KEGG   ENZYME: 3.1.4.59
Entry
EC 3.1.4.59                 Enzyme                                 
Name
cyclic-di-AMP phosphodiesterase;
gdpP (gene name)
Class
Hydrolases;
Acting on ester bonds;
Phosphoric-diester hydrolases
Sysname
cyclic bis(3'->5')diadenylate 3'-adenylylhydrolase
Reaction(IUBMB)
cyclic di-3',5'-adenylate + H2O = 5'-O-phosphonoadenylyl-(3'->5')-adenosine [RN:R12345]
Reaction(KEGG)
R12345
Substrate
cyclic di-3',5'-adenylate [CPD:C20565];
H2O [CPD:C00001]
Product
5'-O-phosphonoadenylyl-(3'->5')-adenosine [CPD:C22092]
Comment
The enzyme, described from Gram-positive bacteria, degrades the second messenger cyclic di-3',5'-adenylate. It is a membrane-bound protein that contains a cytoplasmic facing Per-Arnt-Sim (PAS) domain, a modified GGDEF domain, and a DHH/DHHA1 domain, which confers the phosphodiesterase activity. Activity requires Mn2+ and is inhibited by pApA.
History
EC 3.1.4.59 created 2019
Orthology
K22927  cyclic-di-AMP phosphodiesterase
Genes
SDOSD1155_04175
BSUBSU40510(yybT)
BSRI33_4225
BSLA7A1_1248
BSHBSU6051_40510(yybT)
BSYI653_19910
BSUTBSUB_04302(gdpP)
BSULBSUA_04302(gdpP)
BSUSQ433_22355
BSOBSNT_10769(yybT)
BSNBSn5_11285
BSQB657_40510(cdnD)
BSXC663_3970(yybT)
BSPU712_20525
BSSBSUW23_20215(yybT)
BSTGYO_4469
BLIBL00093(yybT)
BLDBLi04354(yybT)
BLHBaLi_c43360(yybT)
BAYRBAM_037590
BAQBACAU_3766(yybT)
BYABANAU_3936(ybbT)
BAMPB938_19260
BQYMUS_4449(yybT)
BAMLBAM5036_3676(cdnD)
BAMARBAU_3879(cdnD)
BAMNBASU_3664(cdnD)
BAMBBAPNAU_3945(yybT)
BAMTAJ82_21205
BAMYV529_40210
BMPNG74_03936(nrnA_2)
BAOBAMF_3873(yybT)
BAZBAMTA208_20430(yybT)
BQLLL3_04201(yybT)
BXHBAXH7_04190(yybT)
BAMIKSO_000285
BAMCU471_39150
BAMFU722_19985
BSIACWD84_00440
BAEBATR1942_18350
BVMB9C48_19185
BSONS101395_05054
BHTDIC78_10655
BMOJHC660_39680(gdpP)
BTEQG4P54_20725(gdpP)
BIQAN935_20640
BANBA_5719
BARGBAA_5719
BATBAS5323
BAHBAMEG_5771
BAIBAA_5754
BAXH9401_5462
BANTA16_57390
BANRA16R_58090
BANSBAPAT_5486
BANHHYU01_27940
BANVDJ46_4370
BCEBC5472
BCABCE_5621
BCZBCE33L5167
BCRBCAH187_A5658
BCBBCB4264_A5597
BCUBCAH820_5580
BCGBCG9842_B5338
BCQBCQ_5320
BCXBCA_5625
BALBACI_c54760
BNCBCN_5397
BCFbcf_27480
BCERBCK_07940
BCEFBcrFT9_04406
BCYBcer98_4010
BTKBT9727_5151
BTLBALH_4977
BTBBMB171_C5070
BTTHD73_5887
BTHRYBT1520_29175
BTHIBTK_29070
BTCCT43_CH5511
BTFYBT020_27295
BTMMC28_4702
BTGBTB_c56720
BTIBTG_20970
BTNBTF1_25960
BTHTH175_ch5604
BTHUYBT1518_30710
BTWBF38_1194
BTHYAQ980_01905
BWEBcerKBAB4_5263
BWWbwei_4302(yybT)
BMYOBG05_533
BTYBtoyo_2669
BMYCDJ92_2565
BBYCY96_26490
BWDCT694_29375
BTROFJR70_21540
BMOBMLA2C4_28390
BNTGSN03_26210
BPACLMD38_26365
BPUBPUM_3706
BPUMBW16_19710
BPUSUP12_19030
BJSMY9_4192
BACIB1NLA3E_22180
BIFN288_25915
BMETBMMGA3_16650(yybT)
GSTHW35_09855
BACWQR42_18540
BACPSB24_09990
BACBOY17_02465
BACOOXB_0950
BACYQF06_18735
BACLBS34A_43850(nrnA_2)
BALMBsLM_4104
BSMBSM4216_3840
BGYBGLY_4715
