KEGG   ENZYME: 3.2.1.169
Entry
EC 3.2.1.169                Enzyme                                 
Name
protein O-GlcNAcase;
OGA;
glycoside hydrolase O-GlcNAcase;
O-GlcNAcase;
BtGH84;
O-GlcNAc hydrolase
Class
Hydrolases;
Glycosylases;
Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
Sysname
[protein]-3-O-(N-acetyl-beta-D-glucosaminyl)-L-serine/threonine N-acetylglucosaminyl hydrolase
Reaction(IUBMB)
(1) [protein]-3-O-(N-acetyl-beta-D-glucosaminyl)-L-serine + H2O = [protein]-L-serine + N-acetyl-D-glucosamine  [RN:R09672];
(2) [protein]-3-O-(N-acetyl-beta-D-glucosaminyl)-L-theronine + H2O = [protein]-L-threonine + N-acetyl-D-glucosamine [RN:R09673]
Reaction(KEGG)
R09672 R09673
Substrate
[protein]-3-O-(N-acetyl-beta-D-glucosaminyl)-L-serine [CPD:C19802];
H2O [CPD:C00001];
[protein]-3-O-(N-acetyl-beta-D-glucosaminyl)-L-theronine
Product
[protein]-L-serine [CPD:C02189];
N-acetyl-D-glucosamine [CPD:C00140];
[protein]-L-threonine [CPD:C19803]
Comment
Within higher eukaryotes post-translational modification of protein serines/threonines with N-acetylglucosamine (O-GlcNAc) is dynamic, inducible and abundant, regulating many cellular processes by interfering with protein phosphorylation. EC 2.4.1.255 (protein O-GlcNAc transferase) transfers GlcNAc onto substrate proteins and EC 3.2.1.169 (protein O-GlcNAcase) cleaves GlcNAc from the modified proteins.
History
EC 3.2.1.169 created 2011
Orthology
K15719  protein O-GlcNAcase / histone acetyltransferase
Genes
HSA10724(OGA)
PTR450691(OGA)
PPS100979884(OGA)
GGO101124144(OGA)
PON100459796(OGA)
PPYG129006733(OGA)
NLE100586192(OGA)
HMH116484656(OGA)
SSYN129467044(OGA)
MCC712370(OGA)
MCF102142813(OGA)
MTHB126962741
MNI105478362(OGA)
CSAB103216418(MGEA5)
CATY105581866(MGEA5)
PANU101015029(OGA)
TGE112632177(OGA)
MLEU105537773(MGEA5)
RRO104656503(OGA)
RBB108515105(MGEA5)
TFN117067826(OGA)
PTEH111538829(OGA)
CANG105507116(MGEA5)
CJC100392114(OGA)
SBQ101029093(MGEA5)
CIMI108306269(OGA)
ANAN105708171(OGA)
CSYR103252566(MGEA5)
MMUR105874010(MGEA5)
LCAT123650101(OGA)
PCOQ105824311(MGEA5)
OGA100955878 100966970(MGEA5)
MMU76055(Oga)
MCAL110285308(Oga)
MPAH110313432(Mgea5)
RNO154968(Oga)
MCOC116103925(Oga)
ANU117718833(Oga)
MUN110556269(Oga)
CGE100751586(Oga)
MAUA101829565(Oga)
PROB127233458(Oga)
PLEU114708145(Oga)
MORG121453825(Oga)
MFOT126503447
AAMP119811350(Oga)
NGI103744007(Mgea5)
HGL101702515(Mgea5)
CPOC100721083(Mgea5)
CCAN109691315(Mgea5)
DORD105986691(Mgea5)
DSP122116006(Oga)
PLOP125346135(Oga)
NCAR124984739
MMMA107149823(Oga)
OCU100351779(OGA)
OPI101534359(OGA)
TUP102491291(MGEA5)
GVR103595411(MGEA5)
CFA477802(OGA)
CLUD112672225(OGA)
VVP112915175(OGA)
VLG121484059(OGA)
NPO129523334(OGA)
AML100472078(OGA)
UMR103679457(OGA)
UAH113251855(OGA)
UAR123795891(OGA)
ELK111144756
LLV125084469
MPUF101688735(MGEA5)
MNP132016718(OGA)
MLK131828517(OGA)
