KEGG   ENZYME: 3.1.4.2
Entry
EC 3.1.4.2                  Enzyme                                 
Name
glycerophosphocholine phosphodiesterase;
glycerophosphinicocholine diesterase;
glycerylphosphorylcholinediesterase;
sn-glycero-3-phosphorylcholine diesterase;
glycerolphosphorylcholine phosphodiesterase;
glycerophosphohydrolase
Class
Hydrolases;
Acting on ester bonds;
Phosphoric-diester hydrolases
Sysname
sn-glycero-3-phosphocholine glycerophosphohydrolase
Reaction(IUBMB)
sn-glycero-3-phosphocholine + H2O = choline + sn-glycerol 3-phosphate [RN:R01030]
Reaction(KEGG)
R01030;
(other) R01470
Substrate
sn-glycero-3-phosphocholine [CPD:C00670];
H2O [CPD:C00001]
Product
choline [CPD:C00114];
sn-glycerol 3-phosphate [CPD:C00093]
Comment
Also acts on sn-glycero-3-phosphoethanolamine.
History
EC 3.1.4.2 created 1961, modified 1976
Pathway
ec00564  Glycerophospholipid metabolism
Orthology
K18695  glycerophosphocholine phosphodiesterase GPCPD1
Genes
HSA56261(GPCPD1)
PTR458085(GPCPD1)
PPS100992325(GPCPD1)
GGO101144579(GPCPD1)
PON100457313(GPCPD1)
NLE100585965(GPCPD1)
MCC719117(GPCPD1)
MCF102119326(GPCPD1)
CSAB103246868(GPCPD1)
CATY105582107(GPCPD1)
PANU101019332(GPCPD1)
TGE112632971(GPCPD1)
RRO104674573(GPCPD1)
RBB108533306
TFN117068491(GPCPD1)
PTEH111546467(GPCPD1)
CJC100403898(GPCPD1)
SBQ101052158(GPCPD1)
CSYR103265018(GPCPD1)
MMUR105865955(GPCPD1)
OGA100942596(GPCPD1)
MMU74182(Gpcpd1)
MCAL110312472(Gpcpd1)
MPAH110318489(Gpcpd1)
RNO362219(Gpcpd1)
MCOC116090982(Gpcpd1)
MUN110557046(Gpcpd1)
CGE100772527(Gpcpd1)
PLEU114699529(Gpcpd1)
HGL101716686(Gpcpd1)
CPOC100713039(Gpcpd1)
CCAN109695566(Gpcpd1)
DORD105981656(Gpcpd1)
DSP122120176(Gpcpd1)
OCU100340388(GPCPD1)
OPI101522744(GPCPD1)
TUP102476992(GPCPD1)
CFA485778(GPCPD1)
VVP112930064(GPCPD1)
VLG121477797(GPCPD1) 121488974
AML100464203(GPCPD1)
UMR103674412(GPCPD1)
UAH113258363(GPCPD1)
UAR123799580(GPCPD1)
ELK111141391
LLV125108477
MPUF101692701(GPCPD1)
ORO101373799(GPCPD1)
EJU114216418(GPCPD1)
ZCA113937202(GPCPD1)
MLX118011263(GPCPD1)
FCA101081213(GPCPD1)
PYU121012460(GPCPD1)
PBG122496544(GPCPD1)
PTG102966968(GPCPD1)
PPAD109274735(GPCPD1)
AJU106980167(GPCPD1)
HHV120225824(GPCPD1)
BTA518469(GPCPD1)
BOM102271682(GPCPD1)
BIU109567633(GPCPD1)
BBUB102408701(GPCPD1)
CHX102172822(GPCPD1)
OAS101115143(GPCPD1)
ODA120868923(GPCPD1)
CCAD122447808(GPCPD1)
SSC100152321(GPCPD1)
CFR102516881(GPCPD1)
CBAI105083009(GPCPD1)
CDK105101383(GPCPD1)
VPC102526551(GPCPD1)
BACU103000701(GPCPD1)
LVE103090265(GPCPD1)
OOR101289006(GPCPD1)
DLE111165654(GPCPD1)
PCAD102976465(GPCPD1)
PSIU116740289(GPCPD1)
ECB100051946(GPCPD1)
EPZ103559713(GPCPD1)
EAI106823173(GPCPD1)
MYB102244847(GPCPD1)
MYD102752720 102768123(GPCPD1)
MMYO118654251 118662987(GPCPD1)
MLF102419527(GPCPD1)
MNA107536381(GPCPD1)
PKL118708491(GPCPD1)
HAI109383836(GPCPD1)
DRO112304233(GPCPD1)
SHON118990886(GPCPD1)
AJM119051146(GPCPD1)
PDIC114507095(GPCPD1)
PHAS123815175(GPCPD1)
MMF118618266(GPCPD1)
RFQ117015623(GPCPD1)
PALE102889103(GPCPD1)
PGIG120603420(GPCPD1)
PVP105298656(GPCPD1)
RAY107499046(GPCPD1)
MJV108392437(GPCPD1)
TOD119232779(GPCPD1)
SARA101549384(GPCPD1)
LAV100661261(GPCPD1)
TMU101350480
DNM101429276(GPCPD1)
MDO100033295(GPCPD1)
GAS123236893(GPCPD1)
