KEGG   ENZYME: 3.1.3.24
Entry
EC 3.1.3.24                 Enzyme                                 

Name
sucrose-phosphate phosphatase;
sucrose 6-phosphate hydrolase;
sucrose-phosphate hydrolase;
sucrose-phosphate phosphohydrolase;
sucrose-6-phosphatase;
sucrose phosphatase;
sucrose-6-phosphate phosphatase;
SPP
Class
Hydrolases;
Acting on ester bonds;
Phosphoric-monoester hydrolases
Sysname
sucrose-6F-phosphate phosphohydrolase
Reaction(IUBMB)
sucrose 6F-phosphate + H2O = sucrose + phosphate [RN:R00805 R06211]
Reaction(KEGG)
R00805 R06211(G)
Substrate
sucrose 6F-phosphate [CPD:C02591];
H2O [CPD:C00001]
Product
sucrose [CPD:C00089];
phosphate [CPD:C00009]
Comment
Requires Mg2+ for maximal activity [2]. This is the final step in the sucrose-biosynthesis pathway. The enzyme is highly specific for sucrose 6-phosphate, with fructose 6-phosphate unable to act as a substrate [2]. Belongs in the haloacid dehydrogenase (HAD) superfamily. The F of sucrose 6F-phosphate is used to indicate that the fructose residue of sucrose carries the substituent.
History
EC 3.1.3.24 created 1972, modified 2008
Pathway
ec00500  Starch and sucrose metabolism
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K07024  sucrose-6-phosphatase
Genes
ATH: AT1G51420(SPP1) AT2G35840 AT3G52340(SPP2) AT3G54270
ALY: 9313927 9314033 9315646 9330377
CRB: 17885437 17885460 17888311 17897904
CSAT: 104711347 104711786 104712007 104712793 104713932 104742656 104758452 104778051 104781077 104781293 104781996 104785950 104791485 104791699 104792218 104792360
EUS: EUTSA_v10010361mg EUTSA_v10010402mg EUTSA_v10011514mg EUTSA_v10016712mg EUTSA_v10023476mg
BRP: 103832861 103841339 103857590 103863242 103863471 103865486 103868568
BNA: 106366954 106384344 106384425 106384664 106384744 106388145 106390094 106391426 106394386 106411802 106412074 106417948 106430593 106430595 106431371 106437864 106439027 106449288 106449368 111208044
BOE: 106309682 106328025 106328735 106340346 106341229 106342543
RSZ: 108819311 108847325 108849559 108849616 108853936 108857233 108858730 108859954
THJ: 104808403 104811340
CPAP: 110816808
CIT: 102613091
CIC: CICLE_v10011822mg CICLE_v10015425mg
TCC: 18586901 18598461
GRA: 105766586 105770662
GHI: 107893582 107899194 107904387 107948519
GAB: 108453353 108460850
DZI: 111293650 111310424 111311629
EGR: 104446642 104454069
GMX: 100796915 100800397
GSJ: 114372119 114403740
PVU: PHAVU_007G233700g PHAVU_007G265500g
VRA: 106769690 106770962
VAR: 108318780 108323637 108326002 108332934
VUN: 114190059 114192146
CCAJ: 109794427 109813367
MTR: MTR_1g040560 MTR_1g054980
CAM: 101495120 101505023
LJA: Lj0g3v0007959.1(Lj0g3v0007959.1) Lj0g3v0007959.2(Lj0g3v0007959.2) Lj0g3v0259849.1(Lj0g3v0259849.1) Lj6g3v0145980.1(Lj6g3v0145980.1) Lj6g3v0156190.1(Lj6g3v0156190.1) Lj6g3v0156190.2(Lj6g3v0156190.2)
ADU: 107470592 107476034
AIP: 107623437 107626301
LANG: 109325807 109325808 109336456
