KEGG ENZYME: 3.1.3.24

ENZYME: 3.1.3.24

Entry

EC 3.1.3.24                 Enzyme

Name

sucrose-phosphate phosphatase;
sucrose 6-phosphate hydrolase;
sucrose-phosphate hydrolase;
sucrose-phosphate phosphohydrolase;
sucrose-6-phosphatase;
sucrose phosphatase;
sucrose-6-phosphate phosphatase;
SPP

Class

Hydrolases;
Acting on ester bonds;
Phosphoric-monoester hydrolases

Sysname

sucrose-6F-phosphate phosphohydrolase

Reaction(IUBMB)

sucrose 6F-phosphate + H2O = sucrose + phosphate [RN:R00805 R06211]

Reaction(KEGG)

R00805 R06211(G)

Substrate

sucrose 6F-phosphate [CPD:C02591];
H2O [CPD:C00001]

Product

sucrose [CPD:C00089];
phosphate [CPD:C00009]

Comment

Requires Mg2+ for maximal activity [2]. This is the final step in the sucrose-biosynthesis pathway. The enzyme is highly specific for sucrose 6-phosphate, with fructose 6-phosphate unable to act as a substrate [2]. Belongs in the haloacid dehydrogenase (HAD) superfamily. The F of sucrose 6F-phosphate is used to indicate that the fructose residue of sucrose carries the substituent.

History

EC 3.1.3.24 created 1972, modified 2008

Pathway

ec00500

Starch and sucrose metabolism

ec01100

Metabolic pathways

ec01110

Biosynthesis of secondary metabolites

Orthology

K07024

sucrose-6-phosphatase

Genes

ATH:	AT1G51420(SPP1) AT2G35840 AT3G52340(SPP2) AT3G54270

ALY:	9313927 9314033 9315646 9330377

CRB:	17885437 17885460 17888311 17897904

CSAT:

104711347 104711786 104712007 104712793 104713932 104742656 104758452 104778051 104781077 104781293 104781996 104785950 104791485 104791699 104792218 104792360

EUS:	EUTSA_v10010361mg EUTSA_v10010402mg EUTSA_v10011514mg EUTSA_v10016712mg EUTSA_v10023476mg

BRP:	103832861 103841339 103857590 103863242 103863471 103865486 103868568

BNA:	106366954 106388145 106390094 106391426 106394386 106411802 106412074 106417948 106430593 106430595 106431371 106437864 106439027 106449288 106449368 125605301

BOE:	106309682 106328025 106328735 106340346 106341229 106342543

RSZ:	108819311 108847325 108849559 108853936 108857233 108859954

THJ:	104808403 104811340

CPAP:

110816808

CIT:

102613091

CIC:	CICLE_v10011822mg CICLE_v10015425mg

PVY:	116106042 116129816

MINC:

123192306 123216387

TCC:	18586901 18598461

GRA:	105766586 105770662

GHI:	107893582 107899194 107904387 121217938

GAB:	108453353 108460850

HSYR:

120180765 120214535

DZI:	111293650 111310424 111311629

EGR:	104446642 104454069

RARG:

115726668 115749732

GMX:	100796915 100800397

GSJ:	114372119 114403740

PVU:	137830389 137830719

VRA:	106769690 106770962

VAR:	108318780 108326002

VUN:	114190059 114192146

VUM:	124843030 124844261

CCAJ:

109794427 109813367

APRC:

113871066 113873679

MTR:	11423632 25483624

TPRA:

123909740 123913101

CAM:	101495120 101505023

PSAT:

127091485 127091527

VVO:	131595882 131636082 131644727

LJA:	130720105 130723434

ADU:	107470592 107476034

AIP:	107623437 107626301

AHF:	112716015 112728709 112757332 112784279

LANG:

109325807 109325808 109336456

PCIN:

129293423 129321888

QSA:	O6P43_004844 O6P43_005753

FVE:	101300366 101312086

AANS:

126800183 126800198 126801603

RCN:	112182942 112192942

PPER:

18770457 18775718

PMUM:

103336602 103339575

PAVI:

110749204 110758071

PDUL:

117628203 117635052

MDM:	103408838 103418485 103430254 103454193

MSYL:

126582225 126582250 126594376 126600849

PXB:	103940216 103946089 103946090 103952711

PCOX:

137712834 137744751 137748190 137748245

ZJU:	107412966 107433599

MNT:	21389873 21403135

CSAV:

