KEGG   ENZYME: 3.1.3.96
Entry
EC 3.1.3.96                 Enzyme                                 
Name
pseudouridine 5'-phosphatase;
pseudouridine 5'-monophosphatase;
5'-PsiMPase;
HDHD1
Class
Hydrolases;
Acting on ester bonds;
Phosphoric-monoester hydrolases
Sysname
pseudouridine 5'-phosphohydrolase
Reaction(IUBMB)
pseudouridine 5'-phosphate + H2O = pseudouridine + phosphate [RN:R11180]
Reaction(KEGG)
R11180
Substrate
pseudouridine 5'-phosphate [CPD:C01168];
H2O [CPD:C00001]
Product
pseudouridine [CPD:C02067];
phosphate [CPD:C00009]
Comment
Requires Mg2+ for activity.
History
EC 3.1.3.96 created 2014
Orthology
K17623  pseudouridine 5'-phosphatase
Genes
HSA8226(PUDP)
PTR465476(PUDP)
PPS100979285(PUDP)
GGO101133677(PUDP)
PON100438722(PUDP)
NLE100582921(PUDP) 100596451 100596611
MCC693664 707930(PUDP)
MCF102117354 102139585
CSAB103231565(PUDP)
CATY105574748(HDHD1) 105590306
PANU101007310(PUDP)
TGE112612050 112615386(PUDP)
RRO104655515(PUDP) 104662310
RBB108512226(PUDP) 108533302
TFN117074381 117078218(PUDP)
PTEH111536233(PUDP) 111543570
CJC100385213(PUDP)
SBQ101040474 101052173(HDHD1)
CSYR103261433(PUDP)
MMUR105881030(PUDP)
OGA100950219(PUDP)
MMU67365(Pudp)
MCAL110284960(Pudp)
MPAH110333531(Pudp)
RNO291585(Pudp)
MCOC116087643(Pudp)
MUN110541460 110542332(Pudp)
CGE100761202 100774390(Pudp)
PLEU114689710 114694790
NGI103751215(Pudp)
HGL101718666(Pudp)
CPOC100715095 100717999 100736076(Pudp)
CCAN109675118(Pudp)
DORD105991141 106000187(Hdhd1) 106002782
DSP122101929 122102654 122102693 122107159 122123186 122127961 122128098
OCU100351410(PUDP)
OPI101523787
TUP102472702 102497229(PUDP)
CFA610678(PUDP)
VVP112932360(PUDP)
VLG121482967
AML100484137(PUDP)
UMR103666314(PUDP)
UAH113240764(PUDP)
UAR123802777
ELK111157128
LLV125091420
MPUF101686245(HDHD1)
ORO101383920(HDHD1)
EJU114218029(PUDP)
ZCA113930608
MLX118026689(PUDP)
FCA101082722(PUDP)
PYU121020213
PBG122477938
PTG102958111(PUDP)
PPAD109248262(PUDP)
AJU113596628(PUDP)
HHV120235972
BTA617253(PUDP)
BOM102288393(PUDP)
BIU109555257(PUDP)
BBUB102404822(PUDP)
CHX102186947(PUDP)
OAS101118336(PUDP)
ODA120882379
CCAD122434704
SSC100521877(PUDP)
CFR102521294(PUDP)
CBAI105075985(HDHD1)
CDK105086568(PUDP)
VPC102544791(PUDP)
BACU103014542
LVE103082730(PUDP)
OOR101286515(HDHD1)
DLE111167222(PUDP)
PCAD102976113(PUDP)
PSIU116747749(PUDP)
ECB100052784(PUDP)
EPZ103543337(PUDP)
EAI106832482
MYB102244694(PUDP)
MYD102774977(PUDP)
MMYO118657324
MNA107533008(PUDP)
PKL118721081
HAI109371891(PUDP)
DRO112313397(PUDP)
SHON118974307
AJM119058292
PDIC118498602
PHAS123829995
MMF118636566
RFQ117021639(PUDP)
