KEGG   ENZYME: 3.1.3.26
Entry
EC 3.1.3.26                 Enzyme                                 
Name
4-phytase;
6-phytase (name based on 1L-numbering system and not 1D-numbering);
phytase;
phytate 6-phosphatase;
myo-inositol-hexakisphosphate 6-phosphohydrolase (name based on 1L-numbering system and not 1D-numbering)
Class
Hydrolases;
Acting on ester bonds;
Phosphoric-monoester hydrolases
Sysname
myo-inositol-hexakisphosphate 4-phosphohydrolase
Reaction(IUBMB)
myo-inositol hexakisphosphate + H2O = 1D-myo-inositol 1,2,3,5,6-pentakisphosphate + phosphate [RN:R03372]
Reaction(KEGG)
R03372
Substrate
myo-inositol hexakisphosphate [CPD:C01204];
H2O [CPD:C00001]
Product
1D-myo-inositol 1,2,3,5,6-pentakisphosphate [CPD:C04579];
phosphate [CPD:C00009]
History
EC 3.1.3.26 created 1972, modified 1976, modified 2002
Pathway
ec00562  Inositol phosphate metabolism
ec01100  Metabolic pathways
Orthology
K01093  4-phytase / acid phosphatase
Genes
ECOb0980(appA)
ECJJW0963(appA)
ECDECDH10B_1050(appA)
EBWBWG_0832(appA)
ECOKECMDS42_0832(appA)
ECEZ1397(appA)
ECSECs_1136(appA)
ECFECH74115_1216(appA)
ETWECSP_1149(appA)
ELXCDCO157_1101
EOIECO111_1091(appA)
EOJECO26_1535(appA)
EOHECO103_1025(appA)
ECOOECRM13514_1157(appA)
ECOHECRM13516_1086(appA)
ESLO3K_16440
ESOO3O_08855
ESMO3M_16415
ECKEC55989_1088(appA)
ECGE2348C_0965(appA)
EOKG2583_1215(appA)
ELRECO55CA74_05935
ELHETEC_1049
ECWEcE24377A_1096(appA)
EUNUMNK88_1135
ECPECP_0985
ENAECNA114_1060(appA)
ECOSEC958_1185(appA)
ECVAPECO1_84(appA)
ECOAAPECO78_08890
ECXEcHS_A1089(appA)
ECMEcSMS35_2136(appA)
ECYECSE_1042
ECRECIAI1_1021(appA)
ECQECED1_1064(appA)
EUMECUMN_1170(appA)
ECTECIAI39_2166(appA)
EOCCE10_1008(appA)
EBRECB_00983(appA)
EBLECD_00983(appA)
EBEB21_00990(appA)
EBDECBD_2614
ECIUTI89_C1049(appA)
EIHECOK1_1042(appA)
ECZECS88_1002(appA)
ECCc1121(appA)
ELOEC042_1065(appA)
ELNNRG857_04465
ESEECSF_0894
ECLEcolC_2616
EKOEKO11_2850
EKFKO11_17825(appA)
EABECABU_c10140(appA)
EDHEcDH1_2663
EDJECDH1ME8569_0932(appA)
ELUUM146_12675
ELWECW_m1091(appA)
ELLWFL_05315(appA)
ELCi14_1025(appA)
ELDi02_1025(appA)
ELPP12B_c0967(appA)
ELFLF82_0100(appA)
ECOLLY180_05140
ECOIECOPMV1_01011(appA_1)
ECOJP423_05380
EFEEFER_3043
EALEAKF1_ch0429c(appA)
EMAC1192_07320
ESZFEM44_19790
SFLSF0982(appA)
SFXS1048(appA)
SFVSFV_0989(appA)
SFESFxv_1064(appA)
SFNSFy_1341
SFSSFyv_1383
SFTNCTC1_01020(appA_1)
SSNSSON_0987(appA)
SBOSBO_2250(appA)
SBCSbBS512_E2335(appA)
