KEGG ENZYME: 3.2.2.2

ENZYME: 3.2.2.2

Entry

EC 3.2.2.2                  Enzyme

Name

inosine nucleosidase;
inosinase;
inosine-guanosine nucleosidase

Class

Hydrolases;
Glycosylases;
Hydrolysing N-glycosyl compounds

Sysname

inosine ribohydrolase

Reaction(IUBMB)

inosine + H2O = D-ribose + hypoxanthine [RN:R01770]

Reaction(KEGG)

R01770

Substrate

inosine [CPD:C00294];
H2O [CPD:C00001]

Product

D-ribose [CPD:C00121];
hypoxanthine [CPD:C00262]

History

EC 3.2.2.2 created 1961

Pathway

ec00230

Purine metabolism

ec01100

Metabolic pathways

Orthology

K25589

inosine/uridine nucleosidase

Genes

CCAC:

CcaHIS019_0205560(rihB)

LMA:	LMJF_18_1580(NH)

LIF:	LINJ_18_1570(NH)

LDO:	LDBPK_181570

LMI:	LMXM_18_1580

LMAT:

92516717(LSCM1_06800)

LBZ:	LBRM_18_1610

LPAN:

LPMP_181530(NH)

LOI:	92362995(LSCM4_07157)

SMAR:

SM39_3857(iunH)

SMAC:

SMDB11_3635(iunH)

SMW:	SMWW4_v1c43630(rihB)

SPE:

Spro_4396

SRR:	SerAS9_4502

SRL:	SOD_c42040(rihB1)

SRY:	M621_22915(rihB)

SPLY:

Q5A_022895(rihB)

SRS:	SerAS12_4503

SRA:	SerAS13_4503

SLQ:	M495_22155(rihB)

SERF:

L085_06410

SERS:

SERRSCBI_21065

SFW:	WN53_04995(rihB)

SFG:	AV650_00420(rihB) AV650_27260(rihB)

SQU:	E4343_18785

SFJ:	SAMEA4384070_4366(rihB)

SOF:	NCTC11214_02275(rihB)

SSUR:

ATE40_018345(rihB)

SURI:

J0X03_02285

SENP:

KHA73_21290

SNEM:

NLX84_22330

SNEV:

OI978_09030

SGRI:

SGBXF1_04344(rihB_1)

SSAR:

SSARUM_004266

RAH:	Rahaq_1087

RACE:

JHW33_22150

RAQ:	Rahaq2_1158

RAA:

Q7S_05215

ROX:	BV494_00700(rihB)

RVC:	J9880_13250

RBON:

QNM34_05540

RIU:	I2123_07410

EAME:

GXP68_05725

PMAK:

PMPD1_2776

PLU:	plu4289(iunH)

PLUM:

A4R40_21265(rihB)

PAY:	PAU_00466(iunH)

PTT:	VY86_05035(rihB)

PAKH:

B0X70_02890(rihB)

PLUI:

CE143_02875(rihB)

XBO:	XBJ1_3558(rihB)

XBV:	XBW1_1138(IUNH)

XNE:	XNC1_3617(rihB)

XNM:	XNC2_3476(rihB)

XDO:	XDD1_0654(IUNH)

XPO:	XPG1_2860(IUNH)

XHO:	A9255_12230(rihB)

XBU:	HGO23_03120

XGR:	QL128_17690

PSI:	S70_07620 S70_07980

PSX:	DR96_1583(iunh) DR96_1657(iunh)

PSTA:

BGK56_10690(rihB) BGK56_11035(rihB)

PTHA:

OI982_15160 OI982_15525

PRG:	RB151_005310(rihB_1) RB151_006040(rihB_2)

PALA:

CO695_02205(rihB)

PHEI:

NCTC12003_00532(rihB_1) NCTC12003_00606(rihB_2)

PRQ:	CYG50_13085 CYG50_13410

PRJ:	NCTC6933_00597(rihB)

PVC:	G3341_02765

PMAG:

JI723_02835

PHAG:

PZ638_02510 PZ638_02840

PZJ:	QS795_002260

MMK:

MU9_3505

MWI:	MNY66_13470

PRAG:

