7318_22695
PENPSEEN4091
PSAPST_2807
PSZPSTAB_2829
PSRPSTAA_2930
PSCA458_14700
PSJPSJM300_07325
PSHPsest_1498
PSTUUIB01_06925
PSTTCH92_07145
PCHLLLJ08_06650(ybgC)
PBMCL52_13830
PLULFOB45_11050(ybgC)
PBAPSEBR_a4439
PBCCD58_23505
PPUUPputUW4_04295
PDRH681_17800
PSVPVLB_19145
PSKU771_25465
PKCPKB_1388
PCHEY04_24260
PCZPCL1606_15020
PCPJM49_07435
PFZAV641_16620
PLQAA042_17045
PALKPSAKL28_40370
PRHLT40_05005
PSWLK03_11285
PPVNJ69_12425
PSESPSCI_3265
PSEMTO66_24360
PSECCCOS191_4073
PPSYAOC04_13910
PSOSPOS17_4737(ybgC)
PKRAYO71_23985
PFKPFAS1_04955
PANRA7J50_4682
PPSLBJP27_06160
PSETTHL1_4467
PSILPMA3_23235
PYMAK972_1112
PSEDDM292_04695(ybgC) DM292_17545
PKEDLD99_22255(ybgC)
PALLUYA_06025
PUMHGP31_24925(ybgC)
POJPtoMrB4_42540
PGGFX982_02627
PPSHG5J76_20295(ybgC)
PGYAWU82_26030(ybgC)
PLALFXN65_21430(ybgC)
PSEJHNQ25_18160(ybgC)
PVKEPZ47_23505(ybgC)
PEZHWQ56_21775(ybgC)
PBZGN234_24770(ybgC)
PKHJLK41_06640(ybgC) JLK41_15645
PTYJWV26_16940(ybgC)
PMAOPMYSY11_1512(ybgC)
PATAJWU58_06945(ybgC)
PDWBV82_0618(ybgC)
PZEHU754_023260(ybgC)
PMOEHV782_022510(ybgC)
PCAMHNE05_11865(ybgC)
PSEPC4K39_4865
PVWHU752_008290(ybgC)
PTRTHU722_0014825 HU722_0023435(ybgC)
PXAKSS93_23030(ybgC)
PSAMHU731_009785(ybgC)
PTZHU718_023845(ybgC)
PQIKH389_06760(ybgC)
PSHHHU773_021550(ybgC)
PXNHU772_018415(ybgC)
PHVHU739_022705(ybgC)
PPRGHU725_017160(ybgC)
PNNKEM63_11975(ybgC)
PANHHU763_018220(ybgC)
PASGKSS96_22810(ybgC)
PFAKKSS94_20485(ybgC)
PMUYKSS95_21280(ybgC)
PMAMKSS90_06465(ybgC)
PAZEKSS91_22995(ybgC)
PALVKSS97_07060(ybgC)
PPHABVH74_10005
PORYEJA05_21580(ybgC)
PWZJ7655_06050(ybgC)
PTKEXN22_07890(ybgC)
PTWTUM18999_45160
PZAHU749_023435(ybgC)
PIEHU724_021985(ybgC)
PWYHU734_006865(ybgC)
PTAENCTC10697_03206(ybgC)
PGFJ0G10_24265(ybgC)
PCAVD3880_07220(ybgC)
AVNAvin_14220 Avin_36680(ybgC)
AVLAvCA_14220 AvCA_36680(ybgC)
AVDAvCA6_14220 AvCA6_36680(ybgC)
ACXAchr_12920(ybgC)
PBBAKN87_06390
EMODM558_14475
HPEGEAO82_07560(ybgC)
HAESLO767_03995(ybgC)
MAQMaqu_1703
MHCMARHY1592(ybgC)
MSXAU14_00735
MLQASQ50_20260
MARAD0851_03430
HMIsoil367_07720(ybgC)
CEBB0D95_01235
CELLCBR65_21680
CEGD0C16_22585(ybgC)
TTUTERTU_3433(ybgC)
SPOIIMCC21906_02758
SNANI6N98_14635(ybgC)
ZALAZF00_05625
OSGBST96_13745
MTHDA3224_03380
MICCAUP74_00187(ybgC)
MAGAMag101_13885
MIIBTJ40_03680(ybgC) BTJ40_10620
MICTFIU95_03620(ybgC) FIU95_09570
MHYDGTQ55_04770(ybgC)
MCELLPW13_11030(ybgC)