BWHA9C19_20085
BXIBK049_08445
BALTCFN77_19590
BACSAUL54_11040
BSAFBSL056_20155
BITBIS30_10125
BACQDOE78_24615
BFDNCTC4823_00040(yybT)
BDAFSZ17_23110
BSHILGQ02_21100
BBADK7T73_19800
BCOBcell_4311
BHKB4U37_21500
BCOHBC6307_22885
BCIRC2I06_18590
BMQBMQ_5265
BMDBMD_5253
BMHBMWSH_0020(yybT)
BMEGBG04_2257
BEOBEH_24030
BFXBC359_01085
PKSIE339_23545
BCKBCO26_2952(yybT)
BAGBcoa_1307
BCOABF29_2247
BHABH4031
BCLABC4103
BLEBleG1_3977
BKWBkAM31D_25265(nrnA_2)
BGIBGM20_14540
BPFBpOF4_07850
BONA361_27065
BKOCKF48_10945
CGOTJ1899_22065
OIHOB3462
OCNCUC15_19810
GKAGK3478
GTEGTCCBUS3UF5_38950
GTKGT3570_17050
GTMGT3921_01575
GLIGLN3_10080
GTNGTNG_3419
GWCGWCH70_3413
GYCGYMC61_3542
GYAGYMC52_3576
GCTGC56T3_3460
GMCGY4MC1_3820
GGHGHH_c35680(yybT)
GJFM493_18275
GEAGARCT_03462(nrnA_2)
GSEGT50_09170
GSRGS3922_15865
GZAIC807_13380
GTHGeoth_3929
PTLAOT13_03175
PTBDER53_04535
PCALBV455_01806(nrnA_1)
AFLAflv_2844
AGNAFK25_14570
ANMGFC28_2712
AAMYGFC30_226
ANLGFC29_2722
ANDGRQ40_18145
ACAIISX45_15520
ASEDIRT44_05080
AXLAXY_23870
LSPBsph_4765
LGYT479_23590
LFUHR49_00195
LYSLBYS11_22905
LYBC3943_26965
LYZDCE79_18295
LYGC1N55_20305
LPAKGDS87_24215
LAGRFJQ98_26360
LMACI6G82_18990
HHDHBHAL_5131(yybT)
HMNHM131_01360
HLIHLI_12180
TAPGZ22_11875
TAIDKS242_17270
VIRX953_19660
VHLBME96_18760
VIGBKP57_10360
VILCFK37_06285
VNECFK40_01775
VPNA21D_01496(nrnA_1)
VIMGWK91_13040
VPTKBP50_21810
LAOAOX59_13855
FPNABE65_021215
FARABE41_020270
SJEAAV35_000190
APAKAP3564_04765
BSJUP17_24945
BMURABE28_023710
PBUTDTO10_11620
PASABAOM_5106
PPSRI6J18_14570
AQTFN924_18635
BTHVCQJ30_18950
PSYHD0S48_12425
PSYOPB01_20725
PRDF7984_18770
GRCGI584_23610
RUEDT065_10890
SALEEPH95_11180
SCIBHUG20_18845
SCIAHUG15_22550
POFGS400_19875
NMKCHR53_28030
NTMBTDUT50_01845
MEKUHUW50_09085
MSEMGMB29_26740
MDGK8L98_24745
AIAAWH56_007015
BLENNCTC4824_04273(yybT)
SEDDERJ70_18920
BVQFHE72_23275
RMFD5E69_22470
BVJI5776_21215
BOUI5818_25820
CTHUHUR95_02280
BBEVBBEV_0024
BSEBsel_3307
MCUIG8O30_13550
GAJMY490_21935
STEAC0679_15545
SAUSA0013
SAVSAV0014
SAWSAHV_0014
SAHSaurJH1_0014
SAJSaurJH9_0014
SAMMW0014
SASSAS0014
SARSAR0014
SACSACOL0014
SAXUSA300HOU_0014
SAASAUSA300_0014
SAOSAOUHSC_00015
SAENWMN_0013
SADSAAV_0016
SUUM013TW_0015(gdpP)
SUVSAVC_00070
SUESAOV_0014
SUJSAA6159_00014
SUKSAA6008_00014
SUCECTR2_14
SUTSAT0131_00016
SUQHMPREF0772_10454
SUZMS7_0014
SUDST398NM01_0014
SUXSAEMRSA15_00140
SUWSATW20_00140
SUGSAPIG0014
SUFSARLGA251_00140
SAUASAAG_00554
SAUERSAU_000014
SAUNSAKOR_00014
SAUSSA40_0015
SAUUSA957_0015
SAUGSA268_0015
SAUZSAZ172_0014
SAUTSAI1T1_2000120
SAUJSAI2T2_1000120
SAUKSAI3T3_1000120
SAUQSAI4T8_1000120
SAUVSAI7S6_1000120
SAUWSAI5S5_1000120
SAUXSAI6T6_1000120
SAUYSAI8T7_1000120
SAUFX998_0014
SABSAB0014
SUYSA2981_0014
SAUBC248_0014
SAUMBN843_120
SAUCCA347_14
SAURSABB_02135
SAUIAZ30_00070
SAUDCH52_05380
SAMSNI36_00075
SUHSAMSHR1132_00140
SERSERP2539