NVS122901039(OGA)
ORO101374982(MGEA5)
EJU114205483(OGA)
ZCA113920795(OGA)
MLX118025273(OGA)
NSU110589710(OGA)
LWW102729315(OGA)
FCA101098493(OGA)
PYU121037144(OGA)
PCOO112854310(OGA)
PBG122493164(OGA)
PVIV125147724(OGA)
LRUF124507078
PTG102959286(MGEA5)
PPAD109272801(MGEA5)
PUC125932886
AJU106966947(OGA)
HHV120239568(OGA)
BTA538561(OGA)
BOM102279409(MGEA5)
BIU109578999(MGEA5)
BBUB102398663(OGA)
BBIS105002689(MGEA5)
CHX102179540(MGEA5)
OAS101113978(OGA)
BTAX128067753(OGA)
ODA120873553(OGA)
CCAD122445997(OGA)
MBEZ129555421(OGA)
SSC100152585(MGEA5)
CFR102507074(OGA)
CBAI105081720(MGEA5)
CDK105084341(OGA)
VPC102529685(OGA) 102541709
BACU103001043(MGEA5)
BMUS118882461(OGA)
LVE103070168(MGEA5)
OOR101288973(OGA)
DLE111172372(OGA)
PCAD102973862(OGA)
PSIU116741261(OGA)
NASI112392948(OGA)
ECB100060245(MGEA5)
EPZ103551392(MGEA5)
EAI106828857(OGA)
MYB102258473(MGEA5)
MYD102763853(MGEA5)
MMYO118669820(OGA)
MLF102432555(MGEA5)
MDT132214261(OGA)
PKL118718900(OGA)
EFUS103288497(OGA)
MNA107542582(MGEA5)
DRO112300370(MGEA5)
SHON118999490(OGA)
AJM119059637(OGA)
PDIC114496600(OGA)
PHAS123828685(OGA)
MMF118632007(OGA)
PPAM129077132(OGA)
HAI109379646(MGEA5)
RFQ117035786(OGA)
PALE102892734(OGA)
PGIG120609167(OGA)
PVP105304649(MGEA5)
RAY107497783(MGEA5)
MJV108405927(OGA)
TOD119233350(OGA)
SARA101539979(MGEA5)
SETR126033807(OGA)
LAV100660277(MGEA5)
TMU101348318
ETF101659709(OGA)
DNM101425388(MGEA5)
MDO100023348(MGEA5)
GAS123238135(OGA)
SHR100924785(OGA)
AFZ127551504
PCW110194632(MGEA5)
TVP118828036(OGA)
OAA100086916(OGA)
GGA423851(OGA) 430422
PCOC116226056 116231682(OGA)
MGP100550244(OGA) 116216702
CJO107306849 107315982(OGA)
TPAI128071978 128077675(OGA)
LMUT125692665 125693201(OGA)
NMEL110390931 110399611(MGEA5)
APLA101798266(OGA) 101803302
ACYG106035955(OGA) 106043195
CATA118248640(OGA) 118260602
AFUL116488955 116491128(OGA)
TGU100217691 100222791(OGA)
LSR110468741 110473663(OGA)
SCAN103814148(OGA) 103823117
PMOA120502106(OGA) 120509741
OTC121335221 121341962(OGA)
PRUF121350033(OGA) 121364720
GFR102039689(MGEA5) 102041996
FAB101807026(MGEA5) 101820674
OMA130252076 130254789(OGA)
PHI102099607 102100524(MGEA5)
PMAJ107203361 107206955(OGA)
CCAE111929151 111930940(MGEA5)
CCW104690840 104697891(OGA)
CBRC103621146 103624547(MGEA5)
ETL114068881 114070525(OGA)
ZAB102063529(OGA) 102073146
ZLE135447175 135449363(OGA)
ACHL103800496(MGEA5)
SVG106853115 106859001(MGEA5)
MMEA130575440 130581815(OGA)
HRT120752863 120755605(OGA)
SATI136360315 136364091(OGA)
FPG101911645 101920070(MGEA5)
FCH102050212 102050673(OGA)
CCRI104165700(MGEA5)
NNT104401327(MGEA5)
SHAB115603599 115607924(OGA)
ACUN113481496(OGA) 113490509
TALA104359393(OGA) 116962506
ACHC115338036 115348140(OGA)
HALD104319922(MGEA5)
HLE104830120(MGEA5) 104832337
AGEN126035202 126042589
GCL127015487 127018099
CSTI104552597(MGEA5)
LDI104348722(MGEA5)