SHR100923561(GPCPD1)
PCW110207658(GPCPD1)
OAA100083805(GPCPD1)
GGA421311(GPCPD1)
PCOC116231205(GPCPD1)
MGP100543090(GPCPD1)
CJO107310902(GPCPD1)
NMEL110395459(GPCPD1)
APLA101795969(GPCPD1)
ACYG106045601(GPCPD1)
AFUL116488172(GPCPD1)
TGU100218511(GPCPD1)
LSR110474855(GPCPD1)
SCAN103821340(GPCPD1)
PMOA120506814(GPCPD1)
OTC121335802(GPCPD1)
PRUF121358634(GPCPD1)
GFR102037405(GPCPD1)
FAB101809898(GPCPD1)
PHI102106750(GPCPD1)
PMAJ107201576(GPCPD1)
CCAE111926646(GPCPD1)
CCW104696625(GPCPD1)
ETL114069820(GPCPD1)
ZAB102072423(GPCPD1)
FPG101911738(GPCPD1)
FCH102047465(GPCPD1)
CLV102085356(GPCPD1)
EGZ104130157(GPCPD1)
NNI104014927(GPCPD1)
ACUN113477801(GPCPD1)
TALA116964169(GPCPD1)
PADL103919568(GPCPD1)
ACHC115344250(GPCPD1)
AAM106499795(GPCPD1)
AROW112973151(GPCPD1)
NPD112942911(GPCPD1)
DNE112989338(GPCPD1)
ASN102375902(GPCPD1)
AMJ102563733(GPCPD1)
CPOO109319474(GPCPD1)
GGN109296697(GPCPD1)
PSS102452347(GPCPD1)
CMY102937446(GPCPD1)
CPIC101936233(GPCPD1)
TST117874204(GPCPD1)
CABI116824047(GPCPD1)
MRV120400178(GPCPD1)
ACS100554925(gpcpd1)
PVT110078954(GPCPD1)
SUND121921029(GPCPD1)
PBI103049142(GPCPD1)
PMUR107287452(GPCPD1)
TSR106553523(GPCPD1)
PGUT117674343(GPCPD1)
VKO123030312(GPCPD1)
PMUA114593646(GPCPD1)
ZVI118082507(GPCPD1)
GJA107107082(GPCPD1)
XLA108717755(gpcpd1.S) 735213(gpcpd1.L)
XTR100216176(gpcpd1)
NPR108795467(GPCPD1)
RTEM120938026(GPCPD1)
BBUF120998888(GPCPD1)
BGAR122934402(GPCPD1)
DRE492483(gpcpd1)
SRX107742708 107756671
SANH107697181
SGH107593247 107600082
CCAR109050125 109074258
CAUA113073668 113092558 113120472
IPU108257980(gpcpd1)
PHYP113545179(gpcpd1)
SMEO124376978(gpcpd1)
AMEX103023293(gpcpd1)
EEE113590126(gpcpd1)
TRU101064928(gpcpd1)
TNGGSTEN00020271G001
LCO104920852(gpcpd1)
NCC104947581(gpcpd1)
CGOB115028864(gpcpd1)
ELY117270643(gpcpd1)
PLEP121955275(gpcpd1)
SLUC116041931(gpcpd1)
ECRA117961880(gpcpd1)
PFLV114572945(gpcpd1)
GAT120808384(gpcpd1)
PPUG119194709(gpcpd1)
MSAM119908492(gpcpd1)
CUD121521201(gpcpd1)
MZE101468338(gpcpd1)
ONL100707161(gpcpd1)
OAU116332213(gpcpd1)
OLA101160778(gpcpd1)
OML112158022(gpcpd1)
XMA102224753(gpcpd1)
XCO114158454(gpcpd1)
XHE116733987(gpcpd1)
PRET103457864(gpcpd1)
PFOR103148039(gpcpd1)
PLAI106946442(gpcpd1)
PMEI106929200(gpcpd1)
GAF122825015(gpcpd1)
CVG107097542(gpcpd1)
CTUL119784117(gpcpd1)
GMU124881878(gpcpd1)
NFU107378119(gpcpd1)
KMR108231836(gpcpd1)
ALIM106518546(gpcpd1)
NWH119418471(gpcpd1)
AOCE111569672(gpcpd1)
CSEM103381050(gpcpd1)
POV109632383(gpcpd1)
SSEN122783978(gpcpd1)
HHIP117758229(gpcpd1)
LCF108896917(gpcpd1)
SDU111239486(gpcpd1)
SLAL111672778(gpcpd1)
XGL120788804(gpcpd1)
HCQ109507215(gpcpd1)
BPEC110168258(gpcpd1)
MALB109962217(gpcpd1)
SASA106571744 106608056
OTW112217816 112250575
OMY110522444 110529876(gpcpd1)
OGO123991001 123995276
ONE115108001(gpcpd1) 115139221
SALP111954649 112074500
SNH120019106(gpcpd1) 120024034
ELS105017514(gpcpd1)
SFM108929397(gpcpd1)
PKI111837604(gpcpd1)
AANG118229954(gpcpd1)
LOC102683496(gpcpd1)
PSPA121315940 121317062
ARUT117403129 117411053
LCM102367204(GPCPD1)
CMK103181646(gpcpd1)
RTP109923471(gpcpd1)
BFO118420929
BBEL109466177
CIN100183868
SCLV120337795 120342627
SPU594641
SKO100370219
DMEDmel_CG2818(CG2818)
DER6542896
DSE6613279
