KEGG   ENZYME: 3.2.1.225
Entry
EC 3.2.1.225                Enzyme                                 
Name
D-arabinan exo alpha-(1,3)/(1,5)-arabinofuranosidase (non-reducing end);
exo-alpha-D-arabinofuranosidase;
DgGH172a;
DgGH172b;
DgGH172c;
NocGH172;
MycGH172;
ExoMA1
Class
Hydrolases;
Glycosylases;
Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
Sysname
alpha-D-arabinofuranoside non-reducing end alpha-D-arabinofuranosidase (configuration-retaining)
Reaction(IUBMB)
Hydrolysis of terminal non-reducing alpha-D-arabinofuranoside residues in D-arabinans
Comment
The enzyme hydrolyses alpha-D-arabinofuranosides with (1->3)- and (1->5)-linkages in D-arabinan core structure of lipoarabinomannan and arabinogalactan of mycobacterial cell wall. cf. EC 3.2.1.55, non-reducing end alpha-L-arabinofuranosidase; EC 3.2.1.224, D-arabinan exo beta-(1,2)-arabinofuranosidase (non-reducing end); and EC 3.2.1.226, D-arabinan endo alpha-(1,5)-arabinofuranosidase.
History
EC 3.2.1.225 created 2024
Orthology
K27494  D-arabinan exo alpha-(1,3)/(1,5)-arabinofuranosidase (non-reducing end)
Genes
NVE5511766
ADF107350488 107354230
AMIL114968589 114968675 114970562
DGT114517388
XEN124454523 124455676
HMG100205240
HSY130623386
AQU109581954 109591276
PGUPGUG_03952
TTTTHITE_2118009
TMNUCRPA7_5218
SSCKSPSK_02518
FOXFOXG_17518
NHENECHADRAFT_48881
FFCNCS54_01193800
FKRNCS57_01185300
PCHMVFPPC_10672 VFPPC_14047
PLJ28885117(PLICBS_006289) 28892387(PLICBS_000153) 28892581(PLICBS_006393)
PTKZJDV02_008174 JDV02_008270
CFJCFIO01_13533
CLUPCLUP02_01757
CDET87943764(CDEST_07261)
ANIANIA_07098
AFMAFUA_5G00510
NFINFIA_042000
ANGAn06g02400
PCSN7525_011241
TRGTRUGW13939_07069
MBRMONBRDRAFT_21825
KOCAB185_28505
KLLBJF97_07975
LAZA8A57_04775
SUPEP0H77_06030
CARUP0E69_21905
NIGC1N62_04155
XBCELE36_17335
WOCBA177_04515 BA177_05115
EMPEZMO1_0729
GAPGAPWK_2250
GAQRAM11_03685
FPPFPB0191_00080
VEIVeis_0526
MOPMesop_5939
SMESM_b20234
SMKSinme_3939
SMQSinmeB_4436
SMXSM11_pD1377
SMIBN406_06432
SMEGC770_GR4pD1363
SMELSM2011_b20234
SMERDU99_32200
SMDSmed_2312
EAKEKH55_4575
EMXFKV68_26695
ENUPYH37_001709 PYH37_001714
EGIPZN02_004225 PZN02_004728
STEGQA637_25420
RHLLPU83_pLPU83d1860
RJGCCGE525_09395
RHRCKA34_31565
RHIBI8E17_29440
BJUBJ6T_59890
BJPRN69_29015
BRSS23_43790
BRCBCCGELA001_16085
BOTCIT37_34635
BGQX265_24025
BGZXH91_21230
BDGLPJ38_21460
BBANJ4G43_021325
BCOUIC761_21785
BXNI3J27_15330
BRAZLRP30_16705
LNEFZC33_26280
DEQXM25_03865
DEIC4375_11760
DSALK1X15_18785
DNPN8A98_16310
DAGPSQ19_05350
DRPPSQ90_10580
YTIFNA67_07700
AALAIGS74_14265
PPAFI8N54_17080
SPHCCVN68_03030
SSAARPR59_08000 RPR59_08025
QCINCF85_08035
SKTIGS68_27525
SMUCJL100_029625
SROEJL101_028415
KOZKFF44_12880
GSOPH603_07325
DOLDole_0956
