KEGG   ENZYME: 3.1.3.8
Entry
EC 3.1.3.8                  Enzyme                                 
Name
3-phytase;
1-phytase;
phytase;
phytate 1-phosphatase;
phytate 6-phosphatase
Class
Hydrolases;
Acting on ester bonds;
Phosphoric-monoester hydrolases
Sysname
myo-inositol-hexakisphosphate 3-phosphohydrolase
Reaction(IUBMB)
myo-inositol hexakisphosphate + H2O = 1D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate [RN:R03371]
Reaction(KEGG)
R03371
Substrate
myo-inositol hexakisphosphate [CPD:C01204];
H2O [CPD:C00001]
Product
1D-myo-inositol 1,2,4,5,6-pentakisphosphate [CPD:C04563];
phosphate [CPD:C00009]
History
EC 3.1.3.8 created 1961, modified 1976, modified 2002
Pathway
ec00562  Inositol phosphate metabolism
ec01100  Metabolic pathways
Orthology
K01083  3-phytase
Genes
MGRMGG_07789
FGRFGSG_05062
FPUFPSE_04953
FVRFVEG_06039
FOXFOXG_19847
NHENECHADRAFT_103311
PLJVFPFJ_10319
VALVDBG_05051
VDAVDAG_10379
CFJCFIO01_05441
SAPOSAPIO_CDS8497
ELAUCREL1_10252
PFYPFICI_10989
ANIAN4140.2
APUUAPUU_60360S
PCSPc22g12670
PBLPAAG_07861
PBNPADG_08223
AJEHCAG_05515
BGHBDBG_02534
PNOSNOG_10880
PTEPTT_20358
BZECOCCADRAFT_102761
BSCCOCSADRAFT_135782
BORCOCMIDRAFT_97291
AALTCC77DRAFT_750449
CCICC1G_05528
GQUAWC35_18170
BGJAWC36_15400
BIZHC231_20265
XCCXCC2384
XCBXC_1730
XCAxcc-b100_1788(phy)
XCPXCR_2674
XCVXCV2701
XAXXACM_2499
XACXAC2519
XCIXCAW_02196
XCTJ151_02696
XCJJ158_02684
XCUJ159_02682
XCNJ169_02693
XCWJ162_02685
XCRJ163_02680
XCMJ164_02682
XCFJ172_02687
XFUXFF4834R_chr25300
XAOXAC29_12805
XOMXOO2362(XOO2362)
XOOXOO2499(phy)
XOPPXO_00301
XOYAZ54_13745
XORXOC_1947
XOZBE73_09115
XVEBJD12_03615
XPEBJD13_03900
XHRXJ27_06430
XGABI317_10240
XPHXppCFBP6546_00490(XppCFBP6546P_00490)
XVAC7V42_09630
XANAC801_12815
XARXB05_07500
XHYFZ025_01860
XCZEBN15_09740
XEUXSP_002506
XHDLMG31886_17720
SMLSmlt1821
SMTSmal_1558
BUJBurJV3_1607
SMZSMD_1757
SACZAOT14_16820
STEKAXG53_01840
SRHBAY15_1619
SLMBIZ42_17080
STENCCR98_08525
STEMCLM74_08780
STESMG068_07975
SINCDAIF1_16460
SPAQSTNY_R16770
PSUPsesu_1201
PSUWWQ53_12130 WQ53_13905
PSDDSC_06385 DSC_13390
PMEXH4W19_08140 H4W19_09190
PJPLAG73_02550 LAG73_03675
PDDMNQ95_10650
LABLA76x_1503
LAQGLA29479_4331
LCPLC55x_1244 LC55x_5053
LGULG3211_1144 LG3211_5033
LEZGLE_1121 GLE_4944
LEMLEN_3794 LEN_4572