PALE102881789(PUDP)
PGIG120584069
PVP105308973
RAY107499526
MJV108397176(PUDP)
TOD119246363
SARA101554541(HDHD1)
LAV100661574(PUDP)
TMU101350225
DNM101427140(PUDP)
MDO100032216(PUDP)
GAS123242559 123250466 123251326 123253488
SHR100928191(PUDP)
PCW110221515(PUDP)
OAA100084333
GGA418655(PUDP)
PCOC116230770(PUDP)
MGP100542359(PUDP)
CJO107306115(PUDP)
NMEL110405633(PUDP)
APLA101800629(PUDP)
ACYG106040527(HDHD1)
AFUL116495927(PUDP)
TGU100220897(PUDP)
LSR110476186(PUDP)
SCAN103812413(PUDP)
PMOA120504699
OTC121342245
PRUF121356188
GFR102043023(PUDP)
FAB101812869(PUDP)
PHI102101314(PUDP)
PMAJ107204520(PUDP)
CCAE111922774(PUDP)
CCW104686134
ETL114065004(PUDP)
ZAB102061949(PUDP)
FPG101915798(PUDP)
FCH102056416(PUDP)
CLV102092766(PUDP)
EGZ104127464(HDHD1)
NNI104014012(HDHD1)
ACUN113478709(PUDP)
TALA104365725
PADL103924815(HDHD1)
ACHC115334552
AAM106491406(PUDP)
AROW112967788(PUDP)
NPD112948175(PUDP)
DNE112989576(PUDP)
ASN102368298(PUDP)
AMJ102568706(PUDP)
CPOO109306100(PUDP)
GGN109303000(PUDP)
PSS102453212(PUDP)
CMY102946013
CPIC101931055
TST117870303(PUDP)
CABI116830520(PUDP)
MRV120403776
ACS100558667(pudp)
PVT110075577(PUDP)
SUND121921744 121921745 121925501
PBI103063456(PUDP)
PMUR107288362(PUDP)
TSR106547040(PUDP)
PGUT117666491 117673813(PUDP)
VKO123024630 123029895
PMUA114596311(PUDP)
ZVI118081106 118085561(PUDP)
GJA107120295(PUDP) 107122148
XLA108708844 734864(pudp.L)
XTR496806(pudp)
NPR108799144(PUDP)
RTEM120927461
BBUF120994883
BGAR122930573
DRE553642(pudp)
SRX107724265(pudp)
SANH107681515 107691609
SGH107571754 107602763
CCAR109070653(pudp)
CAUA113106481(pudp)
IPU100528229(pudp)
PHYP113537308(pudp)
SMEO124378326
AMEX103021977(pudp)
EEE113576566(pudp)
TRU101066082(pudp)
TNGGSTEN00027076G001
LCO104934756(pudp)
NCC104951994(hdhd1)
CGOB115016622(pudp)
ELY117249767(pudp)
PLEP121962918
SLUC116048606
ECRA117939531(pudp)
PFLV114551172(pudp)
GAT120825874
PPUG119218045
MSAM119913502
CUD121506354
MZE106676213(pudp)
ONL100692478(pudp)
OAU116334043
OML112140222
XMA102236100(pudp)
XCO114141221(pudp)
XHE116716243(pudp)
PRET103477274(pudp)
PFOR103155069(pudp)
PLAI106937984(pudp)
PMEI106906579(pudp)
GAF122826933
CTUL119777019
GMU124861270
NFU107384522(pudp)
KMR108250905
ALIM106533886(pudp)
NWH119429148
AOCE111578406(pudp)
CSEM103389724(pudp)
POV109640050(pudp)
SSEN122765328
HHIP117777961(pudp)
LCF108902576(pudp)
SDU111233033(pudp)
SLAL111670297(pudp)
XGL120797901
HCQ109507803(pudp)
BPEC110156623 110156624
MALB109953020(pudp)
SASA100195978(hdd1a)
OTW112253799
OMY110527507(pudp)
OGO124008745
ONE115133712
SALP111970943(pudp)
SNH120033682
ELS105022507(pudp)