SCLsce3321
SCUSCE1572_50515
PAUUE8A73_021970
MRMA7982_05151
SAMYDB32_003035
LLUAKJ09_07871
BACQDOE78_08835
BCIRC2I06_01315
OONNP440_18020
GRCGI584_19230
MEKUHUW50_15430
BAGBcoa_1661
ALKGMOJ78_02695
PJDPjdr2_5449 Pjdr2_5939
GYMGYMC10_2578 GYMC10_2589 GYMC10_3781 GYMC10_3788
PTAHPL003_01845
PSABPSAB_20120
PDUPDUR_22770
PAENP40081_19380 P40081_19415 P40081_29695
PBJVN24_25605 VN24_25805
PRIPRIO_4903 PRIO_4911
PSONJI735_10065 JI735_32190
POWIJ21_02160
PBVAR543_03795
PSWUSY83_08675
PIBBBD41_01885 BBD41_01990
PLWD5F53_11295
PPSCEHS13_24155 EHS13_24160 EHS13_24225 EHS13_26480 EHS13_26560 EHS13_26825 EHS13_27685
PALBEJC50_00400 EJC50_06005 EJC50_16415 EJC50_21645 EJC50_29225
PCHIPC41400_10720
PRZGZH47_07935 GZH47_08785 GZH47_08840 GZH47_13600 GZH47_19400 GZH47_20110 GZH47_20155 GZH47_28645 GZH47_31170
PLYCGXP70_03030 GXP70_08460 GXP70_09680 GXP70_19010 GXP70_27185
PSOPKP014_26710
PTRIKDC22_17045 KDC22_17080
PAMYP9222_21140
PDYQJQ58_06090
PMAELMZ02_19240 LMZ02_19295
PSPNL1F29_01655 L1F29_09235 L1F29_11755 L1F29_16730 L1F29_18430
PAUNMJA45_13045 MJA45_18145
PHKSK066_05775
PPABKET34_05875 KET34_05890
PEZZHW560_21540
COHEAV92_13340 EAV92_13410
CHEBHH215_01890 HH215_08560 HH215_12770 HH215_14265 HH215_29595 HH215_29630
COHLJ4772_04540 J4772_20750 J4772_23150 J4772_23575 J4772_28880 J4772_30780
NTRB0W44_12555 B0W44_12600
LAPIDKL56_01035 DKL56_07400
LPAIGYM71_01735 GYM71_09800
LHWBSQ49_12450
LBMDS830_06095
LDXLH506_03380
EFCEFAU004_00682
EFAUEFAU085_00630
EFUHMPREF0351_10291 HMPREF0351_10708
EAVEH197_03140 EH197_08865 EH197_19965
ESGEsVE80_18350
FCTNRE15_05065 NRE15_12885
CBECbei_3498
CBZCbs_3498
CDYF3K33_17730
CNNCNEO_1561
CTHDCDO33_03955
FSAC5Q98_04310 C5Q98_06890 C5Q98_06900
RUKA4V00_03570
FPRACG447_03065
FDUGXM22_05830
FTKPXT33_012880
AMURADH66_05430
RIXRO1_04400
RIMROI_12140
ROBCK5_01060 CK5_01120
BYLA4V09_21455
BPROPMF13cell1_00339 PMF13cell1_01147 PMF13cell1_01861
BLABEYS05_11350
BLIQINP51_02665 INP51_02940 INP51_02970
BWXNQ550_04860
BMASLK422_12320
BLARLC508_14615 LC508_20855 LC508_21830
BLUIBlut17040_05320
BCOCBLCOC_09170 BLCOC_51030 BLCOC_53430
CSCIHDCHBGLK_03487
LUAD4A81_00205
LGGQJR73_13160
ANRAna3638_02555 Ana3638_09795
ACHTbsdcttw_21700
RTORTO_14380
RGNRGna_09050
DLOK5I24_09115
MFORNQ534_12810
EREEUBREC_0286 EUBREC_3517
ERTEUR_31840
ERAERE_00380 ERE_19410
CBILEUBC25_02650
TTOThethe_00435
MASMahau_0700
HALSD7D81_18150 D7D81_18155
IFNGM661_14770 GM661_14775
CMITNQ499_10270
LPILLIP_2038
FBSN510_000690
MPAMAP_0339c
MAOMAP4_3531
MAVIRC58_17540
MAVURE97_17575
MAVMAV_0365
MITOCO_03200
MIAOCU_03280
MIDMIP_00687
MYOOEM_03320
MCHIAN480_01635
MIROCQ_03230
MMALCKJ54_01535
MMANMMAN_45770
MSERMTY59_22040
MMMW7S_01575
MSHGMSG_01425
MXEMYXE_24180 MYXE_32280
