KEGG   ENZYME: 3.1.21.4
Entry
EC 3.1.21.4                 Enzyme                                 
Name
type II site-specific deoxyribonuclease;
type II restriction enzyme
Class
Hydrolases;
Acting on ester bonds;
Endodeoxyribonucleases producing 5'-phosphomonoesters
Reaction(IUBMB)
Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates
Comment
This is a large group of enzymes which, together with those now listed as EC 3.1.21.3 (type 1 site-specific deoxyribonuclease) and EC 3.1.21.5.
History
EC 3.1.21.4 created 1984 from EC 3.1.23 and EC 3.1.24
Orthology
K01155  type II restriction enzyme
K21512  Escherichia phage terminase, large subunit
Genes
ECEZ1883
ECSECs_1630
ECFECH74115_1620
ETWECSP_1536
ELXCDCO157_1562
EOJECO26_0602
EOHECO103_0538
ECOOECRM13514_1822
EOKG2583_0692
ELRECO55CA74_03370
ELHETEC_1221
EUNUMNK88_1997
ECPECP_1167
ECOSEC958_1365
ECYECSE_2066
ECRECIAI1_1588(A) ECIAI1_4499
EUMECUMN_1416(A)
ECTECIAI39_1509(A)
EOCCE10_1812
EBLECD_10036(A)
EBEB21_00731(A)
EBDECBD_2873
EIHECOK1_0545
ECCc3173
ELOEC042_1699
ELNNRG857_05680
ECLEcolC_2091
EKFKO11_15050
ELWECW_m1703
ELLWFL_08355
ECOLLY180_08045
ECOIECOPMV1_00552
ECOJP423_06270
ESZFEM44_19610
SSNSSON_2430
SHQA0259_07705
YEEYE5303_30521
YCAF0T03_02125
HINHI_0512
TBVH9L17_10655
FAUFraau_1438
PARPsyc_0143(dpnC)
PCRPcryo_0153
PSOPSYCG_00970
PURAOC03_07185
PALIA3K91_0184
PSPGAK823_00900
PSYCDABAL43B_0175(dpnC)
PSYAAOT82_1635
PSYPE5677_12565
MCTMCR_0519
MCATMC25239_00529
MOIMOVS_02725
MCUNNCTC10297_00967
MNNI6G26_03115
MNSLU293_09740
SHNShewana3_4140
CZACYCME_0131
TSETHMIRHAS_19210
ENWMJO57_19280
BTHGMS2017_2153
IFOCVFO_1316
NMENMB0726 NMB1032(nlaIVR) NMB1289 NMB1896(dpnC)
NMDNMBG2136_0676
NMANMA1499
NMNNMCC_0324(drg)
NAQD0T90_03330
NBLGJV52_04765
NCINCTC10296_01548(drg)
NMUSH7A79_0634
NDULVJ88_05365
NMBMON40_12650
USULVJ78_00015
UTELVJ83_00520
RPIRpic_1724
RPFRpic12D_5341
RMERmet_6120(copL)
BYIBYI23_A025330
TATKUM_0834
RFRRfer_4209
PNAPnap_4564
AJSAjs_2679
ACKC380_06130
ADKAlide2_2717
DOEDENOEST_1706 DENOEST_1864
DSUDsui_1063
APETToN1_03050
HPYHP_0091 HP_0262 HP_1366
HEOC694_00445 C694_01325
HPJjhp_0246 jhp_1442
HPAHPAG1_0264
HPSHPSH_01365 HPSH_07070
HHPHPSH112_00440 HPSH112_01610 HPSH112_07165
HHQHPSH169_00435 HPSH169_01495
HHRHPSH417_00435 HPSH417_01325
HPGHPG27_241 HPG27_84
HPPHPP12_0094 HPP12_0261 HPP12_1174 HPP12_1390
HPLHPB8_127 HPB8_1300
HPCHPPC_01330
HCAHPPC18_01310
HPMHPSJM_01425
HPEHPELS_00475
HPOHMPREF4655_20010
HPIhp908_0275 hp908_1401
HPQhp2017_02682 hp2017_1355
HPWhp2018_02712 hp2018_1358(ecoRIb)
HPUHPCU_00425
HEFHPF16_0104 HPF16_0269
