KEGG   ENZYME: 3.4.11.14Help
Entry
EC 3.4.11.14                Enzyme                                 

Name
cytosol alanyl aminopeptidase;
arylamidase;
aminopolypeptidase;
thiol-activated aminopeptidase;
human liver aminopeptidase;
puromycin-sensitive aminopeptidase;
soluble alanyl aminopeptidase;
cytosol aminopeptidase III;
alanine aminopeptidase
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Aminopeptidases
BRITE hierarchy
Reaction(IUBMB)
Release of an N-terminal amino acid, preferentially alanine, from a wide range of peptides, amides and arylamides
Comment
A puromycin-sensitive, Co2+-activated zinc-sialoglycoprotein that is generally cytosolic. Multiple forms are widely distributed in mammalian tissues and body fluids. In peptidase family M1 (membrane alanyl aminopeptidase family)
History
EC 3.4.11.14 created 1978
Orthology
K01263  cytosol alanyl aminopeptidase
Genes
EHI: EHI_158320(242.t00016)
TBR: Tb927.7.6270
TCR: 506513.110
LMA: LMJF_17_0140
LIF: LINJ_17_0250
XCC: XCC3168(pepN)
XCB: XC_0997
XCA: xcc-b100_1009(pepN)
XCP: XCR_3507
XCV: XCV3437(pepN3)
XAX: XACM_3213(pepN3)
XAC: XAC3318(pepN)
XCI: XCAW_01008(pepN)
XOO: XOO3393(pepN)
XOM: XOO3194(XOO3194)
XOP: PXO_01920
XOR: XOC_3565
PSD: DSC_12180
ACB: A1S_2356
ABM: ABSDF1167
ABY: ABAYE1122
ABN: AB57_2787
ABX: ABK1_2670
ABH: M3Q_2820
ABAD: ABD1_23530
ABAZ: P795_5135
ABAU: IX87_08530
ABAA: IX88_15085
ACC: BDGL_001845(ape1)
SWD: Swoo_2381
SWP: swp_2519
SVO: SVI_2133
PAT: Patl_1912
PSM: PSM_A0515
KKO: Kkor_2199
CFU: CFU_3654
LJO: LJ_0645
LGA: LGAS_1652
 » show all
Taxonomy
Reference
1  [PMID:4841062]
  Authors
Starnes WL, Behal FJ.
  Title
A human liver aminopeptidase. The amino acid and carbohydrate content, and some physical properties of a sialic acid containing glycoprotein.
  Journal
Biochemistry 13:3221-7 (1974)
Reference
2  [PMID:698181]
  Authors
Kao YJ, Starnes WL, Behal FJ.
  Title
Human kidney alanine aminopeptidase: physical and kinetic properties of a sialic acid containing glycoprotein.
  Journal
Biochemistry 17:2990-4 (1978)
Reference
3  [PMID:6108169]
  Authors
Sidorowicz W, Hsia WC, Maslej-Zownir O, Behal FJ.
  Title
Multiple molecular forms of human alanine aminopeptidase: immunochemical properties.
  Journal
Clin Chim Acta 107:245-56 (1980)
DOI:10.1016/0009-8981(80)90452-0
Other DBs
ExplorEnz - The Enzyme Database: 3.4.11.14
IUBMB Enzyme Nomenclature: 3.4.11.14
ExPASy - ENZYME nomenclature database: 3.4.11.14
BRENDA, the Enzyme Database: 3.4.11.14
CAS: 243859-94-1

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