115700530 115705752

CSV:	101205644 101212615

CMO:	103486711 103489356

BHJ:	120081542 120091771

MCHA:

111018765 111019350

CMAX:

111467778 111498604

CMOS:

111441900 111449724

CPEP:

111800682 111801786

RCU:

8259817

MEAN:

126678221

JCU:

105635774

HBR:	110653619 110655835

MESC:

110621424 110622142 110625179

POP:	7469925 7479489 7490873

PEU:	105131608 105138205 105141578

PALZ:

118043823 118045038 118049755

PNZ:	133677701 133689680 133704663

JRE:	109013498 109015998

CILL:

122279804 122293915

CAVE:

132167551 132191517

AGLU:

133874128 133880678

QSU:	111991104 112026970

QLO:	115953108 115954239 115986604

TWL:	119991890 119995245 120013756

VVI:	100258115 100267521

VRI:	117920785 117927357

SLY:	543710 778279

SPEN:

107002529 107009907

SOT:	102577786(SPP2)

SSTN:

125852589 125864937

SDUL:

129876379 129887752

CANN:

107854535 107874940

LBB:	132607251 132625962

NTA:	107767908(NtSPP1) 107819363(NtSPP2) 107828694 107830739

NSY:	104221533 104224388

NTO:	104101716 104121433

NAU:

109214337

INI:

109181503

ITR:

116005516

SIND:

105161697 105173967

OEU:	111366032 111412291

EGT:

105950000

SSPL:

121744913 121789011 121796338 121800137

SMIL:

130997120 131026280

SHIS:

125190354 125194220

APAN:

127252069

HAN:	110880252 110904344

ECAD:

122581364 122602998

LSV:	111899801 111916621

CCAV:

112516457 112519430

DCR:	108206327 108216063 108223892

CSIN:

114260045

RVL:	131301742 131334828 131334835

AEW:	130757576 130788925

DLT:	127801700 127805500

BVG:	104893197 104907189

SOE:	110784542 110798139

CQI:	110688864 110724572 110737398 110739865

ATRI:

130797333 130800491 130804474

MOF:	131147260 131147261 131166300

NNU:

104605199

MING:

122061646

TSS:

122668118

PSOM:

113300334 113306837 113307747 113310687 113314020 113322703 113337446

OSA:	4325448(OsJ_01840) 4328274(OsSPP2) 4337789

DOSA:

Os01g0376700 Os02g0143100 Os05g0144900

OBR:	102701032 102708121 102714559

OGL:	127763520 127773642 127780661

BDI:	100829936 100832864

ATS:	109757507 109762595

TDC:	119298726 119306958 119324805 119364741

TAES:

100037524 123111541 123180419 123191080 542869 543056

TUA:	125506719 125549218

LPER:

127311344 127321979 127347526

LRD:	124664359 124677881 124678575 124707953

SBI:	8056063 8069481 8075958

ZMA:	541868 542661

MFLO:

136512076 136512077 136513673 136515356

SITA:

101753890 101754411 101774746

SVS:	117845004 117848794 117857342

PVIR:

120664227 120667349 120676286 120697411 120709450

PHAI:

112886207 112886848 112894014

PAUA:

133884406 133901573 133912282

PDA:	103707401 103719698

EGU:	105042413 105059936

MUS:	103993085 135626315

ZOF:	121970521 121970794 121975591 121976813 122036850 122044937

DCT:

110107244

PEQ:

110028814

AOF:	109820022 109828864

MSIN:

131234040

ACAK:

137936957 137940297

NCOL:

116246271 116247137 116255103

ATR:

18421607

CJF:	131036920 131059714

SMO:	SELMODRAFT_121516 SELMODRAFT_182236 SELMODRAFT_236983 SELMODRAFT_402942 SELMODRAFT_410141

PPP:	112275244 112276303 112287275 112291548

MNG:

MNEG_4690

CSL:	COCSUDRAFT_15248

CVR:	CHLNCDRAFT_53400

APRO:

F751_1470

CPV:

cgd6_2840

CHO:	Chro.60329

GTT:	GUITHDRAFT_114736 GUITHDRAFT_115146

VSH:	BSZ05_23475

VTA:

B0839

VCC:	FAZ90_09365

VLE:	ISX51_12885

VSY:	K08M4_11730(mfppA)

VIH:	AB0763_17020

SAVI:

JYB87_15190

MSZE:

MSZNOR_0280

MECH:

Q9L42_008145

TCX:

Tcr_1795

HTR:	EPV75_09715

HMAR:

HVMH_0657

THIO:

AYJ59_03305 AYJ59_04275

MMAF:

GCM100_03320

MTHA:

VSX76_08180

THIG:

FE785_04525

TXA:	HQN79_07955

TZO:	THMIRHAT_22250

TLR:	Thiosp_04812(mfppA)

TFRI:

Thiofri_04869(mfppA)

TWG:	Thiowin_04767(mfppA)

HOL:	HORIV_03720

SIMP:

C6571_13440

TIN:

Tint_2684

THI:

THI_3226

LABR:

CHH27_00885

LABT:

FIU93_26000(mfppA)

LAGG:

B0E33_03125

RPOP:

K1718_19985

PBR:	PB2503_13414

DHG:	EYB58_08160

CALG:

SH580_14575

LUO:	HHL09_01620

RUL:	UC8_59070(mfppA)

RUV:	EC9_36480(mfppA)

RCF:	Poly24_35940(mfppA)

AHEL:

Q31a_06240(mfppA)

BVO:	Pan97_31840(mfppA)

BREM:

PSR63_22510 PSR63_22525

RLC:	K227x_26760(mfppA)

SMAM:

Mal15_22870(mfppA)

SNEP:

Enr13x_55520(mfppA)

BGOK:

Pr1d_01220(mfppA_1) Pr1d_27920(mfppA_2)

FMR:	Fuma_03288(mfppA)

PLON:

Pla110_03550(mfppA)

ACAF:

CA12_04640(mfppA)

SVP:	Pan189_19430(mfppA)

TPOL:

Mal48_04430(mfppA)

CHYA:

V22_27410(mfppA)

MCAD:

Pan265_24600(mfppA)

CHIM:

CK934_02800

NDF:	KRR40_19765

POB:	LPB03_05965

PRN:	BW723_17540

AHZ:	APS56_07830

SEON:

BWZ22_10920

TAJ:	C1A40_11725

MARF:

CJ739_417

TVX:	QBE54_00345

ATHO:

M15_20420

BACO:

OXB_3530

FEC:	QNH15_14835

PSYH:

D0S48_01690

ACHP:

QR721_11900

ASOC:

CB4_03629(mfppA)

AUD:	PO771_15090

ANEU:

PP175_06575

KYR:	CVV65_03215

PLN:	Plano_0410

PRT:	AUC31_07610

PLL:	I858_005325

PPLA:

BBI15_14410

PLX:	CW734_03755

PMAT:

BBI11_03505

PDEC:

H1Q58_02650

PLAY:

DNR44_000870

PLIQ:

QWY22_02720

PSHE:

QWY16_02610

PSHX:

QWY21_02650

SPOR:

SporoP33_05635

SPOP:

SporoP37_06125

SPOO:

J3U78_16335

STRB:

QWT68_15265

SJT:	PGH26_12790

RST:	ATY39_08965

PTH:	PTH_0618(Cof)

STHR:

BXT84_11770

SYN:

slr0953

SYZ:	MYO_118620

SYY:	SYNGTS_1845(slr0953)

SYT:	SYNGTI_1845(slr0953)

SYS:	SYNPCCN_1844(slr0953)

SYQ:	SYNPCCP_1844(slr0953)

SYJ:	D082_32810

SYO:	C7I86_09605

SYNH:

HTZ78_13255

SYNS:

OLK001_27380

DSL:	Dacsa_0649

CMP:	Cha6605_0297

CYN:	Cyan7425_4592

CEP:	Cri9333_1967

AMR:	AM1_2884(spp)

ACAM:

HRE53_11465

LEN:	LEP3755_41890

LET:	O77CONTIG1_04515(mfppA)

LBO:	LBWT_43300

KOV:	K9N68_23600

LSC:	KIK02_09085

LSK:	J5X98_14540

SFRI:

RBJ76_12170

THEU:

HPC62_07905

TOG:	HNI00_18905

TSIN:

OXH18_17335

GLP:	Glo7428_0776

CHON:

NIES4102_31360

GDU:	P0S91_15890

SYP:	SYNPCC7002_A0887

SYV:	AWQ23_04595

SYL:	AWQ21_05190

PIP:	FEK30_08545

HAO:	PCC7418_1364

ENN:	FRE64_03350

CYT:	cce_1207(sps)