LMBC9I47_0786 C9I47_1040
LYTDWG18_03015
LUEDCD74_06680
LYJFKV23_03695
LSOLGOY17_13720 GOY17_14900
LSXH8B22_03020
LAREHIV01_001255 HIV01_017990
LHXLYSHEL_18220
LCASLYSCAS_18220
LCICINQ41_10365
LUSE5843_04370 E5843_05750
LUGFPZ22_04565
TCNH9L16_00830
DKOI596_3254
PMYPmen_4063
PALCA0T30_18305
PPUNPP4_30520
PSTPSPTO_3241
PSYRN018_11080
PSPPSPPH_2990
PAMGBKM19_018085
PCIPCH70_20780
PAVLBKM03_12855
PVDCFBP1590__2357
PCABJGS08_11530
PFLPFL_3714
PPRCPFLCHA0_c37590(phyC)
PPROPPC_3857
PFEPSF113_2829
PFSPFLU_3697
PFCPflA506_2347
PFBVO64_5643
PTVAA957_26765
PVRPverR02_12840
PAZOAYR47_19315
POIBOP93_10525
PRXHRH33_15740
PFWPF1751_v1c31360
PFFPFLUOLIPICF720540
PFXA7318_15170
PSAPST_1945
PSZPSTAB_1842
PSRPSTAA_1973
PSCA458_11100
PSJPSJM300_08700
PSHPsest_2416
PSTUUIB01_12265
PSTTCH92_07295
PCHLLLJ08_11560
PBMCL52_09350
PBAPSEBR_a2961
PBCCD58_14415
PSKU771_13140
PLQAA042_00100
PPSYAOC04_09910
PSOSPOS17_3871
PFKPFAS1_22220
PPSHG5J76_12960
PVKEPZ47_14370
PBZGN234_02595
PKHJLK41_20760
PTYJWV26_07365
PCAMHNE05_20005
PXAKSS93_13280
PSAMHU731_000180
PHVHU739_001745
PFAKKSS94_10715
PALVKSS97_15710
PTWTUM18999_07060
PZAHU749_016015
PTAENCTC10697_02567(phyC)
AVNAvin_04970
AVLAvCA_04970
AVDAvCA6_04970
ACXAchr_36150
PAGRE2H98_08835
HPEGEAO82_13070
AJORZ95_11475
AIDCTZ23_08485
AWUBEN71_05935
ACHICDG60_06380
AVBRYU24_20930
SONSO_2524(phyS)
SBNSbal195_2351
SBPSbal223_2110
SHEShewmr4_2083
SHMShewmr7_1892
SHNShewana3_2208
SWPswp_0097
SBJCF168_09795
SAVIJYB87_03045
ILOIL0102
ILIK734_00510
IPICEW91_11880
IDTC5610_06885
PHAPSHAa0438
PSMPSM_A0862
PIAPI2015_0841
PPHEPP2015_1824
PBWD172_005000
PRRAT705_22860
PALNB0W48_03805 B0W48_20480
PTDPTET_a0973
PDJD0907_11510
PAGAPAGA_a2847
PCARPC2016_0877
PVBJ5X90_19145
AMCMADE_1008500
AMHI633_08750
AMAAamad1_08895
AMALI607_07805
AMAEI876_08070
AMAOI634_08175
AMADI636_08615
AMAII635_08885
AMAGI533_08115
AMACMASE_07690
AMBAMBAS45_08275
AMGAMEC673_07780
AMKAMBLS11_07705
ALTambt_10225
ASPAOR13_1903
ASQAVL57_08240
AAWAVL56_07120
ALRDS731_12110
ALEAV939_07250
ALZAV940_07080
APELCA267_001040
SALMD0Y50_07745
GAGGlaag_0041
GPSC427_4071
PMESFX988_02576
LALAT746_04315 AT746_14660
CATEC2869_08135
FBLFbal_0098
CJACJA_0843
CEBB0D95_11200
CELLCBR65_08845
CEKD0B88_07165
CEGD0C16_12010
SDESde_3999
TTUTERTU_4617
MARQMARGE09_P0058