SEPSE_0013
SEPPSEB_00014
SEPSDP17_1385
SHASH0013
SHHShL2_00013
SSPSSP0014
SCASCA_2462
SLGSLGD_02559
SLNSLUG_00130
SSDSPSINT_2438
SDTSPSE_0016
SDPNCTC12225_00017
SWAA284_00075
SPASSTP1_1384
SXYBE24_12415
SXLSXYLSMQ121_0014
SXOSXYL_00014
SHUSHYC_00135
SCAPAYP1020_2050(nrnA_2)
SSCHLH95_00080
SSCZRN70_00080
SAGQEP23_09940
SEQOSE1039_26670
SSIFAL483_09915
SCVA4G25_07885
SPETCEP67_08575
SLZB5P37_05895
SCOHBZ166_04520
SNLBJD96_00070
SKLC7J89_01540
SFQC7J90_03050
SHOMEGX58_04435
SMUSC7J88_07260
SCARDWB96_00070
SCHRDWB92_00075
SARLSAP2_00160
SPICSAMEA4384060_0018
SSHNCTC13712_00016
SSIMSAMEA4384339_0016
SDBCNQ82_01080
SLLOISP08_00075
SAULI6G39_00550
SSACI6I31_04275
SSCUCEP64_12640
SFFFOB90_07730
SSTESAMEA4384403_0026
MLENH3V22_09290
MVTI6J10_10965
MCLMCCL_0016
MCAKMCCS_00180(nrnA_1)
MACRBHM04_10610
MBOEHT586_00085
MARYLAU42_00085
SHVAAT16_00255
SBACBVH56_08925
JEAJEM45_07545
NAMPKPF49_00065
LMOlmo0052
LMNLM5578_2964
LMYLM5923_2913
LMTLMRG_02481
LMOCLMOSLCC5850_0052
LMOEBN418_0055
LMOBBN419_0056
LMODLMON_0053
LMOWAX10_08735
LMOQLM6179_0331(cdnD)
LMRLMR479A_0059(cdnD)
LMOMIJ09_10115
LMFLMOf2365_0061
LMCLm4b_00061
LMOGBN389_00620(yybT)
LMPMUO_00310
LMOLLMOL312_0060
LMOJLM220_16517
LMOZLM1816_03777(pdeA)
LMOXAX24_12800
LMHLMHCC_2618
LMQLMM7_0046(yybT)
LMLlmo4a_0045
LMGLMKG_02277
LMSLMLG_0115
LMJLMOG_01570
LMWLMOSLCC2755_0057
LMXLMOSLCC2372_0052
LMZLMOSLCC2482_0057
LMONLMOSLCC2376_0049
LMOSLMOSLCC7179_0058
LMOOLMOSLCC2378_0062
LMOYLMOSLCC2479_0052
LMOTLMOSLCC2540_0058
LMOALMOATCC19117_0060
LMOKCQ02_00315
LMVY193_00985(pdeA)
LINlin0045
LWElwe0043
LSGlse_0041
LIVLIV_0050
LIIJL52_00500
LIWAX25_00510
LIAJL58_00440
LIOJL53_00440
LWIUE46_15575
LGZNCTC10812_00036
LMARLAX80_000255(pdeA)
BTHSCNY62_05770
ESIExig_3035
EATEAT1b_1748
EANEab7_2839
EXMU719_16465
EXUESP131_02115
EAPKB235_01600
EACEKKI46_16365
GOTAXE85_07780
GMONCTC11323_01521
GEQCG018_01380
GSAFOC50_02990
GHANCTC10459_01552(nrnA_2)
BBEBBR47_59200(yybT)
BLRBRLA_c046400(nrnA_2)
BFMBP422_25010
BAGRBA6348_03130
BRWGOP56_15790
BCHSJNE38_30345
BCOPJD108_21970
PJDPjdr2_6261
GYMGYMC10_6307
PPYPPE_04922
PPMPPSC2_25370(yybT)
PPOPPM_5042(yybT)
PPOLX809_42010
PPQPPSQR21_051440
PPOYRE92_11840
PMSKNP414_07950
PMQPM3016_7464
PMWB2K_37635
PTAHPL003_07330
PLVERIC2_c01520
PSABPSAB_24075
PDUPDUR_27700
PBDPBOR_36040
PGMPGRAT_32380
PODPODO_30455
PAENP40081_37370
PAEFR50345_30670
PAEQR50912_34020
PSTEPSTEL_26775
PAEAR70723_32405
PAEER70331_31190
PAEHH70357_35215
PAEJH70737_30210
PBJVN24_10045
PIHUB51_21915
PRIPRIO_6792
PSONJI735_08505
PPEOABE82_25780
PNPIJ22_43130
POWIJ21_03960
PBVAR543_02735
PXLBS614_02830
PYGAWM70_19295
PSWUSY83_06820
PDHB9T62_31980
PIBBBD41_14430
PCXLPB68_12110
PKBB4V02_25390
PAIHASL14_12070
PVOPVOR_01795
PLWD5F53_30145
PLENEIM92_04850
PPSCEHS13_35780
PLUTEI981_28720
PALBEJC50_03550
PCHIPC41400_01980
PBKBack11_47540(gdpP)
PPRTET464_15090
