KEGG   ENZYME: 3.2.1.123
Entry
EC 3.2.1.123                Enzyme                                 
Name
endoglycosylceramidase;
endoglycoceramidase;
EGCase;
glycosyl-N-acetyl-sphingosine 1,1-beta-D-glucanohydrolase;
oligoglycosylglucosylceramide glycohydrolase;
oligoglycosylglucosyl(1<->1)ceramide glycohydrolase
Class
Hydrolases;
Glycosylases;
Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
Sysname
oligoglycosylglucosyl-(1<->1)-ceramide glycohydrolase
Reaction(IUBMB)
oligoglycosylglucosyl-(1<->1)-ceramide + H2O = ceramide + oligoglycosylglucose [RN:R04118 R06157]
Reaction(KEGG)
R04118 R06157(G);
(other) R06283(G)
Substrate
oligoglycosylglucosyl-(1<->1)-ceramide;
H2O [CPD:C00001]
Product
ceramide [CPD:C00195];
oligoglycosylglucose [CPD:C03018]
Comment
An enzyme from Rhodococcus sp. that degrades various acidic and neutral glycosphingolipids to oligosaccharides and ceramides, by cleaving a glucosyl bond. Does not act on monoglycosylceramides. cf. EC 3.2.1.62 glycosylceramidase.
History
EC 3.2.1.123 created 1989
Orthology
K05991  endoglycosylceramidase
Genes
BFO118407464 118407480
BBEL109477355
FCD110852051
EAF111706602 111709234 111709909
LSM121116947
HROHELRODRAFT_86747
LAK106179962
SMMSmp_120050 Smp_155570 Smp_164170 Smp_187070 Smp_193630
OVIT265_04204 T265_13449
NVE5501331 5516730
EPA110232166
ATEN116296699 116296702
ADF107334423
AMIL114950972
PDAM113667552
SPIS111330991
DGT114533612
XEN124440633
HMG100192295
AQU100634050 100639716
PPP112281139
CSLCOCSUDRAFT_68001
FVRFVEG_12913
FOXFOXG_16909
MAWMAC_02340
MAJMAA_10290
CMTCCM_04551
PLJVFPFJ_06511
AFMAFUA_5G00550
NFINFIA_041960
AORAO090012000006
AFVAFLA_001713
TMSTREMEDRAFT_61952
MBRMONBRDRAFT_1029 MONBRDRAFT_9488
SREPTSG_04956 PTSG_12288
DDIDDB_G0270074
DPPDICPUDRAFT_148335
DFADFA_08187 DFA_12093
ACANACA1_251790
TETTTHERM_00283480 TTHERM_00283490 TTHERM_00429930 TTHERM_00476450
PTMGSPATT00026357001 GSPATT00029272001 GSPATT00031065001 GSPATT00032672001
SMINv1.2.006292.t1(symbB.v1.2.006292.t1)
AAFAURANDRAFT_23504(EGN1)
EHXEMIHUDRAFT_66695
GTTGUITHDRAFT_157591 GUITHDRAFT_46636
NGRNAEGRDRAFT_32211
LCPLC55x_3709
ZALAZF00_16475
KAKKalk_10570
SOKD0B54_08670
GPBHDN1F_20130
BCNBcen_5206
BCHBcen2424_5653
PMEGFNZ07_03730
PAUUE8A73_021165
SAMYDB32_006343
MRMA7982_09064
NOVTQ38_028330
SPHBEP837_03631
BTROFJR70_30715
PLWD5F53_31055
LHBD1010_01990
VGUHYG85_14075
MKNMKAN_03410
MYEAB431_05450 AB431_09420
MNMMNVM_09570 MNVM_09580 MNVM_20330 MNVM_24980
MCOOMCOO_48690
MHERK3U94_02935 K3U94_02940 K3U94_02955 K3U94_04795 K3U94_04850 K3U94_11020 K3U94_15655 K3U94_22645
MPAEK0O64_08875
MVMMJO54_02935 MJO54_02940 MJO54_22715
MRFMJO55_17130
MPAAMKK62_16900
MCROMI149_10085
MCBMycch_1466
MAICMAIC_16130
MPSCMPSYJ_29730
MHEVMHEL_40280
MSARMSAR_01450
MAUBMAUB_39620
MPHUMPHO_30170
MMUCC1S78_003840
MJDJDM601_0882 JDM601_0884 JDM601_3582 JDM601_4151
MTER4434518_00844 4434518_04091
MMINMMIN_11060 MMIN_15890 MMIN_22200 MMIN_22210 MMIN_22230 MMIN_25070 MMIN_25080
MHIBMHIB_03760 MHIB_03770 MHIB_21720 MHIB_21730 MHIB_29810 MHIB_40340