SPOIIMCC21906_03243
SNANI6N98_03015
MTHDA3224_12830
MICCAUP74_00355(phy)
MAGAMag101_15025
MIIBTJ40_19390
MICTFIU95_18105(phy)
MHYDGTQ55_14905
MCELLPW13_12150
KIMG3T16_01500
MEJQ7A_2162
MECQ7C_368
TIGTHII_2463
WMAWM2015_1025
HCHHCH_03662(phy)
HAHEENC22_13955
HCAMI4484_00910
ADIB5T_04065
AXEP40_19745
MMEMarme_3768
MPCMar181_0079
TOLTOL_2255
TORR615_06425
OAIOLEAN_C08240
BSANCHH28_16335
BMARHF888_13860
VCWGJQ55_04695
GSNYC6258_02964
OMEOLMES_3368
FCEJN531_006945
PBHAAW51_2658
KIAG8A07_26750
JAZYQ44_11370
JALBZG29_16270
JSVCNX70_16600
JASFJQ89_05780
JLVG3257_16900
MNRACZ75_04680
MASSCR152_31005
MASZC9I28_15910
MTIMDIR46_12060
MASYDPH57_05905
MALIEYF70_12335
MUMFCL38_06665
MFLAGO485_01680
MPLIE1742_03455
UPVEJN92_00835
UPIEJG51_005025
RGERGE_30120
RBNRBXJA2T_06075
RDPRD2015_336
PKTAT984_05420
MIUABE85_21465
RGUA4W93_07220
QAUKI612_05465
MXAMXAN_5326
MSDMYSTI_05890
MYMA176_001585
MFBMFUL124B02_31570
CCXCOCOR_02242(phy)
MFULILAB_34460
MMASMYMAC_005186
SURSTAUR_6034
AGEAA314_03549
AVMJQX13_15490 JQX13_50915
MNOMnod_1936
NTDEGO55_16190
CMETK6K41_05030
PLEOOHA_1_02105(phyC)
CCRCC_1295
CCSCCNA_01353
CSECseg_2337
CHQAQ619_12760
CMBCSW64_16285
CFHC1707_15780
CAUFCSW63_08855
PHBHYN04_01985
BSBBresu_0547
BRDJL11_03010
BRGA4249_12130
BRLBZG35_02415
BVCCEP68_05970
BDMEQG53_02125
BREVE7T10_03550
BMEDGYM46_07785
BVYNCTC9239_00143(phyC)
BVITJIP62_02305
AEXAstex_1160
TSVDSM104635_00346(phy)
MMRMmar10_2368
HNEHNE_0176
HBAHbal_0416
HBCAEM38_02670
NPPPP1Y_AT735
NPNJI59_11210
NREBES08_13470
NOVTQ38_000860
NOTC7W88_15710
NORFA702_17625
NGFFRF71_03060
SALSala_3124
SPHKSKP52_02060
SPHPLH20_06375 LH20_18240
SMAGAN936_00425 AN936_11325
SMAZLH19_12475
STERAOA14_08965
SPHQBWQ93_18235
SPHOC3E99_18805
SPHXE5675_18715
SPHUSPPYR_3191
SWISwit_0531
SPHDHY78_24040
RDICMV14_20375
SPHMG432_13470
SSANNX02_14655
SMYBJP26_13700
SKRBRX40_19595
SPLMBXU08_15870
SPKCKC8_10230
SPHCCVN68_16675
SPAPH3Z74_15210
SINBSIDU_14955
SSYSLG_11510(phy)
SYBTZ53_12110
SBDATN00_04930
SPMIK663_01855
SPHRBSY17_1112
SPHTK426_04030
SHYDCJD35_07015
SYAA6768_24655
SCLOSCLO_1023850
SPYGYGS_C1P3031
SUFLFIL70_18040
SBARH5V43_15710
SAMISAMIE_1024690
CIJWG74_07755
SPHGAZE99_05370
SFLASPHFLASMR4Y_01278(phy)
SPHYCHN51_17780
BLASBSY18_1171
BFWB5J99_15205
SPHJBSL82_02930
SPZRG5C33_09600