FVE: 101300366 101312086
RCN: 112182942 112192942
PPER: 18770457 18775718
PMUM: 103336602 103339575
PAVI: 110749204 110758071
MDM: 103408838 103418485 103430254 103454193
PXB: 103940216 103946089 103946090 103952711
ZJU: 107433599 107435862
CSV: 101205644 101212615
CMO: 103486711 103489356
MCHA: 111018765 111019350
CMAX: 111467778 111498604
CMOS: 111441900 111449724
CPEP: 111800682 111801786
RCU: 8259817
JCU: 105635774 105643873
HBR: 110653619 110655835
MESC: 110621424 110622142 110625179
POP: 7469925 7479489 7490873
PEU: 105131608 105138205 105141578
JRE: 109013498 109015998
QSU: 111991104
VVI: 100258115 100267521
SLY: 543710 778279
SPEN: 107002529 107009907
SOT: 102577786(SPP2)
CANN: 107854535 107874940
NTA: 107767908(NtSPP1) 107819363(NtSPP2) 107828694 107830739
NSY: 104221533 104224388
NTO: 104101716 104121433
NAU: 109214337
INI: 109181503
SIND: 105161697 105173967
OEU: 111366032 111412291
HAN: 110880252 110904344
LSV: 111899801 111916621
CCAV: 112516457 112519430
DCR: 108206327 108216063 108223892
BVG: 104893197 104907189
SOE: 110784542 110798139
CQI: 110688864 110724572 110737398 110739865
NNU: 104605199
PSOM: 113300334 113306837 113307747 113310687 113314020 113322703 113337446
OSA: 4325448 4328274 4337789
DOSA: Os01t0376700-01(Os01g0376700) Os02t0143100-01(Os02g0143100)
OBR: 102701032 102708121 102714559
BDI: 100829936 100832864
ATS: 109757507 109762595
SBI: 8056063 8069481 8075958
ZMA: 541868(spp1) 542661
SITA: 101753890 101754411 101774746
PDA: 103707401 103719698
EGU: 105042413 105059936
MUS: 103971455 103993085
DCT: 110107244
PEQ: 110028814
AOF: 109820022 109828864
ATR: 18421607
SMO: SELMODRAFT_121516 SELMODRAFT_182236 SELMODRAFT_236983 SELMODRAFT_402942 SELMODRAFT_410141
PPP: 112275244 112276303 112287275 112291548
MNG: MNEG_4690
CSL: COCSUDRAFT_15248
CVR: CHLNCDRAFT_53400
APRO: F751_1470
CPV: cgd6_2840
CHO: Chro.60329
TGO: TGME49_217850
GTT: GUITHDRAFT_114736 GUITHDRAFT_115146
VSH: BSZ05_23475
VTA: B0839
VCC: FAZ90_09365
METL: U737_05515
MBUR: EQU24_03050
TCX: Tcr_1795
HTR: EPV75_09715
HMAR: HVMH_0657
THIO: AYJ59_03305 AYJ59_04275
THIG: FE785_04525
TZO: THMIRHAT_22250
NHL: Nhal_2558
NWA: Nwat_2809
NWR: E3U44_09995
ALV: Alvin_0251
TVI: Thivi_1157
THIP: N838_02215
HAZ: A9404_10340
GAI: IMCC3135_06960
GHL: GM160_01010
TTC: FOKN1_2844
HOL: HORIV_03720
RAC: RA876_16680
SIMP: C6571_13440
TIN: Tint_2684
THI: THI_3226
SNIV: SFSGTM_16980
DEU: DBW_2298(mfppA)
DWD: DSCW_55820
LAGG: B0E33_03125
LABR: CHH27_00885
LABT: FIU93_26000(mfppA)
PBR: PB2503_13414
MGM: Mmc1_2291 Mmc1_3515
MAES: Ga0123461_1717
BACO: OXB_3530
LYG: C1N55_13945
PSYH: D0S48_01690
ASOC: CB4_03629(mfppA)
KYR: CVV65_03215
SSIL: SOLI23_18030
PLN: Plano_0410
PRT: AUC31_07610
PLL: I858_005325
PANA: BBH88_00325
PDG: BCM40_13665
PHC: BBI08_15055
PMAR: B0X71_02580
PPLA: BBI15_14410
PFAE: AJGP001_02575
PLX: CW734_03755
PMAT: BBI11_03505
PDEC: H1Q58_02650
SPOR: SporoP33_05635
SPOP: SporoP37_06125
RST: ATY39_08965