MICZGL2_06410
HJABST95_18820
GAIIMCC3135_14660
HCHHCH_03404
CSACsal_1849
HELHELO_3952
HAKKO116_00194 KO116_00936
HAMHALO3248
HALOBWR19_09250
HOLHORIV_22120
HSRHSBAA_20220
HTTHZS52_20755
HCAMI4484_07600 I4484_11070(ybgC) I4484_15235
HSXHNO51_07010 HNO51_10775(ybgC) HNO51_15155
HSVHNO53_10060(ybgC) HNO53_15665
HTXEKK97_12055(ybgC) EKK97_17075
CMAIBFX80_09195
ABOABO_0754
ADIB5T_03230
APACS7S_06315
ALNAS19_07790
AXEP40_01500 P40_15100
KAKKalk_19945(ybgC)
MMWMmwyl1_3016
MPCMar181_1045
MPRIMP3633_1211
MARDIBG28_06895
MFOIJSY38_15860
MPRFJ8N69_12535
MARSA8C75_04825
MGEOCFI10_08470(ybgC)
MSECLN244_09210(ybgC)
BSANCHH28_03615
VCWGJQ55_08540(ybgC)
GSNYC6258_02578
EBHBSEPE_1076(ybgC)
GPBHDN1F_32790
CRZD1345_00255
CHAECH06BL_00490
RSORSc1827 RSp0038
RSLRPSI07_mp0054
RSNRSPO_m00054(ybgC)
RSMCMR15_11834 CMR15_mp10040
RSEF504_1562 F504_3544
RSYRSUY_32600
RPIRpic_3837
RPFRpic12D_3950
RPJN234_03105 N234_14065 N234_23135
RMNTK49_19430
RINACS15_5525
RPUCDC45_09395 CDC45_17775
RSGJK151_22800
REHH16_A2456(h16_A2456)
CNCCNE_1c23650 CNE_2c20780
CUHBJN34_13170 BJN34_23985 BJN34_29265
REUReut_A2179
RMERmet_2197
CTIRALTA_A1987 RALTA_B0114
CBWRR42_m2746 RR42_s0687
CGDCR3_1769
CCUPBKK81_14230
CUPBKK80_15165
CUUBKK79_17840
CPAUEHF44_11775
COXE0W60_21730
BURBcep18194_A4902
BCJBCAL1158
BGLbglu_2g11430
BGUKS03_4780
BUGBC1001_4667
BGFBC1003_4831
BYIBYI23_A013610 BYI23_D000280 BYI23_D002080
BUEBRPE67_ACDS14030 BRPE67_DCDS02310 BRPE67_DCDS03830
BUQAC233_26690
BGPBGL_2c14270
BPLAbpln_2g15030
BUMAXG89_31300
BXEBxe_B0277
BXBDR64_5618
BPHBphy_4073
BGEBC1002_4976
BPXBUPH_01242
BPYBphyt_7163
BUZAYM40_28285 AYM40_34350
BFNOI25_5788
BCAIK788_0001054
PSPWBJG93_22135
PARBCJU94_27900
PHSC2L64_12775 C2L64_18740
PTERC2L65_16575 C2L65_27695
PGPCUJ91_29545
PCJCUJ87_28540
PTSCUJ90_23195
PCAFDSC91_003273
PMEGFNZ07_03655
PTROG5S35_15700
PGISI6I06_27435
PACPFAZ97_19945
PACSFAZ98_15630
PDIOPDMSB3_3187.1
PPKU875_07415 U875_07760
PPNODA70_00060 DA70_00455
PPNMLV28_05860 LV28_06215
PRBX636_02165
PPULRO07_00205 RO07_24810
PSPUNA29_11430
PAPISG18_00500 SG18_14780 SG18_23380
PVEUC34_16565
POXMB84_21350
PTXABW99_11395 ABW99_15295
PFGAB870_03390
PNRAT302_15615 AT302_16705
PANDDRB87_15245
PFIBPI93_011470
PLGNCTC10937_01537(ybgC)
CABASBC2_47180
BUOBRPE64_DCDS01920
BPEBP0312
BPCBPTD_0307
BPERBN118_0335
BPETB1917_0314
BPEUQ425_35250
BPARBN117_4013
BPABPP3939
BBHBN112_4010