PALGHFP57_00365
PARJJ4G78_10575
SMICSmB9_06990
SPHSETR14_04520
ALBAEB_P1165
ALHG6N82_01265
AAYWYH_02975(phy)
AMXAM2010_2372
CNAAB433_05050
CMANA9D14_03810
ERYCP97_03550
EGNBMF35_a0871
EFVCHH26_11505
ELQGa0102493_111606
ERKCD351_04525
ERRDVR09_06950
PNSA9D12_07555
PORLBG023_11911
PHZCHX26_05520
POTE2E27_17165
NCBC0V82_17565 C0V82_25530
SKTIGS68_19040
SMUCJL100_006960
SROEJL101_006820
RCERC1_0294(phy)
PBRPB2503_07007
ECOGFIV45_03100
BSUBSU19800(phy)
BSRI33_2224
BSLA7A1_2852
BSHBSU6051_19800(phy)
BSYI653_10280
BSUTBSUB_02134(phy)
BSULBSUA_02134(phy)
BSUSQ433_11790
BSOBSNT_08555(phy)
BSNBSn5_01290
BSQB657_19800(phy)
BSXC663_2039(phy)
BSPU712_10465
BSSBSUW23_10595(phy)
BSTGYO_2389
BLIBL01844(phyL)
BLDBLi00448(phy)
BLHBaLi_c04690(phy)
BAYRBAM_019640(phyC)
BAQBACAU_1965(phy)
BYABANAU_2089(phy)
BAMPB938_10180
BQYMUS_2344(phy)
BAMLBAM5036_1897(phy)
BAMARBAU_1934(phy)
BAMNBASU_1914(phy)
BAMBBAPNAU_1780(phy)
BAMTAJ82_11155
BAMYV529_21880(phy)
BMPNG74_02044(phy)
BAOBAMF_2062(phy)
BAZBAMTA208_07190(phy)
BQLLL3_02166(phy)
BXHBAXH7_01462(phy)
BAMIKSO_009520
BAMCU471_20290
BAMFU722_10715
BSIACWD84_11185
BAEBATR1942_08630
BVMB9C48_10005
BSONS101395_04578
BHTDIC78_20665
BMOJHC660_20460(phyC)
BIQAN935_10520
BMYCDJ92_3582(phy)
BJSMY9_2170
BACPSB24_18875
BACBOY17_12950
BACYQF06_09040
BACLBS34A_21980(phy)
BALMBsLM_2108
BGYBGLY_0462
BACSAUL54_00580
BITBIS30_00455
PARHI5S86_17095
BGIBGM20_04520
PPYPPE_00217
PPMPPSC2_01355(phy)
PPOPPM_0252(phy)
PPOLX809_00805
PPQPPSQR21_002160(phy)
PPOYRE92_10545
PMSKNP414_00893 KNP414_05503
PMQPM3016_4874 PM3016_786
PMWB2K_04010 B2K_25260
PTAHPL003_08630
PGMPGRAT_31960
PAEHH70357_34680
PSONJI735_08170
PPEOABE82_01130
PKBB4V02_24130
PAIHASL14_10770
PCHIPC41400_26530
PFTJBW_01433
SCOSCO7697(SC1A4.05)
SCBSCAB_84251
SFASfla_0742
SVESVEN_0101
SDVBN159_7413
STRPF750_6120
SFISFUL_219
SLVSLIV_00815
SGUSGLAU_29110 SGLAU_30440
SCWTU94_32000
STRMM444_32765
SPRISPRI_4173
SRWTUE45_00102(phy)
SLEsle_04290(sle_04290)
SRNA4G23_04511(phyC)
SALWCP975_03630
STRDNI25_00345
SNWBBN63_19770
SSIAA7J05_31335
SALFSMD44_01315 SMD44_08654
SFKKY5_6574
SLKSLUN_36435
SCYAEJ357_04575
STIRDDW44_05145
SKACP970_08265
SGZC0216_14525
SNKCP967_02815
SFICEIZ62_31385
SGALCP966_34400
SSPODDQ41_16790
SBYH7H31_03110
SRIMCP984_39095