SFM108920447(pudp)
PKI111849081(pudp)
AANG118214210(pudp)
LOC102684227(pudp)
PSPA121320665
ARUT117406622 117973005
LCM102366303(PUDP)
CMK103189014
RTP109933214(pudp)
BFO118428278 118428315
BBEL109477835
CIN100175744
SCLV120332169 120332973
SPU115922677 584312
APLC110983229
SKO100376804 102807036
DMEDmel_CG15441(Gs1l) Dmel_CG31924(CG31924) Dmel_CG5556(CG5556) Dmel_CG5561(CG5561) Dmel_CG5565(CG5565)
DER6540926 6541484 6542226 6542260 6542399
DSE6613349 6617370 6617372 6617373
DSIDsimw501_GD22707(Dsim_GD22707) Dsimw501_GD22912(Dsim_GD22912) Dsimw501_GD22913(Dsim_GD22913) Dsimw501_GD22914(Dsim_GD22914) Dsimw501_GD27240(Dsim_GD27240)
DYADyak_GE14717 Dyak_GE15633 Dyak_GE15644 Dyak_GE15655 Dyak_GE15666
DAN6506658
DSR110183011 110183025 110185616 110185782 110185783 110185854
DPODpse_GA13732 Dpse_GA16569 Dpse_GA18974 Dpse_GA23995 Dpse_GA23996 Dpse_GA25358 Dpse_GA25370 Dpse_GA25376
DPE6595512 6595623 6595626 6595627 6595681 6595682
DMN108161548 108163505 108164113 108164114 108164276 117189030
DWI6641596 6642321 6642322 6642333 6651084
DGR6561812 6562864 6562865
DMODmoj_GI17090 Dmoj_GI17960 Dmoj_GI18114
DAZ108611434 108611952 108611953
DNV108657965 115562156 115562663
DHE111595845 111595848 111599163
DVI6628936
CCAT101453254
BOD106616400 106622018
MDE101898708
SCAC106093756 106095141
LCQ111678144
AGAAgaP_AGAP003372
ACOZ120951201
AARA120908777
AAG5580280
AALB109407473 109419242
CQUCpipJ_CPIJ010605
CPII120415004
CNS116339760 116348748 116348749
AME725653
ACER107993014
ALAB122714076
BIM100742546
BBIF117209641
BVK117233736
BVAN117158646
BTER100642221
BPYO122571339
CCAL108626112
OBB114874630
MGEN117228034
NMEA116426402
CGIG122403743
SOC105198676 105200188
MPHA105834111 105838990
AEC105150358 105153342
ACEP105621489 105627180
PBAR105422786 105425632
VEM105560247 105564231
HST105181783
DQU106750738
CFO105255807 105258469
FEX115234793
LHU105671507 105677565
PGC109853749 109854132
PCF106788605
PFUC122522008
VPS122636576
NVI100113625
CSOL105367953
TPRE106651562 106651563
MDL103569302
CGLO123260806
FAS105262891
DAM107040386
AGIF122859117
CCIN107271741
TCA663851 663913
DPA109535483 109535487 109542521 109542540 109546737 109546738
SOY115878070 115878108 115878110 115883655
ATD109594747 109598318 109598337 109607850
CSET123311089 123311420 123311421 123311966
AGB108905780 108905785 108907446 108910003 108911645
LDC111502196 111512875 111514134 111517140
NVL108558486 108566917
APLN108733417 108733749
PPYR116166565 116171476 116171984
OTU111413936 111414666 111417461 111419456 111419457 111423250 111424008 111424313
BMOR101738730 101743113 101744719