MNB103771516(MGEA5)
DPUB104307157(MGEA5)
AVIT104269727(MGEA5)
BRHI104502019(MGEA5)
EGZ104125639(MGEA5)
NNI104013575(MGEA5)
PCRI104024913(MGEA5)
PCAO104048430(MGEA5)
PADL103916317(MGEA5) 103922179
AFOR103897881(MGEA5) 103902150
FGA104079075(MGEA5)
GSTE104259979(MGEA5)
CLV102086261 102092419(MGEA5)
MUI104545503(MGEA5)
PGUU104458602(MGEA5)
PLET104627734(MGEA5)
EHS104510925(MGEA5)
CMAC104484642(MGEA5)
CUCA104056877 104059798(OGA)
TEO104375715(MGEA5)
BREG104632655 104632999(MGEA5)
OHA104337966(MGEA5)
ACAR104526770(OGA)
CPEA104390870(MGEA5) 104398133
CVF104294630(MGEA5)
RTD128910109 128910828(OGA)
AAM106487392 106496884(MGEA5)
AROW112967879(OGA) 112978201
NPD112957020(OGA)
TGT104578767(MGEA5)
DNE112984773(OGA)
SCAM104138159(MGEA5)
ASN102378650 102387046(OGA)
AMJ102563356(MGEA5) 106740206
CPOO109323917(MGEA5) 109324416
GGN109287545(MGEA5)
PSS102451920(OGA)
CMY102948301(OGA)
CCAY125639672(OGA)
DCC119859542(OGA)
CPIC101934313(OGA)
TST117879788(OGA)
CABI116833940(OGA)
MRV120409101(OGA)
ACS100559082(mgea5)
ASAO132770878(OGA)
PVT110077588(MGEA5)
SUND121927346(OGA)
PBI103061735(OGA)
PMUR107285267(OGA)
CTIG120302560(OGA)
TSR106549157(MGEA5)
PGUT117678619(OGA)
APRI131200560(OGA)
PTEX113436667(OGA)
NSS113414317(OGA)
VKO123026895(OGA)
PMUA114597566(OGA)
PRAF128414315(OGA)
ZVI118093544(OGA)
HCG128352314(OGA)
GJA107114456(MGEA5)
STOW125437577(OGA)
EMC129332917(OGA)
XLA108696157(oga.L) 108697432(oga.S)
XTR100145437(oga)
NPR108784409(MGEA5)
RTEM120946646(OGA)
BBUF121003921(OGA)
BGAR122941749(OGA)
MUO115461201 115470013(OGA)
GSH117358729(OGA) 117367430
DRE100538182(si:dkey-183c6.8) 324487(oga) 571547(ogal)
SRX107726775 107733669 107742283 107747552(mgea5) 107753935
SANH107666422 107667060 107668868 107691946 107700507
SGH107562569 107567635 107569412 107585241 107588144
CCAR109069987 109083210(mgea5)
CAUA113055552 113055557 113057088 113105718 113111272 113112823
CGIB127934348 127961040(si:dkey-183c6.8) 127967902 127970709 128021947 128026333
PTET122347855(si:dkey-183c6.8) 122353940(ogal) 122356819(oga)
LROH127168460(si:dkey-183c6.8) 127173249(ogal) 127175658(oga)
OMC131544988(si:dkey-183c6.8) 131549398(ogal) 131551807(oga)
PPRM120462600(si:dkey-183c6.8) 120479772(oga) 120491971(ogal)
RKG130076618(ogal) 130102702(si:dkey-183c6.8) 130102913(oga)
MAMB125256134(ogal) 125264490(si:dkey-183c6.8) 125276537(oga)
CIDE127516482(si:dkey-183c6.8) 127522866 127524623
CERY137020342(oga) 137021340(ogal) 137030365(si:dkey-183c6.8)
MASI127412440 127413966 127426483 127440801(si:dkey-183c6.8) 127450333
TROS130558892(oga) 130561474(si:dkey-183c6.8) 130571387(ogal)
TDW130410135(ogal) 130427255(si:dkey-183c6.8) 130431310(oga)
MANU129416693(oga) 129427560(ogal) 129440185(si:dkey-183c6.8)
IPU108263439(oga) 108267925(si:dkey-183c6.8) 108270888(ogal)
IFU128605458(oga) 128610243(si:dkey-183c6.8) 128613291(ogal)