BBRBB4412
BBMBN115_4088
BBXBBS798_4189
BPTBpet0554
BAVBAV3019
BHOD560_1956
BHMD558_1941
BHZACR54_04138(fadM)
BTRMSAMEA390648700749
BPDZBBN53_02405
BGMCAL15_21095
BOJCBF45_09685
AXYAXYL_00589 AXYL_02928
AXONH44784_015901
AXNAX27061_0600
AXXERS451415_00592(fadM_1)
ADTAPT56_03085
AISBUW96_04725 BUW96_05675 BUW96_22900
ASWCVS48_03405
ACHRC2U31_07690
ACHBDVB37_02415
ADYHLG70_19145
PUDG9Q38_02475
AKATKWG_07360
CDNBN940_15386
AFAUZ73_10395
AFQAFA_00265
AAQUD3M96_00250
AAMMFE795_00225
PHNPAEH1_09410
PIGEGT29_06000 EGT29_09025 EGT29_22810
PACRFXN63_07920
KGYEHF36_09780
RFRRfer_0270
RSBRS694_10305
RHYRD110_17125
RHFEUB48_13075
RHGEXZ61_19465
POLBpro_0588 Bpro_3115 Bpro_4124
PNAPnap_0799 Pnap_3622
POSDT070_04460
POOF7R28_04990
AAAAcav_3343
VEIVeis_1590
DTSBI380_01290
DHKBO996_20210
DLAI6G47_02030
VAPVapar_0657 Vapar_1512 Vapar_3916
VPEVarpa_1667 Varpa_4528
VPDVAPA_1c16040 VAPA_1c40390
VBOCKY39_09095 CKY39_24995
VAMC4F17_10830 C4F17_30250
CTTCtCNB1_0395
CTESO987_02035
CODOLAD35_21575
RTARta_32470
RTEAHK414_04955
OTKC6570_11150
OTDJ1M35_11655
LIML103DPR2_01473
LIHL63ED372_00985
HYRBSY239_2242
HYBQ5W_08945
HYLLPB072_16190
HYCE5678_08875
HPSEHPF_07955
HYNF9K07_12100
HTNKI616_18265
DIHG7047_27135
DRGH9K76_22560
SIMPC6571_08295
CBAASRAA_0575
STHMIS481_10695
PBHAAW51_1944
KIAG8A07_17935
HSEHsero_4010
HSZACP92_20020
HRBHrubri_3964 Hrubri_4428
HEEhmeg3_01110
HHFE2K99_20880
HFRG5S34_21770
GLCJQN73_16700
SUTTSUTMEG_20550
SUTKFG381_06555
SWSI6J16_11940
LCHLcho_0444
PKTAT984_10450
MIUABE85_02430
ATERMW290_07550
BBAGE1O_00540
SHDSUTH_01213(fcbC1) SUTH_01666
EBAebA2752
ABREpbN1_13010 pbN1_17330
APETToN1_26790 ToN1_50290
AZOazo1929 azo2495(fcbC1) azo3044(ybgC)
AOAdqs_2084 dqs_2648 dqs_3178
AZAAZKH_1859(abmF) AZKH_4507
AZIAzCIB_1777 AzCIB_4625
ACOMCEW83_03870
AZDCDA09_22680
AZRCJ010_12615 CJ010_15705 CJ010_18845
TMZTmz1t_2489
TCLTchl_0786 Tchl_2975
THKCCZ27_17820
TAKTharo_0850 Tharo_1869
DDZDSYM_08570
DTOTOL2_C37360
DMMdnm_074430
ADEAdeh_0740
ACPA2cp1_0777
ANKAnaeK_0777
VINAKJ08_2653
SCLsce1756(fcbC)
SCUSCE1572_10950
CCROCMC5_031430
SAMYDB32_003306
LLUAKJ09_08412
MRMA7982_12749
HOHHoch_2192
MESRFGU64_17590
MESOBSQ44_21450
HOEIMCC20628_01410
AAKAA2016_5727
AMIHCO731_05565
RPODE0E05_11130
NIYFQ775_02910 FQ775_11405 FQ775_21475
KMNHW532_10745
SIXBSY16_4356
EAHFA04_32455
ESJSJ05684_b42890
ARUIG6M88_19290
AVQHRR99_19105