DSIDsimw501_GD23248(Dsim_GD23248)
DYADyak_GE18251
DAN6498062
DSR110178121
DPODpse_GA15473 Dpse_GA17792
DPE6589046 6591582
DMN108157720 108162983
DWI6642274 6647701
DGR6566784
DMODmoj_GI14466 Dmoj_GI23897
DAZ108610002 108612117
DNV108649745 115562108
DHE111595869 111601922
DVI6627721
CCAT101451344
BOD106620031
MDE101888955 101897749
SCAC106086462 106093448
LCQ111675154 111690423
ACOZ120957125
AARA120900357
AAG5564200
AALB109427939 109428257
CQUCpipJ_CPIJ009059
CPII120414647
CNS116340808
AME410117
ACER107998176
ALAB122712378
BIM100749468
BBIF117210622
BVK117237471
BVAN117164087
BTER100645227
BPYO122565812
CCAL108622100
OBB114874953
MGEN117218680
NMEA116435247
CGIG122398134
SOC105197583
MPHA105837893
AEC105149901
ACEP105627339
PBAR105432811
VEM105562446
HST105186802
DQU106747817
CFO105250928
FEX115243420
LHU105674904
PGC109858983
OBO105281516
PCF106789265
PFUC122514283
VPS122634924
NVI100118232
CSOL105369048
TPRE106650168
MDL103575478
CGLO123272750
FAS105266185
DAM107039166
AGIF122856737
CCIN107274174
TCA662257
DPA109538548
SOY115880662
ATD109601749
CSET123310962
AGB108904758
LDC111512440
NVL108559381
APLN108732534
PPYR116171193
OTU111414033
BMOR101743990
BMAN114245519
MSEX115440996
DPLKGM_214218
BANY112058257
PMAC106714445
PPOT106099662
PXU106127637
PRAP110999094
ZCE119830561
HAW110375482
TNL113500995
OFU114364713
PXY105398594
API100159211
DNX107166899
AGS114126205
RMD113559632
BTAB109031275
DCI103511955
CLEC106672797
HHAL106684327
NLU111055517
PHUPhum_PHUM249710
FOC113210381
ZNE110832935
CSEC111866397
FCD110846680
DPXDAPPUDRAFT_307611
DMK116934144
PVM113808219
PJA122259563
HAME121863753
PCLA123757268
PTRU123504100
HAZT108679733
EAF111701033
ISCIscW_ISCW006797
DSV119437428
RSAN119389923
RMP119160977
VDE111250093
VJA111272083
TUT107371100
DPTE113792484 113795557
DFR124495407 124500122
CSCU111641727
PTEP107451427
SDM118181448
CELCELE_K10B3.6(gpcp-1) CELE_T05H10.7(gpcp-2)
CBRCBG_13338 CBG_14135
BMYBM_BM5605(Bma-gpcp-2.1)
LOALOAG_02221
TSPTsp_08442
LGILOTGIDRAFT_132728
PCAN112562577
BGT106066638 106071052
GAE121382877 121383736
HRF124139276
HRJ124275920
CRG105336617
MYI110441956
MMER123551895 123552075
OBI106879322
OSN115217981
LAK106168463
SMMSmp_054800 Smp_162910
SHXMS3_0011725
OVIT265_02264 T265_14041
EGLEGR_05839
NVE116610300
ATEN116304130
DGT114519105
TADTRIADDRAFT_53182
GSLGasu_57030
CMTCCM_08480
PSCOLY89DRAFT_773861
SLASERLADRAFT_460326
TVATVAG_058410 TVAG_330620
 » show all
Reference
1  [PMID:13315235]
  Authors
DAWSON RM.
  Title
Liver glycerylphosphorylcholine diesterase.
  Journal
Biochem J 62:689-93 (1956)
DOI:10.1042/bj0620689
Reference
2  [PMID:13143024]
  Authors
HAYAISHI O, KORNBERG A.
  Title
Metabolism of phospholipides by bacterial enzymes.
  Journal
J Biol Chem 206:647-63 (1954)
Reference
3  [PMID:13403918]
  Authors
WEBSTER GR, MARPLES EA, THOMPSON RH.
  Title
Glycerylphosphorylcholine diesterase activity of nervous tissue.
  Journal
Biochem J 65:374-7 (1957)
DOI:10.1042/bj0650374
Other DBs
ExplorEnz - The Enzyme Database: 3.1.4.2
IUBMB Enzyme Nomenclature: 3.1.4.2
ExPASy - ENZYME nomenclature database: 3.1.4.2
BRENDA, the Enzyme Database: 3.1.4.2
CAS: 9025-85-8

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