EC                 Enzyme                                 

aminopeptidase B;
arylamidase II;
arginine aminopeptidase;
arginyl aminopeptidase;
Cl--activated arginine aminopeptidase;
cytosol aminopeptidase IV;
L-arginine aminopeptidase
Acting on peptide bonds (peptidases);
BRITE hierarchy
Release of N-terminal Arg and Lys from oligopeptides when P1' is not Pro. Also acts on arylamides of Arg and Lys
Cytosolic or membrane-associated enzyme from mammalian tissues, activated by chloride ions and low concentrations of thiol compounds. This is one of the activities of the bifunctional enzyme EC (membrane alanyl aminopeptidase family) [4,5].
EC created 1972, modified 1997
K01260  aminopeptidase B
K19701  aminopeptidase YwaD
HSA: 6051(RNPEP)
PTR: 469638(RNPEP)
PPS: 100974364(RNPEP)
GGO: 101127560(RNPEP)
PON: 100456066(RNPEP)
MCC: 706696(RNPEP)
MCF: 102146949(RNPEP)
CSAB: 103230319(RNPEP)
RRO: 104674517(RNPEP)
RBB: 108545095(RNPEP)
CJC: 100400846(RNPEP)
SBQ: 101049218(RNPEP)
MMU: 215615(Rnpep)
MCAL: 110291497(Rnpep)
MPAH: 110321199(Rnpep)
RNO: 81761(Rnpep)
MUN: 110548421(Rnpep)
CGE: 100755451(Rnpep)
NGI: 103731828(Rnpep)
HGL: 101712935(Rnpep)
CCAN: 109684759(Rnpep)
OCU: 100342982(RNPEP)
TUP: 102475581(RNPEP)
CFA: 490236(RNPEP)
VVP: 112934502(RNPEP)
AML: 100471332(RNPEP)
UMR: 103657779(RNPEP)
UAH: 113242543(RNPEP)
ORO: 101367496(RNPEP)
FCA: 101100613(RNPEP)
PTG: 102952170(RNPEP)
PPAD: 109256296(RNPEP)
AJU: 106974256(RNPEP)
BTA: 282040(RNPEP)
BOM: 102286299(RNPEP)
BBUB: 102409731(RNPEP)
CHX: 102170601(RNPEP)
OAS: 101114205(RNPEP)
SSC: 100524577(RNPEP)
CFR: 102505914(RNPEP)
CDK: 105103112(RNPEP)
BACU: 103013646(RNPEP)
LVE: 103076101(RNPEP)
OOR: 101290438(RNPEP)
DLE: 111168315(RNPEP)
PCAD: 102985050(RNPEP)
ECB: 100063775(RNPEP)
EPZ: 103567457(RNPEP)
EAI: 106832344(RNPEP)
MYB: 102246228(RNPEP)
MYD: 102760506(RNPEP)
MNA: 107536014(RNPEP)
HAI: 109380478(RNPEP)
DRO: 112318852(RNPEP)
MJV: 108405428(RNPEP)
LAV: 100673954(RNPEP)
TMU: 101342405
MDO: 100014545(RNPEP)
SHR: 100923693(RNPEP)
PCW: 110219603(RNPEP)
OAA: 100093099(RNPEP)
GGA: 421165(RNPEP)
MGP: 100549291(RNPEP)
CJO: 107324639(RNPEP)
NMEL: 110388359(RNPEP)
APLA: 101802986(RNPEP)
ACYG: 106045854(RNPEP)
TGU: 100224003(RNPEP)
LSR: 110469199(RNPEP)
SCAN: 103822440(RNPEP)
GFR: 102036435(RNPEP)
FAB: 101813510(RNPEP)
PHI: 102112448(RNPEP)
PMAJ: 107214916(RNPEP)
CCAE: 111939603(RNPEP)
CCW: 104692573(RNPEP)
ETL: 114064786(RNPEP)
FPG: 101914529(RNPEP)
FCH: 102048572(RNPEP)
CLV: 102090773(RNPEP)
EGZ: 104122020(RNPEP)
NNI: 104011102(RNPEP)
ACUN: 113488958(RNPEP)
PADL: 103913823(RNPEP)
AAM: 106500249(RNPEP)
ASN: 102369662(RNPEP)
AMJ: 102561220(RNPEP)
PSS: 102450932(RNPEP)
CMY: 102931368(RNPEP)
CPIC: 101946561(RNPEP)
ACS: 100554554(rnpep)
PVT: 110073333(RNPEP)
PBI: 103063102(RNPEP)
PMUR: 107295845(RNPEP)
TSR: 106544931(RNPEP)
PMUA: 114599423(RNPEP)
GJA: 107121706(RNPEP)
XLA: 443974(rnpep.S) 447741(rnpep.L)
XTR: 407876(rnpep)
NPR: 108795716(RNPEP)
DRE: 437014(rnpep)
CCAR: 109098332 109100480(rnpep)
PHYP: 113539473(rnpep)