HPFHPF30_1034 HPF30_1170 HPF30_1286
HEQHPF32_0271
HEXHPF57_0315
HPTHPSAT_00425 HPSAT_01310
HPZHPKB_0104 HPKB_0273
HPVHPV225_1439
HPXHMPREF0462_0315
HENHPSNT_01495
HPHHPLT_01350
HPNHPIN_00435 HPIN_01180
HEPHPPN120_01325
HEUHPPN135_00465 HPPN135_01355 HPPN135_07160
HESHPSA_00475 HPSA_01325
HPYSHPSA20_0290
HCNHPB14_00445 HPB14_01295
HPDKHP_0260
HEYMWE_0183 MWE_0338
HERC695_00445 C695_01320
HEIC730_00445 C730_01325
HPYAHPAKL117_01305 HPAKL117_06780
HPYKHPAKL86_01620 HPAKL86_02540
HPYOHPOK113_0103 HPOK113_0271
HPYLHPOK310_0104 HPOK310_0266
HPYEHPOKI154_07060
HPYHHPOKI828_01420
HPYRK747_09995
HPYIK750_02880
HPYUK751_06130 K751_07180
HPYMK749_04345 K749_05095
HEMK748_02765 K748_03515
HEBU063_0255 U063_0435 U063_0602
HEZU064_0256 U064_0436 U064_0603
HACHac_0519(mjaVIP)
HFEHFELIS_11740
HBIHBZC1_02930 HBZC1_18460
HCEHCW_04935
HCMHCD_00680 HCD_02405
HCPHCN_0370
HCBHCBAA847_0387
HWIA0Z60_00300
SSEIFJR45_02225
CFTCFF04554_0318
CHACHAB381_1228
COJCORN_0104
CINFCINF_0824
SDLSdel_1531
ANTArnit_2984
ACLOACLO_0529
ARCABLL_1425
GPIGPICK_01050
GEOGeob_2517
DOLDole_3089
ANKAnaeK_3271
BBTBBta_p0135
BSEPHAP48_0009000
BQBJ4P68_0026675
XAUXaut_4599
MEAMex_2p0101
MDIMETDI1340
MCHMchl_1009
MPOMpop_2541
NOHG5V57_26365
CAKCaul_2312
BMEDGYM46_08965
BVITJIP62_10630
ZMPZymop_0098
NPPPP1Y_AT24187
SALSala_2432
SPHKSKP52_22895
SDHH9L15_07815
SJPSJA_C1-05270
SCHSphch_4091
SSYSLG_p_00490
GOHB932_3248
GXYGLX_30330
GXLH845_3472
APKAPA386B_1661
AOZHUE56_30345
BACIB1NLA3E_19510
GSTHW35_01470
NTMBTDUT50_05330
AIAAWH56_004250
SEPSDP17_55
SCARDWB96_07290
SDBCNQ82_02135 CNQ82_02140
SRAILN051_01080
MARYLAU42_02205
GHANCTC10459_00255(mboIR)
PSABPSAB_12850
PBDPBOR_17485
PSONJI735_35050
AFXJZ786_07105
SPNSP_1221 SP_1222 SP_1850(dpnC)
SPDSPD_1079 SPD_1080 SPD_1631
SPRspr1665(dpnC)
SPWSPCG_1824(dpnC)
SJJSPJ_1755
SNVSPNINV200_16700
SPXSPG_1733(dpnB)
SNTSPT_1767
SNDMYY_1745
SPNNT308_08385
SPVSPH_1964
SNCHMPREF0837_12073
SNMSP70585_1903
SPPSPP_1848
SNIINV104_15870
SPNGHMPREF1038_01817
SNBSP670_1923
SNPSPAP_1844
SNXSPNOXC16230
SNUSPNA45_00401(dpnC)
SPNESPN034156_06960
SPNMSPN994038_16150
SPNOSPN994039_16160
SMUSMU_506
SMCSmuNN2025_1466
SMUTSMUGS5_02195
SMJSMULJ23_1485
SMUASMUFR_0436
SSASSA_1716
SSTSSUST3_0037 SSUST3_0038
SSUYYB51_0180 YB51_0185
SSKSSUD12_0038 SSUD12_0039
SSQSSUD9_0036 SSUD9_0037
SDSSDEG_0953
SDAGGS_0921
SMBsmi_0526
SANCSANR_0703
SANSDK43_06655
SRQSR187_8185(dpnII)
SVBNCTC12167_00979(mboIR)
SFERNCTC12278_00538(mboIR) NCTC12278_01499
SOSINT76_06910
LZHD1B17_01495
LGEC269_06475
WEIEQG49_11810
CSRCspa_c40500(dpnB)
AOEClos_1062
CTHCthe_1512
CTXClo1313_2274
