KEGG   ENZYME: 3.1.3.84
Entry
EC 3.1.3.84                 Enzyme                                 
Name
ADP-ribose 1''-phosphate phosphatase;
POA1;
Appr1p phosphatase;
Poa1p;
ADP-ribose 1''-phosphate phosphohydrolase
Class
Hydrolases;
Acting on ester bonds;
Phosphoric-monoester hydrolases
Sysname
ADP-D-ribose 1''-phosphate phosphohydrolase
Reaction(IUBMB)
ADP-D-ribose 1''-phosphate + H2O = ADP-D-ribose + phosphate
Substrate
ADP-D-ribose 1''-phosphate;
H2O [CPD:C00001]
Product
ADP-D-ribose [CPD:C00301];
phosphate [CPD:C00009]
Comment
The enzyme is highly specific for ADP-D-ribose 1''-phosphate. Involved together with EC 3.1.4.37, 2',3'-cyclic-nucleotide 3'-phosphodiesterase, in the breakdown of adenosine diphosphate ribose 1'',2''-cyclic phosphate (Appr>p), a by-product of tRNA splicing.
History
EC 3.1.3.84 created 2011
Orthology
K15529  ADP-ribose 1''-phosphate phosphatase
Genes
SCE: YBR022W(POA1)
SEUB: DI49_0201
SPAO: SPAR_B01260
LTH: KLTH0A01892g
VPO: Kpol_1037p48
ZRO: ZYRO0A04070g
CGR: 2886571(GVI51_B04345)
NCS: NCAS_0A10220(NCAS0A10220)
NDI: NDAI_0A07250(NDAI0A07250)
TPF: TPHA_0A04210(TPHA0A04210)
TBL: TBLA_0I01770(TBLA0I01770)
KAF: KAFR_0F02400(KAFR0F02400)
KNG: KNAG_0K01580(KNAG0K01580)
ZMK: HG535_0C02170
SLUD: SCDLUD_005050
DHA: DEHA2E12188g
PIC: PICST_49619
PGU: PGUG_05704
SPAA: SPAPADRAFT_55534
LEL: PVL30_004553(POA1)
LBG: 92205242(LODBEIA_P00460) 92206318(LODBEIA_P11220) 92206409(LODBEIA_P12130) 92207270(LODBEIA_P20740) 92208319(LODBEIA_P31230) 92209078(LODBEIA_P38820) 92209888(LODBEIA_P46920) 92209979(LODBEIA_P47830) 92210912(LODBEIA_P57160)
CAL: CAALFM_C501200WA(CaO19.1950)
CTP: CTRG_05372
COT: CORT_0E06090
CDU: CD36_51150
CLU: CLUG_00853
CLUS: A9F13_10g01309
CAUR: CJI96_0001149
ASAU: 88173585(PUMCH_002520)
PPA: PAS_chr2-1_0070
PKZ: C5L36_0A12770
BNN: FOA43_000108
BBRX: BRETT_000991
YLI: 2906499(YALI2_A00103g)
TTT: THITE_2123227
MTM: MYCTH_2311508
CTHR: CTHT_0006790
RTHE: 98127644(VTJ83DRAFT_6303)
MGR: MGG_10088
PPEI: PpBr36_06761
PGRI: PgNI_10052
TMN: UCRPA7_1210
FGR: FGSG_03990
FPU: FPSE_05287
FPOA: FPOAC1_006418
FVN: FVRRES_07025
FVR: FVEG_10152
FOX: FOXG_11670
NHE: NECHADRAFT_42552
FFC: NCS54_00774000
FKR: NCS57_00816100
PCHM: VFPPC_05396
CMT: CCM_02762
AMUS: LMH87_008955
PLJ: 28885285(PLICBS_006857)
PSCO: LY89DRAFT_703231
AFM: AFUA_1G16556
ACT: ACLA_019030
NFI: NFIA_008880
AOR: AO090005001055
AFV: AFLA_003880
ALUC: AKAW2_10537A(POA1_1)
ACHE: ACHE_30783A(POA1)
APUU: APUU_50829S(POA1)
PDP: PDIP_05140
POU: POX_c03572
TMF: EYB26_009473
TRG: TRUGW13939_02216
CIM: CIMG_03039 CIMG_07351
CPW: 9694541(POA1)
URE: UREG_02916
PBL: PAAG_09129
PBN: PADG_06611
AJE: HCAG_02197
BGH: BDBG_07577
PNO: SNOG_08844
PTE: PTT_15013
PTRR: 6341352(PtrM4_067300)
BZE: COCCADRAFT_39583
BSC: COCSADRAFT_106376
BOR: COCMIDRAFT_49250
AALT: CC77DRAFT_1020829
ADAC: 96083177(ACET3X_002855)
ARAB: EKO05_0008999
ZTR: MYCGRDRAFT_28514
PFJ: MYCFIDRAFT_212330
FFU: CLAFUR5_11556
CBET: CB0940_07193
BCOM: BAUCODRAFT_43663
NPA: UCRNP2_6358
ADL: AURDEDRAFT_71338
PCUB: JR316_0007182
MORE: E1B28_012905
 » show all
Reference
1  [PMID:15684411]
  Authors
Shull NP, Spinelli SL, Phizicky EM
  Title
A highly specific phosphatase that acts on ADP-ribose 1''-phosphate, a metabolite of tRNA splicing in Saccharomyces cerevisiae.
  Journal
Nucleic Acids Res 33:650-60 (2005)
DOI:10.1093/nar/gki211
  Sequence
[sce:YBR022W]
Other DBs
ExplorEnz - The Enzyme Database: 3.1.3.84
IUBMB Enzyme Nomenclature: 3.1.3.84
ExPASy - ENZYME nomenclature database: 3.1.3.84
BRENDA, the Enzyme Database: 3.1.3.84

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Gene (6)   
   RefGene (6)   
Protein sequence (3186)   
   UniProt (2754)   
   SWISS-PROT (45)   
   RefSeq(pep) (15)   
   PDBSTR (372)   
DNA sequence (44)   
   RefSeq(nuc) (30)   
   GenBank (6)   
   EMBL (8)   
3D Structure (94)   
   PDB (94)   
Protein domain (18)   
   InterPro (18)   
All databases (3348)   

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