Entry |
|
Name |
phospholipase D;
lipophosphodiesterase II;
lecithinase D;
choline phosphatase
|
Class |
Hydrolases;
Acting on ester bonds;
Phosphoric-diester hydrolases
 |
Sysname |
phosphatidylcholine phosphatidohydrolase
|
Reaction(IUBMB) |
a phosphatidylcholine + H2O = choline + a phosphatidate [RN: R01310]
|
Reaction(KEGG) |
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Substrate |
|
Product |
|
Comment |
Also acts on other phosphatidyl esters.
|
History |
EC 3.1.4.4 created 1961
|
Pathway |
ec00564 | Glycerophospholipid metabolism |
ec01110 | Biosynthesis of secondary metabolites |
|
Orthology |
|
Genes |
» show all
 |
Reference |
|
Authors |
Astrachan L. |
Title |
The bond hydrolyzed by cardiolipin-specific phospholipase D. |
Journal |
|
Reference |
|
Authors |
EINSET E, CLARK WL. |
Title |
The enzymatically catalyzed release of choline from lecithin. |
Journal |
J Biol Chem 231:703-15 (1958) |
Reference |
|
Authors |
HANAHAN DJ, CHAIKOFF IL |
Title |
On the nature of the phosphorus-containing lipides of cabbage leaves and their relation to a phospholipide-splitting enzyme contained in these leaves. |
Journal |
J Biol Chem 172:191-8 (1948) |
Reference |
|
Authors |
TOOKEY HL, BALLS AK. |
Title |
Plant phospholipase D. I. Studies on cottonseed and cabbage phospholipase D. |
Journal |
J Biol Chem 218:213-24 (1956) |
Other DBs |
ExplorEnz - The Enzyme Database: | 3.1.4.4 |
ExPASy - ENZYME nomenclature database: | 3.1.4.4 |
BRENDA, the Enzyme Database: | 3.1.4.4 |
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