PHYP113536642 113537792(oga) 113540315
SMEO124387264(si:dkey-183c6.8) 124391245(ogal) 124400441(oga)
TFD113644933(oga) 113653429(ogal) 113663159(si:dkey-183c6.8)
TVC132847166(oga) 132848824(si:dkey-183c6.8) 132855851(ogal)
TRN134311683(si:dkey-183c6.8) 134315083(oga) 134331258(ogal)
AMEX103032082(oga) 103039791(ogal) 103046573(si:dkey-183c6.8)
CMAO118810260(oga) 118818845(ogal) 118826561(si:dkey-183c6.8)
EEE113578274 113585838(oga) 113589695
CHAR105896616(si:dkey-183c6.8) 105910134(ogal) 122129963(oga)
TRU101062608(oga) 101067324 105418539 105419290
TFS130522742(si:dkey-183c6.8) 130527298(ogal) 130533658(oga)
TNGGSTEN00030608G001 GSTEN00032524G001
LCO104922274(oga) 104925209
NCC104950187 104955157(mgea5) 104955566
TBEN117474668(ogal) 117487949(si:dkey-183c6.8) 117499533(oga)
CGOB115010304 115019889(oga) 115023625
PGEO117458140(ogal) 117460205(oga) 117463660(si:dkey-183c6.8)
GACU117536760(oga) 117547240(si:dkey-183c6.8) 117561721(ogal)
EMAC134859239(oga) 134864819(ogal) 134875885(si:dkey-183c6.8)
ELY117248314(oga) 117255350(ogal) 117272795(si:dkey-183c6.8)
EFO125884337(si:dkey-183c6.8) 125885650(ogal) 125903250(oga)
PLEP121941846(ogal) 121954223(oga) 121962152(si:dkey-183c6.8)
SLUC116042246(si:dkey-183c6.8) 116042595(ogal) 116053576(oga)
ECRA117934563(si:dkey-183c6.8) 117936653(ogal) 117960762(oga)
ESP116704963 116705213(oga) 116707043
PFLV114570775 114571885(oga) 114573956
GAT120820615(oga) 120822207(si:dkey-183c6.8) 120825243(ogal)
PPUG119214134(oga) 119218258(ogal) 119222545(si:dkey-183c6.8)
AFB129092820(oga) 129093674(si:dkey-183c6.8) 129096114(ogal)
CLUM117737318 117737360 117743625(oga) 117747788(si:dkey-183c6.8)
PSWI130190707(ogal) 130207008(oga) 130211660(si:dkey-183c6.8)
MSAM119899547(ogal) 119912245 119917666(oga)
SCHU122870494(si:dkey-183c6.8) 122873977(ogal) 122883955(oga)
CUD121504818(si:dkey-183c6.8) 121508370(ogal) 121511590(oga)
ALAT119021638(ogal) 119027865(si:dkey-183c6.8) 119033510(oga)
ASTR137590580(si:dkey-183c6.8) 137599801(ogal) 137603361(oga)
MZE101471567 101472149(oga) 101474519
ONL100699721 100706413 100709857(oga)
OAU116319631(oga) 116322277(si:dkey-183c6.8) 116330977(ogal)
OLA101163611 101166655(mgea5) 101172880
OML112137423(ogal) 112155772(si:dkey-183c6.8) 112161614(oga)
CSAI133420374(si:dkey-183c6.8) 133444716(ogal) 133464034(oga)
XMA102223372 102231453 102232442(mgea5)
XCO114138448(oga) 114144358 114157373
XHE116713837(oga) 116719744 116733219
PRET103465403 103476931(mgea5) 103480785
PFOR103131168 103150495 103152236(mgea5)
PLAI106948276 106951257(mgea5) 106961065
PMEI106904343 106907807 106917533(mgea5)
GAF122820190(si:dkey-183c6.8) 122829586(ogal) 122842221(oga)
PPRL129359674(oga) 129366804(ogal) 129373293(si:dkey-183c6.8)
CVG107086606(mgea5) 107090773 107096471 107099030
CTUL119772716(si:dkey-183c6.8) 119783282(ogal) 119790729(oga)
