KEGG   ENZYME: 3.1.3.87Help
Entry
EC 3.1.3.87                 Enzyme                                 

Name
2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase;
HK-MTPenyl-1-P phosphatase;
MtnX;
YkrX;
2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate phosphohydrolase
Class
Hydrolases;
Acting on ester bonds;
Phosphoric-monoester hydrolases
BRITE hierarchy
Sysname
2-hydroxy-5-(methylsulfanyl)-3-oxopent-1-enyl phosphate phosphohydrolase
Reaction(IUBMB)
2-hydroxy-5-(methylsulfanyl)-3-oxopent-1-enyl phosphate + H2O = 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + phosphate [RN:R07394]
Reaction(KEGG)
Substrate
2-hydroxy-5-(methylsulfanyl)-3-oxopent-1-enyl phosphate [CPD:C15651];
H2O [CPD:C00001]
Product
1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one [CPD:C15606];
phosphate [CPD:C00009]
Comment
The enzyme participates in the methionine salvage pathway in Bacillus subtilis [2].In some species a single bifunctional enzyme, EC 3.1.3.77, acireductone synthase, catalyses both this reaction and EC 5.3.2.5, 2,3-diketo-5-methylthiopentyl-1-phosphate enolase [1].
History
EC 3.1.3.87 created 2012
Pathway
ec00270  Cysteine and methionine metabolism
ec01100  Metabolic pathways
Orthology
K08966  2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase
Genes
PGE: LG71_26585
EPE: CI789_09945
ERWI: GN242_08425
XAL: XALC_1785
XSA: SB85_20205
XTN: FD63_09200
XVA: C7V42_21070
XHY: FZ025_01690
SML: Smlt1416
SMT: Smal_1184
SMZ: SMD_1254(mtnX)
LEM: LEN_0213
RBD: ALSL_1571
PFL: PFL_4883
PPRO: PPC_4892
PFS: PFLU_1127
PFB: VO64_4244
PMAN: OU5_4734
PSEM: TO66_24985
PSOS: POS17_4859
PANR: A7J50_1125
AGU: AS4_21000(mtnX)
LFA: LFA_0341
LCJ: NCTC11976_02520(mtnX)
SALN: SALB1_0753
AAV: Aave_4326
AAA: Acav_4229
DAC: Daci_0129
CTES: O987_00710
OFO: BRW83_0701(mtnX)
MEH: M301_1786
MEP: MPQ_1274
DGG: DGI_1036
DAL: Dalk_2418
ADE: Adeh_0655
SCL: sce2820
ARA: Arad_4498
AVI: Avi_5523
XAU: Xaut_1041
AZC: AZC_3989
AFR: AFE_0435
ACU: Atc_2429
ATX: GCD22_00527(mtnX)
BSU: BSU13600(mtnX)
BSR: I33_1531(mtnX)
BSL: A7A1_1504
BSH: BSU6051_13600(mtnX)
BSY: I653_06980(mtnX)
BSUT: BSUB_01480(mtnX)
BSUL: BSUA_01480(mtnX)
BSUS: Q433_07775(mtnX)
BSS: BSUW23_06985(mtnX)
BST: GYO_1687(mtnX)
BSO: BSNT_07851(mtnX)
BSN: BSn5_18845(mtnX)
BSQ: B657_13600(mtnX)
BSX: C663_1401(mtnX)
BLI: BL00251 BL03541(mtnB)
BLD: BLi01516(mtnB_mtnX) BLi04260
BAY: RBAM_013380(mtnX)
BAQ: BACAU_1315(mtnX)
BYA: BANAU_1274(mtnX)
BAMP: B938_06960(mtnX)
BAML: BAM5036_1274(mtnX)
BAMA: RBAU_1316(mtnX)
BAMN: BASU_1295(mtnX)
BAMB: BAPNAU_2425(mtnX)
BAMT: AJ82_07685(mtnX)
BAMY: V529_12900(mtnX)
BMP: NG74_01394(mtnX)
BAZ: BAMTA208_10335(mtnX)
BQL: LL3_01462(mtnX)
BXH: BAXH7_02113(mtnX)
BQY: MUS_1441(mtnX)
BAMI: KSO_012675(mtnX)
BAMC: U471_13610
BAMF: U722_07150(mtnX)
BAE: BATR1942_04555(mtnX)
BAN: BA_4256(mtnX)
BAR: GBAA_4256(mtnX)
BAT: BAS3947(mtnX)
BAH: BAMEG_4297(mtnX)
BAI: BAA_4279(mtnX)
BANT: A16_42570
BANR: A16R_43110
BANS: BAPAT_4081
BANH: HYU01_20795(mtnX)
BANV: DJ46_2948(mtnX)
BCE: BC4037(mtnX)
BCA: BCE_4104
BCR: BCAH187_A4168(mtnX)
BCB: BCB4264_A4146(mtnX)
BCU: BCAH820_4058(mtnX)
BCG: BCG9842_B1092(mtnX)
BCQ: BCQ_3827
BCX: BCA_4150(mtnX)
BNC: BCN_3949
BCF: bcf_20080
BCER: BCK_15015(mtnX)
BTK: BT9727_3779(mtnX)
BTL: BALH_3654
BTB: BMB171_C3701(mtnX)
BTT: HD73_4336
BTHR: YBT1520_21495(mtnX)
BTHI: BTK_21345(mtnX)
BTC: CT43_CH4043(mtnX)
BTF: YBT020_19875(mtnX)
BTM: MC28_3329(mtnX)