AMEX: 103045130(rnpep)
EEE: 113578925(rnpep)
SASA: 100195514(rnpep)
OTW: 112216049(rnpep)
SALP: 111965278(rnpep)
ELS: 105016934(rnpep)
PKI: 111839897(rnpep)
LCM: 102364673(RNPEP)
CMK: 103179129(rnpep)
RTP: 109916000(rnpep)
SPU: 588993
SKO: 100372225
PCAN: 112575395
MYI: 110440307
BSU: BSU38470(ywaD)
BSR: I33_4001
BSL: A7A1_2084
BSH: BSU6051_38470(ywaD)
BSUT: BSUB_04085(ywaD)
BSUL: BSUA_04085(ywaD)
BSUS: Q433_21180
BSS: BSUW23_19060(ywaD)
BST: GYO_4245
BSO: BSNT_10509(ywaD)
BSQ: B657_38470(ywaD)
BSX: C663_3758(ywaD)
BLI: BL03935(ywaD)
BLD: BLi04074(ywaD)
BLH: BaLi_c40830(ywaD)
BAQ: BACAU_3151(ywaD1)
BAMP: B938_16010
BAML: BAM5036_3039(ywaD)
BAMA: RBAU_3260(ywaD)
BAMN: BASU_3041(ywaD)
BAMT: AJ82_17655
BAMY: V529_33860
BAO: BAMF_3251(ywaD)
BAZ: BAMTA208_17260(ywaD)
BQL: LL3_03534(ywaD)
BXH: BAXH7_03525(ywaD)
BAMI: KSO_003505
BAMC: U471_32420
BAMF: U722_16775
BHA: BH3861
BAN: BA_5606
BAR: GBAA_5606
BAT: BAS5208
BAI: BAA_5632
BANT: A16_56160
BANR: A16R_56850
BANV: DJ46_4254
BCE: BC5359
BCA: BCE_5488
BCQ: BCQ_5199
BCX: BCA_5508
BNC: BCN_5287
BCF: bcf_26900
BCER: BCK_08560
BTL: BALH_4856
BTT: HD73_5768
BTHI: BTK_28440
BTM: MC28_4594
BTG: BTB_c55600(ywaD)
BTW: BF38_1082
BWW: bwei_4420(ywaD)
BMYO: BG05_646
BMYC: DJ92_2450(ywaD)
BMQ: BMQ_2033(ywaD)
BMD: BMD_1989(ywaD)
BMH: BMWSH_3244(ywaD)
BMEG: BG04_4334(amp)
BJS: MY9_3952
BACP: SB24_13125
BACY: QF06_17685
BACL: BS34A_41670(ywaD)
BALM: BsLM_3881
BEO: BEH_16595
BGY: BGLY_4528(ywaD)
JEO: JMA_03500
ACTI: UA75_21805
ACAD: UA74_21325
AHG: AHOG_18820(ywaD)
DMC: btf_974
ABAC: LuPra_01172(ywaD_1)
CHZ: CHSO_2503
LOKI: Lokiarch_24450(ywaD_3)
 » show all
1  [PMID:6434344]
Gainer H, Russell JT, Loh YP.
An aminopeptidase activity in bovine pituitary secretory vesicles that cleaves the N-terminal arginine from beta-lipotropin60-65.
FEBS Lett 175:135-9 (1984)
2  [PMID:8344358]
Belhacene N, Mari B, Rossi B, Auberger P.
Characterization and purification of T lymphocyte aminopeptidase B: a putative marker of T cell activation.
Eur J Immunol 23:1948-55 (1993)
3  [PMID:7672445]
Cadel S, Pierotti AR, Foulon T, Creminon C, Barre N, Segretain D, Cohen P.
Aminopeptidase-B in the rat testes: isolation, functional properties and cellular localization in the seminiferous tubules.
Mol Cell Endocrinol 110:149-60 (1995)
4  [PMID:8940051]
Fukasawa KM, Fukasawa K, Kanai M, Fujii S, Harada M.
Molecular cloning and expression of rat liver aminopeptidase B.
J Biol Chem 271:30731-5 (1996)
5  [PMID:9096329]
Cadel S, Foulon T, Viron A, Balogh A, Midol-Monnet S, Noel N, Cohen P.
Aminopeptidase B from the rat testis is a bifunctional enzyme structurally related to leukotriene-A4 hydrolase.
Proc Natl Acad Sci U S A 94:2963-8 (1997)
6  [PMID:8157657]
Orning L, Gierse JK, Fitzpatrick FA.
The bifunctional enzyme leukotriene-A4 hydrolase is an arginine aminopeptidase of high efficiency and specificity.
J Biol Chem 269:11269-73 (1994)
Other DBs
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CAS: 9073-92-1

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