BMAN114243715 114243716 114243960 114250298
MSEX115447300 115447301 115447842 115456234 119191001
DPLKGM_200036 KGM_202413 KGM_204688 KGM_204969
BANY112042793 112047360 112055489 112055496 112058099
PMAC106707833 106715395 106715433 106715445 106721260
PPOT106104204 106104206 106104242 106107080 106111046
PXU106114588 106116595 106116826 106123856
PRAP110993473 110995372 111000723 111004369 111004370
ZCE119828942 119828946 119829124 119830302 119838097
HAW110376592 110376824 110376826 110381123
TNL113492963 113499518 113499519 113502608 113506476
OFU114350788 114356837 114364611 114364639 114364640
PXY105383663 105387443 105393152 105393155 105393156
API100161488 100161759 100168847
DNX107162484 107162485 107162511 107162512
AGS114131430 114131432 114131440 114131442
RMD113548889 113548899 113549873 113549876
BTAB109034409 109034556 109036414 109042372 109043650 109044242
DCI103512259
CLEC106667337 106669721
HHAL106677516 106688904
NLU111046222 111058751
PHUPhum_PHUM075900
FOC113206346
ZNE110839124
CSEC111864874
FCD110856518
DPXDAPPUDRAFT_224443
DMK116916766
PVM113816137 113828884
PJA122255062
HAME121875305
PCLA123757222
PTRU123511744
HAZT108677692
EAF111697203 111711905
ISCIscW_ISCW018756
DSV119435744 119452546 119453706 119453715 119454311 119454313 119454329
RSAN119378723 119397520 119398555 119398568 119398946 119399256 119399321 119399332 119399333 119400631
RMP119179031 119179046 119179050 119179056 119179631 119180392 119185335 119185720 119185961 119187076
VDE111253994
VJA111263657
TUT107362887
DPTE113789437 113791947 113799213 113799640
DFR124490047 124490221 124490243 124495129 124496281 124498127
CSCU111621556
PTEP107456589
SDM118198425
CELCELE_R151.10(R151.10)
CBRCBG_00583 CBG_24156
BMYBM_BM8641(Bm8641) BM_BM9714(Bm9714) BM_BM9715(Bm9715)
LOALOAG_06086 LOAG_06087 LOAG_10378 LOAG_13018
NAINECAME_11348 NECAME_11349 NECAME_11351 NECAME_11352 NECAME_11353
TSPTsp_05737 Tsp_06856 Tsp_10934
HROHELRODRAFT_158659
LGILOTGIDRAFT_198690
PCAN112555956
BGT106066496
GAE121375317
HRF124144041 124144042
HRJ124277296
CRG105323449
MYI110462219 110462220
PMAX117342361 117342926
MMER123554686 123555542
OBI106877710
OSN115209405 115227162
LAK106158430
SMMSmp_042390
SHXMS3_0012851
OVIT265_13675
EGLEGR_07042
NVE5506623
EPA110234181
AMIL114954426
PDAM113685119
SPIS111332547
DGT114524798
XEN124446804
HMG100209702
TADTRIADDRAFT_33235
AQU100639998
QSU111985440 111991255 112011554
MISMICPUN_76552
GSLGasu_00580
CCPCHC_T00009043001
SCEYKL033W-A
AGOAGOS_AGL081W
ERCEcym_7242
KLAKLLA0_F25696g
KMXKLMA_60319
LTHKLTH0D07194g
VPOKpol_380p2
