| Entry |
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| Name |
N-acetylgalactosamine-6-sulfatase;
chondroitin sulfatase;
chondroitinase;
galactose-6-sulfate sulfatase;
acetylgalactosamine 6-sulfatase;
N-acetylgalactosamine-6-sulfate sulfatase;
N-acetylgalactosamine 6-sulfatase
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| Class |
Hydrolases;
Acting on ester bonds;
Sulfuric-ester hydrolases
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| Sysname |
N-acetyl-D-galactosamine-6-sulfate 6-sulfohydrolase
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| Reaction(IUBMB) |
Hydrolysis of the 6-sulfate groups of the N-acetyl-D-galactosamine 6-sulfate units of chondroitin sulfate and of the D-galactose 6-sulfate units of keratan sulfate [RN: R07806]
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| Reaction(KEGG) |
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| History |
EC 3.1.6.4 created 1961
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| Pathway |
| ec00531 | Glycosaminoglycan degradation |
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| Orthology |
| K01132 | N-acetylgalactosamine-6-sulfatase |
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| Genes |
» show all
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| Reference |
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| Authors |
Epstein EH Jr, Leventhal ME. |
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| Title |
Steroid sulfatase of human leukocytes and epidermis and the diagnosis of recessive X-linked ichthyosis. |
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| Journal |
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| Reference |
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| Authors |
Glossl J, Kresse H. |
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| Title |
Impaired degradation of keratan sulphate by Morquio A fibroblasts. |
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| Journal |
Biochem J 203:335-8 (1982) |
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| Reference |
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| Authors |
Lim CT, Horwitz AL. |
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| Title |
Purification and properties of human N-acetylgalactosamine-6-sulfate sulfatase. |
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| Journal |
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| Reference |
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| Authors |
Sorensen SH, Noren O, Sjostrom H, Danielsen EM. |
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| Title |
Amphiphilic pig intestinal microvillus maltase/glucoamylase. Structure and specificity. |
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| Journal |
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| Reference |
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| Authors |
Yutaka T, Okada S, Kato T, Inui K, Yabuuhi H. |
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| Title |
Galactose 6-sulfate sulfatase activity in Morquio syndrome. |
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| Journal |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 3.1.6.4 |
| ExPASy - ENZYME nomenclature database: | 3.1.6.4 |
| BRENDA, the Enzyme Database: | 3.1.6.4 |
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