KEGG   ENZYME: 3.1.3.24
Entry
EC 3.1.3.24                 Enzyme                                 
Name
sucrose-phosphate phosphatase;
sucrose 6-phosphate hydrolase;
sucrose-phosphate hydrolase;
sucrose-phosphate phosphohydrolase;
sucrose-6-phosphatase;
sucrose phosphatase;
sucrose-6-phosphate phosphatase;
SPP
Class
Hydrolases;
Acting on ester bonds;
Phosphoric-monoester hydrolases
Sysname
sucrose-6F-phosphate phosphohydrolase
Reaction(IUBMB)
sucrose 6F-phosphate + H2O = sucrose + phosphate [RN:R00805 R06211]
Reaction(KEGG)
R00805 R06211(G)
Substrate
sucrose 6F-phosphate [CPD:C02591];
H2O [CPD:C00001]
Product
sucrose [CPD:C00089];
phosphate [CPD:C00009]
Comment
Requires Mg2+ for maximal activity [2]. This is the final step in the sucrose-biosynthesis pathway. The enzyme is highly specific for sucrose 6-phosphate, with fructose 6-phosphate unable to act as a substrate [2]. Belongs in the haloacid dehydrogenase (HAD) superfamily. The F of sucrose 6F-phosphate is used to indicate that the fructose residue of sucrose carries the substituent.
History
EC 3.1.3.24 created 1972, modified 2008
Pathway
ec00500  Starch and sucrose metabolism
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K07024  sucrose-6-phosphatase
Genes
ATHAT1G51420(SPP1) AT2G35840 AT3G52340(SPP2) AT3G54270
ALY9313927 9314033 9315646 9330377
CRB17885437 17885460 17888311 17897904
CSAT104711347 104711786 104712007 104712793 104713932 104742656 104758452 104778051 104781077 104781293 104781996 104785950 104791485 104791699 104792218 104792360
EUSEUTSA_v10010361mg EUTSA_v10010402mg EUTSA_v10011514mg EUTSA_v10016712mg EUTSA_v10023476mg
BRP103832861 103841339 103857590 103863242 103863471 103865486 103868568
BNA106366954 106384344 106384425 106384664 106384744 106388145 106390094 106391426 106394386 106411802 106412074 106417948 106430593 106430595 106431371 106437864 106439027 106449288 106449368 111208044
BOE106309682 106328025 106328735 106340346 106341229 106342543
RSZ108819311 108847325 108849559 108849616 108853936 108857233 108858730 108859954
THJ104808403 104811340
CPAP110816808
CIT102613091
CICCICLE_v10011822mg CICLE_v10015425mg
PVY116106042 116129816
MINC123192306 123216387
TCC18586901 18598461
GRA105766586 105770662
GHI107893582 107899194 107904387 121217938
GAB108453353 108460850
DZI111293650 111310424 111311629
EGR104446642 104454069
GMX100796915 100800397
GSJ114372119 114403740
PVUPHAVU_007G233700g PHAVU_007G265500g
VRA106769690 106770962
VAR108318780 108323637 108326002 108332934
VUN114190059 114192146
CCAJ109794427 109813367
APRC113871066 113873679
MTRMTR_1g040560 MTR_1g054980
CAM101495120 101505023
LJALj0g3v0007959.1(Lj0g3v0007959.1) Lj0g3v0007959.2(Lj0g3v0007959.2) Lj0g3v0259849.1(Lj0g3v0259849.1) Lj6g3v0145980.1(Lj6g3v0145980.1) Lj6g3v0156190.1(Lj6g3v0156190.1) Lj6g3v0156190.2(Lj6g3v0156190.2)
ADU107470592 107476034
AIP107623437 107626301
AHF112716015 112728709 112757332 112784279
LANG109325807 109325808 109336456
FVE101300366 101312086
RCN112182942 112192942
PPER18770457 18775718
PMUM103336602 103339575