CYC:	PCC7424_4476

CYJ:	Cyan7822_2392

MVAG:

D0A34_19850

OXY:	HCG48_05550

OAC:	Oscil6304_5556

ONI:	Osc7112_3132

MPRO:

BJP34_15325

MIC:	Mic7113_1367

GEI:	GEI7407_1610

GVI:

gll3839

GLJ:

GKIL_4106

GML:	ISF26_15630

ANA:

all0376

NPU:	Npun_F3066 Npun_R3569

NOS:	Nos7107_4134

NOP:	Nos7524_0250

NON:	NOS3756_02770

NFL:	COO91_04164

NOE:	CLI64_22925

NSH:	GXM_02276 GXM_09606

NED:	HUN01_11595 HUN01_32555

NPZ:	ACX27_02245

NLK:	NIES25_46760 NIES25_66990

NCW:	NIES2107_39090

NCF:	ANSO36C_61560

NOST:

GJB62_01460 GJB62_23575

NOSU:

JYQ62_11820

NOSQ:

PQG02_14460

AVA:

Ava_2821

NAZ:

Aazo_2470

ANB:	ANA_C10157 ANA_C12946

ACY:	Anacy_4941

AWA:	AA650_15310 AA650_21190

ANN:	EH233_21550

CSG:	Cylst_0594

RSIN:

B6N60_02261

HBQ:	QI031_16870

NSPH:

BDGGKGIB_00072(mfppA)

AEE:	IM676_17485

CALO:

Cal7507_2549

CALT:

Cal6303_0610

CALH:

IJ00_04815

CALN:

NIES2098_71860

CALS:

NIES3974_41930

RIV:	Riv7116_6091

MDP:	NIES3275_14850

FIS:	FIS3754_12960

DOU:	BMF77_02685(mfppA_1) BMF77_04436(mfppA_3)

DFS:	HGD76_01200 HGD76_03985

DHT:	NG743_05705 NG743_22395

DCM:	NIES806_21240 NIES806_31060

DOT:	EZY12_21705

DOZ:	HEP80_07580

DOC:	HEQ26_02930

CCUR:

IAR63_05280

CRK:	L3I90_06455

AFLO:

HEQ12_12270

STOQ:

K2F26_12360

SKV:	NIES73_26500

OCF:	WJM97_01120

TOQ:	HCG51_27175

TTQ:	NIES37_29420

ALAX:

NIES50_57190

SCYT:

SAMD_50970

SCYS:

NIES4073_44870

BSEN:

DP114_16075

BOX:	DP113_16010

NCN:	BZZ01_32000

CTHE:

Chro_0680

PLP:	Ple7327_3241

SCS:	Sta7437_2821

STAN:

STA3757_07510

» show all

Reference

1 [PMID:4290548]

Authors

Hawker JS, Hatch MD.

Title

A specific sucrose phosphatase from plant tissues.

Journal

Biochem J 99:102-7 (1966)
DOI:10.1042/bj0990102

Reference

2 [PMID:11050182]

Authors

Lunn JE, Ashton AR, Hatch MD, Heldt HW

Title

Purification, molecular cloning, and sequence analysis of sucrose-6F-phosphate phosphohydrolase from plants.

Journal

Proc Natl Acad Sci U S A 97:12914-9 (2000)
DOI:10.1073/pnas.230430197

Sequence

[zma:541868] [osa:4328274] [ath:AT2G35840 AT3G54270]

Reference

3 [PMID:12753969]

Authors

Lunn JE, MacRae E

Title

New complexities in the synthesis of sucrose.

Journal

Curr Opin Plant Biol 6:208-14 (2003)
DOI:10.1016/S1369-5266(03)00033-5

Reference

4 [PMID:15937230]

Authors

Fieulaine S, Lunn JE, Borel F, Ferrer JL

Title

The structure of a cyanobacterial sucrose-phosphatase reveals the sugar tongs that release free sucrose in the cell.

Journal

Plant Cell 17:2049-58 (2005)
DOI:10.1105/tpc.105.031229

Other DBs

ExplorEnz - The Enzyme Database:

3.1.3.24

IUBMB Enzyme Nomenclature:

3.1.3.24

ExPASy - ENZYME nomenclature database:

3.1.3.24

BRENDA, the Enzyme Database:

3.1.3.24

CAS:

9059-33-0

DBGET integrated database retrieval system