SDYSDY_0956(appA)
SDZAsd1617_01201
SHQA0259_09025
ENRH650_02130
ESAESA_02095
CSKES15_2251(appA)
CSZCSSP291_09965
CSJCSK29544_03387
CSIP262_03255
CUIAFK65_08545
CTUCTU_18700(appA)
KPNKPN_00628
KPUKP1_1578
KPMKPHS_14650
KPPA79E_3612
KPHKPNIH24_21485
KPZKPNIH27_06790
KPVKPNIH29_07485
KPWKPNIH30_07515
KPYKPNIH31_07390
KPGKPNIH32_07620
KPCKPNIH10_07305
KPQKPR0928_07215
KPTVK055_1906(phyK)
KPOKPN2242_01675 KPN2242_06005
KPRKPR_3951
KPJN559_3698
KPID364_03295
KPAKPNJ1_03953
KPSKPNJ2_03943
KPXPMK1_02960(agp_1)
KPBFH42_24175
KPNEKU54_019140
KPNULI86_18965
KPNKBN49_1685 BN49_4737(appA)
KVAKvar_3740
KPEKPK_3948
KPKA593_17605
KVDKR75_15065
KOXKOX_14030
KOEA225_1624
KOYJ415_23510
KOMHR38_12765
KOKKONIH1_07970
KQUAVR78_11805
EAEEAE_02525
EARCCG33480
KQVB8P98_20555
KLLBJF97_08350
KLWDA718_20335
KARLGL98_18165
KGRJJJ10_20205
RORRORB6_11940
RONTE10_08950
RPLNB1209_19645
RAODSD31_18475
RTGNCTC13098_04907(agp_2)
CWECO701_07465
CFQC2U38_04960
CAFAL524_16675
CIRC2U53_20695
HDEHDEF_2244(appA)
KSAC813_02725
KRDA3780_12010
KPSEIP581_11955
BUFD8682_18890
IZHFEM41_23385
PSHISAMEA2665130_1541(appA_4)
EBUCUC76_08260
YPEYPO1648
YPKy1810(appA)
YPHYPC_1753
YPAYPA_1875
YPNYPN_1982
YPMYP_1778(appA)
YPPYPDSF_1799
YPGYpAngola_A2841(appA)
YPZYPZ3_2046
YPTA1122_17635
YPDYPD4_2087
YPXYPD8_2084
YPWCH59_189(appA)
YPJCH55_223(appA)
YPVBZ15_1903(appA)
YPLCH46_3477(appA)
YPSYPTB2421
YPOBZ17_30(appA)
YPIYpsIP31758_1622(appA)
YPYYPK_1730
YPBYPTS_2503
YPQDJ40_4145(appA)
YPUBZ21_1712(appA)
YPRBZ20_3780(appA)
YPCBZ23_1998(appA)
YPFBZ19_1789(appA)
YENYE2600
YEPYE105_C1662
YEYY11_14891
YELLC20_02112
YEWCH47_1942(appA)
YETCH48_3266(appA)
YEFFORC2_2576
YEEYE5303_23821
YSIBF17_21295
YALAT01_51(appA)
YFRAW19_831(appA)
YINCH53_3517(appA)
YKRCH54_831
YROCH64_183(appA)
YAKACZ76_01245
YMADA391_08650
YHID5F51_10995
YCAF0T03_13360
YMOHRD69_13485
SMAFD781_3671
SRZAXX16_1414
SERASer39006_002070
SERQCWC46_02070
SERMCLM71_23710
SOFNCTC11214_01745(appA_1)
SRHZFO014_10010
GQUAWC35_02855
RBADH2866_12100
ECAECA4198
PATREV46_20920
PATOGZ59_42580
PCTPC1_3998
PCCPCC21_039770
PWAPecwa_4189
PPARA8F97_20560
PECW5S_4347
PWSA7983_06065
PPOABJK05_14960
PBRAB5S52_01235
PPUJE2566_20310
PARII2D83_01305
PAQUDMB82_0019175
PVZOA04_42630
PPAVLOZ86_02330
DDDDda3937_01138
DZEDd1591_4136
DDCDd586_4105
DZCW909_19900
DSOA4U42_08550
CEDLH89_12890
DFNCVE23_22000
DDQDDI_4181
DAQDAQ1742_00052
DICDpoa569_000047
DDADd703_3938
LBQCKQ53_08705