PAVI110749204 110758071
PDUL117628203 117635052
MDM103408838 103418485 103430254 103454193
PXB103940216 103946089 103946090 103952711
ZJU107433599 107435862
MNT21389873 21403135
CSV101205644 101212615
CMO103486711 103489356
BHJ120081542 120091771
MCHA111018765 111019350
CMAX111467778 111498604
CMOS111441900 111449724
CPEP111800682 111801786
RCU8259817
JCU105635774
HBR110653619 110655835
MESC110621424 110622142 110625179
POP7469925 7479489 7490873
PEU105131608 105138205 105141578
PALZ118043823 118045038 118049755
JRE109013498 109015998
QSU111991104
QLO115953108 115954239 115986604
TWL119991890 119995245 120013756
VVI100258115 100267521
VRI117920785 117927357
SLY543710 778279
SPEN107002529 107009907
SOT102577786(SPP2)
CANN107854535 107874940
NTA107767908(NtSPP1) 107819363(NtSPP2) 107828694 107830739
NSY104221533 104224388
NTO104101716 104121433
NAU109214337
INI109181503
ITR116005516
SIND105161697 105173967
OEU111366032 111412291
EGT105950000
SSPL121744913 121789011 121796338 121800137
HAN110880252 110904344
ECAD122581364 122602998
LSV111899801 111916621
CCAV112516457 112519430
DCR108206327 108216063 108223892
CSIN114260045
BVG104893197 104907189
SOE110784542 110798139
CQI110688864 110724572 110737398 110739865
NNU104605199
MING122061646
TSS122668118
PSOM113300334 113306837 113307747 113310687 113314020 113322703 113337446
NCOL116246271 116247137 116255103
OSA4325448 4328274 4337789
DOSAOs01t0376700-01(Os01g0376700) Os02t0143100-01(Os02g0143100)
OBR102701032 102708121 102714559
BDI100829936 100832864
ATS109757507 109762595
TDC119298726 119306958 119324805 119364741
TAES100037524 123111541 123180419 123191080 542869 543056
SBI8056063 8069481 8075958
ZMA541868 542661
SITA101753890 101754411 101774746
SVS117845004 117848794 117857342
PVIR120664227 120667349 120676286 120697411 120709450
PHAI112886207 112886848 112894014
PDA103707401 103719698
EGU105042413 105059936
MUS103971455 103993085
DCT110107244
PEQ110028814
AOF109820022 109828864
ATR18421607
SMOSELMODRAFT_121516 SELMODRAFT_182236 SELMODRAFT_236983 SELMODRAFT_402942 SELMODRAFT_410141
PPP112275244 112276303 112287275 112291548
MNGMNEG_4690
CSLCOCSUDRAFT_15248
CVRCHLNCDRAFT_53400
APROF751_1470
CPVcgd6_2840
CHOChro.60329
TGOTGME49_217850
GTTGUITHDRAFT_114736 GUITHDRAFT_115146
VSHBSZ05_23475
VTAB0839
VCCFAZ90_09365
SYKKDN34_13250
SAVIJYB87_15190
METLU737_05515
MBUREQU24_03050
MESLKKZ03_07360
TCXTcr_1795
HTREPV75_09715
HMARHVMH_0657
THIOAYJ59_03305 AYJ59_04275
THIGFE785_04525
TXAHQN79_07955
TZOTHMIRHAT_22250
TLOJ9253_00765
TANIJ8380_02215
NHLNhal_2558
NWANwat_2809
NWRE3U44_09995
ALVAlvin_0251
TVIThivi_1157
THIPN838_02215
THIMKFB96_10545
TBOGLT988_06540
HAZA9404_10340
GAIIMCC3135_06960
GHLGM160_01010
TTCFOKN1_2844
HOLHORIV_03720
RACRA876_16680
SIMPC6571_13440
TINTint_2684
THITHI_3226
SNIVSFSGTM_16980
DEUDBW_2298(mfppA)
DWDDSCW_55820
LABRCHH27_00885
LABTFIU93_26000(mfppA)
LAGGB0E33_03125
PBRPB2503_13414
MGMMmc1_2291 Mmc1_3515
MAESGa0123461_1717
BACOOXB_3530
LYGC1N55_13945
PSYHD0S48_01690
ASOCCB4_03629(mfppA)
KYRCVV65_03215
SSILSOLI23_18030
PLNPlano_0410