SSUBCP968_28575
SPHVF9278_02550
SCINCP977_01765
SCHACP983_04665
SGXH4W23_04505
SCOECP976_41350
SBATG4Z16_02605
SSPBCP982_37550
SNFJYK04_07992(phy)
SFEUIM697_19370
SFBCP974_24255
SXNIAG42_02855
SGJIAG43_16365
SHKJ2N69_03575
SACTDMT42_02165
ARUASPU41_16125
ARQBWQ92_20665
ARTHC3B78_09960
MUZH4N58_08260
KFLKfla_3849 Kfla_6868
NALB005_4438
SROSros_5553
NOABKM31_10605
NOWGBF35_48695
NGNLCN96_33020
KRAKrad_2879
AMDAMED_2281
AMNRAM_11615
AMMAMES_2255
AMZB737_2256
AOIAORI_5644
AJAAJAP_11250
AABA4R43_17270
AMYYYIM_12770(phy)
AORISD37_27575
SESPBN6_15790
SSYIEKG83_07675
KALKALB_3659
KPHYAOZ06_49080
LEDBBK82_02745
ALOCRK56266
MICHFJK98_30445
MCABHXZ27_29235
ASEACPL_259(phy)
AMSAMIS_1520
ACTSACWT_0144
AIHAiant_44410
PFLAPflav_045840
PSUUPsuf_003410
PRYPrubr_06950
CATICS0771_10520
SNASnas_5955
GLYK3N28_22130
AEYCDG81_21110
CMPCha6605_2480
LSCKIK02_04785
LSKJ5X98_01700
GLPGlo7428_1096
CHONNIES4102_09510
HAOPCC7418_2684
CYPPCC8801_4199
CYHCyan8802_4238
CYNCyan7425_1644
MVAGD0A34_16855
GVIgll2099
GLJGKIL_2540
GMLISF26_12540
ANAalr4238
NPUNpun_R6594
NOPNos7524_1774 Nos7524_2967
NONNOS3756_38800
NFLCOO91_00480
NOECLI64_11620
NSHGXM_06899
NEDHUN01_16735
AVAAva_3999
ACYAnacy_4976 Anacy_4977
ANNEH233_03635
CSGCylst_0653
RSINB6N60_03135
FISFIS3754_27940
NSPBMF81_00383
CCURIAR63_06820
DMRDeima_0470
DPTDeipr_0854
DWUDVJ83_13825
DRDLMT64_12320
SNGSNE_A06590(phy)
OBGVerru16b_01485(phy)
VBHCMV30_16150
LUOHHL09_25385
SDYNMal52_31710(phy)
GMSSOIL9_73820
FTJFTUN_2011
SACISinac_3868
PBORBSF38_00685(phy)
AGVOJF2_68940(phyC)
GAUGAU_2676
GPHGEMMAAP_05290
PETPEIBARAKI_4011
MCOSGM418_08850
CPICpin_1035
CBAECOR50_10845
CHITFW415_21040
CHIHGWR21_20740
PSEGD3H65_28380
PGOFSB84_02530
HHYHalhy_2627
PEPAQ505_24820
PCMAY601_1374
PSTYBFS30_11245
PEKFFJ24_013975
SHGSph21_4643
SHTKO02_16870
SPHNBV902_15650
SMIZ4412673_01012(phyC)
SPSCE2P86_13460
SPHZE3D81_10890
SPHEGFH32_13605
SPDRG6053_12695
SDJNCTC13534_01397(phyC)
STHANCTC11429_01313(phyC)
SSPII6J01_17060
SMUII6J00_04315
SSIYJVX97_17010
MUPA0256_15750
MUHHYN43_029060
MRUBDEO27_022500
OLIFKG96_20980
SBXCA265_13590
EVIEchvi_4536
ESTDN752_05855
ECHIFKX85_17650
SLISlin_2400
SRDSD10_09840
SPIRCWM47_01205
SPIKEXU85_29820
SPIBG8759_22960
DFEDfer_4719
FAEFAES_0335
ASWUHUW51_16395
FPFDCC35_14875
CHKD4L85_03155 D4L85_29035