LPOPI6N93_12585
EBIEbC_09720(appa)
EGEEM595_0941
EPECI789_13695
ERWIGN242_16350 GN242_16370
PAMPANA_0959(agp)
PLFPANA5342_3343(phyK)
PAJPAJ_0285(agp)
PAQPAGR_g3246
PVAPvag_0342(phyK)
PAGGAL522_08675
PAOPat9b_0907
PANTPSNIH1_09405
PAGCBEE12_11405
PSTWDSJ_05650
PEYEE896_14885
PDISD8B20_04380 D8B20_04945
PERLAC65_03650
TPTYNCTC11468_02898(appA)
EICNT01EI_1443
ETRETAE_1316
ETDETAF_1224
ETEETEE_3291(appA)
ETCETAC_06220
EDWQY76_13330
EDLAAZ33_06825
EHOA9798_10215
HAVAT03_09325
HPARAL518_16440
OPODSM2777_09415
XCCXCC0760(appA)
XCBXC_3473
XCAxcc-b100_3594
XCPXCR_0938
XCVXCV0590(appA) XCV0864(appA) XCV4225
XAXXACM_0548(appA) XACM_0808 XACM_4001
XACXAC0557(appA) XAC0812(appA) XAC4132(appA)
XCIXCAW_00167(appA) XCAW_03768(appA)
XCTJ151_00678 J151_00938 J151_04311
XCJJ158_00675 J158_00935 J158_04264
XCUJ159_00675 J159_00935 J159_04260
XCNJ169_00674 J169_00934 J169_04308
XCWJ162_00674 J162_00934 J162_04266
XCRJ163_00674 J163_00934 J163_04260
XCMJ164_00674 J164_00934 J164_04261
XCFJ172_00669 J172_00929 J172_04301
XFUXFF4834R_chr05530 XFF4834R_chr08180(appA) XFF4834R_chr40020
XAOXAC29_02840 XAC29_04140 XAC29_20810
XOMXOO3574(XOO3574)
XOOXOO3792(appA)
XOPPXO_04687
XOYAZ54_04960
XORXOC_0877
XOZBE73_19995
XALXALC_2788
XSASB85_06825 SB85_08885 SB85_15620
XTNFD63_15880 FD63_18170
XVEBJD12_17075
XPEBJD13_12650 BJD13_14080 BJD13_18375
XHRXJ27_11295
XGABI317_04905
XPHXppCFBP6546_07375(XppCFBP6546P_07375) XppCFBP6546_08950(XppCFBP6546P_08950) XppCFBP6546_13775(XppCFBP6546P_13775)
XVAC7V42_02915 C7V42_04510
XANAC801_02705 AC801_04200 AC801_20520
XARXB05_00730 XB05_20985
XHYFZ025_13610
XCZEBN15_03110
XTHG4Q83_01245 G4Q83_02555
XEUXSP_000818
XHDLMG31886_31450(appA_1) LMG31886_35170(appA_2)
DCSISN74_19960
DTLH8F01_03305
LRZBJI69_17270
LPYFIV34_11065
PSBPsyr_4500
PRXHRH33_09805 HRH33_09810
PSKU771_10000 U771_10005
PFZAV641_16965 AV641_16970
PLQAA042_16710 AA042_16715
PPSYAOC04_14235 AOC04_14240
PPSHG5J76_20705
PEZHWQ56_10970
PTAENCTC10697_03275(agp)
MMOBF6R98_16485
ZPLZBT109_1255
ATYA9R16_007405
CDIZCEDIAZO_01004(agp)
LHKLHK_03226
DEEHQN60_06560
PPNODA70_12870
PPNMLV28_17830
PRBX636_14000
PPULRO07_12025
PSPUNA29_08045
PAPISG18_25920
PVEUC34_03875
POXMB84_08330
PFGAB870_14950
PNRAT302_02035 AT302_12140
PFIBPI93_003430
OTKC6570_10225
OFOBRW83_1278(appA_1) BRW83_1307(appA_2)
BBAYA4V04_07650
DFIAXF13_09085
DPGDESPIGER_0144
LIPLI0436 LI0438
LIRLAW_00452
AVIAvi_0609
ARUIG6M88_09665
