KEGG   ENZYME: 3.1.7.10
Entry
EC 3.1.7.10                 Enzyme                                 

Name
(13E)-labda-7,13-dien-15-ol synthase;
labda-7,13E-dien-15-ol synthase
Class
Hydrolases;
Acting on ester bonds;
Diphosphoric-monoester hydrolases
Sysname
geranylgeranyl-diphosphate diphosphohydrolase [(13E)-labda-7,13-dien-15-ol-forming]
Reaction(IUBMB)
geranylgeranyl diphosphate + H2O = (13E)-labda-7,13-dien-15-ol + diphosphate [RN:R09874]
Reaction(KEGG)
R09874
Substrate
geranylgeranyl diphosphate [CPD:C00353];
H2O [CPD:C00001]
Product
(13E)-labda-7,13-dien-15-ol [CPD:C20158];
diphosphate [CPD:C00013]
Comment
The enzyme from the lycophyte Selaginella moellendorffii is bifunctional, initially forming (13E)-labda-7,13-dien-15-yl diphosphate, which is hydrolysed to the alcohol.
History
EC 3.1.7.10 created 2012
Pathway
ec00904  Diterpenoid biosynthesis
ec01110  Biosynthesis of secondary metabolites
Orthology
K16086  (13E)-labda-7,13-dien-15-ol synthase
Genes
SMO: SELMODRAFT_112927 SELMODRAFT_120716
Reference
1  [PMID:21751328]
  Authors
Mafu S, Hillwig ML, Peters RJ
  Title
A novel labda-7,13e-dien-15-ol-producing bifunctional diterpene synthase from Selaginella moellendorffii.
  Journal
Chembiochem 12:1984-7 (2011)
DOI:10.1002/cbic.201100336
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 3.1.7.10
IUBMB Enzyme Nomenclature: 3.1.7.10
ExPASy - ENZYME nomenclature database: 3.1.7.10
BRENDA, the Enzyme Database: 3.1.7.10

  All links  
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (2)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
Protein domain (6)   
   InterPro (6)   
All databases (22)   

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