KEGG   ENZYME: 3.1.3.59Help
Entry
EC 3.1.3.59                 Enzyme                                 

Name
alkylacetylglycerophosphatase;
1-alkyl-2-lyso-sn-glycero-3-P:acetyl-CoA acetyltransferase;
alkylacetylglycerophosphate phosphatase
Class
Hydrolases;
Acting on ester bonds;
Phosphoric-monoester hydrolases
BRITE hierarchy
Sysname
1-alkyl-2-acetyl-sn-glycero-3-phosphate phosphohydrolase
Reaction(IUBMB)
1-alkyl-2-acetyl-sn-glycero-3-phosphate + H2O = 1-alkyl-2-acetyl-sn-glycerol + phosphate [RN:R03454]
Reaction(KEGG)
Substrate
1-alkyl-2-acetyl-sn-glycero-3-phosphate;
H2O [CPD:C00001]
Product
1-alkyl-2-acetyl-sn-glycerol [CPD:C03820];
phosphate [CPD:C00009]
Comment
Involved in the biosynthesis of thrombocyte activating factor in animal tissues.
History
EC 3.1.3.59 created 1989
Pathway
ec00565  Ether lipid metabolism
ec01100  Metabolic pathways
Reference
1  [PMID:3007498]
  Authors
Lee TC, Malone B, Snyder F.
  Title
A new de novo pathway for the formation of 1-alkyl-2-acetyl-sn-glycerols, precursors of platelet activating factor. Biochemical characterization of 1-alkyl-2-lyso-sn-glycero-3-P:acetyl-CoA acetyltransferase in rat spleen.
  Journal
J Biol Chem 261:5373-7 (1986)
Other DBs
ExplorEnz - The Enzyme Database: 3.1.3.59
IUBMB Enzyme Nomenclature: 3.1.3.59
ExPASy - ENZYME nomenclature database: 3.1.3.59
BRENDA, the Enzyme Database: 3.1.3.59
CAS: 102925-45-1

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