EKN56_09690

PFQ:	QQ39_07965(rihB)

LRI:	NCTC12151_01619(rihA_2)

LGB:	V8L73_10775

HIA:

H733_0385

HSEM:

L3077_02775

HPAZ:

K756_00565

HPAS:

JL26_11285(rihB)

GLE:	CJD39_07640(rihB)

PMU:	PM1767(iunH)

PMV:	PMCN06_1590(rihA)

PUL:	NT08PM_1629

PMP:	Pmu_15710(rihA)

PMUL:

DR93_173(iunh)

PDAG:

4362423_01923(rihA)

PCAI:

K7G93_001515

MHT:	D648_25390(rihB)

MHAM:

J450_06965(rihB)

MVR:

X781_90

MVI:	X808_21170

MVG:	X874_19840

MVE:

X875_70

MGRA:

A4G16_09705(rihB)

MBOS:

ICJ55_02225

MPEG:

HV560_02405

MANN:

GM695_02255(rihB)

BTO:

WQG_19990

BTRE:

F542_2600

BTRH:

F543_3260

BTRA:

F544_19800

IGN:	MMG00_06785

GAP:	GAPWK_2308

GAQ:	RAM11_11165

ORB:	IPMB12_04025

AMAH:

DLM_3767

AQS:	DKK66_08580(rihB)

SUTT:

SUTMEG_09430(rihB2)

SUTK:

FG381_03520

SWS:	I6J16_02820

MLO:

mlr2009

MLN:	A9174_16725(rihB)

MAMO:

A6B35_16025(rihB)

MESP:

C1M53_08220(rihB)

MHUA:

MCHK_3547(rihB)

MJR:	EB229_16970

BRUC:

LJ361_11185

THD:	BHV28_08660

BHAI:

KJK41_01530

SFOR:

QNH23_02680

LSA:	LCA_0252(iunH1)

LCV:	FBA2_01505(rihB)

LGM:	LG542_07830

VAH:	G7081_06915

VIE:	OL234_06190

CCU:	Ccur_04420

ERZ:	ER308_07935

CGL:	Cgl1364(Cgl1364)

CGB:	cg1543(iunH3)

CGU:	WA5_1309(IunH3)

CGT:

cgR_1429

CGS:	C624_07630

CGG:	C629_07640

CGM:	cgp_1543(uriH)

CGJ:	AR0_07345(rihB)

CGQ:	CGLAR1_07210(rihB)

CGX:	SB89_07040(rihB)

CEF:

CE1482

CDI:	DIP1753(iunH)

CDP:	CD241_1688(iunH)

CDH:	CDB402_1642(iunH)

CDT:	CDHC01_1691(iunH)

CDE:	CDHC02_1625(iunH)

CDR:	CDHC03_1654(iunH)

CDA:	CDHC04_1650(iunH)

CDZ:	CD31A_1759(iunH)

CDB:	CDBH8_1726(iunH)

CDS:	CDC7B_1740(iunH)

CDD:	CDCE8392_1651(iunH)

CDW:	CDPW8_1748(iunH)

CDV:	CDVA01_1616(iunH)

CDIP:

ERS451417_01773(iunH)

CJK:	jk2078(iunH2)

CUR:

cu2003

CUA:	CU7111_1922(iunH2)

CPU:	CPFRC_08990

CPL:	Cp3995_1823(iunH2)

CPG:	CP316_09195

CPP:	CpP54B96_1804(iunH2)

CPK:	CP1002_04160

CPQ:	CPC231_08985

CPX:	CPI19_08995

CPZ:	CpPAT10_1776(iunH2)

COR:	Cp267_1844(iunH2)

COP:	CP31_09410

COD:	Cp106_1733(iunH2)

COS:	Cp4202_1765(iunH2)

COI:	CPCIP5297_09205

COE:	CP258_09205

COU:	CP162_09190

CPSE:

CPTA_00156

CPSU:

CPTB_01373

CPSF:

CPTC_01043

CRD:	CRES_2155(uriH)

CUL:	CULC22_02001(iunH1)

CUC:	CULC809_01845(iunH1)

CUE:	CULC0102_1992(iunH1)