RTRRTCIAT899_CH14285
RJGCCGE525_16505
RHRCKA34_17190
NGLRG1141_CH38300
NGGRG540_CH38950
NEOCYG48_14445
ABAWD5400_06480 D5400_06530
PSCQKHQ08_01195
BJAblr3414(blr3414) blr7847(blr7847)
BJUBJ6T_62370 BJ6T_84700
BJPRN69_30230 RN69_40930
BRABRADO0965
BBTBBta_3245 BBta_7090
BRSS23_09410
AOLS58_66640
BRCBCCGELA001_33020
BRADBF49_4142
BICLMTR13_35495
BROBRAD285_0461
BRKCWS35_02965
BOTCIT37_06585
BRQCIT40_28190
BGQX265_33290
BGZXH91_22365 XH91_31690
BSYMCIT39_27205
BBETF8237_19620
BARHWN72_05950
BVZBRAD3257_8269
BELBE61_14340
BDGLPJ38_00695
BSEPHAP48_0019040
BQBJ4P68_0022535 J4P68_0034490
RPARPA1788
RPDRPD_1888
RPERPE_3801
RPTRpal_1990
RPXRpdx1_3744
VGOGJW-30_1_03657
AZCAZC_3186
MNOMnod_6462
MAQUMaq22A_c00755(fcbC)
MEEDA075_12460
METIDK427_23560
MTEADK419_20365
MINDmvi_14920
MIVC4E04_10970
MICOGDR74_09785
RHZRHPLAN_69970
PHLKKY_2322
DEQXM25_21580
DEIC4375_05475
DSALK1X15_01030
MMYRMXMO3_02952
YTIFNA67_03030
BVRBVIR_1678
BLAGBLTE_16380
PLEOOHA_1_04276
MMEDMame_00666 Mame_00668
BRND1F64_22330
PSINCAK95_06190 CAK95_08370
RBMTEF_11260
PSFPSE_3158
LAPACP90_18540
LABPFJ695_16655
LABTFIU93_25200 FIU93_30155
LAGGB0E33_02310 B0E33_30180
PSTGE8M01_13655
BNEDA69_02060
TSVDSM104635_00124
SILSPO0786 SPO1457
SITTM1040_2232
RUTFIU92_22430
JANJann_0674 Jann_1329
RPONG3256_00165
PGAPGA1_c33890
PGLPGA2_c32100
PGDGal_03454
PHPPhaeoP97_00058
PPICPhaeoP14_03194
PHQD1820_11820
LMDMETH_19590
LAQUR2C4_18630
CIDP73_0182
CEHCEW89_04065 CEW89_04080
MALGMALG_04444
YPACCEW88_22150 CEW88_22165
PABYGa0080574_TMP166 Ga0080574_TMP204
SUAMBOO69_03865 BOO69_15560 BOO69_19305
SULZC1J03_02560 C1J03_04355
SULIC1J05_03635
SULDB5M07_15285 B5M07_18450
SMEDJNX03_15530 JNX03_19560
SINLDSM14862_04308
TOMBWR18_13925 BWR18_14095
RIDRIdsm_00629 RIdsm_02009
AHTANTHELSMS3_04340
SAGUCDO87_17750
THAACFI11_04650
OCDFHY55_19190 FHY55_19280
ROTFIV09_19065
MALUKU6B_15610 KU6B_38030 KU6B_60090
TGLHFZ77_06775
RBLB6K69_12470
PDEPden_5092
PZHCX676_10745 CX676_14740
PAROCUV01_10710
PARUCYR75_14010
PARSDRW48_06105
PARREOJ32_00490
PKDF8A10_20330
PPANESD82_07030 ESD82_10165
PSANHGN31_04510
PMAUCP157_00367
PTPRCA23_c19050
RMBK529_002700
LVSLOKVESSMR4R_03933
GEHHYN69_07140 HYN69_07225
GFUKM031_16680
TAWEI545_11350 EI545_11460
SALOEF888_02370
SEDIEBB79_19915
BOOE2K80_00545
PSEBEOK75_00180
PPRUFDP22_11895 FDP22_18955
MONG8E03_06685
POZI0K15_07935
PALWPSAL_021490 PSAL_021520
HDHG5B40_19730