PBACHUB98_16900
PRZGZH47_16355
PLYCGXP70_00660
PSOPKP014_03085
PTRIKDC22_33090
PALOE6C60_4173
PCELHUB94_29330
PTJJRJ22_28885
PALRHGI30_22860
TCOTheco_3790
ANXACH33_00500
ASOCCB4_00407(nrnA_1)
ATHEK3F53_18620
COHEAV92_19410
COHNKCTCHS21_61740
CCHLFPL14_13845
SACAFFV09_10490
SIVSSIL_0129
SSILSOLI23_18165
SOBCSE16_21035
PLNPlano_3000
PKUAUO94_00355
PRTAUC31_10415
PLLI858_007920
PANABBH88_03190
PDGBCM40_00205
PHCBBI08_12395
PPLABBI15_11560
PFAEAJGP001_17250
PLXCW734_18000
PMATBBI11_00760
PDECH1Q58_16175
JEOJMA_36780
KURASO14_2915
KZONCTC404_00791(nrnA_1)
SPSYAZE41_00195
SPORSporoP33_09135
SPOPSporoP37_09505
SURESporoP32a_09450
SPOSDV702_13565
SPAEE2C16_13485
RSTATY39_15030
PAEKD3873_00365
PANCE2636_17940
PLAYDNR44_003765
VIJJNUCC6_14710
NTRB0W44_17600
LFBC1X05_16550
TVUAB849_004980
KPULGXN76_15945
KEBGXN75_17255
PABSJIR001_31730
LLAL151062(yhfB)
LLKLLKF_0764(yhfB)
LLTCVCAS_0706(yhfB)
LLSlilo_0674(yhfB)
LLDP620_04090
LLXNCDO2118_0760
LLJLG36_0724(yhfB)
LLMllmg_1816
LLCLACR_0788
LLRllh_9135
LLNLLNZ_09350
LLIuc509_0751
LLWkw2_0694
LGRLCGT_0628
LGVLCGL_0647
LPKLACPI_1648
LRNCMV25_08355
LACTD7I46_01725
LACKFLP15_06560
LTIJW886_04155
LCARBHS00_02895
LPAABHS01_03090
SPYSPy_2184
SPZM5005_Spy1837
SPYMM1GAS476_188
SPYAA20_1881c
SPMspyM18_2219
SPGSpyM3_1837
SPSSPs1833
SPHMGAS10270_Spy1956
SPIMGAS10750_Spy1953
SPJMGAS2096_Spy1868
SPKMGAS9429_Spy1848
SPFSpyM51809
SPAM6_Spy1855
SPBM28_Spy1869
STGMGAS15252_1726
STXMGAS1882_1760
SOZSpy49_1790c
STZSPYALAB49_001839
SPYHL897_09125
SPNSP_2205
SPDSPD_2032
SPRspr2010
SPWSPCG_2172
SJJSPJ_2231
SNVSPNINV200_20140
SPXSPG_2151
SNTSPT_2223
SNDMYY_2128
SPNNT308_10610
SNESPN23F22380
SNCHMPREF0837_10218
SNMSP70585_2332
SPPSPP_2258
SNIINV104_19060
SPNGHMPREF1038_02213
SNBSP670_2352
SNPSPAP_2248
SNXSPNOXC19470
SNUSPNA45_02058
SPNESPN034156_10270
SPNUSPN034183_19490
SPNMSPN994038_19390
SPNOSPN994039_19400
SAGSAG2141
SANgbs2100
SAKSAK_2099
SGCA964_1988
SAGSSaSA20_1738
SAGLGBS222_1733
SAGMBSA_21530
SAGIMSA_22190
SAGRSAIL_21360
SAGPV193_09185
SAGCDN94_09185
SAGTGBSCOH1_1967
SAGEEN72_11305
SAGGEN73_10305
SAGNW903_2044
SMUSMU_2140c
SMCSmuNN2025_1873
SMUTSMUGS5_09630
SMJSMULJ23_1899
SMUASMUFR_1856
STCstr2001
STLstu2001
STESTER_1977
STNSTND_1943
STUSTH8232_2310
STWY1U_C1886
STHET303_00955
STHSAVT04_05130
SSASSA_2358
SSBSSUBM407_2005
SSUSSU05_2162
SSVSSU98_2160
SSISSU1940
SSSSSUSC84_1958
SSFSSUA7_1968
SSWSSGZ1_1958
SUPYYK_09350
SSUSNJAUSS_1980
SSTSSUST3_1985
SSUYYB51_9840
SSQSSUD9_2158
SUISSUJS14_2109
SUOSSU12_2077
SRPSSUST1_2051
SSUTTL13_1949
SSUIT15_2212
SGOSGO_0026
SEZSez_1927
SEQSZO_19110
SEZOSeseC_02575
SEQUQ426_09600
SEUSEQ_2205
SUBSUB1845
SDSSDEG_2147
SDGSDE12394_10880
SDAGGS_1947
SDCSDSE_2257
SDQSDSE167_2258
SGAGALLO_2236
SGGSGGBAA2069_c22820
SGTSGGB_2269
SMBsmi_2055
SORSOR_1946
STKSTP_1843
STBSGPB_1995
SCPHMPREF0833_11447
SCFSpaf_2083
SSRSALIVB_2128
STFSsal_00026
STJSALIVA_2059
