| Entry |
|
|---|
| Name |
glucuronate-2-sulfatase;
glucurono-2-sulfatase
|
|---|
| Class |
Hydrolases;
Acting on ester bonds;
Sulfuric-ester hydrolases
|
|---|
| Sysname |
polysaccharide-2-O-sulfo-D-glucuronate 2-sulfohydrolase
|
|---|
| Reaction(IUBMB) |
Hydrolysis of the 2-sulfate groups of the 2-O-sulfo-D-glucuronate residues of chondroitin sulfate, heparin and heparitin sulfate [RN: R07817]
|
|---|
| Reaction(KEGG) |
|
|---|
| Comment |
Does not act on iduronate 2-sulfate residues (cf. EC 3.1.6.13 iduronate-2-sulfatase)
|
|---|
| History |
EC 3.1.6.18 created 1989
|
|---|
| Pathway |
| ec00531 | Glycosaminoglycan degradation |
|
|---|
| Reference |
|
|---|
| Authors |
Shaklee PN, Glaser JH, Conrad HE. |
|---|
| Title |
A sulfatase specific for glucuronic acid 2-sulfate residues in glycosaminoglycans. |
|---|
| Journal |
J Biol Chem 260:9146-9 (1985) |
|---|
| Other DBs |
| ExplorEnz - The Enzyme Database: | 3.1.6.18 |
| ExPASy - ENZYME nomenclature database: | 3.1.6.18 |
|
|---|
