Entry
Name
futalosine hydrolase;
futalosine nucleosidase;
MqnB (ambiguous)
Class
Hydrolases;
Glycosylases;
Hydrolysing N-glycosyl compounds
BRITE hierarchy
Sysname
futalosine ribohydrolase
Reaction(IUBMB)
futalosine + H2O = dehypoxanthine futalosine + hypoxanthine [RN:
R08587 ]
Reaction(KEGG)
Substrate
Product
dehypoxanthine futalosine [CPD:
C17010 ];
hypoxanthine [CPD:
C00262 ]
Comment
This enzyme, which is specific for futalosine, catalyses the second step of a novel menaquinone biosynthetic pathway that is found in some prokaryotes.
History
EC 3.2.2.26 created 2008
Pathway
ec00130 Ubiquinone and other terpenoid-quinone biosynthesis
ec01110 Biosynthesis of secondary metabolites
Orthology
Genes
GEC : GEO60473_33230(mqnB)
GBN : GEOBRER4_06040(mqnB)
PPOR : JCM14722_13700(mqnB)
COHN : KCTCHS21_47820(mqnB)
SALS : SLNWT_0701 SLNWT_4242
SAMB : SAM23877_3378(mqnB)
SLE : sle_39460(sle_39460)
SGM : GCM10017557_37400(mqnB)
STUI : GCM10017668_30880(mqnB)
SXT : KPP03845_104254(mqnB)
STRI : C7M71_012745 C7M71_025715
DVC : Dvina_31125 Dvina_50640
DAUR : Daura_29740 Daura_49170
DMAT : Dmats_26155 Dmats_45230
DEIN : DAAJ005_06390(mqnB)
LCRE : Pla8534_45380(mqnB)
» show all
Taxonomy
Reference
Authors
Hiratsuka T, Furihata K, Ishikawa J, Yamashita H, Itoh N, Seto H, Dairi T
Title
An alternative menaquinone biosynthetic pathway operating in microorganisms.
Journal
Sequence
Other DBs
ExplorEnz - The Enzyme Database: 3.2.2.26
ExPASy - ENZYME nomenclature database: 3.2.2.26