RHEREHE19_010910
ESUEUS_22060
RALRumal_0668
ROBCK5_08200
EELEUBELI_01767
ERTEUR_02470
PHXKGNDJEFE_00423(dpnB)
FMSM1R53_06345
TEXTeth514_0459
THXThet_0507
TPDTeth39_1776
TITThit_0486
TBOThebr_1821
TKITKV_c04880(mjaIIIR)
CHYCHY_2211
CKNCalkro_2540
KMEH0A61_01260(dpnB)
CAZOG3A45_10905
ECOUM1R54_04675
MEDMELS_0976
SSGSelsp_0626
MFUNGXM21_03600
EIOH9L01_05425
CMITNQ499_06240
MCDMCRO_0752
MSSMSU_0849(dpnII)
MANSFRW55_03345
MMIOHLA92_02875
MCOUNCTC10179_00204(dpnB)
MALMAGa2710
MFRMFE_01240(dpnII)
MFMMfeM64YM_0146(dpnII)
MFPMBIO_0191
MANIDP067_00055
MFELJPM2_7090
PALPA0777(rsrIR)
NZSSLY_1011
ACLACL_1082(dpnII)
APALBN85400320(dpnII)
SCRSCHRY_v1c06730
SSYRSSYRP_v1c06950
SAPISAPIS_v1c04340
SMOOSMONO_v1c05100
MALANCTC10135_00706(rsrIR)
CGACelgi_0121
AUSIPK37_07230
APIING665_06360
MCUHMPREF0573_11642
SYNESyn6312_0850
SYNPSyn7502_02127
CMPCha6605_1951
MARMAE_08660
LFSHFV01_04035
ANAall3631(avaIR)
NEDHUN01_23770
ANBANA_C11060
DLYDehly_0468
ATMANT_07640
DGEDgeo_2577
AMUAmuc_0062 Amuc_1564
LUOHHL09_09830
AMUCPan181_21670(rsrIR)
TSUTresu_1694
TRMJO41_08570
TRIDYE50_05450 DYE50_05455
SCCSpico_0553
BRMBmur_0842
FNCHMPREF0946_02035
TLITlie_0307
BFRBF2023
BZGC4H11_02725
BUNBun01g_13860 Bun01g_27450
BSTEK6V31_04685
BVUBVU_3992
BSABacsa_2065
PCOPI6J50_08430
PGNPGN_1425
PDIBDI_3253
BVSBARVI_06925
COPRCop2CBH44_01370 Cop2CBH44_21110
PDTPrede_2009
PHISJ5A62_11685
APUTL6V35_06385
MGOSDIU38_022660
MGIKGO620_003585
BBDBelba_2975
SLISlin_6658 Slin_6905
RSIRunsl_4415 Runsl_5934
FAEFAES_pFAES01119
HYMN008_21360
HYDPK28_18490
MTTFtrac_0428
FPSFP2273(hpaIIR)
FJOFjoh_3075
ZPRZPR_4244
SABUMBM09_12125
RANRiean_1467 Riean_1818
RAIRA0C_0017 RA0C_1747
RARRIA_0344 RIA_0741
RAGB739_0012 B739_0404
RAEG148_0085 G148_1739
RATM949_0441
ESTEHNV03_01185
IALIALB_2630
HTHHTH_0222
HTEHydth_0221
SULSYO3AOP1_1591
SAFSULAZ_0051
DTEDester_0101
TMETmel_0307 Tmel_1481
FNOFnod_0526
FPEFerpe_1710
CPOCOPRO5265_1446
CNICalni_0428
MSCHN508_001213(dpnB)
DTHDICTH_1799
TYETHEYE_A0736
DTPJZK55_07830
ALAMRT761_00144(dpnB)
MJAMJ_0600
MIGMetig_1784
MOKMetok_0256
MEBAbm4_1017
METHMBMB1_0501
TCQTIRI35C_1370
HSINKDQ40_17260
NSALHWV07_08745
THBN186_01200
 » show all
Reference
1  [PMID:2159140]
  Authors
Roberts RJ.
  Title
Restriction enzymes and their isoschizomers.
  Journal
Nucleic Acids Res 18 Suppl:2331-65 (1990)
DOI:10.1093/nar/18.suppl.2331
Other DBs
ExplorEnz - The Enzyme Database: 3.1.21.4
IUBMB Enzyme Nomenclature: 3.1.21.4
ExPASy - ENZYME nomenclature database: 3.1.21.4
BRENDA, the Enzyme Database: 3.1.21.4
CAS: 9075-08-5

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