KEGG   ENZYME: 3.2.1.206Help
Entry
EC 3.2.1.206                Enzyme                                 

Name
oleuropein beta-glucosidase;
OeGLU (gene name)
Class
Hydrolases;
Glycosylases;
Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
BRITE hierarchy
Sysname
oleuropein 2-beta-D-glucohydrolase
Reaction(IUBMB)
oleuropein + H2O = oleuropein aglycone + D-glucopyranose [RN:R11942]
Reaction(KEGG)
Substrate
oleuropein [CPD:C09794];
H2O [CPD:C00001]
Product
oleuropein aglycone [CPD:C21786];
D-glucopyranose [CPD:C00031]
Comment
Oleuropein is a glycosylated secoiridoid exclusively biosynthesized by members of the Oleaceae plant family where it is part of a defence system againt herbivores. The enzyme also hydrolyses ligstroside and demethyloleuropein.
History
EC 3.2.1.206 created 2017
Orthology
K22425  oleuropein beta-glucosidase
Genes
OEU: 111404214
Taxonomy
Reference
1  [PMID:16349442]
  Authors
Ciafardini G, Marsilio V, Lanza B, Pozzi N
  Title
Hydrolysis of Oleuropein by Lactobacillus plantarum Strains Associated with Olive Fermentation.
  Journal
Appl Environ Microbiol 60:4142-7 (1994)
Reference
2  [PMID:19689134]
  Authors
Romero-Segura C, Sanz C, Perez AG
  Title
Purification and characterization of an olive fruit beta-glucosidase involved in  the biosynthesis of virgin olive oil phenolics.
  Journal
J Agric Food Chem 57:7983-8 (2009)
DOI:10.1021/jf901293c
Reference
3  [PMID:22475562]
  Authors
Gutierrez-Rosales F, Romero MP, Casanovas M, Motilva MJ, Minguez-Mosquera MI
  Title
beta-Glucosidase involvement in the formation and transformation of oleuropein during the growth and development of olive fruits (Olea europaea L. cv. Arbequina) grown under different farming practices.
  Journal
J Agric Food Chem 60:4348-58 (2012)
DOI:10.1021/jf205209y
Reference
4  [PMID:25697790]
  Authors
Koudounas K, Banilas G, Michaelidis C, Demoliou C, Rigas S, Hatzopoulos P
  Title
A defence-related Olea europaea beta-glucosidase hydrolyses and activates oleuropein into a potent protein cross-linking agent.
  Journal
J Exp Bot 66:2093-106 (2015)
DOI:10.1093/jxb/erv002
  Sequence
Reference
5  [PMID:28483880]
  Authors
Koudounas K, Thomopoulou M, Michaelidis C, Zevgiti E, Papakostas G, Tserou P, Daras G, Hatzopoulos P
  Title
The C-Domain of Oleuropein beta-Glucosidase Assists in Protein Folding and Sequesters the Enzyme in Nucleus.
  Journal
Plant Physiol 174:1371-1383 (2017)
DOI:10.1104/pp.17.00512
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 3.2.1.206
IUBMB Enzyme Nomenclature: 3.2.1.206
ExPASy - ENZYME nomenclature database: 3.2.1.206
BRENDA, the Enzyme Database: 3.2.1.206

  All links  
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (2)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
All databases (11)   

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