ZROZYRO0B02288g
CGRCAGL0L01969g
NCSNCAS_0A04770(NCAS0A04770)
NDINDAI_0K01820(NDAI0K01820)
TPFTPHA_0G03590(TPHA0G03590)
TBLTBLA_0G02330(TBLA0G02330)
TDLTDEL_0A03200(TDEL0A03200)
TGBHG536_0A04730
KAFKAFR_0B01470(KAFR0B01470)
ZMKHG535_0D04080
PPAPAS_chr3_1148
DHADEHA2G03476g
PICPICST_59029
PGUPGUG_05097
SPAASPAPADRAFT_60620
LELLELG_00585
COTCORT_0A05700
CTENCANTEDRAFT_112156
YLIYALI0F25025g
CLUCLUG_00657
CLUSA9F13_17g00407
CAURCJI97_002432
SLBAWJ20_356
PKZC5L36_0C08150
BNNFOA43_001264
BBRXBRETT_002411
NCRNCU08666
NTENEUTE1DRAFT79833(NEUTE1DRAFT_79833)
SMPSMAC_03751
PANPODANSg2587 PODANSg6120
TTTTHITE_2116026
MTMMYCTH_2299555
CTHRCTHT_0031120
MGRMGG_11115
TMNUCRPA7_7064
SSCKSPSK_07791
FGRFGSG_04189
FPUFPSE_10393
FVRFVEG_10382
FOXFOXG_11438
NHENECHADRAFT_81488
TRETRIREDRAFT_1959 TRIREDRAFT_68444
TRRM419DRAFT_133799 M419DRAFT_31994
MAWMAC_02296 MAC_04261
MAJMAA_02775 MAA_08607
CMTCCM_05654 CCM_08710
PLJVFPFJ_08824
VALVDBG_08375
VDAVDAG_10187
CFJCFIO01_05651
SAPOSAPIO_CDS6913
ELAUCREL1_2661 UCREL1_4142 UCREL1_5461
PFYPFICI_14577
SSLSS1G_05718 SS1G_14053
BFUBCIN_05g00510 BCIN_12g02960
MBEMBM_03250 MBM_05068
PSCOLY89DRAFT_668373 LY89DRAFT_697498 LY89DRAFT_709830
GLZGLAREA_09479 GLAREA_09644 GLAREA_12462
ANIAN9497.2
AFMAFUA_3G03460 AFUA_6G10760
ACTACLA_084490
NFINFIA_005640 NFIA_056530
AORAO090023000196
ANGANI_1_1332094(An11g10240) ANI_1_1572094(An11g00640)
AFVAFLA_003174 AFLA_006557
ALUCAKAW2_80064A
ACHEACHE_60165S
APUUAPUU_51354A
PCSPc22g13090
PDPPDIP_39030
TMFPMAA_035490
TRGTRUGW13939_05262
CIMCIMG_09666
CPWCPC735_023710
UREUREG_02228 UREG_04605
PBLPAAG_05134
PBNPADG_04977
ABEARB_00780 ARB_02772
TVETRV_07692 TRV_07781
AJEHCAG_04957 HCAG_06681
BGHBDBG_07916
PNOSNOG_14964
PTEPTT_09439 PTT_15961
BZECOCCADRAFT_34701 COCCADRAFT_40638
BSCCOCSADRAFT_146665 COCSADRAFT_39251
BORCOCMIDRAFT_10139 COCMIDRAFT_35495 COCMIDRAFT_37417 COCMIDRAFT_4486
AALTCC77DRAFT_1025551 CC77DRAFT_1039659
ZTRMYCGRDRAFT_101702 MYCGRDRAFT_75784
PFJMYCFIDRAFT_144184
BCOMBAUCODRAFT_307814
NPAUCRNP2_4926
TMLGSTUM_00010863001
SPOSPAC4C5.01 SPCC1020.07
CNECNC04170 CNF00655
CNBCNBC3020 CNBF4020
CGICGB_C6270W CGB_F5610W
TMSTREMEDRAFT_28847
TASAA1Q1_06092
TVSTRAVEDRAFT_141963
DSQDICSQDRAFT_133066
SHSSTEHIDRAFT_67030
HIRHETIRDRAFT_320687
PSQPUNSTDRAFT_42683
ADLAURDEDRAFT_111156
FMEFOMMEDRAFT_156002
GTRGLOTRDRAFT_49832
LBCLACBIDRAFT_189155
MPRMPER_10520
MRRMoror_13091
CCICC1G_03265
SCMSCHCODRAFT_16727
ABPAGABI1DRAFT112363(AGABI1DRAFT_112363)
ABVAGABI2DRAFT192327(AGABI2DRAFT_192327)
CPUTCONPUDRAFT_101256
SLASERLADRAFT_465297
WSEWALSEDRAFT_68658
WICJ056_004604
UMAUMAG_05286
PFPPFL1_05435