PLAY: DNR44_000870
PTH: PTH_0618(Cof)
STHR: BXT84_11770
SYN: slr0953
SYZ: MYO_118620
SYY: SYNGTS_1845(slr0953)
SYT: SYNGTI_1845(slr0953)
SYS: SYNPCCN_1844(slr0953)
SYQ: SYNPCCP_1844(slr0953)
SYJ: D082_32810
SYO: C7I86_09605
SYP: SYNPCC7002_A0887
SYV: AWQ23_04595
SYL: AWQ21_05190
DSL: Dacsa_0649
CMP: Cha6605_0297
LEN: LEP3755_41890
LET: O77CONTIG1_04515(mfppA)
LBO: LBWT_43300
AMR: AM1_2884(spp)
THEU: HPC62_07905
GLP: Glo7428_0776
CHON: NIES4102_31360
HAO: PCC7418_1364
ENN: FRE64_03350
CYT: cce_1207(sps)
CYC: PCC7424_4476
CYJ: Cyan7822_2392
CYN: Cyan7425_4592
MIC: Mic7113_1367
OXY: HCG48_05550
GEI: GEI7407_1610
OAC: Oscil6304_5556
ONI: Osc7112_3132
MPRO: BJP34_15325
CEP: Cri9333_1967
GVI: gll3839
GLJ: GKIL_4106
ANA: all0376
NPU: Npun_F3066 Npun_R3569
NOS: Nos7107_4134
NOP: Nos7524_0250
NON: NOS3756_02770
NFL: COO91_04164
NOE: CLI64_22925
NSH: GXM_02276 GXM_09606
NED: HUN01_11595 HUN01_32555
AVA: Ava_2821
NAZ: Aazo_2470
ANB: ANA_C10157 ANA_C12946
ACY: Anacy_4941
AWA: AA650_15310 AA650_21190
ANN: EH233_21550
CSG: Cylst_0594
CALO: Cal7507_2549
CALT: Cal6303_0610
CALH: IJ00_04815
RIV: Riv7116_6091
FIS: FIS3754_12960
DOU: BMF77_02685(mfppA_1) BMF77_04436(mfppA_3)
DFS: HGD76_01200 HGD76_03985
CCUR: IAR63_05280
TOQ: HCG51_27175
NCN: BZZ01_32000
CTHE: Chro_0680
PLP: Ple7327_3241
SCS: Sta7437_2821
STAN: STA3757_07510
LUO: HHL09_01620
RUL: UC8_59070(mfppA)
AHEL: Q31a_06240(mfppA)
BVO: Pan97_31840(mfppA)
FMR: Fuma_03288(mfppA)
PLON: Pla110_03550(mfppA)
SSM: Spirs_0902
SLR: L21SP2_2635
POB: LPB03_05965
PRN: BW723_17540
AHZ: APS56_07830
SEON: BWZ22_10920
TAJ: C1A40_11725
MARF: CJ739_417
 » show all
Reference
1  [PMID:4290548]
  Authors
Hawker JS, Hatch MD.
  Title
A specific sucrose phosphatase from plant tissues.
  Journal
Biochem J 99:102-7 (1966)
DOI:10.1042/bj0990102
Reference
2  [PMID:11050182]
  Authors
Lunn JE, Ashton AR, Hatch MD, Heldt HW
  Title
Purification, molecular cloning, and sequence analysis of sucrose-6F-phosphate phosphohydrolase from plants.
  Journal
Proc Natl Acad Sci U S A 97:12914-9 (2000)
DOI:10.1073/pnas.230430197
  Sequence
[zma:541868] [osa:4328274] [ath:AT2G35840 AT3G54270]
Reference
3  [PMID:12753969]
  Authors
Lunn JE, MacRae E
  Title
New complexities in the synthesis of sucrose.
  Journal
Curr Opin Plant Biol 6:208-14 (2003)
DOI:10.1016/S1369-5266(03)00033-5
Reference
4  [PMID:15937230]
  Authors
Fieulaine S, Lunn JE, Borel F, Ferrer JL
  Title
The structure of a cyanobacterial sucrose-phosphatase reveals the sugar tongs that release free sucrose in the cell.
  Journal
Plant Cell 17:2049-58 (2005)
DOI:10.1105/tpc.105.031229
Other DBs
ExplorEnz - The Enzyme Database: 3.1.3.24
IUBMB Enzyme Nomenclature: 3.1.3.24
ExPASy - ENZYME nomenclature database: 3.1.3.24
BRENDA, the Enzyme Database: 3.1.3.24
CAS: 9059-33-0

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Gene (817)   
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