Hydrolases;
Glycosylases;
Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
BRITE hierarchy

oleuropein 2-beta-D-glucohydrolase

oleuropein + H2O = oleuropein aglycone + D-glucopyranose [RN:R11942]

R11942
Reaction

oleuropein [CPD:C09794];
H2O [CPD:C00001]

Oleuropein is a glycosylated secoiridoid exclusively biosynthesized by members of the Oleaceae plant family where it is part of a defence system againt herbivores. The enzyme also hydrolyses ligstroside and demethyloleuropein.

EC 3.2.1.206 created 2017

1  [PMID:16349442]

Ciafardini G, Marsilio V, Lanza B, Pozzi N

Hydrolysis of Oleuropein by Lactobacillus plantarum Strains Associated with Olive Fermentation.

Appl Environ Microbiol 60:4142-7 (1994)
DOI:10.1128/AEM.60.11.4142-4147.1994

2  [PMID:19689134]

Romero-Segura C, Sanz C, Perez AG

Purification and characterization of an olive fruit beta-glucosidase involved in  the biosynthesis of virgin olive oil phenolics.

J Agric Food Chem 57:7983-8 (2009)
DOI:10.1021/jf901293c

3  [PMID:22475562]

Gutierrez-Rosales F, Romero MP, Casanovas M, Motilva MJ, Minguez-Mosquera MI

beta-Glucosidase involvement in the formation and transformation of oleuropein during the growth and development of olive fruits (Olea europaea L. cv. Arbequina) grown under different farming practices.

J Agric Food Chem 60:4348-58 (2012)
DOI:10.1021/jf205209y

4  [PMID:25697790]

Koudounas K, Banilas G, Michaelidis C, Demoliou C, Rigas S, Hatzopoulos P

A defence-related Olea europaea beta-glucosidase hydrolyses and activates oleuropein into a potent protein cross-linking agent.

J Exp Bot 66:2093-106 (2015)
DOI:10.1093/jxb/erv002

[ag:AAL93619]

5  [PMID:28483880]

Koudounas K, Thomopoulou M, Michaelidis C, Zevgiti E, Papakostas G, Tserou P, Daras G, Hatzopoulos P

The C-Domain of Oleuropein beta-Glucosidase Assists in Protein Folding and Sequesters the Enzyme in Nucleus.

Plant Physiol 174:1371-1383 (2017)
DOI:10.1104/pp.17.00512

[ag:AAL93619]