STRSSSAL8618_10070
SSAHHSISS4_01878
STDSPPN_11235
SMNSMA_2155
SIFSinf_1936
SIESCIM_1679
SIBSIR_1873
SIUSII_1841
SANGSAIN_1808
SANCSANR_2093
SANSDK43_00265
SCGSCI_1911
SCONSCRE_1867
SCOSSCR2_1867
SOII872_10550
SIKK710_2185
SIQDQ08_10095
SIODW64_10080
SIZSI82_10000
SLUKE3_1999
SIGN596_07080
SIPN597_08990
STVV470_09650
SPATA0O21_09510
STRAATM98_06780
STRNSNAG_1858(nrnA_2)
SSOBDK181_10345
SRQSR187_9995
SEQIA6J79_02770
SKID7D50_03280
SPEIEHW89_09190
SRATFY406_02670
SGWD7D53_09260
SPLRC0J00_10235
STRGSRT_20560
SVBNCTC12167_01929
SMENSAMEA4412692_1810
SFERNCTC12278_01884(nrnA_2)
SCAINCTC12191_00637
SPSUNCTC13786_01237
SCHJDDV21_011560
SPOCNCTC10925_01913
SPABKQ224_06930
SLATJ4854_10175
SAUPNCTC3168_00803
SURNNCTC13766_00018
SACOSAME_02450
SVFNCTC3166_01945
LJOLJ_0010
LJFFI9785_73
LJHLJP_0011
LJNT285_00055
LACLBA0011
LADLA14_0010
LAFSD55_0010
LDBLdb0010
LBULBUL_0010
LDELDBND_0010
LDLLBU_0010
LGALGAS_0011
LHElhv_0016
LHLLBHH_0018
LHRR0052_00055
LHVlhe_0018
LHHLBH_0010
LHDHUO_00955
LCRLCRIS_00013
LAMLA2_00050
LAILAC30SC_00050
LAYLAB52_00050
LKEWANG_1461
LAWLACWKB8_0010
LAELBAT_0010
LGLAO203_03105
LJEBUE77_00770
LAMYB1745_00060
LPWLpgJCM5343_00110
LKLDKL58_00050
LAPIDKL56_00060
LHSDLD54_00050
LTAH1A07_00055
LUUH4B44_00050
LPAIGYM71_00060
LIDGYK47_05415
LCALSEI_0115
LCZLCAZH_0119
LCSLCBD_0109
LCELC2W_0099
LCWBN194_01120(yybT)
LCLLOCK919_0114
LPQAF91_14765
LPILBPG_01655
LPAPLBPC_0093
LCBLCABL_01090
LCXLCA12A_1044
LRHLGG_00121(yybT)
LRGLRHM_0121
LRLLC705_00118(yybT)
LRALRHK_125
LROLOCK900_0112
LRCLOCK908_0124
LCHIKG086_00485
LZEKG087_00585
LPLlp_0012
LPJJDM1_0010
LPTzj316_0238
LPSLPST_C0010
LPRLBP_cg0011
LPZLp16_0010
LPBSH83_00050
LPXASU28_00050
LPGBB562_00050
LARGLPA65_00050
LRELreu_0010
LRFLAR_0010
LRUHMPREF0538_21163
LRTLRI_0012
LRRN134_00055
LFELAF_0010
LFRLC40_0006
LFFLBFF_0010
LMULBLM1_10785
LORAYI71_04715 AYI71_09390
LVALV515_00050
LFNLF145_00050
LPONLP475_00055
LGASLG045_00050
LPASKZE55_00055
LNGBSQ50_00045
LHWBSQ49_00060
LMALLM596_00060
LSNLSA_00100(yybT)
LLEAYR59_01480
LFVLF543_00055
LBHLbuc_0014
LBNLBUCD034_0014
LPARFAM21731_01012
LCUPL11_004045
LKFDNL43_05110
LHILG8J22_00011(gdpP)
LBRLVIS_0017
LBKLVISKB_0023
LKOABN16_05580
LZYLZ3411_0020
LSUAH3M12_03540
LJIELX58_00050
LSLLSL_1728
LSIHN6_01446
LSJLSJ_1775c
LRMLRC_00130
LAGLBEN83_09750
LACALAC1533_0025
LANIFAX13_00075
LMURCPS94_08945
LBTAYR52_10250
LCYLC20004_00275
LHOLOOC260_100130
LOLLACOL_0012
LNNF0161_00095
LKUAPS55_02695
ABOMD7I45_00345
LPDAYR62_13900
LMAEFGL90_04655
PPEPEPE_0010
PPENT256_00050
PCEPECL_11
PDMADU72_1145
PACIA4V11_06935
PIOPI20285_09695
LROSLROSL1_0011
LGNABM34_08945
LHIJP39_11755
LCTBI355_2210
LALWBTM29_02990
LALILA20249_08350
LFMLF20184_00355
LZHD1B17_12655
CPABG6534_10765
LSALCA_0010
LCVFBA2_00485
LGMLG542_00050
LAHLA20533_04090
LBMDS830_07425
LHBD1010_00435
LDXLH506_00050
OOEOEOE_0013
OENDSM07_05550
OSIDLJ48_03485