MNVMNVI_24420
MSEOMSEO_36790
MHEKJMUB5695_02341 JMUB5695_03230
MBRDMBRA_38030
MMAMK3U93_21935
MMEHM5I08_17195
NBRO3I_017420
NNONONO_c18400
NSRNS506_06814
NTPCRH09_10350 CRH09_21400
NOZDMB37_16180 DMB37_39080
NAHF5544_20220
NWLNWFMUON74_53990
NTCKHQ06_35245
NHUH0264_34375
NYALTV02_38570
NGPLTT66_36200
NSPUIFM12276_37540
NYUD7D52_09595
SMALSMALA_6791 SMALA_7996
SSOII1A49_37720 I1A49_43700
SDVBN159_0193
SALSSLNWT_6169 SLNWT_7198
STRCAA958_08245 AA958_19865
SPRISPRI_0909
STRDNI25_02900
SAUOBV401_37550
SASTCD934_32625
SBATG4Z16_01670
SFEUIM697_22255
SPEUCGZ69_03155 CGZ69_03170
STUBMMF93_32090
SLONLGI35_41685
SCOAQU709_45770
SARMDVA86_25505
SLUOPS467_37870
SCAJO1G22_41045
LEIFHF024_18140
MIOAOA12_07045
MCWA8L33_02660
MFOLDXT68_15640
MWAE4K62_17895
MPRTET475_04985
MOYCVS54_03478
MLZF6J85_17000
MRNK8F61_14735
MAZANFX31_16065
MSUFKV394_03870
RTNA6122_1315
RRYC1O28_13155
RFSC1I64_06665
FSBGCM10025867_36410
AARCG127AT_08370
AILFLP10_14905
HUWFPZ11_15350
MANTBHD05_02530
HEHL3i23_22020
NAEIGCM126_20620
ARIUM93_01735
ACHAchl_4615
BCVBcav_1697 Bcav_1706
BRXBH708_16840
BGGCFK41_13950
BKIM4486_17155
BRHANLU66_17615
BHHBra3105_13870
BHQBRM3_01395
LMOIVV02_12665 VV02_16540
CELCK5O09_00775
CELEP9841_10125
PEIH9L10_00400
HALTIM660_11230 IM660_18690
RHALLQF10_10845 LQF10_18330 LQF10_18375
RSUALQF12_01490
PBOPACID_30190
AACIASQ49_07055
ACIJJS278_00348
MPHMLP_04200
MIKFOE78_16460
MICGGJV80_13020 GJV80_18715
TESBW730_09545
TDFH9L22_14135
NCANoca_0057
SGRGL0C25_02255 L0C25_21200
KFLKfla_1880 Kfla_2842
KQIF1D05_29155 F1D05_34720
KSLOG809_12245 OG809_19930 OG809_27280
KRIOX958_21935
ACTQOG417_21435
NOWGBF35_30775 GBF35_30790
FREFranean1_7052
SENSACE_0944 SACE_2137
SACGFDZ84_00560 FDZ84_02430 FDZ84_16595
AMQAMETH_1580 AMETH_5365
AACDLWP59_07960 LWP59_15895
ATHML1857_10550 L1857_29795
ACYNORV05_17340
AMYZHUW46_07091
PSDSK1T35_24815
KALKALB_1788
KUTJJ691_23420
KPHYAOZ06_41090
SACEGIY23_03970 GIY23_09395
ACTYOG774_21350
MILML5_4285
MICBMicB006_5001
MTUACSH63_14990
MTEMGCE86_08490
MPRNQ3V37_27780
MHAWRMN56_29955
PLKCIK06_05645
ATLAthai_32740
ASERAsera_41910
DACTKZZ52_31355
SNASnas_3124 Snas_3258
BLJBLD_0908 BLD_1491
BLNBlon_0046
BLONBLIJ_0046
BLLBLJ_1995
BLBBBMN68_912
BLMBLLJ_0461 BLLJ_1877
BLKBLNIAS_02101 BLNIAS_02937
BLGBIL_13830
BLZBLGT_03120
BADBAD_1588
BADLBADO_1694
BADOBBMN23_1762
BDEBDP_2163 BDP_2171
BDNBBDE_2032 BBDE_2040
BBRUBbr_0030 Bbr_1861
BBREB12L_1799
BBRJB7017_0039
BBRCB7019_2052
BBRSBS27_0038
BASTBAST_0334 BAST_1636
BCORBCOR_0277
BIIBINDI_0214
BKAAH68_09590
BKSBBKW_1875
BCATBBCT_1571 BBCT_1607
BANGBBAG_0439
BPSCBBPC_1677
BSCABBSC_2504
BGXESN35_02395
BLEMBL8807_03690
BEUBE0216_08370
BFJB19861_18280
SIJSCIP_0372
AEYCDG81_18140
RUBGBA63_16980
LMAJGKN94_11140
