| Entry |
|
|---|
| Name |
S-adenosyl-L-methionine hydrolase (L-homoserine-forming);
S-adenosylmethionine cleaving enzyme;
methylmethionine-sulfonium-salt hydrolase;
adenosylmethionine lyase;
adenosylmethionine hydrolase;
S-adenosylmethionine hydrolase;
S-adenosyl-L-methionine hydrolase
|
|---|
| Class |
Hydrolases;
Acting on ether bonds;
Thioether and trialkylsulfonium hydrolases
|
|---|
| Sysname |
S-adenosyl-L-methionine hydrolase (L-homoserine-forming)
|
|---|
| Reaction(IUBMB) |
S-adenosyl-L-methionine + H2O = L-homoserine + S-methyl-5'-thioadenosine [RN: R00175]
|
|---|
| Reaction(KEGG) |
|
|---|
| Substrate |
|
|---|
| Product |
L-homoserine [CPD: C00263];
S-methyl-5'-thioadenosine [CPD: C00170]
|
|---|
| Comment |
Also hydrolyses S-methyl-L-methionine to dimethyl sulfide and homoserine. cf. EC 3.13.1.8, S-adenosyl-L-methionine hydrolase (adenosine-forming).
|
|---|
| History |
EC 3.3.1.2 created 1972, modified 1976, modified 2018
|
|---|
| Orthology |
| K21534 | S-adenosyl-L-methionine hydrolase (L-homoserine-forming) |
|
|---|
| Reference |
|
|---|
| Authors |
Mazelis M, Levin B, Mallinson N. |
|---|
| Title |
Decomposition of methyl methionine sulfonium salts by a bacterial enzyme. |
|---|
| Journal |
|
|---|
| Other DBs |
| ExplorEnz - The Enzyme Database: | 3.3.1.2 |
| ExPASy - ENZYME nomenclature database: | 3.3.1.2 |
| BRENDA, the Enzyme Database: | 3.3.1.2 |
|
|---|