LMELEUM_1967
LMMMI1_08600
LMKLMES_1719
LCILCK_00172
LKILKI_04450
LECLGMK_07975
LCNC270_07175
LGSLEGAS_0297
LGEC269_01395
LLFBCR17_03330
LGCA9176_01810
LSUA6B45_09500
LPSEFGL85_02755
WKOWKK_02140
WCEWS08_0087
WCTWS74_0086
WCIWS105_0087
WCBAO080_00460
WJOFOL01_0329
WPACO680_06660
WCFC6P13_09115
WSOWSWS_00258
WHEEFA59_01465
WDIH9L19_02125
WVRIE337_07005
WCOG7084_02620
WEIEQG49_07120
EFAEF0011
EFLEF62_0402
EFIOG1RF_10010
EFDEFD32_0010
EFSEFS1_0010
EFNDENG_00011
EFQDR75_2061
ENEENT_00650
EFCEFAU004_00015
EFAUEFAU085_00011
EFUHMPREF0351_10010
EFMM7W_232
EFTM395_00050
EHREHR_04840
ECASECBG_01158
EMUEMQU_0010
EDULIU_01255
EGAAL523_05090
ESSATZ33_13485
ETHCK496_00050
EGVEGCR1_12510
EAVEH197_00535
ESGEsVE80_00110
ELACI4Q40_00050
ECECNCTC12421_00020(ppaC_1)
ERAFJ9537_00050
EIEENLAB_18400
MPSMPTP_0011
MPXMPD5_0010
THLTEH_00100
TEYGLW17_06785
TOOC7K38_04355
TKRC7K43_10485
AURHMPREF9243_0021
AUNAWM73_08915
AUIAPT62_09510
ASANAWM72_04055
ACGAWM71_03310
AVSAWM76_00315
AUHAWM75_04615
ADCFOC79_04040
ABAECL176_12030
IRUM0R79_03080
CRNCAR_c00100(yybT)
CMLBN424_10
CAWQ783_00055
CARCNY10_1761
CDJBFC22_01185
CARNFPV25_06800
CVDLHA31_06725
MARRBKP56_02830
JEPBW721_08495 BW721_08505
JDABW727_101834(gdpP)
JEHEJN90_06040
JARG7057_05340
JPOG7058_06115
DPMFNV33_00275
GADK8O88_04770
CACCA_C3718
CAESMB_G3761(yybT)
CAYCEA_G3725
CPECPE2637
CPFCPF_2973
CPRCPR_2651
CTCCTC_00111
CTETBN906_00085
CNONT01CX_0888
CBOCBO3623
CBACLB_3716
CBHCLC_3622
CBYCLM_4128
CBLCLK_3107
CBKCLL_A3583
CBBCLD_0851
CBICLJ_B3962
CBNCbC4_0021
CBTCLH_3377
CBFCLI_3868
CBJH04402_03723
CBECbei_5082
CBZCbs_5082
CBEILF65_05762
CKLCKL_3905
CKRCKR_3447
CLJCLJU_c42740
CCBClocel_4362
CLSCXIVA_11560
CLBClo1100_0075
CSRCspa_c58200
CPASClopa_4884
CPATCLPA_c40720
CPAECPAST_c40720
CSBCLSA_c45300(yybT)
CAHCAETHG_2099
CLTCM240_2678
CBVU729_1070
CSQCSCA_4148
CLDCLSPO_c38170
CACECACET_c39220
CCKCcar_20615
CBUTATN24_01315
CTYKCTK_C30390
CEUA7L45_21850
CTAEBGI42_14530
CCHVBTM20_13365
CARGRSJ17_01625
CDRKB9W14_24420
CIABEN51_13505
CSEPCP523_07550
CDYF3K33_26100
CCOHSAMEA4530647_2467(nrnA)
CFERD4Z93_12995
CGASJ1C67_06215
CLOSDMR38_21555
CCAAKQH81_17375
CMAHC1I91_01350
AMTAmet_4770
AOEClos_2799
GFEGferi_13675
HHWNCTC503_02737(nrnA_2)
CALEFDN13_07830
CRSFQB35_15215
CPRFK7H06_19320
SARJHH195_11305
PBIFKXZ80_15950
CAZOG3A45_11840
CTHCthe_2258
CTXClo1313_2931
CCLClocl_0122
HSCHVS_01335(nrnA1)
RUKA4V00_10700
RBPB6259_07750
CCECcel_0080
RHEREHE19_000600
CTHDCDO33_00575
CCELCCDG5_0692
FPLAA4U99_00865
EHAEthha_2285
RALRumal_1644
RCHRUM_07760
RUMCK1_36360
RUSRBI_I00975
RUJE5Z56_08355
FPRFP2_16030
FPAFPR_21620
FPRACG447_14495
CAPREQM14_06070
OVAOBV_36980
OBJEIO64_07335
CAMLH6X83_03245
CLFGJQ69_02730
SMANC12CBH8_15250
PFAAMM59RIKEN_15430
VFAMM35RIKEN_18650
VCOPMM50RIKEN_20650
CFEMHCR03_03655
ACOLK5I23_12030
BPBbpr_I0265
BFICIY_29730
BHUbhn_I2532
CLEClole_1075
CEWEKH84_08120