CKPckrop_1577
CFNCFAL_10950
COADR71_1819
CAMCI6I65_00495
NBRO3I_025405
NSLBOX37_23115
NSRNS506_00675 NS506_07799
NTPCRH09_35285
NOZDMB37_02055
NODFOH10_27820
NAHF5544_23650 F5544_31250 F5544_31470
NADNCTC11293_05611
NIEKV110_15315 KV110_22185
NTCKHQ06_02860 KHQ06_36855 KHQ06_36860
NHUH0264_04770 H0264_11865 H0264_21890
NYALTV02_28030
RERRER_26700 RER_56930
REYO5Y_12270 O5Y_27195
REBXU06_12465 XU06_27470
RQIC1M55_13505 C1M55_29060
REQREQ_10740 REQ_13700 REQ_38260
RHODAOT96_08730 AOT96_23705
TOYFO059_00195 FO059_17720
SGRSGR_2234
SGBWQO_24285
SHYSHJG_7711
SHOSHJGH_7473
SVESVEN_4954
SFISFUL_5095
SCIB446_00590 B446_34700
SALUDC74_8045
SALLSAZ_41555
SGUSGLAU_02095
SVTSVTN_25570
STREGZL_00745
SLDT261_7793
SLCSL103_19175
SPRISPRI_2608
SCZABE83_11055
SRWTUE45_07374
SRNA4G23_03887(celC)
SALWCP975_00460
SNRSNOUR_03555
SPLULK06_028855
SVUB1H20_24815
SGVB1H19_05605
SLAUSLA_5106
SALFSMD44_08570
SALJSMD11_2261
SLXSLAV_36905
STROSTRMOE7_07720
SFKKY5_5124
SLKSLUN_26690
SKACP970_15640
SVNCP980_00800
SRKFGW37_22145
SFICEIZ62_10445
SVRCP971_10155
SCAVCVT27_23580
SCINCP977_23360
SGXH4W23_27075
SSPBCP982_40440
SPLACP981_30240
SATAC5746_27945
SHUNDWB77_02953
SCYGS1361_33585(celC)
SDWK7C20_35075
SCALI6J39_24570
SAUHSU9_000080 SU9_033765
SFBCP974_21045
SMOBJ7W19_21870
SPEUCGZ69_23835
SXNIAG42_14050
SHKJ2N69_35545
SANUK7396_00620
SDDD9753_04620
SACTDMT42_35700
SGOBtest1122_18915
SINEKI385_42030
KABB7C62_25385
KAUB6264_05235
KITCFP65_5323
LSEF1C12_07170
MVDAWU67_04485
AGYATC03_16595
AMAUDSM26151_27750
ARMART_1927
GPRJQN66_06030
BCVBcav_2260
BRVCFK39_10330
BRZCFK38_00380
PSEIGCE65_05745
PACPPA0644 PPA2106
PAKHMPREF0675_3711 HMPREF0675_5160
PAVTIA2EST22_03250 TIA2EST22_10250
PAXTIA2EST36_03225 TIA2EST36_10230
PAZTIA2EST2_03170 TIA2EST2_10190
PAWPAZ_c06820 PAZ_c21810
PADTIIST44_03240 TIIST44_11280
PCNTIB1ST10_03325 TIB1ST10_10695
PACCPAC1_03350 PAC1_10690
PACHPAGK_1485 PAGK_2000
PACNTIA1EST1_03240 TIA1EST1_10305
CACNRN83_03740 RN83_10745
PRAPALO_00580
PRLBCB70_07915
MIKFOE78_19485
TDFH9L22_09625
NCANoca_3558
NBEBack2_27870
NAROCFH99_08485
AEBC6I20_12985
NALB005_1763
NGVCDO52_02365
NFEHUT17_01340
NEXNE857_33290
ACTWF7P10_25690
SROSros_1713
SENSACE_3752
ACTIUA75_06875
ACADUA74_06880
AHGAHOG_06610
CATICS0771_61510
SNASnas_0664
APHOJTE88_00990
AEYCDG81_11150
CWOCwoe_0370
PARNNBH00_04345
AQZKSP35_14740
IAMHC251_12135
SACISinac_0727
VBLL21SP4_00071 L21SP4_00900
LBILEPBI_I2486
LBFLBF_2411
LAJA0128_03105
LKMEFP84_13910
PCOPI6J50_01230
ESTDN752_23380
MAREEJ994_10175
SEONBWZ22_10440
FEKC1H87_00625
 » show all
Reference
1  [PMID:3771534]
  Authors
Ito M, Yamagata T.
  Title
A novel glycosphingolipid-degrading enzyme cleaves the linkage between the oligosaccharide and ceramide of neutral and acidic glycosphingolipids.
  Journal
J Biol Chem 261:14278-82 (1986)
Other DBs
ExplorEnz - The Enzyme Database: 3.2.1.123
IUBMB Enzyme Nomenclature: 3.2.1.123
ExPASy - ENZYME nomenclature database: 3.2.1.123
BRENDA, the Enzyme Database: 3.2.1.123
CAS: 105503-61-5

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