GMU124859670(oga) 124867952(ogal) 124881277(si:dkey-183c6.8)
NFU107375656(mgea5) 107376946 107392405
KMR108234080(oga) 108236421(ogal) 108242892(si:dkey-183c6.8)
ALIM106521436 106525001 106535674(mgea5)
NWH119411948(oga) 119416968(si:dkey-183c6.8) 119422833(ogal)
AOCE111578864(mgea5) 111581963 111585373
MCEP124995892(si:dkey-183c6.8) 125003797(ogaL) 125019184(oga)
CSEM103383859 103387380(mgea5)
POV109627221 109633895(mgea5) 109634891
SSEN122766735(si:dkey-183c6.8) 122771484(ogal) 122781668(oga)
HHIP117751790(si:dkey-183c6.8) 117767478(ogal) 117775389(oga)
HSP118102410(si:dkey-183c6.8) 118114720(ogal) 118118701(oga)
PPLT128430488(si:dkey-183c6.8) 128437057(ogal) 128453032(oga)
SMAU118284234(oga) 118300895(si:dkey-183c6.8) 118313141(ogal)
LCF108875631 108888297(oga) 108888756(si:dkey-183c6.8)
SDU111229432 111231335 111234087(mgea5)
SLAL111657301(mgea5) 111666433 111666684
XGL120796260(oga) 120797482(si:dkey-183c6.8) 120800240(ogal)
HCQ109511913 109512679(mgea5) 109527421
SSCV125966956(si:dkey-183c6.8) 125968601
SBIA133494455(si:dkey-183c6.8) 133505560(ogal) 133510242(oga)
PEE133398003(si:dkey-183c6.8) 133403945(ogal) 133409493(oga)
PTAO133472792(si:dkey-183c6.8) 133485422(oga)
BPEC110156792(mgea5) 110165196 110174701
MALB109952730 109957845 109961022(mgea5)
BSPL114842102(oga) 114851042 114865352(ogal)
SJO128372675(oga) 128375491(ogal) 128383844(si:dkey-183c6.8)
SASA106564358 106576856 106591477 106604352(mgea5) 106609082
STRU115147542 115152980(oga) 115184176 115194036 115198612
OTW112214489(si:dkey-183c6.8) 112242091(ogal) 112252425(oga) 112252769
OMY110485509(ogal) 110493422 110500330(si:dkey-183c6.8) 110502247(oga) 110526041
OGO124014489(si:dkey-183c6.8) 124027507 124038090(oga) 124041468
ONE115113408(oga) 115133304 115135339
OKI109877382 109888932 109896844 109899564(oga)
OKE118369471 118392236(si:dkey-183c6.8) 118402305 127931946(ogal)
SALP111951659 111951809 111977735(mgea5)
SNH120017500 120018110 120041436 120046445(oga) 120049052(si:dkey-183c6.8)
CCLU121534281(ogal) 121553616 121568515(oga) 121571252(si:dkey-183c6.8)
ELS105010738(oga) 105012043 105031421
SFM108920620 108930276(oga)
PKI111846625(mgea5) 111849569 111857372
AANG118217811(oga) 118218961 118231584(si:dkey-183c6.8)
LOC102683302 102694479(mgea5)
PSPA121294585(si:dkey-183c6.8) 121321684 121325549
ARUT117409458(si:dkey-183c6.8) 117415414 117418184
PSEX120527964(si:dkey-183c6.8) 120542659(oga)
LCM102346400(MGEA5) 102358152
CMK103190567(oga)
RTP109923289(oga)
CPLA122550812(si:dkey-183c6.8) 122561283(oga)
HOC132823615(si:dkey-183c6.8) 132826341(oga)
LERI129703846(oga) 129715035(si:dkey-183c6.8) 129715818
PMRN116941422(OGA)
LRJ133345429 133345437
BFO118413805
BBEL109471441
CIN100179919
SCLV120338667
SPU585537
LPIC129273539
APLC110981261
ARUN117294835
AJC117118807
SKO100378403
DMEDmel_CG5871(Oga)
