Entry |
|
Name |
N-acetylgalactosamine-6-sulfatase;
chondroitin sulfatase;
chondroitinase;
galactose-6-sulfate sulfatase;
acetylgalactosamine 6-sulfatase;
N-acetylgalactosamine-6-sulfate sulfatase;
N-acetylgalactosamine 6-sulfatase
|
Class |
Hydrolases;
Acting on ester bonds;
Sulfuric-ester hydrolases
|
Sysname |
N-acetyl-D-galactosamine-6-sulfate 6-sulfohydrolase
|
Reaction(IUBMB) |
Hydrolysis of the 6-sulfate groups of the N-acetyl-D-galactosamine 6-sulfate units of chondroitin sulfate and of the D-galactose 6-sulfate units of keratan sulfate [RN: R07806]
|
Reaction(KEGG) |
|
History |
EC 3.1.6.4 created 1961
|
Pathway |
ec00531 | Glycosaminoglycan degradation |
|
Orthology |
K01132 | N-acetylgalactosamine-6-sulfatase |
|
Genes |
» show all
|
Reference |
|
Authors |
Epstein EH Jr, Leventhal ME. |
Title |
Steroid sulfatase of human leukocytes and epidermis and the diagnosis of recessive X-linked ichthyosis. |
Journal |
|
Reference |
|
Authors |
Glossl J, Kresse H. |
Title |
Impaired degradation of keratan sulphate by Morquio A fibroblasts. |
Journal |
|
Reference |
|
Authors |
Lim CT, Horwitz AL. |
Title |
Purification and properties of human N-acetylgalactosamine-6-sulfate sulfatase. |
Journal |
|
Reference |
|
Authors |
Sorensen SH, Noren O, Sjostrom H, Danielsen EM. |
Title |
Amphiphilic pig intestinal microvillus maltase/glucoamylase. Structure and specificity. |
Journal |
|
Reference |
|
Authors |
Yutaka T, Okada S, Kato T, Inui K, Yabuuhi H. |
Title |
Galactose 6-sulfate sulfatase activity in Morquio syndrome. |
Journal |
|
Other DBs |
ExplorEnz - The Enzyme Database: | 3.1.6.4 |
ExPASy - ENZYME nomenclature database: | 3.1.6.4 |
BRENDA, the Enzyme Database: | 3.1.6.4 |
|