BAPIBBC0122_017370
AZCAZC_4319
CCRCC_0542
CCSCCNA_00576(oppA)
CSECseg_2456 Cseg_3136
CFHC1707_14850
CAUFCSW63_14990
ZMOZMO0061
ZMNZa10_1128
ZMMZmob_0756
ZMBZZ6_1138
ZMIZCP4_1165
ZMCA265_01156(appA)
ZMRA254_01155(appA)
NREBES08_21135 BES08_24235
NOVTQ38_024435 TQ38_025560
NORFA702_18675
SMAGAN936_11405
SMAZLH19_12560
SPHOC3E99_18720
STAXMC45_02080 MC45_11915
SNJA7E77_13750
SMYBJP26_19115
SPANAWL63_14190
SPLKAV944_00945 AV944_08690
SPHFDM480_08675 DM480_15510
SPAUDRN02_015065
GOXGOX1076 GOX1190
GOHB932_1054
GOYGLS_c11450(appA)
GALA0U94_13015
GTIFXF46_05795
GSPIGS75_07320
GFAMKW11_05760
GBCGbCGDNIH3_1410
GBSGbCGDNIH4_1410
KEUS101446_02698(appA)
KSCCD178_00707(appA)
APTAPA01_03230
APWAPA42C_03230
APFAPA03_03230
APUAPA07_03230
APGAPA12_03230
APQAPA22_03230
APXAPA26_03230
APZAPA32_03230
APKAPA386B_1808(appA)
ASZASN_1924(appA)
ASVWG31_01590
APOMCPF11_05710
ATOCIW82_02435
AASCA4S02_10975
ACETDS739_01710
AOYEOV40_001640
ACEKFLP30_10775
ABGAsbog_01039
NTND5366_04285
AZLAZL_b01070
AZMDM194_22125
AZZDEW08_01260
NAOY958_04115 Y958_13160 Y958_24860
NCBC0V82_17515
MHADB586_02085
MLLB1R94_26470
MAICMAIC_03690(appA)
MANYMANY_34820(appA)
ACAACP_1579
GMAAciX8_0270
GRWFTO74_19065
TALBFTW19_21545
ABASACPOL_3731
EDAGWR55_14565
PFERIRI77_10650 IRI77_15290 IRI77_16660 IRI77_16665
CPORBED41_01000
 » show all
Reference
1  [PMID:4310376]
  Authors
Johnson LF, Tate ME.
  Title
The structure of myo-inositol pentaphosphates.
  Journal
Ann N Y Acad Sci 165:526-32 (1969)
DOI:10.1111/j.1749-6632.1970.tb56420.x
Reference
2  [PMID:13921788]
  Authors
TOMLINSON RV, BALLOU CE.
  Title
Myoinositol polyphosphate intermediates in the dephosphorylation of phytic acid by phytase.
  Journal
Biochemistry 1:166-71 (1962)
DOI:10.1021/bi00907a025
Reference
3  [PMID:4349266]
  Authors
Lim PE, Tate ME.
  Title
The phytases. II. Properties of phytase fractions F 1  and F 2  from wheat bran and the myoinositol phosphates produced by fraction F 2 .
  Journal
Biochim Biophys Acta 302:316-28 (1973)
DOI:10.1016/0005-2744(73)90160-5
Reference
4
  Authors
Cosgrove, D.J.
  Title
Inositol Phosphates: Their Chemistry, Biochemistry, and Physiology, Elsevier, Amsterdam, 1980
Other DBs
ExplorEnz - The Enzyme Database: 3.1.3.26
IUBMB Enzyme Nomenclature: 3.1.3.26
ExPASy - ENZYME nomenclature database: 3.1.3.26
BRENDA, the Enzyme Database: 3.1.3.26
CAS: 9001-89-2

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