RRSRoseRS_2835
RCARcas_2768
CALLOZ401_000185 OZ401_000864
ABATCFX1CAM_1986
ABAOBEQ56_10230
CAPCLDAP_18720
KBSEPA93_23005
TTRTter_0622
PMETG4Y79_06430
DPDDeipe_1359
DMBE5F05_00835
CCZCCALI_00630 CCALI_02654
FGIOP10G_0366 OP10G_0633 OP10G_1344 OP10G_1487 OP10G_2091 OP10G_2798 OP10G_3516 OP10G_4487 OP10G_4808
NPYNPRO_01100 NPRO_09310 NPRO_13160 NPRO_17100
CCOTCCAX7_007310 CCAX7_41300
OTEOter_3336
OLEK0B96_05115
ELUTCKA38_01365 CKA38_01545
AAQWK1X11_014440
TMVOH491_02170 OH491_03775 OH491_18090
CALGSH580_01710
PUORZN69_00100 RZN69_14250 RZN69_15685 RZN69_20080
LUOHHL09_04820 HHL09_23865
VEGSAMN05444156_3178
FPESNXS98_01335 NXS98_02995 NXS98_08235 NXS98_10525
VBSEGM51_07940
MFFMFFC18_48150
AHELQ31a_41490
AAGGETAA8_16750
SNEPEnr13x_09610
TTFTHTE_0699 THTE_4099 THTE_4165
AMUCPan181_51430
PNDPla175_30480 Pla175_30490
AMOBHG15A2_17030 HG15A2_17040 HG15A2_43250
BMEISpa11_22390 Spa11_25410
PLHVT85_24900
GAWV144x_13410
CCOPMal65_32010
PBORBSF38_01516 BSF38_02944 BSF38_03509
AGVOJF2_26270 OJF2_26860 OJF2_34730 OJF2_45230 OJF2_56740 OJF2_74770 OJF2_74890 OJF2_74900 OJF2_74920
PCORKS4_24870
MCADPan265_12730
PBUL21SP3_01635
PBPSTSP1_01648
PBASSMSP2_00767 SMSP2_01913 SMSP2_01922 SMSP2_01961 SMSP2_02222
VBLL21SP4_01796
TAERGT409_00860
VBCC5Q97_00790
SCCSpico_0498
TAZTREAZ_2028
BHCJFL75_02760 JFL75_15860 JFL75_15865
LBILEPBI_I3383
LBFLBF_3269
LKBLPTSP3_g35250
TALBFTW19_07950
ABASACPOL_5317 ACPOL_7173 ACPOL_7178
EDAGWR55_11120
EDGH7846_07095
EPLP4G45_02505
ADINH7849_02605
ORPMOP44_00160 MOP44_21025
TEMPRBB75_13460
TPSCRBB77_05525
SUSAcid_0831
PFERIRI77_03600 IRI77_20605 IRI77_29325 IRI77_34035
ABACLuPra_01197 LuPra_02560
LUBTBR22_A11450
GBAJ421_2137
BFRBF4284 BF4528
BFSBF9343_3982 BF9343_4210
BFGBF638R_4141 BF638R_4481
BFBVU15_19745 VU15_21040
BXYBXY_21080
BOABovatus_03046
BCELBcellWH2_03056
BISDXK01_004630 DXK01_004705 DXK01_004710
BUNBun01g_05090 Bun01g_05100 Bun01g_08130 Bun01g_08210 Bun01g_08310 Bun01g_08350 Bun01g_08380 Bun01g_17010 Bun01g_18160 Bun01g_19070
BFEK6V30_00845 K6V30_00855
BNOK8P02_12640
BHUMJXR92_004610
BSALK6V25_19820
PBTING2E5B_1386 ING2E5B_2253
PMUCING2E5A_0263 ING2E5A_1581
PETPEIBARAKI_4034 PEIBARAKI_4041 PEIBARAKI_4042
PSACPSM36_0007 PSM36_0014 PSM36_0015 PSM36_3154
PDIBDI_2465
PARCCI960_18575
PFAINXY11_00585
COPRCop2CBH44_30650
PHERprwr041_13200
PBUCLK429_02055 LK429_04690 LK429_04710
AFDAlfi_2406
ALDGFH31_01940
ADAA5CPEGH6_11540
AITAI2BBH_03480
ASENNQ519_12400
MCOSGM418_02430 GM418_10305 GM418_27615 GM418_28000
CPICpin_1790
CHIHGWR21_24380
COYHF329_03540
CFILMYF79_09000
CHFKTO58_11100
CHORMKQ68_14235
CSACSIO70_10335
CPOLWJU16_05840
CHIMCK934_17795
NSONIASO_00510 NIASO_04895
NIAA8C56_12240 A8C56_13070 A8C56_13080 A8C56_13460 A8C56_13480 A8C56_13485 A8C56_13520 A8C56_18715
