| Entry |
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| Name |
4-hydroxybenzoyl-CoA thioesterase
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| Class |
Hydrolases;
Acting on ester bonds;
Thioester hydrolases
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| Sysname |
4-hydroxybenzoyl-CoA hydrolase
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| Reaction(IUBMB) |
4-hydroxybenzoyl-CoA + H2O = 4-hydroxybenzoate + CoA [RN: R01301]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
This enzyme is part of the bacterial 2,4-dichlorobenzoate degradation pathway.
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| History |
EC 3.1.2.23 created 1999
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| Pathway |
| ec00130 | Ubiquinone and other terpenoid-quinone biosynthesis |
| ec01110 | Biosynthesis of secondary metabolites |
| ec01120 | Microbial metabolism in diverse environments |
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| Orthology |
| K01075 | 4-hydroxybenzoyl-CoA thioesterase |
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| Genes |
| PAEB: | NCGM1900_1747(ybgC) |
| PCQ: | PcP3B5_17220(ybgC_1) |
| PMOS: | O165_001105 O165_011230 |
| PPRC: | PFLCHA0_c47420(ybgC) |
| PFN: | HZ99_07205 HZ99_10605 |
| PMUD: | NCTC8068_04083(ybgC) |
| PFW: | PF1751_v1c44060(ybgC) |
| PTRT: | HU722_0014825 HU722_0023435(ybgC) |
| PTAE: | NCTC10697_03206(ybgC) |
| PKJ: | Q1W70_16510(ybgC) Q1W70_23480 |
| PMOR: | PMm318_A00150(ybgC) |
| PKH: | JLK41_06640(ybgC) JLK41_15645 |
| PSED: | DM292_04695(ybgC) DM292_17545 |
| AVN: | Avin_14220 Avin_36680(ybgC) |
| AVL: | AvCA_14220 AvCA_36680(ybgC) |
| AVD: | AvCA6_14220 AvCA6_36680(ybgC) |
| MII: | BTJ40_03680(ybgC) BTJ40_10620 |
| MICT: | FIU95_03620(ybgC) FIU95_09570 |
| CBRV: | R0137_01150 R0137_05130(ybgC) |
| HAK: | KO116_00194 KO116_00936 |
| HCAM: | I4484_07600 I4484_11070(ybgC) I4484_15235 |
| HAMC: | HNO52_10525(ybgC) HNO52_12250 HNO52_15085 |
| VRS: | V8F66_17390 V8F66_21015 |
| HSX: | HNO51_07010 HNO51_10775(ybgC) HNO51_15155 |
| HTX: | EKK97_12055(ybgC) EKK97_17075 |
| HSV: | HNO53_10060(ybgC) HNO53_15665 |
| ALCA: | ASALC70_00858(ybgC_1) |
| RPU: | CDC45_09395 CDC45_17775 |
| RNC: | GO999_08765 GO999_22550 |
| RSM: | CMR15_11834 CMR15_mp10040 |
| RPJ: | N234_03105 N234_14065 N234_23135 |
| REH: | H16_A2456(h16_A2456) |
| CNC: | CNE_1c23650 CNE_2c20780 |
| CUH: | BJN34_13170 BJN34_23985 BJN34_29265 |
| CTI: | RALTA_A1987 RALTA_B0114 |
| CBW: | RR42_m2746 RR42_s0687 |
| CUK: | KB879_15770 KB879_24180 |
| CNAN: | A2G96_15665 A2G96_30305 |
| BYI: | BYI23_A013610 BYI23_D000280 BYI23_D002080 |
| BURT: | BTHE68_56940 BTHE68_61440 |
| BUZ: | AYM40_28285 AYM40_34350 |
| PHS: | C2L64_12775 C2L64_18740 |
| PTER: | C2L65_16575 C2L65_27695 |
| PAZZ: | PBP221_56710 PBP221_82140 |
| PPK: | U875_07415 U875_07760 |
| PPNO: | DA70_00060 DA70_00455 |
| PPNM: | LV28_05860 LV28_06215 |
| PPUL: | RO07_00205 RO07_24810 |
| PAPI: | SG18_00500 SG18_14780 SG18_23380 |
| PTX: | ABW99_11395 ABW99_15295 |
| PNR: | AT302_15615 AT302_16705 |
| PLG: | NCTC10937_01537(ybgC) |
| CABK: | NK8_53030 NK8_79250 |
| BUE: | BRPE67_ACDS14030 BRPE67_DCDS02310 BRPE67_DCDS03830 |
| TVL: | FAZ95_23535 FAZ95_29450 |
| AXY: | AXYL_00589 AXYL_02928 |
| AXX: | ERS451415_00592(fadM_1) |
| AIS: | BUW96_04725 BUW96_05675 BUW96_22900 |
| PIG: | EGT29_06000 EGT29_09025 EGT29_22810 |
| POL: | Bpro_0588 Bpro_3115 Bpro_4124 |
| VAP: | Vapar_0657 Vapar_1512 Vapar_3916 |
| VPE: | Varpa_1667 Varpa_4528 |
| VPD: | VAPA_1c16040 VAPA_1c40390 |
| VBO: | CKY39_09095 CKY39_24995 |
| VAM: | C4F17_10830 C4F17_30250 |
| VAZ: | H7F35_02895 H7F35_20665 |
| VAV: | IG196_06835 IG196_22075 |
| VAE: | RZE79_08245 RZE79_23160 RZE79_31965 |
| VAW: | SFB74_09360 SFB74_23860 |
| HRB: | Hrubri_3964 Hrubri_4428 |
| SHD: | SUTH_01213(fcbC1) SUTH_01666 |