GCEKYE46_05195
NSMJO391_13000 JO391_13120
MMRMmar10_2690
CBOTATE48_08955
NPPPP1Y_AT11643
NREBES08_24460
NOVTQ38_007520
NDRHT578_07500
SPHPLH20_14110
SGISGRAN_0822
SPHOC3E99_00500
SPHXE5675_18065
SWISwit_0821
SPHDHY78_22590
SPHITS85_01650 TS85_07575 TS85_07890
SSANNX02_11380
SPLKAV944_07740
SPHCCVN68_17360
SPAUDRN02_014250
SECHB18_16520
SPAPH3Z74_18235
SSYSLG_12450
SPHTK426_11445
SHYDCJD35_17615
SCLOSCLO_1003250
SPYGYGS_C2P0410
BLASBSY18_661
BFWB5J99_12490
SMICSmB9_25200
AMXAM2010_2425
ERKCD351_08200
SRFLHU95_07250
AZLAZL_d05120
ALIAZOLI_p40108
ATIAL072_23335
AZMDM194_23810
AZZDEW08_02985 DEW08_29210 DEW08_29410
AOZHUE56_05985
NAOY958_15245
MAGamb0177
MAGXXM1_0600 XM1_1072 XM1_2264
MAGNWV31_11530 WV31_13535
FERFNB15_11985
TXITH3_13995
THACCSC3H3_21320
TIIDY252_07870 DY252_19285
ECOGFIV45_00675
BCUBCAH820_3039
BTWBF38_4198
BNTGSN03_14695
BACOOXB_0833
BACQDOE78_09045
PARHI5S86_22475(ybgC)
BAGBcoa_1582
BKWBkAM31D_23375
VIGBKP57_15260
PBUTDTO10_22335
PNPIJ22_51850
SALUDC74_825
SALLSAZ_04655
SCADDN051_01380
ASUNKG104_08850
AHMTL08_05035
AGLPYTT_2552
MEAPMTHMO_0368
LILLA_3529
LAJA0128_05635
LKBLPTSP3_g03340 LPTSP3_g37400
GAUGAU_3270
GPHGEMMAAP_16730
GGRHKW67_22155
HMTMTP16_20090
FINKQS_01635
FATDVK85_10685
FPALHYN49_11390
FMGHYN48_11320
FALBHYN59_11915
FSNGS03_02245
FAKFUA48_13795
FSDLXD69_15385
HHBHhub_2436
HNOLT974_08720
HALGHUG10_18625
HALUHUG12_20460
HACBHbl1158_15195 Hbl1158_15290
NAYHYG81_22795
HLRHALLA_02100 HALLA_19905
NAJB1756_12970
 » show all
Reference
1  [PMID:1610806]
  Authors
Chang KH, Liang PH, Beck W, Scholten JD, Dunaway-Mariano D
  Title
Isolation and characterization of the three polypeptide components of 4-chlorobenzoate dehalogenase from Pseudomonas sp. strain CBS-3.
  Journal
Biochemistry 31:5605-10 (1992)
DOI:10.1021/bi00139a025
  Sequence
Reference
2  [PMID:7765837]
  Authors
Dunaway-Mariano D, Babbitt PC
  Title
On the origins and functions of the enzymes of the 4-chlorobenzoate to 4-hydroxybenzoate converting pathway.
  Journal
Biodegradation 5:259-76 (1994)
DOI:10.1007/BF00696464
Other DBs
ExplorEnz - The Enzyme Database: 3.1.2.23
IUBMB Enzyme Nomenclature: 3.1.2.23
ExPASy - ENZYME nomenclature database: 3.1.2.23
UM-BBD (Biocatalysis/Biodegradation Database): 3.1.2.23
BRENDA, the Enzyme Database: 3.1.2.23
CAS: 141583-19-9

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