KEGG   ENZYME: 3.1.3.93Help
Entry
EC 3.1.3.93                 Enzyme                                 

Name
L-galactose 1-phosphate phosphatase;
VTC4 (gene name) (ambiguous);
IMPL2 (gene name) (ambiguous)
Class
Hydrolases;
Acting on ester bonds;
Phosphoric-monoester hydrolases
BRITE hierarchy
Sysname
beta-L-galactose-1-phosphate phosphohydrolase
Reaction(IUBMB)
beta-L-galactose 1-phosphate + H2O = L-galactose + phosphate [RN:R07674]
Reaction(KEGG)
Substrate
beta-L-galactose 1-phosphate [CPD:C15926];
H2O [CPD:C00001]
Product
L-galactose [CPD:C01825];
phosphate [CPD:C00009]
Comment
The enzyme from plants also has the activity of EC 3.1.3.25, inositol-phosphate phosphatase. The enzymes have very low activity with D-galactose 1-phosphate (cf. EC 3.1.3.94, D-galactose 1-phosphate phosphatase).
History
EC 3.1.3.93 created 2014
Pathway
ec00053  Ascorbate and aldarate metabolism
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K10047  inositol-phosphate phosphatase / L-galactose 1-phosphate phosphatase
K18649  inositol-phosphate phosphatase / L-galactose 1-phosphate phosphatase / histidinol-phosphatase
Genes
AQU: 100635967
ATH: AT3G02870(VTC4) AT4G39120(IMPL2)
ALY: ARALYDRAFT_477531 ARALYDRAFT_490680
CRB: 17879544 17892437
CSAT: 104716190 104720823 104729217 104744369 104756767 104763907 104779537
EUS: EUTSA_v10021317mg EUTSA_v10025644mg
BRP: 103835143(VTC4) 103870884
BNA: 106353357 106361489 106406767 106443867 106447599 106453198 106453206
BOE: 106293897 106332503 106336071
THJ: 104807751 104812780 104815485
LJA: Lj1g3v3381210.1(Lj1g3v3381210.1) Lj1g3v3381210.2(Lj1g3v3381210.2) Lj4g3v0119960.1(Lj4g3v0119960.1) Lj6g3v1753250.1(Lj6g3v1753250.1)
SLY: 101254644 544013(IMP3) 544014(IMP2) 544280(IMP1)
DOSA: Os03t0587000-01(Os03g0587000) Os07t0191000-01(Os07g0191000) Os09t0322900-00(Os09g0322900)
ATS: 109738639(LOC109738639) 109768500(LOC109768500)
DDI: DDB_G0281239(impa1)
DFA: DFA_07272(impa1)
NGD: NGA_0525100(IMPA)
MGRY: MSR1_25420(hisN)
MAGN: WV31_04510
 » show all
Taxonomy
Reference
1  [PMID:15550539]
  Authors
Laing WA, Bulley S, Wright M, Cooney J, Jensen D, Barraclough D, MacRae E
  Title
A highly specific L-galactose-1-phosphate phosphatase on the path to ascorbate biosynthesis.
  Journal
Proc Natl Acad Sci U S A 101:16976-81 (2004)
DOI:10.1073/pnas.0407453101
  Sequence
Reference
2  [PMID:19339506]
  Authors
Torabinejad J, Donahue JL, Gunesekera BN, Allen-Daniels MJ, Gillaspy GE
  Title
VTC4 is a bifunctional enzyme that affects myoinositol and ascorbate biosynthesis in plants.
  Journal
Plant Physiol 150:951-61 (2009)
DOI:10.1104/pp.108.135129
  Sequence
Reference
3  [PMID:20023146]
  Authors
Petersen LN, Marineo S, Mandala S, Davids F, Sewell BT, Ingle RA
  Title
The missing link in plant histidine biosynthesis: Arabidopsis myoinositol monophosphatase-like2 encodes a functional histidinol-phosphate phosphatase.
  Journal
Plant Physiol 152:1186-96 (2010)
DOI:10.1104/pp.109.150805
  Sequence
[ath:AT4G39120]
Other DBs
ExplorEnz - The Enzyme Database: 3.1.3.93
IUBMB Enzyme Nomenclature: 3.1.3.93
ExPASy - ENZYME nomenclature database: 3.1.3.93
BRENDA, the Enzyme Database: 3.1.3.93

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