| ABRE: | pbN1_13010 pbN1_17330 |
| APET: | ToN1_26790 ToN1_50290 |
| AZO: | azo1929 azo2495(fcbC1) azo3044(ybgC) |
| AOA: | dqs_2084 dqs_2648 dqs_3178 |
| AZA: | AZKH_1859(abmF) AZKH_4507 |
| AZI: | AzCIB_1777 AzCIB_4625 |
| AZR: | CJ010_12615 CJ010_15705 CJ010_18845 |
| TAK: | Tharo_0850 Tharo_1869 |
| NIY: | FQ775_02910 FQ775_11405 FQ775_21475 |
| ABAW: | D5400_06480 D5400_06530 |
| BJA: | blr3414(blr3414) blr7847(blr7847) |
| BJU: | BJ6T_62370 BJ6T_84700 |
| BJP: | RN69_30230 RN69_40930 |
| BGZ: | XH91_22365 XH91_31690 |
| BQB: | J4P68_0022535 J4P68_0034490 |
| BBAN: | J4G43_019945 J4G43_047485 |
| BCOU: | IC761_29930 IC761_33320 |
| BXN: | I3J27_13620 I3J27_36080 |
| BRAZ: | LRP30_14905 LRP30_39465 |
| BOY: | LQG66_05115 LQG66_19980 |
| BGEA: | ACP2YP_04905 ACP2YP_15535 |
| BGEP: | ACP2YO_14580 ACP2YO_45690 |
| BRAB: | RX331_32465 RX331_35490 |
| PTAW: | DW352_04845 DW352_17155 DW352_26125 |
| MAQU: | Maq22A_c00755(fcbC) |
| MMED: | Mame_00666 Mame_00668 |
| PSIN: | CAK95_06190 CAK95_08370 |
| LABT: | FIU93_25200 FIU93_30155 |
| LAGG: | B0E33_02310 B0E33_30180 |
| RAGG: | QUB73_19315 QUB73_30225 |
| CEH: | CEW89_04065 CEW89_04080 |
| CBAK: | DA792_01365 DA792_01380 |
| YPAC: | CEW88_22150 CEW88_22165 |
| PABY: | Ga0080574_TMP166 Ga0080574_TMP204 |
| SUAM: | BOO69_03865 BOO69_15560 BOO69_19305 |
| SULZ: | C1J03_02560 C1J03_04355 |
| SULD: | B5M07_15285 B5M07_18450 |
| SMED: | JNX03_15530 JNX03_19560 |
| SUAL: | KDD17_00625 KDD17_02750 |
| TOM: | BWR18_13925 BWR18_14095 |
| RID: | RIdsm_00629 RIdsm_02009 |
| SSTL: | ABFK29_08875 ABFK29_22225 ABFK29_23600 |
| OCD: | FHY55_19190 FHY55_19280 |
| MALU: | KU6B_15610 KU6B_38030 KU6B_60090 |
| MATG: | ACMVPR_05605 ACMVPR_09895 |
| FYT: | QF092_08615 QF092_08730 |
| PZH: | CX676_10745 CX676_14740 |
| PPAN: | ESD82_07030 ESD82_10165 |
| GEH: | HYN69_07140 HYN69_07225 |
| TAW: | EI545_11350 EI545_11460 |
| PPRU: | FDP22_11895 FDP22_18955 |
| PALW: | PSAL_021490 PSAL_021520 |
| NSM: | JO391_13000 JO391_13120 |
| MANH: | LA6_005369 LA6_005372 |
| SPHI: | TS85_01650 TS85_07575 TS85_07890 |
| SBIN: | SBA_ch2_6260 SBA_pBAR1_750 |
| AZZ: | DEW08_02985 DEW08_29210 DEW08_29410 |
| MAGX: | XM1_0600 XM1_1072 XM1_2264 |
| MAGN: | WV31_11530 WV31_13535 |
| TII: | DY252_07870 DY252_19285 |
| THAI: | IT893_02190 IT893_13390 |
| TTB: | MACH01_04380 MACH01_26570 |
| PBRU: | LZC95_18000 LZC95_31230 |
| PRUE: | LVJ94_18350 LVJ94_30470 |
| LKB: | LPTSP3_g03340 LPTSP3_g37400 |
| LGOR: | AB3N59_14650 AB3N59_15475 |
| LCIN: | AB3N61_00510 AB3N61_13465 |
| FCJ: | RN605_01220 RN605_09920 |
| HACB: | Hbl1158_15195 Hbl1158_15290 |
| HLR: | HALLA_02100 HALLA_19905 |
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| Reference |
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| Authors |
Chang KH, Liang PH, Beck W, Scholten JD, Dunaway-Mariano D |
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| Title |
Isolation and characterization of the three polypeptide components of 4-chlorobenzoate dehalogenase from Pseudomonas sp. strain CBS-3. |
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| Journal |
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| Sequence |
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| Reference |
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| Authors |
Dunaway-Mariano D, Babbitt PC |
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| Title |
On the origins and functions of the enzymes of the 4-chlorobenzoate to 4-hydroxybenzoate converting pathway. |
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| Journal |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 3.1.2.23 |
| ExPASy - ENZYME nomenclature database: | 3.1.2.23 |
| UM-BBD (Biocatalysis/Biodegradation Database): | 3.1.2.23 |
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