DER6553422
DSE6620036
DSIDsimw501_GD19407(Dsim_GD19407)
DYADyak_GE25717
DAN6494447
DSR110188182
DPO4800850
DPE6598788
DMN108154237
DWI6647454
DGR6567353
DMODmoj_GI21938
DAZ108608693
DNV108652629
DHE111602671
DVI6634891
CCAT101450686
BOD106617257
BDR105223133
RZE108370135 108374885
AOQ129236416
TDA119683232
MDE101893356
SCAC106084367
LCQ111688191
LSQ119601267 119606694
GFS119638827
ECOE129942630
CLON129611793
HIS119652242
AGA1269264
ACOZ120951771
AARA120908619
AMER121589718
ASTE118503564
AFUN125765765
AMOU128299171
AALI118460663
AAG5571796
AALB109410078 115253996 115257574
ASUA134204957
CQUCpipJ_CPIJ004076 CpipJ_CPIJ014846
CPII120416025
CNS116346932
BCOO119067420
LLL129787185
AME411905
ACER108000941
ALAB122711783
ADR102677664
AFLR100866448
BIM100749208
BBIF117215870
BVK117238281
BVAN117160087
BTER100645450
BAFF126924931
BPYO122569957
BPAS132914113
FVI122533387
CCAL108624654
OBB114878167
OLG117607908
MGEN117224355
NMEA116429460
CGIG122396249
SOC105196907
MPHA105835235
AEC105154917
ACEP105618479
PBAR105430117
VEM105563901
HST105189349
DQU106747473
CFO105248789
FEX115237312
LHU105675868(Oga)
PGC109860249
OBO105281645
PCF106793487
PFUC122516433
VPS122628814
VCRB124424749
VVE124948590
NVI100119788
CSOL105360693
TPRE106652648
LHT122505723
LBD127291442
MDL103571170
CGLO123263502
FAS105270416
DAM107038060
AGIF122851854
CINS118072729
VCAN122406983
CCIN107267294
DSM124414604
NPT124222732
NFB124187111
NLO107226158
NVG124308978
AROA105688301
TCA655306
DPA109539113
SOY115890736
AGRG126741964
ATD109597139
CSET123313140
AGB108904637
LDC111511864
DVV114331269
NVL108558025
APLN108744311
PPYR116175725
OTU111423601
BMOR101735953
BMAN114253038
MSEX115451650
DPLKGM_213232
BANY112055407
MJU123877874
NIQ126778089
VCD124539766
MCIX123665067
PMAC106719051
PPOT106102929
PXU106116405
PRAP110998763
PBX123719138
PNAP125054643
ZCE119837823
CCRC123702769
LSIN126977224
AAGE121737677
HAW126056306 135118345
HZE124641831
TNL113507217
OFU114350222
ATRA106130756
GMW113514282
PXY105384531
PGW126377262
CFEL113375574 113378687
CCRN123290602
API100163269
DNX107165302
AGS114131204
RMD113554292
ACOO126843749
DVT126900493
BTAB109033140
DCI103512952 103519672
CLEC106662476
HHAL106678327(Oga)
NLU111047189 120354001
HVI124359468
MQU128993438
PHUPhum_PHUM456250
FOC113207022
TPAL117653219
ZNE110832426
CSEC111873810
SGRE126355425
BROR134539333
IEL124154108
FCD110863215
DPXDAPPUDRAFT_312251
PVM113822939 113822940
PJA122252320
PCHN125035764
PMOO119593991
HAME121864984
PCLA123761787
CQD128690157
PTRU123516737
ESN127010085
MNZ135207539
MRJ136850801(Oga)
HAZT108679419
EAF111700900
LSM121113819
TCF131881583 131891206
PPOI119111677
ISC8042980
DSV119459137
RSAN119379212
RMP119175846
VDE111254346
VJA111270765
TUT107360407
DPTE113788567
DFR124489927
CSCU111615007 111636175
CVS136976671(Oga)
PTEP107442614
ABRU129960188
UDV129219369