PRTAUC31_07610
PLLI858_005325
PANABBH88_00325
PDGBCM40_13665
PHCBBI08_15055
PMARB0X71_02580
PPLABBI15_14410
PFAEAJGP001_02575
PLXCW734_03755
PMATBBI11_03505
PDECH1Q58_02650
SPORSporoP33_05635
SPOPSporoP37_06125
RSTATY39_08965
PLAYDNR44_000870
PTHPTH_0618(Cof)
STHRBXT84_11770
SYNslr0953
SYZMYO_118620
SYYSYNGTS_1845(slr0953)
SYTSYNGTI_1845(slr0953)
SYSSYNPCCN_1844(slr0953)
SYQSYNPCCP_1844(slr0953)
SYJD082_32810
SYOC7I86_09605
SYPSYNPCC7002_A0887
SYVAWQ23_04595
SYLAWQ21_05190
DSLDacsa_0649
CMPCha6605_0297
AMRAM1_2884(spp)
LENLEP3755_41890
LETO77CONTIG1_04515(mfppA)
LBOLBWT_43300
KOVK9N68_23600
LSCKIK02_09085
LSKJ5X98_14540
THEUHPC62_07905
GLPGlo7428_0776
CHONNIES4102_31360
HAOPCC7418_1364
ENNFRE64_03350
CYTcce_1207(sps)
CYCPCC7424_4476
CYJCyan7822_2392
CYNCyan7425_4592
OXYHCG48_05550
MVAGD0A34_19850
MICMic7113_1367
GEIGEI7407_1610
OACOscil6304_5556
ONIOsc7112_3132
MPROBJP34_15325
CEPCri9333_1967
GVIgll3839
GLJGKIL_4106
GMLISF26_15630
ANAall0376
NPUNpun_F3066 Npun_R3569
NOSNos7107_4134
NOPNos7524_0250
NONNOS3756_02770
NFLCOO91_04164
NOECLI64_22925
NSHGXM_02276 GXM_09606
NEDHUN01_11595 HUN01_32555
AVAAva_2821
NAZAazo_2470
ANBANA_C10157 ANA_C12946
ACYAnacy_4941
AWAAA650_15310 AA650_21190
ANNEH233_21550
CSGCylst_0594
RSINB6N60_02261
CALOCal7507_2549
CALTCal6303_0610
CALHIJ00_04815
RIVRiv7116_6091
FISFIS3754_12960
DOUBMF77_02685(mfppA_1) BMF77_04436(mfppA_3)
DFSHGD76_01200 HGD76_03985
CCURIAR63_05280
AFLOHEQ12_12270
TOQHCG51_27175
NCNBZZ01_32000
CTHEChro_0680
PLPPle7327_3241
SCSSta7437_2821
STANSTA3757_07510
LUOHHL09_01620
RULUC8_59070(mfppA)
AHELQ31a_06240(mfppA)
BVOPan97_31840(mfppA)
RLCK227x_26760(mfppA)
FMRFuma_03288(mfppA)
PLONPla110_03550(mfppA)
MCADPan265_24600(mfppA)
SSMSpirs_0902
SLRL21SP2_2635
POBLPB03_05965
PRNBW723_17540
AHZAPS56_07830
SEONBWZ22_10920
TAJC1A40_11725
MARFCJ739_417
 » show all
Reference
1  [PMID:4290548]
  Authors
Hawker JS, Hatch MD.
  Title
A specific sucrose phosphatase from plant tissues.
  Journal
Biochem J 99:102-7 (1966)
DOI:10.1042/bj0990102
Reference
2  [PMID:11050182]
  Authors
Lunn JE, Ashton AR, Hatch MD, Heldt HW
  Title
Purification, molecular cloning, and sequence analysis of sucrose-6F-phosphate phosphohydrolase from plants.
  Journal
Proc Natl Acad Sci U S A 97:12914-9 (2000)
DOI:10.1073/pnas.230430197
  Sequence
[zma:541868] [osa:4328274] [ath:AT2G35840 AT3G54270]
Reference
3  [PMID:12753969]
  Authors
Lunn JE, MacRae E
  Title
New complexities in the synthesis of sucrose.
  Journal
Curr Opin Plant Biol 6:208-14 (2003)
DOI:10.1016/S1369-5266(03)00033-5
Reference
4  [PMID:15937230]
  Authors
Fieulaine S, Lunn JE, Borel F, Ferrer JL
  Title
The structure of a cyanobacterial sucrose-phosphatase reveals the sugar tongs that release free sucrose in the cell.
  Journal
Plant Cell 17:2049-58 (2005)
DOI:10.1105/tpc.105.031229
Other DBs
ExplorEnz - The Enzyme Database: 3.1.3.24
IUBMB Enzyme Nomenclature: 3.1.3.24
ExPASy - ENZYME nomenclature database: 3.1.3.24
BRENDA, the Enzyme Database: 3.1.3.24
CAS: 9059-33-0

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