RHORHOM_16625
RIXRO1_31310
RIMROI_33960
COOCCU_20480
CCTCC1_15200
CCOMI6K69_08665
CEVLK421_06315
ROBCK5_06100
BYLA4V09_02155
BHANCGC63_03135
BLAUDQQ01_03555
BPROPMF13cell1_05038(gdpP)
BLABEYS05_01305
BLIQINP51_04185
CPYCphy_3758
LACYA4V08_15315
CSCIHDCHBGLK_01387(gdpP)
CSHClosa_0308
CSOCLS_10110
BPRLCL2_19020
ARFAR1Y2_0296
ACACEYQ97_15240
HSDSD1D_0155
CPROCPRO_26430(nrnA_2)
LUAD4A81_07870
EHLEHLA_3188
PXVFXF36_04100
ANRAna3638_04260
ACELacsn021_43000
ACHTbsdcttw_02950
EELEUBELI_01952
RTORTO_00420
RGNRGna_10220
CBOLCGC65_01520
DLOK5I24_08925
SINTK5I26_01245
WCPH9Q76_13215
EREEUBREC_3260
ERTEUR_05510
ERAERE_13970
LBWC3V36_02890
CDFCD630_36590
PDCCDIF630_03987
CDCCD196_3472
CDLCDR20291_3518
PDFCD630DERM_36590
EACEAL2_c22080(yybT)
CSTCLOST_2566(yybT)
FAAHMPREF0389_01693
PSORRSJ16_17525
ROCHF520_13095
PHXKGNDJEFE_00211(gdpP)
TEMJW646_09485
TEBT8CH_3531
PBQC3V37_02915
TFRBR63_12980
FWADCMF_16970
HMOHM1_0972
HCVFTV88_0899 FTV88_0900
ELMELI_4578
EMTCPZ25_013130
ELIMB2M23_03060
AWOAwo_c35480
ALKAJ0B03_06900
CMIUB1H56_08325
IBUIB211_03211
CBARPATL70BA_1957
VGUHYG85_11435
VPYHZI73_00795
LASAL9O85_12475
MDVC5Q96_07430
AMIJEQM06_00185
AMICAmi3637_07285
ABUTAmi103574_01150
ETMCE91St48_40830
EUUADJ67_00670
BPRSCK3_09210
TTETTE2776
THXThet_2438
TPDTeth39_2270
TITThit_2381
TMTTmath_2261
TBOThebr_2315
TKITKV_c24560
TPZTph_c00770
GEKkuro4_06470
CSCCsac_1464
ATEAthe_0880
COBCOB47_0813
CHDCalhy_1810
COWCalow_0720
CKICalkr_0648
CLCCalla_1716
CKNCalkro_1774
CCHAELD05_04350
CDIACaldiYA01_15930
TTMTthe_2730
TTOThethe_02750
TXYThexy_2388
TSHTsac_0525
MASMahau_2622
TEPTepRe1_2615
TAETepiRe1_2822
TOCToce_2253
KMEH0A61_01020(gdpP)
FMAFMG_0088
APRApre_0533
AVGI6H45_06410
AOBI6H46_00200
AMEILV469_06200
PMICNW74_00985
PEDING2D1G_0120
PHARNCTC13077_01561(nrnA_2)
PIVNCTC13079_01216(ppaC)
MHAPJFY71_00590
CADCuri_c28540
SPOAEQM13_00175
KPARJL105_00245
SEDZJYG23_09745
VPRVpar_1683
VATB7L28_08720
VRM44547418_01780(nrnA_2)
VDNNCTC11831_01854(nrnA_2)
VNKVEIT17_17530
MEDMELS_0735
MHWACT01_03745
MEGDKB62_04345
MMAXLCQ47_06220
DPNBCB69_00240
DHODia5BBH33_17980
SSGSelsp_2051
SRISELR_00090
SELEADJ74_04505
SELOAXE86_05420
SELTBCS37_11085
MHGMHY_06640
MFUNGXM21_00315
PUFUFO1_4533
PFTJBW_04724
MANAMAMMFC1_01273(nrnA_1)
STEDSPTER_45190(gdpP)
AFNAcfer_0042
AINAcin_2414
PFACPFJ30894_00314(nrnA_1)
ERHERH_1588
ERSK210_06450
ERLAOC36_10925
ERDG7062_00910
EIOH9L01_03425
EUCEC1_03090
FROAALO17_07660
AARGAargi30884_16790
ABSIA9CBEGH2_15400
CIUG4D55_02880
ERMEYR00_01460
FITFi14EGH31_00850(gdpP)
BULLJOS54_00795
EBMSG0102_28910(gdpP)
LCGL3BBH23_27450
AMUOKWG62_09160
ERBA4V01_04565
TURAT726_04335
TSGHLK68_02995
MCDMCRO_0438
MYGASO20_01690
MANSFRW55_00935
MNHFG904_02015
MSTREGN60_01325
MTAUJS510_00245
MMIRHLA87_02980
MMIOHLA92_03190
MPHEHGG69_00470
MMOMMOB1730
MHYmhp666
MHJMHJ_0646
MHPMHP7448_0646
MHNMHP168_656
MHYLMHP168L_656
MHYOMHL_3149