SDM118189878
LPOL106462405 106463687
PMEO129589081
BMYBM_BM5855(Bma-oga-1)
LOALOAG_17941
HROHELRODRAFT_194783
LGILOTGIDRAFT_115468
PVUL126815731
PCAN112563760 112564338
BGT106065918
GAE121384746
HRF124141247
HRJ124267293
CRG105347264
CANU128169083
CVN111101889
OED125659345
MYI110449102
PMAX117339865
MCAF127732956
MMER123547436
RPHI132731622
DPOL127841352 127875973
MAEA128211118 128211261
OBI106884279
OSN115218926
LJP135466502
LAK106176558
SMMSmp_000020 Smp_210490
SHXMS3_00001585(MGEA5_1)
OVIT265_08710
EGLEGR_04224
LLON135488902
NVE5519790
EPA110245582
ATEN116292862
ADF107327833
AMIL114973993
PDAM113667448
SPIS111320587
DGT114515726
XEN124444197
HMG100215737
HSY130644382 130644801
RES135685138 135695916
AQU100640131
SREPTSG_03030
ACANACA1_069750
 » show all
Reference
1  [PMID:11148210]
  Authors
Gao Y, Wells L, Comer FI, Parker GJ, Hart GW
  Title
Dynamic O-glycosylation of nuclear and cytosolic proteins: cloning and characterization of a neutral, cytosolic beta-N-acetylglucosaminidase from human  brain.
  Journal
J Biol Chem 276:9838-45 (2001)
DOI:10.1074/jbc.M010420200
  Sequence
[hsa:10724]
Reference
2  [PMID:11788610]
  Authors
Wells L, Gao Y, Mahoney JA, Vosseller K, Chen C, Rosen A, Hart GW
  Title
Dynamic O-glycosylation of nuclear and cytosolic proteins: further characterization of the nucleocytoplasmic beta-N-acetylglucosaminidase, O-GlcNAcase.
  Journal
J Biol Chem 277:1755-61 (2002)
DOI:10.1074/jbc.m109656200
  Sequence
[hsa:10724]
Reference
3  [PMID:16533067]
  Authors
Cetinbas N, Macauley MS, Stubbs KA, Drapala R, Vocadlo DJ
  Title
Identification of Asp174 and Asp175 as the key catalytic residues of human O-GlcNAcase by functional analysis of site-directed mutants.
  Journal
Biochemistry 45:3835-44 (2006)
DOI:10.1021/bi052370b
Reference
4  [PMID:16565725]
  Authors
Dennis RJ, Taylor EJ, Macauley MS, Stubbs KA, Turkenburg JP, Hart SJ, Black GN, Vocadlo DJ, Davies GJ
  Title
Structure and mechanism of a bacterial beta-glucosaminidase having O-GlcNAcase activity.
  Journal
Nat Struct Mol Biol 13:365-71 (2006)
DOI:10.1038/nsmb1079
  Sequence
[bth:BT_4395]
Reference
5  [PMID:16584714]
  Authors
Kim EJ, Kang DO, Love DC, Hanover JA
  Title
Enzymatic characterization of O-GlcNAcase isoforms using a fluorogenic GlcNAc substrate.
  Journal
Carbohydr Res 341:971-82 (2006)
DOI:10.1016/j.carres.2006.03.004
Reference
6  [PMID:8034696]
  Authors
Dong DL, Hart GW
  Title
Purification and characterization of an O-GlcNAc selective N-acetyl-beta-D-glucosaminidase from rat spleen cytosol.
  Journal
J Biol Chem 269:19321-30 (1994)
  Sequence
[rno:154968]
Other DBs
ExplorEnz - The Enzyme Database: 3.2.1.169
IUBMB Enzyme Nomenclature: 3.2.1.169
ExPASy - ENZYME nomenclature database: 3.2.1.169
BRENDA, the Enzyme Database: 3.2.1.169

DBGET integrated database retrieval system