CUN:	Cul210932_1973

CUQ:	Cul210931_1918

CUZ:	Cul05146_1961

CUJ:	CUL131002_1885c

CUS:	CulFRC11_1863

CHN:	A605_10090

CCN:	H924_06285

CAZ:	CARG_07280

CFN:	CFAL_11740

CCG:	CCASEI_01415

CII:	CIMIT_08650(rihB)

CUV:	CUREI_08345(rihB)

CMQ:	B840_10495(iunH)

CKU:	UL82_03785

CCJ:	UL81_08360

CTED:

CTEST_09395(IUNH)

CUT:	CUTER_08360(NSNH)

CLW:	CLAC_08435(rihB)

CDX:	CDES_06590(nsnH)

CSP:

WM42_2517

CSTA:

CSTAT_01085

CAQU:

CAQU_05165(rihB)

CAMG:

CAMM_01065

CPEG:

CPELA_01710(rihA1)

CGK:	CGERO_01660(rihA1)

CRF:	FRC0190_01780(rihB)

CRL:	NCTC7448_00168(rihB)

CPSO:

CPPEL_01580(rihA1)

CSUR:

N24_1449

CCYS:

SAMEA4530656_2258(rihB)

CMAT:

HBA49_09640

CYZ:	C3B44_02440(rihB)

CKF:	I6I12_09920

CLIA:

C3E79_04580

CUO:	CUROG_10430(rihA)

CSIL:

CBE74_10195

CTUB:

I6I74_08070

CLUJ:

IAU68_08395

CQN:	G7Y29_04405

CCOE:

CETAM_11150(rihB)

COK:	COCCU_00675(rihB)

CZO:	IAU67_09750

CMF:	GWO64_009225

CWK:	IA203_08640

CUW:	LH390_08335

CPOY:

GP475_00525(rihB)

CACC:

CACC_03305(rihB)

CPSL:

KBP54_07915

CJH:	CJEDD_08715(rihB)

CHEI:

CHEID_10390(rihA2)

CIHU:

CIHUM_07875(rihB)

CCOY:

CCOY_08675(rihB)

CHAD:

CHAD_08665(rihB)

CAUI:

CAURIS_08010(rihB)

CFAC:

CFAEC_06470(rihB)

CFOU:

CFOUR_07995(rihB)

CAUS:

CAURIC_11285(rihA)

CATR:

CATRI_09180(rihB)

CCOU:

CCONF_08310(rihA3)

CHAN:

CHAN_06085(rihB)

CAFE:

CAFEL_07850(rihB)

CGF:	CGUA_01510(rihB)

CGOI:

CGOTT_08335(rihB)

CBOV:

CBOVI_10445(rihA)

CSUE:

QP029_13635

CPYR:

CYJ47_12530

CORN:

BJP05_03135(rihB)

BFV:	C628_07505

RHW:	BFN03_18510(rihB)

SVT:	SVTN_35720(rihB)

STRE:

GZL_01601

SLD:

T261_7401

SLC:	SL103_21850(rihB)

SPRI:

SPRI_6313

SRN:	A4G23_05308(rihA)

SCLF:

BB341_27060(rihB)

SALW:

CP975_33085

SNR:	SNOUR_06775

SALU:

DC74_7040

SALL:

SAZ_36525(rihB)

SSIA:

A7J05_02395(rihB)

SGV:	B1H19_06985(rihB)

SALF:

SMD44_00523

SLX:	SLAV_35165(rihA)

STRO:

STRMOE7_33715(rihB)

SFK:

KY5_7880

SLK:	SLUN_31435

STIR:

DDW44_29330

SGZ:	C0216_17665

SVN:	CP980_31400

SFIC:

EIZ62_15555

SSPO:

DDQ41_00675

SRIM:

CP984_37685

SSUB:

CP968_04010

SGX:	H4W23_19560

SSPB:

CP982_40355

SNF:	JYK04_00951(rihA)

SPLA:

CP981_34160 CP981_36425

SATA:

C5746_34880(rihB)

SDW:	K7C20_32985

SVD:	CP969_31565

SAUH:

SU9_030565

SFB:	CP974_28270

SPRA:

CP972_30250

SPEU:

CGZ69_04725

SHK:	J2N69_35140

SANU:

K7396_04105

SINE:

KI385_38475

SAOV:

G3H79_38255

SYAN:

NRK68_29610

STAA:

LDH80_36210

SNIG:

HEK616_42370

STUB:

MMF93_31885

SXT:	KPP03845_106267(rihA)

STUD:

STRTU_000584

SENG:

OJ254_25815

SYUN:

MOV08_06685

SHAU:

K9S39_39610

SFP:	QUY26_37925

STTN:

BSL84_29195

SCAY:

PYS65_04920

SRPA:

HEP86_35705 HEP86_38755

SMIB:

SMIR_24810

STRI:

C7M71_004880

LEIF:

HF024_13325

LSE:	F1C12_18425

LEIZ:

IT072_01330

CMI:	CMM_0982(iunH)

CMH:	VO01_03765(rihB)

CMS:

CMS2856

CMC:	CMN_00944(iunH)

CCAP:

AES38_04445(rihB)

CZH:	H9X71_04535

CPHA:

FGI33_08385

CCAF:

FGD68_06980

MIP:	AXH82_06920

MOY:	CVS54_00038(rihA)

MPAO:

IZR02_00180

MNF:	JSY13_00545

MHOT:

PU630_16240

CUM:	NI26_01530(rihB)

CUB:	BJK06_06500(rihB)

CUG:	C1N91_01305(rihB)

CCIT:

QPK07_01630

CUY:	I8920_01540

CPOI:

OE229_04460

MVD:	AWU67_15210(rihB) AWU67_16135

FRP:	AX769_04360(rihB)

FSB:	GCM10025867_16510(rihB2)

AGY:	ATC03_18235

AGM:	DCE93_13520

AGF:	ET445_05050

AMAU:

DSM26151_27670(rihA)

ALAV:

MTO99_13165

AIL:	FLP10_10120

CPHY:

B5808_12990(rihB)

PSAI:

C3B54_111325

MALK:

MalAC0309_2336

CHRE:

IE160_10215

MHUM:

NNL39_02815

MDB:	OVN18_02520

MSPO:

KXZ72_14180

SALA:

ESZ53_12610

HUM:	DVJ78_07775

GRY:	D7I44_03540

PLAP:

EAO79_18235

PFLU:

BWO91_14965(rihB)

LLUT:

K1X41_14980

LARI:

KI794_15680

AGG:	C1N71_03505(rihB)

MANT:

BHD05_00120(rihB)

HEA:	HL652_13155

HEH:	L3i23_04700

GLN:	F1C58_02825

SUBT:

KPL76_06515

SUBA:

LQ955_12065

NAEI:

GCM126_17600

AOG:	LH407_10405

ART:

Arth_0081

ARR:	ARUE_c37820

ARM:

ART_2564

ARL:	AFL94_00175(rihB)

ARE:	AL755_00800(rihB)

AAQ:	AOC05_16330(rihB)

ARW:	MB46_15430(rihB)

ARH:	AHiyo8_40240

ARY:	ATC04_00490(rihB)

ARZ:	AUT26_17385(rihB)

ARN:	CGK93_10740(rihB) CGK93_20420(rihB)

ARX:	ARZXY2_105(iunH)

ARTP:

E5206_01840

AJG:	KKR91_03165

ASUN:

KG104_02895

ASUF:

MNQ99_18020

APOA:

J0916_14160

AWW:	G8758_15345

ACAO:

NF551_03180

AZH:	MUK71_02660

AGEG:

MUG94_02780

AKO:	N9A08_15005

AZX:	N2K95_02615

AJR:	N2K98_02485

AAU:

AAur_3646

PUE:	FV140_19005

PNV:	JMY29_17570

PAYJ:

HMI59_02970

PAGO:

IRJ34_18050

ACH:

Achl_0185

PSUL:

AU252_09535(rihB)

PSNI:

NIBR502771_04585

PSEY:

GU243_15290(rihB)

PDEL:

JCQ34_00620

PSFE:

NG819_02795

AAI:	AARI_00440(iunH)

GAR:	AOZ07_00165(rihB)