BTG: BTB_c41720(mtnX)
BTI: BTG_29235(mtnX)
BTN: BTF1_18500(mtnX)
BTHU: YBT1518_22365(mtnX)
BTW: BF38_5210(mtnX)
BTHY: AQ980_09665(mtnX)
BWW: bwei_0914(mtnX)
BMYO: BG05_1985(mtnX)
BMYC: DJ92_1132(mtnX)
BBY: CY96_19275(mtnX)
BPU: BPUM_1253(mtnX)
BPUM: BW16_07070(mtnX)
BPUS: UP12_06575(mtnX)
BPF: BpOF4_14680(mtnX)
BMQ: BMQ_1251(mtnX) BMQ_2498
BMD: BMD_1235(mtnX) BMD_2485
BMH: BMWSH_2710(ykrX) BMWSH_3985(mtnX)
BMEG: BG04_3550(mtnX) BG04_4945
BJS: MY9_1489
BIF: N288_08400(mtnX)
BMET: BMMGA3_05050(mtnX)
GST: HW35_15690(mtnX)
BACW: QR42_06430(mtnX)
BACP: SB24_03025(mtnX)
BACB: OY17_09785(mtnX)
BACY: QF06_05810(mtnX)
BACL: BS34A_15110(mtnX)
BALM: BsLM_1441
BEO: BEH_04820
BSJ: UP17_14155(mtnX)
BKW: BkAM31D_06400(mtnX)
BBEV: BBEV_1650(mtnX)
BACS: AUL54_03850(mtnX)
BIT: BIS30_17600(mtnX)
GKA: GK0954
GTK: GT3570_04595(mtnX)
GTN: GTNG_0842
GGH: GHH_c08910(mtnX)
GJF: M493_04890(mtnX)
GEA: GARCT_00966(mtnX)
GEL: IB49_15050(mtnX)
GSE: GT50_14455(mtnX)
GSR: GS3922_11655(mtnX)
GEJ: A0V43_02070(mtnX)
PTL: AOT13_07935(mtnX)
PTB: DER53_08880(mtnX)
ANM: GFC28_1479(mtnX)
AAMY: GFC30_1263(mtnX)
ANL: GFC29_149(mtnX)
LSP: Bsph_4351
LGY: T479_21680(mtnX)
LFU: HR49_02430(mtnX)
LYS: LBYS11_20865(mtnX)
HHD: HBHAL_2664(mtnX)
FPN: ABE65_007250(mtnX)
PSYO: PB01_20420
BSE: Bsel_1935
MCAK: MCCS_23720(mtnX)
ESI: Exig_0429
EAN: Eab7_0404(mtnX)
EXM: U719_02205(mtnX)
BBE: BBR47_48910(mtnX)
PPY: PPE_02690(mtnX)
PPM: PPSC2_14330(ykrX)
PPO: PPM_2882(ykrX)
PPOL: X809_30755(mtnX)
PPOY: RE92_22370(mtnX)
PMS: KNP414_04027(mtnX)
PMW: B2K_27875(mtnX)
PTA: HPL003_23130(mtnX)
PLV: ERIC2_c14180(mtnX)
PSAB: PSAB_03675
PBJ: VN24_24485(mtnX)
PIH: UB51_05765(mtnX)
PPEO: ABE82_14770(mtnX)
PSWU: SY83_18320(mtnX)
PAIH: ASL14_23610(mtnX)
PVO: PVOR_13849(mtnX)
ANX: ACH33_15415(mtnX)
ASOC: CB4_03886(mtnX)
COHN: KCTCHS21_26510(mtnX)
AAC: Aaci_0097
AAD: TC41_0119(mtnX)
JEO: JMA_33130
SURE: SporoP32a_07275(mtnX)
CPAS: Clopa_4396
CSQ: CSCA_2623
CACE: CACET_c22050(mtnX)
CCE: Ccel_2487
STH: STH1897
SALQ: SYNTR_0090
DHD: Dhaf_2521
DAE: Dtox_1672
PTH: PTH_0926
ELM: ELI_1882
SAY: TPY_2540(mtnX)
THX: Thet_2233
TIT: Thit_2133
TKI: TKV_c21900(mtnX)
TPZ: Tph_c17770(mtnX)
TOC: Toce_0247
TTM: Tthe_0264
TSH: Tsac_0824
TACI: TDSAC_0146
PFT: JBW_02584
SYC: syc1010_d
PSER: ABRG53_0206(mtnX)
MAR: MAE_51120
MPK: VL20_1992
NSH: GXM_09633
CALH: IJ00_05195
DET: DET0759
DEH: cbdbA732
DEV: DhcVS_665
DMC: btf_681
DMD: dcmb_727
DMG: GY50_0644
DFO: Dform_00823(mtnX)
TTR: Tter_0864
PIR: VN12_10040(mtnX)
EMI: Emin_0373
LBA: Lebu_2250
IAL: IALB_0346(mtnX)
MRO: MROS_1840
LFC: LFE_0828
 » show all
Taxonomy
Reference
1  [PMID:8227039]
  Authors
Myers RW, Wray JW, Fish S, Abeles RH.
  Title
Purification and characterization of an enzyme involved in oxidative carbon-carbon bond cleavage reactions in the methionine salvage pathway of Klebsiella pneumoniae.
  Journal
J Biol Chem 268:24785-91 (1993)
Reference
2  [PMID:14551435]
  Authors
Ashida H, Saito Y, Kojima C, Kobayashi K, Ogasawara N, Yokota A
  Title
A functional link between RuBisCO-like protein of Bacillus and photosynthetic RuBisCO.
  Journal
Science 302:286-90 (2003)
DOI:10.1126/science.1086997
  Sequence
[bsu:BSU13600]
Other DBs
ExplorEnz - The Enzyme Database: 3.1.3.87
IUBMB Enzyme Nomenclature: 3.1.3.87
ExPASy - ENZYME nomenclature database: 3.1.3.87
BRENDA, the Enzyme Database: 3.1.3.87

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