NYNU0035_13780 U0035_13790
NDFKRR40_16540 KRR40_16555 KRR40_18445
AGIFSB73_14190
ATEEK9M52_00205
PGINFRZ67_04840 FRZ67_21895
PGOFSB84_13135
FLSGLV81_00870
FLCKJS93_07945 KJS93_11455 KJS93_12190
THEOIMW88_03500
CBAMPIECOFPK_01784
HHYHalhy_0382 Halhy_0604
PGSCPT03_05790 CPT03_06660 CPT03_20380
PMUOLOK61_16245
SHGSph21_0614
SMIZ4412673_01333 4412673_02494
SPHZE3D81_06100
SDJNCTC13534_01556 NCTC13534_02086
STHANCTC11429_00385
MUCMuYL_3107
MGOTMgSA37_02347
MUHHYN43_020445
MGINFRZ54_12220 FRZ54_15320
MGKFSB76_16450
MRUBDEO27_020560
MGOSDIU38_021555
MSABSNE25_19230 SNE25_19250 SNE25_19255 SNE25_19290 SNE25_23305 SNE25_31440
OLIFKG96_21740 FKG96_26545
CAMUCA2015_2173
ESTDN752_22495
SRDSD10_01255
SMONAWR27_18380
FIBA6C57_16680
HYJFHG12_05930
HQIH9L05_04620
PKOPKOR_14010
PONTC1N53_12220
CLITOQ292_05575
FBTD770_23785
CHKD4L85_03080 D4L85_30070
FAXFUAX_07660 FUAX_25980 FUAX_46000 FUAX_47770
ATKAUTU_33110
GFLGRFL_0465
ZPRZPR_0900
ZGAZOBELLIA_3462
PUNNQP51_12140
WIJBWZ20_14355
AHZAPS56_06015
SALTAO058_17405 AO058_17440 AO058_17450 AO058_17485 AO058_17490 AO058_17515
FEKC1H87_02660
FLGLV716_14215
SPONHME9304_01956 HME9304_01957
PHYAJ81_06220
MPGTheba_1589
MINFMESINF_2411
ASACATHSA_0371
ALAMRT761_01354 RT761_01358 RT761_01361
MAMAGII36_05205
SBAGUW38_C0001G0591
FSHQ2T83_08945 Q2T83_15665
HRRHZS55_14600
CMACmaq_0234
LOKILokiarch_33310
LOBNEF87_002911
PSYTDSAG12_00869
 » show all
Reference
1  [PMID:37076525]
  Authors
Al-Jourani O, Benedict ST, Ross J, Layton AJ, van der Peet P, Marando VM, Bailey NP, Heunis T, Manion J, Mensitieri F, Franklin A, Abellon-Ruiz J, Oram SL, Parsons L, Cartmell A, Wright GSA, Basle A, Trost M, Henrissat B, Munoz-Munoz J, Hirt RP, Kiessling LL, Lovering AL, Williams SJ, Lowe EC, Moynihan PJ.
  Title
Identification of D-arabinan-degrading enzymes in mycobacteria.
  Journal
Nat Commun 14:2233 (2023)
DOI:10.1038/s41467-023-37839-5
  Sequence
[nbr:O3I_017420] [mama:GII36_05205]
Reference
2  [PMID:37726269]
  Authors
Shimokawa M, Ishiwata A, Kashima T, Nakashima C, Li J, Fukushima R, Sawai N, Nakamori M, Tanaka Y, Kudo A, Morikami S, Iwanaga N, Akai G, Shimizu N, Arakawa T, Yamada C, Kitahara K, Tanaka K, Ito Y, Fushinobu S, Fujita K.
  Title
Identification and characterization of endo-alpha-, exo-alpha-, and exo-beta-D-arabinofuranosidases degrading lipoarabinomannan and arabinogalactan of mycobacteria.
  Journal
Nat Commun 14:5803 (2023)
DOI:10.1038/s41467-023-41431-2
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 3.2.1.225
IUBMB Enzyme Nomenclature: 3.2.1.225
ExPASy - ENZYME nomenclature database: 3.2.1.225
BRENDA, the Enzyme Database: 3.2.1.225

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