GCR:	GcLGCM259_0035(rihA)

GLU:	F0M17_00175

GPR:	JQN66_00190

GMI:	NMP99_00175

GMY:

XH9_08355

GNC:	QQS42_00180

GLM:	N6V40_02550

RSA:	RSal33209_3202

KPL:	KPaMU14_01415(rihB)

PAEY:

KUF55_02405

BKI:	M4486_16410

BHH:	Bra3105_13225

CET:	B8281_07820(rihB)

CCEU:

CBR64_03555(rihB)

CPRT:

FIC82_006555

CIRA:

LFM56_12670

CCHE:

NP064_00475

OCP:	NF557_13055

GEZ:	FE251_05085

GYU:	FE374_07980

PACD:

EGX94_05810

PAUS:

NCTC13651_02686(rihB)

MIK:	FOE78_16380

TFA:	BW733_16375(rihB)

BRT:	J4N02_06905

NCX:	Nocox_39795(rihA)

NFS:	OIE67_52105

TBI:

Tbis_2587

MHAI:

OHB01_35725

NAK:	EH165_11875

NAKA:

H7F38_12085

SEN:	SACE_1231(ybeK)

PSEA:

WY02_06685(rihB)

PSEE:

FRP1_15700(rihB)

PSEH:

XF36_08105(rihB)

PSEQ:

AD006_23345(rihB)

PECQ:

AD017_02935(rihB)

PSDS:

K1T35_03950

KAL:

KALB_6377

LED:	BBK82_42030

ASIC:

Q0Z83_075020(rihA)

ACTE:

ACTI_33520(rihA)

AFS:

AFR_15095

PFLA:

Pflav_090800

PSUU:

Psuf_053610(rihA)

ARCA:

HC352_07725

TPY:	CQ11_05755(rihB)

TPYO:

X956_01930(rihB)

TPEC:

HLG82_01125

ASG:	FB03_00490(rihB)

AUU:	CJ184_003460

ATIM:

CYJ17_0005385

ACTP:

B6G06_00500(rihB)

ACTC:

CHIBA101_2317

AMAM:

HPC72_09555

AGH:	M3I41_01030

AMAS:

QU670_12970

FLH:	EJ997_01295

WIK:	H8R18_05055

WNE:	PIG85_01060

VCB:	CYK25_001735

BLN:

Blon_0638

BLON:

BLIJ_0643

BLA:	BLA_0639(iunH)

BLC:	Balac_1438

BLT:	Balat_1438

BBB:

BIF_01895

BBC:

BLC1_1394

BNM:	BALAC2494_01296

BLV:

BalV_1394

BLW:

W7Y_1436

BLS:

W91_1471

BANI:

BL12_07200

BANL:

BLAC_07285

BANM:

EN10_07275(rihB)

BAST:

BAST_1182

BKA:	AH68_02970(rihB)

BPSP:

AH67_03305(rihB)

BPSC:

BBPC_0569

BACT:

AB656_04210(rihB)

GVG:	HMPREF0421_21146

GVA:	HMPREF0424_0319

GVH:	HMPREF9231_0391

GPT:	K9E43_04850

GSW:	K9E37_04730

SIJ:

SCIP_0944

PDO:

PSDT_0554

BAPK:

KIMH_11290(rihB2)

BNK:	KIM372_05320(rihB2)

EKE:	EK0264_09080

KBB:	ccbrp13_65270

» show all

Reference

1 [PMID:13376622]

Authors

KOCH AL.

Title

Some enzymes of nucleoside metabolism of Escherichia coli.

Journal

J Biol Chem 223:535-49 (1956)

Reference

2 [PMID:14363106]

Authors

TARR HL.

Title

Fish muscle riboside hydrolases.

Journal

Biochem J 59:386-91 (1955)
DOI:10.1042/bj0590386

Other DBs

ExplorEnz - The Enzyme Database:

3.2.2.2

IUBMB Enzyme Nomenclature:

3.2.2.2

ExPASy - ENZYME nomenclature database:

3.2.2.2

BRENDA, the Enzyme Database:

3.2.2.2

CAS:

9030-95-9

DBGET integrated database retrieval system