MGLMGL_2860
MRTMRET_3454
MSYMMSY001_0344
PGRPGTG_16637
MLRMELLADRAFT_53667
EHIEHI_074120(79.t00019) EHI_088460(281.t00004) EHI_178660(15.t00060)
EDIEDI_083970 EDI_128750 EDI_135540
EIVEIN_065880 EIN_081730 EIN_504330
ACANACA1_126710 ACA1_175890 ACA1_207330
SMINv1.2.031638.t1(symbB.v1.2.031638.t1)
PTIPHATRDRAFT_35659
FCYFRACYDRAFT_189181
AAFAURANDRAFT_14688
PIFPITG_11164
SPARSPRG_03079 SPRG_15429
TVATVAG_005730 TVAG_007160 TVAG_023520 TVAG_110720 TVAG_117360 TVAG_133450 TVAG_133950 TVAG_145590 TVAG_372950 TVAG_398770 TVAG_417190 TVAG_440810 TVAG_481930 TVAG_488000 TVAG_547260
PSYRN018_25250
PSPPSPPH_5085
PAMGBKM19_028955
PCIPCH70_50530
PAVLBKM03_29040
PFLPFL_1849
PPRCPFLCHA0_c18800
PPROPPC_1893
PFEPSF113_4068
PFNHZ99_08720
PFOPfl01_1752
PFSPFLU_4647
PPZH045_14105
PFBVO64_4894
PMANOU5_5374
PTVAA957_21600
PCGAXG94_06785
PVRPverR02_23615
PAZOAYR47_30005
POIBOP93_19265
PFWPF1751_v1c41540
PFFPFLUOLIPICF715405
PFXA7318_19920
PBAPSEBR_a3970
PBCCD58_20955
PPUUPputUW4_03670
PSKU771_17505 U771_24155
PCHEY04_08870
PCZPCL1606_41900
PCPJM49_20975
PFZAV641_14285
PRHLT40_19640
PSESPSCI_1887
PSEMTO66_09485
PPSYAOC04_10930
PSOSPOS17_1856
PKRAYO71_11700
PFKPFAS1_20465
PANRA7J50_4346
PSILPMA3_20545
PADEC3B55_00863
PKEDLD99_09600
PUMHGP31_22930
PGYAWU82_01725
PVKEPZ47_20120
PBZGN234_27325
PATAJWU58_18580
PZEHU754_010345
PMOEHV782_009935
PSEPC4K39_1926
PTZHU718_010035
PSHHHU773_020200
PHVHU739_008825
PAZEKSS91_19910
PALVKSS97_09430
PZAHU749_020875
PIEHU724_009510
BLEPAL038_04970
PARABTO02_05860
SYDSyncc9605_1138
SYESyncc9902_1319
SYGsync_1552
SYRSynRCC307_1346
SYXSynWH7803_1039
SYNKKR100_08050
SYNRKR49_03235
SYNDKR52_10945
SYHSyncc8109_1550
SYNWSynWH8103_01142
SYNCCB0101_03625
SYWSYNW1012
CGCCyagr_0416
CYICBM981_0714
PMMPMM1380
PMTPMT_0391
PMNPMN2A_0056
PMCP9515_15581
PMFP9303_18961
PMENATL1_06771
PRMEW15_0719
CHONNIES4102_05570
TERTery_0680
ARPNIES39_B00780
PAGHNIES204_06060
LFSHFV01_07165
CERRGRSB_0656
RBARB10370
PSLPsta_4600
PIRVN12_13805
MFFMFFC18_28720
LCREPla8534_59730
BVOPan97_40150
TTFTHTE_3960
AMUCPan181_34080
PLONPla110_25970
 » show all
Reference
1  [PMID:20722631]
  Authors
Preumont A, Rzem R, Vertommen D, Van Schaftingen E
  Title
HDHD1, which is often deleted in X-linked ichthyosis, encodes a pseudouridine-5'-phosphatase.
  Journal
Biochem J 431:237-44 (2010)
DOI:10.1042/BJ20100174
  Sequence
[hsa:8226]
Other DBs
ExplorEnz - The Enzyme Database: 3.1.3.96
IUBMB Enzyme Nomenclature: 3.1.3.96
ExPASy - ENZYME nomenclature database: 3.1.3.96
BRENDA, the Enzyme Database: 3.1.3.96

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