Entry |
|
Name |
sucrose-phosphate phosphatase;
sucrose 6-phosphate hydrolase;
sucrose-phosphate hydrolase;
sucrose-phosphate phosphohydrolase;
sucrose-6-phosphatase;
sucrose phosphatase;
sucrose-6-phosphate phosphatase;
SPP
|
Class |
Hydrolases;
Acting on ester bonds;
Phosphoric-monoester hydrolases
|
Sysname |
sucrose-6F-phosphate phosphohydrolase
|
Reaction(IUBMB) |
sucrose 6F-phosphate + H2O = sucrose + phosphate [RN: R00805 R06211]
|
Reaction(KEGG) |
|
Substrate |
|
Product |
|
Comment |
Requires Mg2+ for maximal activity [2]. This is the final step in the sucrose-biosynthesis pathway. The enzyme is highly specific for sucrose 6-phosphate, with fructose 6-phosphate unable to act as a substrate [2]. Belongs in the haloacid dehydrogenase (HAD) superfamily. The F of sucrose 6F-phosphate is used to indicate that the fructose residue of sucrose carries the substituent.
|
History |
EC 3.1.3.24 created 1972, modified 2008
|
Pathway |
ec00500 | Starch and sucrose metabolism |
ec01110 | Biosynthesis of secondary metabolites |
|
Orthology |
|
Genes |
» show all
|
Reference |
|
Authors |
Hawker JS, Hatch MD. |
Title |
A specific sucrose phosphatase from plant tissues. |
Journal |
|
Reference |
|
Authors |
Lunn JE, Ashton AR, Hatch MD, Heldt HW |
Title |
Purification, molecular cloning, and sequence analysis of sucrose-6F-phosphate phosphohydrolase from plants. |
Journal |
|
Sequence |
|
Reference |
|
Authors |
Lunn JE, MacRae E |
Title |
New complexities in the synthesis of sucrose. |
Journal |
|
Reference |
|
Authors |
Fieulaine S, Lunn JE, Borel F, Ferrer JL |
Title |
The structure of a cyanobacterial sucrose-phosphatase reveals the sugar tongs that release free sucrose in the cell. |
Journal |
|
Other DBs |
ExplorEnz - The Enzyme Database: | 3.1.3.24 |
ExPASy - ENZYME nomenclature database: | 3.1.3.24 |
|