FUVJR347_11165
FPSZAMR72_11735
FJOFjoh_1367
FJGBB050_01247(phy)
FCMBIW12_08675
FCRHYN56_07070
FSEDI487_14265
FAKFUA48_05370
FFLHYN86_06320
FENJ0383_09090
CCMCcan_23510
ZPRZPR_4475
CAOCelal_1080
CLYCelly_1016
CLHIX49_04900
CBALM667_03275
CBATM666_03255
ZGAZOBELLIA_1354(phyC)
MUTGVT53_15620
MAQILDL77_07215
PRNBW723_10220
POACW731_06515
MODAS202_12025
MYZBK054_11630
WINWPG_1627
AHZAPS56_11930
TMPF9Y86_11865
LULLPB138_11995
WFUAXE80_07740
FOHFORMA_10650
FOPFNB79_05490
SEONBWZ22_05250
AALGAREALGSMS7_02051(phyC)
OAQDZC78_11615
FEKC1H87_14485
TAJC1A40_09045
MARFCJ739_1317
AQAD1815_15055
CAGGHYG79_09800
FBEFF125_20530
RANRiean_1480
RAIRA0C_1761
RARRIA_0728(phyL)
RAGB739_0390
RAEG148_0071
RATM949_0836
WVIWeevi_1206
EENBBD30_18085
ELBVO54_00999(phy)
EMGBBD33_13655
EGOBBD34_16900
EGMAYC65_09690
ELZFCS00_02560
ELTFGE20_00505
CHZCHSO_2126
CGNOK18_16155
CHHA0O34_00150
CHRYCEY12_01805
CNKEG343_24615
CJTEG359_00865
CCAUEG346_21430
CBENEG339_15730
CGLENCTC11432_00222(phy)
CLACEG342_15720
CTAK4412677_00867(phyC)
EVAEIB75_06915
CNREB819_07225
EBVF0358_14620
EFALFH779_09525
ESTEHNV03_04580
CIVIMZ16_03860
OHOOweho_2524
CPBCphamn1_1536
CLIClim_1122
PAAPaes_0101
PROCPtc2401_01855(phy)
CTSCtha_1282
 » show all
Reference
1  [PMID:4310381]
  Authors
Cosgrove DJ.
  Title
Ion-exchange chromatography of inositol polyphosphates.
  Journal
Ann N Y Acad Sci 165:677-86 (1969)
DOI:10.1111/j.1749-6632.1970.tb56434.x
Reference
2  [PMID:4310376]
  Authors
Johnson LF, Tate ME.
  Title
The structure of myo-inositol pentaphosphates.
  Journal
Ann N Y Acad Sci 165:526-32 (1969)
DOI:10.1111/j.1749-6632.1970.tb56420.x
Reference
3  [PMID:4342816]
  Authors
Irving GC, Cosgrove DJ.
  Title
Inositol phosphate phosphatases of microbiological origin: the inositol pentaphosphate products of Aspergillus ficuum phytases.
  Journal
J Bacteriol 112:434-8 (1972)
DOI:10.1128/JB.112.1.434-438.1972
Reference
4
  Authors
Cosgrove, D.J.
  Title
Inositol Phosphates: Their Chemistry, Biochemistry, and Physiology, Elsevier, Amsterdam, 1980
Other DBs
ExplorEnz - The Enzyme Database: 3.1.3.8
IUBMB Enzyme Nomenclature: 3.1.3.8
ExPASy - ENZYME nomenclature database: 3.1.3.8
BRENDA, the Enzyme Database: 3.1.3.8
CAS: 37288-11-2

DBGET integrated database retrieval system