MCOMCJ_001700
MHRMHR_0233
MHHMYM_0354
MHMSRH_00780
MHSMOS_263
MHVQ453_0383
MBCMYB_02170
MFQMYF_03100
MDSMDIS_03910
MNUNCTC10166_00762 NCTC10166_00904
MOENCTC10151_00675
MCRMCFN_00890
MCMMCAL160_0795(dhh3)
MGBVO56_00215
MGLYNCTC10194_00409
MCOUNCTC10179_00353
MCOMNCTC10178_00447(ppaC)
MPUMYPU_5170(MYPU_5170)
MSYMS53_0427
MSOVY93_02295
MAAMAG2360
MALMAGa2520
MFRMFE_06540
MFMMfeM64YM_0770
MFPMBIO_0098
MBVMBOVPG45_0583
MBHMMB_0255
MBIMbov_0276
MBQK668_01290
MCYMCYN_0677(MCYN0677)
MCASAAW50_01240
MCKAXW82_01190
MARGMARG145_0280
MPULBLA55_03005
MBOVMBVG596_1017
MBOHCO229_02315
MANIDP067_00305
MPHIEG856_02460
MFELJPM2_5390(gdpP)
MGALNCTC10186_00514(nrnA_1)
MCITNCTC10181_00898
MMAUNCTC10168_00716
MMELNCTC10153_00233(ppaC)
MCOBNCTC10184_00301
POYPAM_012
AYWAYWB_006
MBPMBSPM3_v1c0160(rplI)
PMLATP_00177(rplI)
PALPA0149
NZSSLY_0889(rplI)
PSOLS284_02750(rplI)
PZICWO85_01820(rplI)
PLUFLFWB_3140(rplI) LFWB_4510(rplI)
ACLACL_0196
AOCAocu_12700(rplI)
AHKNCTC10172_00925(rplI)
ABRABN85303190(rplI)
APALBN85412540(rplI)
AAXANCTC10138_00580(rplI)
MANRMPAN_003240
MATMARTH_orf692
MHOMHO_3930
MHOMMLBD4_02310
MCANMCAN360_0357
MPHODA803_01975
MHYVMHSN_00745
MCLODK849_00200
MPHCDMC14_000145
MANEDP065_01710
MALANCTC10135_00865
MSAINCTC10113_01317(ppaC)
MBJKQ51_00116(rplI)
TBMBK010_01745
TBZBK011_01630
TBKHF295_05155(rplI)
ACITHPK19_17775
TRCDYE49_02840
 » show all
Reference
1  [PMID:19901023]
  Authors
Rao F, See RY, Zhang D, Toh DC, Ji Q, Liang ZX
  Title
YybT is a signaling protein that contains a cyclic dinucleotide phosphodiesterase domain and a GGDEF domain with ATPase activity.
  Journal
J Biol Chem 285:473-82 (2010)
DOI:10.1074/jbc.M109.040238
  Sequence
[bsu:BSU40510]
Reference
2  [PMID:21909268]
  Authors
Corrigan RM, Abbott JC, Burhenne H, Kaever V, Grundling A
  Title
c-di-AMP is a new second messenger in Staphylococcus aureus with a role in controlling cell size and envelope stress.
  Journal
PLoS Pathog 7:e1002217 (2011)
DOI:10.1371/journal.ppat.1002217
  Sequence
Reference
3  [PMID:21986827]
  Authors
Griffiths JM, O'Neill AJ
  Title
Loss of function of the gdpP protein leads to joint beta-lactam/glycopeptide tolerance in Staphylococcus aureus.
  Journal
Antimicrob Agents Chemother 56:579-81 (2012)
DOI:10.1128/AAC.05148-11
  Sequence
Reference
4  [PMID:27834680]
  Authors
Bowman L, Zeden MS, Schuster CF, Kaever V, Grundling A
  Title
New Insights into the Cyclic Di-adenosine Monophosphate (c-di-AMP) Degradation Pathway and the Requirement of the Cyclic Dinucleotide for Acid Stress Resistance in Staphylococcus aureus.
  Journal
J Biol Chem 291:26970-26986 (2016)
DOI:10.1074/jbc.M116.747709
Other DBs
ExplorEnz - The Enzyme Database: 3.1.4.59
IUBMB Enzyme Nomenclature: 3.1.4.59
ExPASy - ENZYME nomenclature database: 3.1.4.59
BRENDA, the Enzyme Database: 3.1.4.59

DBGET integrated database retrieval system